1. Seroprevalence of the SARS-CoV-2 antibody in healthcare workers: a multicentre cross-sectional study in 10 Colombian cities.
- Author
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Malagón-Rojas JN, Mercado-Reyes M, Toloza-Pérez YG, Parra Barrera EL, Palma M, Muñoz E, López R, Almentero J, Rubio VV, Ibáñez E, Téllez E, Delgado-Murcia LG, Jimenez CP, Viasus-Pérez D, Galindo M, and Lagos L
- Subjects
- Antibodies, Viral, Bayes Theorem, Cities epidemiology, Colombia epidemiology, Cross-Sectional Studies, Health Personnel, Humans, Immunoglobulin G, Seroepidemiologic Studies, COVID-19 epidemiology, SARS-CoV-2
- Abstract
Background: Healthcare workers are at increased risk of infection due to occupational exposure to SARS-CoV-2-infected patients. The objective of this study was to determine the seroprevalence of SARS-CoV-2 in healthcare workers in Colombia., Methods: This study is a cross-sectional study focused on estimating the seroprevalence of SARS-CoV-2 antibodies in healthcare workers from 65 hospitals in 10 cities in Colombia during the second semester of 2020. The seroprevalence was determined using an automated immunoassay (Abbott SARS-CoV-2 CLIA IgG). The study included a survey to establish the sociodemographic variables and the risk of infection. A multivariate model was used to evaluate the association between the results of seroprevalence and risk factors., Results: The global seroprevalence of antibodies against SARS-CoV-2 was 35% (95% Bayesian CI 33% to 37%). All the personnel reported the use of protective equipment. General services personnel and nurses presented the highest ratios of seroprevalence among the healthcare workers. Low socioeconomic strata have shown a strong association with seropositivity., Conclusion: This study estimates the prevalence of SARS-CoV-2 infection among healthcare workers. Even though all the personnel reported the use of protective equipment, the seroprevalence in the general services personnel and nurses was high. Also, a significant difference by cities was observed., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
- Published
- 2022
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