1. Estimating the percentage of European MSM eligible for PrEP: insights from a bio-behavioural survey in thirteen cities.
- Author
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Cordioli M, Gios L, Huber JW, Sherriff N, Folch C, Alexiev I, Dias S, Nöstlinger C, Gama A, Naseva E, Valkovičová Staneková D, Marcus U, Schink SB, Rosinska M, Blondeel K, Toskin I, and Mirandola M
- Subjects
- Adolescent, Adult, Anti-HIV Agents therapeutic use, Cities epidemiology, Europe, Humans, Male, Middle Aged, Surveys and Questionnaires, Young Adult, Anti-HIV Agents administration & dosage, HIV Infections epidemiology, HIV Infections prevention & control, Homosexuality, Male statistics & numerical data, Patient Acceptance of Health Care statistics & numerical data, Pre-Exposure Prophylaxis, Sexual Behavior statistics & numerical data
- Abstract
Objectives: This paper aims to estimate the percentage of European men who have sex with men (MSM) who may benefit from pre-exposure prophylaxis (PrEP), applying the three most widely used HIV risk indices for MSM (MSM Risk Index, Menza score, San Diego Early Test (SDET) score) and drawing on a large-scale multisite bio-behavioural survey (Sialon II)., Methods: The Sialon II study was a bio-behavioural survey among MSM implemented in 13 European cities using either time-location sampling or respondent-driven sampling. Biological and behavioural data from 4901 MSM were collected. Only behavioural data of HIV-negative individuals were considered. Three widely used risk indices to assess HIV acquisition risk among MSM were used to estimate individual HIV risk scores and PrEP eligibility criteria., Results: 4219 HIV-negative MSM were considered. Regardless the HIV risk score used and the city, percentages of MSM eligible for PrEP were found to range between 5.19% and 73.84%. Overall, the MSM Risk Index and the Menza score yielded broadly similar percentages, whereas the SDET Index provided estimates constantly lower across all cities. Although all the three scores correlated positively (r>0.6), their concordance was highly variable (0.01
- Published
- 2021
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