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Tourism experiences bring about physical or psychological feelings in tourists, which can not only leave tourists with deep memories, but also affect their behavioral intentions. Tourism experiences are meaningful only if they can be remembered and influence word of mouth and decision making. A better understanding of what influences tourism experience memory will help optimize the supply and further development of tourism destinations. This study explores the antecedents of rural tourism experience memory from the tourism supply perspective, revealing the mechanism of effect of these antecedents on tourists' tourism experience memory formation through a questionnaire-based survey of 556 participants in Xidi Village, China, and correlation and multiple regression analyses. The results show that perceptions about the supply of rural tourism destinations trigger positive emotions that, in turn, affect the formation of rural tourism experience memory. Through the mediating role of positive emotions, there is a significant correlation between perception of rural tourism destination supply and the formation of rural tourism experience memories. [ABSTRACT FROM AUTHOR]

Aims Anaplastic lymphoma kinase ( ALK)-rearranged renal cell carcinoma ( RCC) is a rare subtype of RCC reported in recent years, with eight cases so far. The aims of the present study were to screen ALK-rearranged cases from a large cohort of RCCs in China to determine the frequency of ALK rearrangement and investigate the clinicopathological features and outcomes. Methods and results Tissues from a total of 477 RCC patients in China were embedded into tissue microarrays for immunostaining. Fluorescence in-situ hybridization ( FISH) and fluorescence quantitative reverse transcription polymerase chain reaction ( RT- PCR) were applied to identify and confirm the rearrangement of ALK, and to identify the genes fused with ALK. ALK expression was identified in two of 477 RCCs. By FISH analysis, the two tumours showed either a 1R1G1F or a 2R2G signal pattern, indicating rearrangement involving ALK. Fluorescence quantitative RT- PCR detected the TPM3- ALK fusion and EML4- ALK fusion transcripts in the two tumours, respectively. Follow-up data were analyzed for the two cases and eight other ALK-rearranged RCCs reported in the literature. Two patients died from RCCs, on the 16th month and 48th month after surgery, respectively. The 5-year cancer-specific survival rate of patients with the 10 ALK-rearranged RCCs was lower than that of patients with International Society of Urological Pathology (ISUP) G1, G2 and G3 clear cell RCC ( CCRCC) and papillary RCC ( PRCC), but higher than that of patients with G4 CCRCC and PRCC. Conclusions ALK-rearranged RCC is a rare subtype of adult RCC and is associated with distinct histological features and a poor prognosis. Identification of ALK-rearranged RCC has important clinical significance, because patients might benefit from ALK inhibitor therapy as used in lung adenocarcinoma. [ABSTRACT FROM AUTHOR]

Background: Tourism eco-efficiency is a performance basis for evaluating green total factor productivity and sustainable development., Objective: The objective of this study was to measure tourism eco-efficiency in Inner Mongolia and explore its influencing factors. The aim was to provide an accurate reference for improving the quality and efficiency of tourism in Inner Mongolia and promoting the sustainable development of the regional economy and society., Methods: Tourism eco-efficiency in Inner Mongolia from 2009 to 2019 was calculated using a super-slacks-based measure (SBM) model with an undesirable output. The spatial variation function was used to explore the spatial evolution pattern of tourism eco-efficiency in Inner Mongolia, and the influencing factors of the spatial evolution were analyzed by geographically weighted regression., Results: Tourism eco-efficiency in Inner Mongolia is relatively low. Eco-efficiency values among cities in Inner Mongolia vary, and their distribution is not balanced. The structural eco-efficiency of tourism in Inner Mongolia has been consistent from 2009 to 2019. The degree of homogenization in the overall direction is relatively good. Furthermore, its spatial distribution form and internal structure evolution show a certain regularity and continuity. The pattern evolution of tourism eco-efficiency in Inner Mongolia is jointly driven by the economic level, environmental regulation, industrial structure, traffic conditions, resource endowment, and tourism reception facilities. These influencing factors show obvious spatial heterogeneity., Conclusion: From the perspective of Inner Mongolia, the difference in the tourism eco-efficiency value from 2009 to 2019 was relatively large, but the number of effective areas in the efficiency frontier generally showed a fluctuating growth trend. The range parameters of tourism eco-efficiency showed a decreasing trend, and the spatial correlation effect of tourism eco-efficiency in Inner Mongolia showed a decreasing trend under the influence of structural and spatial differentiation., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Wang and Wu.)

This study explores the spatial structure of regional tourism cooperation networks among 27 cities in the Yangtze River Delta from the perspective of supply and demand. Data from the supply network were collected from official news released by the Chinese government and quotations for tour routes published by travel agencies. Travel notes published on tourists' blog community platforms about their travel experiences were used as source data for the demand network. The degree of cooperation between the cities was analyzed based on the frequency of occurrence and co-occurrence of information on tourist attractions or cities in the Yangtze River Delta region in tourist notes, tourist route quotes, and official news. This study divides 27 cities in the Yangtze River Delta region into three categories: those where supply matches demand (e.g., Shanghai and Nanjing), nine cities where there is a demand lag (e.g., Zhenjiang), and 16 cities where there is a supply lag (e.g., Wuxi). Investigating the differences between the supply and demand networks is helpful to understand the effectiveness of regional tourism cooperation mechanisms and government policies, which is crucial for the sustainability and good governance of regional tourism., Competing Interests: The authors have declared that no competing interests exist.

Triclocarban (TCC) has a high detection frequency in soil, rivers, sediments, and organisms, and its ecological risks have attracted substantial attention. In this study, we analyzed the fate of TCC in four wastewater treatment plants (WWTPs) in Zhengzhou, China, the biodegradation characteristics during the composting process, and the ecological risks of TCC when entering different environmental compartments. The concentration of TCC in the influent was 731.1-812.4 ng/L. More than 53.4% of TCC was biodegraded during the wastewater treatment process, and less than 2.5% was retained in the effluent. TCC was effectively removed through microbial degradation and sewage sludge absorption, and there were only minor differences in the different wastewater treatment processes. It is worth noting that more than 38% of TCC was enriched in sewage sludge (1430.1-1663.8 ng/g). The corresponding biodegradation rates of TCC were 65.7% and 82.8% in sewage sludge after 17 days of composting treatment with sawdust and straw as bulking agents, respectively. The estimated results showed that effluent discharge into the city rivers was safe. Composting could effectively degrade TCC and decrease the ecological risk of TCC when applied to sewage sludge., (Copyright © 2021 Elsevier B.V. All rights reserved.)

Triclosan (TCS) is widely used as an antibacterial disinfectant in personal care products, especially in rapidly-urbanizing countries, such as China. Almost all TCS enters wastewater treatment plants (WWTPs), but the fate of the TCS in the WWTPs is unclear. TCS may be present in sewage sludge or in effluent, and the discharge of TCS into an ecosystem can pose environmental risks. In the present study, influent, effluent, and sewage sludge were collected from four typical urban WWTPs, and the fate of TCS in the plants was investigated. The study was conducted in Zhengzhou, a city in the middle reaches of the Yellow River in China. The sewage sludge was used for aerobic composting to study the influences of different ventilation treatments on the biodegradation effects of TCS and the changes in the microbial community during the composting process. The results showed that the mean concentration of TCS in the influent of the four typical WWTPs was 397.1 ng/L. The mean level of TCS in the effluent was 8.0 ng/L. The mean concentration of TCS in the sewage sludge was 814.4 ng/g. For the four WWTPs, the percentages of TCS removal were 97.6% (Nansanhuan), 97.6% (Xinzheng), 98.8% (Wulongkou), and 97.9% (Chenyu), respectively. The sewage sludge enrichment rates for TCS ranged between 36.4% and 49%. Therefore, there is a need to focus on the environmental risks from sewage sludge. During aerobic composting, the TCS was effectively degraded under three ventilation strategies. Thus, improved ventilation could enhance the degradation rate of TCS. Moreover, TCS degradation occurred in the mesophilic period and in the early stage of the thermophilic phase period. Finally, the degradation rates of TCS in sewage sludge samples composted with low-, medium-, and high-ventilation treatments were 48.1%, 59.0%, and 59.5%, respectively. Thus, high ventilation could provide enough oxygen for the pile and enhanced microorganism activity, benefiting the degradation of TCS. In addition, the microbial communities change during the composting process, and a diversity index of the changes can help explain the composting process., (Copyright © 2019 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Volatile organic compounds (VOCs) are the major components of the odor emitted from sewage sludge composting plants and are generally associated with odorous nuisances and health risks. However, few studies have considered the potential ozone generation caused by VOCs emitted from sewage sludge composting plants. This study investigated the VOC emissions from a full-scale composting plant. Five major treatment units of the composting plant were chosen as the monitoring locations, including the dewatered room, dewatered sludge, blender room, fermentation workshop, and product units. The fermentation workshop units displayed the highest concentration of VOC emissions at 2595.7 ± 1367.3 μg.m -3 , followed by the blender room, product, dewatered sludge, and dewatered room units, whose emissions ranged from 142.2 ± 86.8 μg.m -3 to 2107.6 ± 1045.6 μg.m -3 . The detected VOC families included oxygenated compounds, alkanes, alkenes, sulfide compounds, halogenated compounds, and aromatic compounds. Oxygenated compounds, particularly acetone, were the most abundant compounds in all samples. Principal component analysis revealed that the dewatered room and dewatered sludge units clustered closely, as indicated by their similar component emissions. The product units differed from the other sampling units, as their typical compounds were methanethiol, styrene, carbon disulfide, and hexane, all of which were the products of the latter stages of composting. Among the treatment units, the fermentation workshop units had the highest propylene equivalent (propy-equiv) concentration. Dimethyl disulfide and limonene were the major contributors. Limonene had the highest propy-equiv concentration, which contributed to the increased atmospheric reactivity and ozone formation potential in the surrounding air. To control the secondary environmental pollution caused by the VOC emissions during sewage sludge composting, the emission of limonene and dimethyl disulfide must be controlled from the blender room and fermentation workshop units., (Copyright © 2018 Elsevier B.V. All rights reserved.)