1. Withanolides from three species of the genus Deprea (Solanaceae). Chemotaxonomical considerations.
- Author
-
Casero CN, Oberti JC, Orozco CI, Cárdenas A, Brito I, Barboza GE, and Nicotra VE
- Subjects
- Colombia, Crystallography, X-Ray, Molecular Conformation, Molecular Structure, Nuclear Magnetic Resonance, Biomolecular, Plant Components, Aerial chemistry, Solanaceae classification, Solanaceae genetics, Withanolides chemistry, Solanaceae chemistry, Withanolides isolation & purification
- Abstract
Nine withanolides were isolated from the aerial parts of Deprea bitteriana, Depreacuyacensis, and Depreazamorae. D.bitteriana yielded two withaphysalins, D. cuyacensis gave two 13,14-seco withaphysalins, while D. zamorae yielded five physangulidines. The compounds were fully characterized by a combination of spectroscopic methods (1D and 2D NMR and MS). All compounds isolated from D.bitteriana and D. cuyacensis were obtained as epimeric mixtures at C-18. The structure of physangulidine D was confirmed by X-ray diffraction analysis. The skeletons found in this research support the chemotaxonomical position of the genus Deprea in the tribe Physalideae., (Copyright © 2014 Elsevier Ltd. All rights reserved.)
- Published
- 2015
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