1. Two new sesquiterpenoid glycoside compounds from the calyces of Physalis alkekengi L. var. franchetii (Mast.) Makino.
- Author
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Teng, Yang, Zhang, Xiang-Rong, Li, Xiao-Lei, Gao, Jia, Ni, Lei, and Zhan, Guan-Qun
- Subjects
STEROIDS ,ANTI-inflammatory agents ,ALKALOIDS ,HYDROCARBONS ,BIPHENYL compounds ,ENZYME inhibitors ,FLAVONOIDS ,TERPENES ,PLANT extracts ,FLOWERS ,ANTI-infective agents ,GLYCOSIDES ,MOLECULAR structure ,PHENOLS ,ANTIOXIDANTS ,GLYCOSIDASES - Abstract
Two new sesquiterpenoid glycosides, 8α (H)-eudesmane-1,3,11 (13)-triene-2-one -12-O-β-D-glucopyranoside (1) and dmetelisproside B (2), together with ten known compounds (3–12) were isolated from calyces of Physalis alkekengi L. var. franchetii (Mast.) Makino (PAF). Their structures were unambiguously elucidated through HR-ESI-MS, UV, IR, and NMR spectral data. Compounds 1, 10, and 12 exhibited DPPH scavenging ability with IC
50 values of 33.69 ± 6.65, 6.29 ± 0.06, and 25.66 ± 3.06 μM, respectively. Additionally, 10 and 12 demonstrated weak α-glucosidase inhibition activity with IC50 values of 250.9 ± 6.60 and 347.6 ± 2.48 μM, respectively. [ABSTRACT FROM AUTHOR]- Published
- 2024
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