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A study conducted at Army Medical University in Chongqing, China, has found that microneedles loaded with dexamethasone and epigallocatechin-3-gallate (EGCG) can reverse the imbalance of subcutaneous immune homeostasis for the treatment of psoriasis. Psoriasis is an inflammatory skin condition characterized by dysregulation of the immune microenvironment, including reactive oxygen species (ROS) accumulation and T cell overactivation. The microneedles deliver the drugs directly to the lesion area, alleviating psoriasis-like manifestations and correcting the disorder of immune cells. This research offers insights for developing new antipsoriasis treatments. [Extracted from the article]

A report from the Chongqing Hospital of Traditional Chinese Medicine in China discusses a case of chorea, a movement disorder, in a 14-year-old girl with pediatric-onset systemic lupus erythematosus (SLE). The girl developed chorea after her glucocorticoid therapy was reduced. Her symptoms improved after adjusting her medication. The research emphasizes the need for careful monitoring of chorea in SLE patients during glucocorticoid dose reduction. [Extracted from the article]