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Objective: Hyperglycemia is common in hospitalized patients with both medical and surgical pathologies and is associated with increased morbidity and hospital mortality. The objective of this study is to confirm this association in patients hospitalized in a critical care unit. Materials and Methods: A cross-sectional study was performed with a population of hospitalized patients in critical care units Clínica Versalles during the years 2010 to 2011. The following variables was analyzed: age, hyperglycemia, acute coronary syndromes, cerebrovascular disease, infectious and noninfectious complications. Results: Hyperglycemia defined as fasting glucose above 140 mg / dl was found in 26%. Using the X² procedure tested the relationship between hyperglycemia and co morbidities such as non-infectious acute coronary syndrome, cerebrovascular disease, respiratory failure and renal failure (p = 0.038). The level of hyperglycemia was higher in patients with previously undiagnosed diabetes (p = 0.000). Using Pearson correlation coefficients were found significant association between the value of hyperglycemia and age (p = 0.00). Conclusions: Results support the relationship between hyperglycemia and adverse hospital outcomes. [ABSTRACT FROM AUTHOR]