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Based on non-economic field promotion tournament theory, this study examines the linkage between civilized cities commendation policy (CCCP) and urban green innovation (UGI). Using the panel data of 279 cities in China from 2003 to 2018, the difference-in-differences, propensity score matching difference-in-differences, and difference-in-differences spatial dobbin models are established to verify the hypotheses. The empirical results show that CCCP has a positive effect on UGI; innovation investments and innovation talents significantly mediate the relationship between CCCP and UGI; environmental governance intensity positively moderates the relationships between CCCP and UGI, innovation investments and UGI, as well as innovation talent agglomeration and UGI; and the influence of CCCP on UGI has a spatial spillover effect and a spatial attenuation boundary. These findings provide practical insights towards the improvement of urban evaluation and commendation systems, as well as green innovation. [ABSTRACT FROM AUTHOR]

Purpose: This study examines whether the national innovative city pilot policy (NICP) influences urban entrepreneurship (UE). To examine the underlying causal mechanism, this study modeled the city-level intellectual capital index and financing capacity (FC) in the relationship between NICP and UE. Design/methodology/approach: An empirical model of NICP, intellectual capital, FC and entrepreneurship is conceptualized based on theoretical analysis. Using a quasi-natural experiment of China's NICP, with a sample of 280 prefecture-level cities in China from 2003 to 2018, propensity score matching with difference-in-differences (PSM-DID) is used to empirically test the NICP's impact on UE, mediating effects of intellectual capital and moderation effects of FC. Findings: The results show that the NICP can significantly motivate UE. Intellectual capital plays mediating effects on the relationship between NICP and UE. Moreover, the NICP and intellectual capital's effects on UE are moderated by FC. Practical implications: This study provides an important reference for promoting UE through intellectual capital and FC in the construction of the NICP. Originality/value: This is a pioneering study that develops a theoretical model to incorporate NICP, intellectual capital, FC and UE. This paper applies experimental governance theory in innovative urban scenarios, and verifies its applicability and particularity in the Chinese context. [ABSTRACT FROM AUTHOR]

The construction of national innovation systems has been receiving increasing attention. The present study aims to examine whether national innovative city pilot policy (NICP) influences green technology progress. Using a sample of 285 prefecture-level cities in China from 2003 to 2018, propensity score matching with difference-in-difference (PSM-DID) is used to empirically examine the effect of NICP on green technology progress. Our findings indicate that NICP can positively affect green technology progress. Green technology progress is promoted through NICP, specifically by innovation investment enhancement and innovation elements aggregation. Environmental regulation positively moderates the relation between NICP and green technology progress. 1. This study adopts propensity score matching with difference-in-difference (PSM-DID) to investigate the effect of national innovative city pilot policy (NICP) on green technology progress. 2. The empirical results show that NICP can positively affect green technology progress. 3. Green technology progress is promoted through NICP, specifically by innovation investment enhancement and innovation elements aggregation. 4. Environmental regulation positively moderates the relation between NICP and green technology progress. [ABSTRACT FROM AUTHOR]

• Green innovation efficiency is calculated by Super efficiency slacks-based model. • Green innovation efficiencies of China's provinces have upward trends. • Environmental constraint target positively effects green innovation efficiency. • The mediating effect of industrial structure upgrading is verified. Green innovation has attracted more attention all over the world under the background of resource shortage and environmental pollution. This study explores effects of environmental constraint target on green innovation efficiency by super efficiency slacks-based measure (SBM), panel Tobit and instrumental variables-two stage least square (IV-2SLS) models. Our empirical evidence analyses 30 provinces, China from 2007 to 2018. Green innovation efficiencies of China's provinces show an upward trend, as well as performance a significant cluster effect. Moreover, this paper offers multiple empirical supports for the favorable impacts of environmental constraint target on green innovation efficiency. Finally, environmental constraint target promotes industrial structure upgrading significantly, and then achieves the improvement of green innovation efficiency. [ABSTRACT FROM AUTHOR]

As an important farmed fish worldwide, largemouth bass (Micropterus salmoides) is suffering a severely disease caused by rhabdovirus, which has resulted to a massive economic loss. In the present study, a new Micropterus salmoides rhabdovirus (MSRV) strain named MSRV-NY01 was isolated from largemouth bass juvenile from a fish farm in Nanyang, Henan province, China. Cell culture, histopathological examination, reverse transcription-polymerase chain reaction (RT-PCR), plaque purification, phylogenetic analysis, transmission electron micrograph (TEM) observation, experimental infection, real-time quantitative polymerase chain reaction (RT-qPCR) were used for virus isolation and identification. The diseased fish exhibited abnormal symptoms with anorexia, exophthalmia, bloated abdomen, spiral swimming, hemorrhage on body surfaces, and fluid accumulation in the abdominal cavity. Histopathological examination showed obvious hemorrhage, inflammatory cell infiltration, and widespread cell degeneration and necrosis were presented in the liver, spleen, intestine and stomach of diseased fish. Obvious cytopathic effects (CPE) were induced in epithelioma papillosum cyprini (EPC), grouper spleen (GS) and grouper fin (GF-1) cell lines after inoculation of mixed liver and kidney homogenates from disease fish. RT-PCR, DNA sequencing and phylogenetic tree analysis showed that the virus belongs to rhabdovirus with the highest similar to the MSRV-FJ985 strain. Through five sequential rounds of plaque purification assay, a MSRV plaque isolate was derived and was confirmed by RT-PCR and DNA sequencing. TEM observation showed that numerous virions with typical bullet shape (100–150 nm in length and 70–90 nm in diameter) were present in infected GS cells. Thus, this newly isolated virus from diseased Micropterus salmoides was tentatively named as MSRV-NY01. Regression infection experiment indicated that MSRV-NY01 was highly pathogenic to Micropterus salmoides juvenile and the cumulative mortality of fish injected with 5 × 104, 104, 2 × 103, 4 × 102, 2 × 102, 102 and 50 PFU of virus were 100%, 100%, 100%, 96.7%, 96.7%, 93.3% and 90%, respectively. Moreover, RT-qPCR showed that MSRV was present in all 9 tested tissues of infected fish, and the virus loads of the spleen and heart were significantly higher than that in other tissues tested. In conclusion, we isolated and identified a new MSRV strain from diseased largemouth bass, and our results will provide new material and information for the prevention and control strategy for MSRV. • A new MSRV strain (MSRV-NY01) was isolated from diseased largemouth bass. • Two new sensitive cell lines of MSRV were found. • A detailed replication kinetics of MSRV-NY01 in GS cell was determined. • Tissue distribution of MSRV-NY01 was investigated. • The MSRV-NY01 strain was significantly virulent to largemouth bass juvenile. [ABSTRACT FROM AUTHOR]

Background: Platinum-based chemotherapy is one of the most common treatments for many cancers; however, the effect of chemotherapy varies from individual to individual. Excision repair cross complementation group 1 (ERCC1) is widely recognized as a key gene regulating nucleotide excision repair (NER) and is closely associated with platinum response. Many studies have yielded conflicting results regarding whether ERCC1 polymorphisms can affect the response to platinum and overall survival (OS). Therefore, it is necessary to perform a meta-analysis of patients with specific races and cancer types., Methods: Eight databases (EMBASE, PubMed, Cochrane Library, Chinese National Knowledge Infrastructure, Scopus, VIP, China Biology Medicine disc and Wanfang databases) were searched. Results were expressed in terms of odds ratios (ORs), hazard ratios (HRs) and 95% CIs., Results: In this study, rs11615, rs2298881 and rs3212986 SNPs were studied. In the comparison between CT and TT on the response to platinum, esophageal cancer [I2 = 0%, OR = 6.18, 95% CI(1.89,20.23), P = 0.003] and ovarian cancer [I2 = 0%, OR = 4.94, 95% CI(2.21,11.04), P<0.001] showed that the rs11615 CT genotype predicted a better response. In the comparison between CC and TT, ovarian cancer [I2 = 48.0%, OR = 6.15, 95% CI (2.56,14.29), P<0.001] indicated that the CC genotype predicted a better response. In the meta-analysis of OS, the CC genotype was related to longer OS than TT in ovarian cancer [TT vs CC: I2 = 57.7%, HR = 1.71, 95% CI (1.18, 2.49), P<0.001]., Conclusion: The ERCC1 rs11615 polymorphism was related to the response to platinum and OS, but the correlation is based on specific cancer types in the Asian population., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2023 Wu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)