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Guided by the Transtheoretical Model (Prochaska & DiClemente, 1982), this study investigated the differences of physical activity levels and correlates (i.e., self-efficacy, decisional balance, process of change) across different stages of change levels among Chinese college students. The relationships between students' physical activity correlates and physical activity behavior was also examined. The participants were 887 college students (365 males; M[subscript age] = 20.51, SD = ± 1.67) recruited from four universities in south and south-canter China. Participants completed a battery of established questionnaires assessing their physical activity correlates (self-efficacy, decisional balance, process of change) and 1-week physical activity levels. Results suggested that Chinese college students in the high stage of change group reported significantly higher physical activity levels and correlates than those in the low stage of change group. Pearson correlation analyses suggested that students' self-efficacy was moderately related to other correlates and physical activity behavior. Yet, decisional balance and process of change were only modestly associated with physical activity levels for both groups. Regression analyses further revealed students' self-efficacy emerged as the only significant contributor of their daily PA levels across the two groups. However, decision balance and process of change failed to predict physical activity levels. The implications for practice and direction of future research were discussed.

Objective: The constant deterioration of the physical fitness of college students has been a popular topic in China, thus this research analyzes the potential health risk of inadequate physical activity among college students. Participants/methods: During the national student fitness test (NSFT) in 2012, 1500 students from Tsinghua University were recruited and asked to complete the international physical activity questionnaire. Finally, 1414 (94.3%) students completed the study. Results/conclusions: Compared with those students who actively participate in exercise, the risk of obesity in college students lacking exercise was 1.25 times higher. Likewise, the probability of failure in the grip strength test and the standing long jump was also higher, with increases of 2.39 fold and 1.39 fold, respectively. Moreover, the total score of physical fitness test was the same. Consequently, this study suggests that college students should exercise regularly to increase their physical fitness.

Aims: Lakeshore wetlands are global carbon (C) hotspots, but their role in C sequestration has been largely overlooked. The rhizosphere has a complex interaction of microbiota and metabolites, which plays an important role in wetland C cycling. This study aims to understand how the rhizospheric interactions affect harvested aboveground C and soil C of lakeshore wetlands in a subtropical region. Methods: An investigation of five lakeshore reed (Phragmites australis) wetlands at the similar latitudes of the Lower Yangtse Valley in China was carried out to explore the relationship of rhizospheric interactions with harvested aboveground C and soil C. The plant traits and soil physicochemical properties were determined due to their important role in affecting rhizosphere interactions. Results: Plant traits and soil physicochemical properties significantly differed among the sites, while aboveground C fixation did not significantly differ. The soil organic C (SOC) content of the topsoil was accounting for the majority of the soil total C at most sites, except for the wetland at the Yangtze River estuary with higher soil pH and conductivity, whose soil inorganic C (SIC) accounted for almost half. Bacterial community and metabolite composition were significantly partitioned across the region. Structural equation modeling revealed the rhizospheric interactions positively affected aboveground C and SOC, but negatively affected SIC. Their effects on soil C content were stronger than those on aboveground C fixation. Conclusions: The rhizosphere exhibited the direct and indirect effects on harvested aboveground C and soil C by altering microbial community structure and metabolite composition. [ABSTRACT FROM AUTHOR]

Perfluorooctanoic acid (PFOA) belongs to the class of persistent organic pollutants widely distributed in the environment, and has the characteristics of high bioaccumulation and refractory degradation in organisms. To date, there are limited reports on the microbial degradation of PFOA. In this pursuit, the present study envisaged the screening of microbes capable of degrading PFOA from the soils of eight sites in Huaxi district of Guizhou province, China, using the enrichment culture. Sixteen bacterial isolates were obtained in total, and their growth curves were found to be unimodal or bimodal in PFOA-spiked MSM cultural solutions. Five isolates of them, viz. 4-a, 5-b, 6-a, 7-c and 8-a, were further selected for in-depth study of PFOA degradation, and it was found that all of isolates could increase the concentrations of fluoride ions in the cultural solutions. The five PFOA-degrading bacteria were identified as Pseudomonas sp. Obtained Pseudomonas resources would contribute to the studies on the degradation of PFOA by the facultative anaerobes. [ABSTRACT FROM AUTHOR]

Objectives: Thalassemia, the most common global monogenetic disorder, is highly prevalent in southern China. Epidemiological and molecular characterization of thalassemia is important for designing appropriate prevention strategies in high-risk areas, especially the border area of Guangxi-Yunnan-Guizhou province in southwestern China. Methods: We recruited 38812 reproductive age couples and screened them for thalassemia. Routine blood tests as well as hemoglobin components and levels were evaluated. In addition, suspected thalassemia were identified by gap polymerase chain reaction (Gap-PCR) and PCR-based reverse dot blot (PCR-RDB). Results: The overall prevalence of thalassemia was 26.76%. Specifically, incidences of α-thalassemia, β-thalassemia, and concurrent α- and β-thalassemia were 17.52%, 6.92%, and 2.32%, respectively. The diagnosed α-thalassemia anomalies were associated with six gene mutations and 25 genotypes. The β-thalassemia anomalies were associated with 12 gene mutations and 15 genotypes. Moreover, among the 1799 concurrent mutated α- and β-thalassemia genes, 95 different genotypes were identified. Couples in which both partners were positive for α-thalassemia and β-thalassemia isotypes were 8.80% and 2.08%, respectively. The proportion of couples at a risk of having children with thalassemia major or intermedia was high. Conclusions: This study elucidates on the prevalence and molecular characterization of thalassemia in the border area of Guangxi-Yunnan-Guizhou provinces. These findings provide valuable baseline data for genetic counseling and prenatal diagnosis, with the overarching goal of preventing and controlling severe thalassemia. [ABSTRACT FROM AUTHOR]

Brassica juncea is one of a unique vegetable in China, its tumorous stem can be processed into pickle or as fresh vegetable. For a long time, early-bolting as a main factor affects yield and quality of B. juncea, which happens about 15% all year round. As plant specific blue light receptors, FKF1/LKP2 involved in photoperiod flowering. To analyze the expression levels of BjuFKF1/BjuLKP2 and screen their interaction proteins in B. juncea, qRT-PCR and yeast two hybrid assays were recruited. qRT-PCR assays found that the expression levels of BjuFKF1 and BjuLKP2 were up-regulated expressed under both white and blue light. When under different light, BjuFKF1 was significantly increased at vegetative growth stage, but decreased in flowers under blue light. For BjuLKP2, its expression levels did not show significant changes under different light treatment. To investigate interaction proteins, BjuFKF1 and BjuLKP2 were used as bait proteins, and nine potential proteins were screened from yeast library. Yeast two hybrid assays was recruited to further verify their interaction, the results showed that both BjuFKF1 and BjuLKP2 interacted with BjuCOL, BjuCOL3, BjuCOL5, BjuAP2, BjuAP2-1 and BjuSKP1f, only BjuLKP2 interacted with BjuSVP-1 and BjuCDF1 in vivo. In this study, BjuFKF1 and BjuLKP2 were up-regulated expressed under both white and blue light. Yeast two hybrid results verified that BjuFKF1 and BjuLKP2 interacted with six and eight of those nine proteins in vivo, respectively. All of those results will provided reference genes to study BjuFKF1/BjuLKP2 regulated flowering pathway in B. juncea. [ABSTRACT FROM AUTHOR]

Background: Although glucose‐6‐phosphate dehydrogenase (G6PD) deficiency is the most common inherited disorder in the Chinese population, there is scarce evidence regarding the epidemiology, evolutionary origin, and malaria‐induced positive selection effects of G6PD‐deficient alleles in various Chinese ethnic populations. Methods: We performed a large population‐based screening (n = 15,690) to examine the impact of selection on human nucleotide diversity and to infer the evolutionary history of the most common deficiency alleles in Chinese populations. Results: The frequencies of G6PD deficiency ranged from 0% to 11.6% in 12 Chinese ethnic populations. A frequency map based on geographic information showed that G6PD deficiency was highly correlated with historical malaria prevalence in China and was affected by altitude and latitude. The five most frequently occurring G6PD gene variants were NM_001042351.3:c.1376G>T, NM_001042351.3:c.1388G>A, NM_001042351.3:c.95A>G, NM_001042351.3:c.1311T>C, and NM_001042351.3:c.1024C>T, which were distributed with ethnic features. A pathogenic but rarely reported variant site (NM_001042351.3:c.448G>A) was identified in this study. Bioinformatic analysis revealed a strong and recent positive selection targeting the NM_001042351.3:c.1376G>T allele that originated in the past 3125 to 3750 years and another selection targeting the NM_001042351.3:c.1388G>A allele that originated in the past 5000 to 6000 years. Additionally, both alleles originated from a single ancestor. Conclusion: These results indicate that malaria has had a major impact on the Chinese genome since the introduction of rice agriculture. [ABSTRACT FROM AUTHOR]

Refracturing is an encouraging way to uplift gas flow rate and ultimate gas recovery from shale gas wells. A numerical model, considering the stimulated reservoir volume and multiscale gas transport, is applied to simulate the gas production from a refractured shale gas well. The model is verified against field data from a shale gas reservoir in Sichuan Basin. Two refracturing scenarios: refracturing through existing perforation clusters and refracturing through new perforation zones, are included in the simulation work. Three years after production is determined to be the optimum time for refracturing based on the evolution analysis of reservoir pressure, effective stress, fracture permeability, and gas recovery. The role that the hydraulic fracture conductivity and hydraulic fracture half-length play in gas production for different refracturing cases is explored. Pumping parameters of the refracturing job in Sichuan Basin are discussed combining with sensitivity analysis, and suggestions for pumping parameters optimization are proposed. [ABSTRACT FROM AUTHOR]

Objective:Risk factors for chronic suppurative otitis media (CSOM) were not clearly established. The study was to investigate the etiological factors for CSOM from a population of Han adults in China. Methods:A case-control study was conducted at Second Affiliated Hospital of Xi’an Jiaotong University, School of Medicine in China. A total of 416 individuals participated in this study, which included 206 cases and 210 controls. Results:Multivariate logistic regression analysis revealed male (OR = 0.42; 95% CI: 0.21–0.83), BMI increasing (OR = 0.85; 95% CI: 0.77–0.93), URTI (OR = 152.85; 95% CI: 34.11–684.93), smoke/passive smoke (OR = 7.11; 95% CI: 3.36–15.07), residential location (urban area) (OR = 0.27; 95% CI: 0.13–0.56), serum calcium increasing (OR = 0.09; 95% CI: 0.01–0.71) were prime risk factors for CSOM. Univariate analysis revealed that low socioeconomic status (OR= 2.33; 95% CI: 1.57–3.45) and hepatitis B (OR = 4.90; 95% CI: 1.82–13.21) were risk factors together with the above variables. Conclusion:This study has identified several variables as risk factors for CSOM, suggesting better healthcare, living condition, as well as better nutrition might decrease the development of CSOM. Further studies are necessary to assess the outcome of CSOM after interventions in the etiological factors. [ABSTRACT FROM PUBLISHER]

This study examines China's equity-for-debt swap programme by a detailed case study of the reform process in one state-owned enterprise. We examine the extent to which Asset Management Companies (AMCs) have been able to exercise their ownership rights in the state-owned enterprise as well as related reforms to wage structure, managerial appointments and separation of social welfare responsibilities are examined. The main finding is that the AMCs have been unable to exercise their bundle of ownership rights. On the basis of this finding it is suggested that it is going to take ranch longer for the Chinese government to realize its objectives compared with many previous debt-workout programmes such as Savings and Loans reform in the USA. [ABSTRACT FROM AUTHOR]

Background: The local diet in high-poverty areas in China is mainly vegetarian, and children may be more vulnerable to vitamin B12 deficiency.Objective: The aims of this study were to explore the vitamin B12 status of toddlers living in high-poverty areas of China and to observe the effects of different complementary foods on the vitamin B12 status and cognitive level of these toddlers.Methods: The study was nested within a cluster-randomized controlled trial implemented in 60 administrative villages (clusters) of Xichou County in which infants aged 6 months old were randomized to receive 50 g/d of pork (meat group), an equi-caloric fortified cereal supplement (fortified cereal group) or local cereal supplement (local cereal group) for one year. At 18 months, a subsample of the 180 toddlers (60 from each group) was randomly tested for serum vitamin B12 and total homocysteine (tHcy) levels, and their neurodevelopment was evaluated.Results: The median serum concentrations of vitamin B12 and tHcy were 360.0 pg/mL and 8.2 μmol/L, respectively, in children aged 18 months. Serum vitamin B12 concentrations less than 300 pg/mL were found in 62 (34.4%) children, and concentrations less than 200 pg/mL were found in 30 (16.7%) children. The median vitamin B12 concentration was significantly different among the three groups (P < 0.001). The highest vitamin B12 level was demonstrated in the fortified cereal group (509.5 pg/mL), followed by the meat group (338.0 pg/mL) and the local cereal group (241.0 pg/mL). Vitamin B12 concentration was positively correlated with the cognitive score (P < 0.001) and the fine motor score (P = 0.023) of the Bayley Scales of Infant Development, 3rd Edition (BSID III) screening test. Compared to the local cereal group, children in the meat group had higher cognitive scores (P < 0.05).Conclusion: In poor rural areas of China, vitamin B12 deficiency in toddlers was common due to low dietary vitamin B12 intake. Fortified cereal and meat could help improve the vitamin B12 status of children and might improve their cognitive levels.Trial Registration: The larger trial in which this study was nested was registered at clinical trials.gov as NCT00726102 . It was registered on July 31, 2008. [ABSTRACT FROM AUTHOR]

Aims: Asthenozoospermia is the most common factor of male infertility, mainly caused by multiple morphological abnormalities of the sperm flagella (MMAF) and primary ciliary dyskinesia (PCD). Previous studies have shown that genetic factors may contribute to MMAF and PCD. The study aimed to identify novel potentially pathogenic gene mutations in a Chinese infertile man with MMAF and PCD-like phenotypes. Methods: A Chinese infertile man with MMAF and PCD was enrolled in this study. Whole exome sequencing and Sanger sequencing were performed to identify potential causative genes and mutations. Results: A novel homozygous missense mutation (c.1450G>A; p.E484K) of CCDC40 was finally identified and Sanger sequencing confirmed that the patient carried the homozygous mutation, which was inherited from his parents. We reported the first homozygous missense CCDC40 mutation in infertile men with MMAF but had other milder PCD symptoms. Conclusion: Our findings not only broaden the disease-causing mutation spectrum of CCDC40 but also provide new insight into the correlation between CCDC40 mutations and MMAF.

Background: Thalassemia is an extremely prevalent monogenic inherited blood disorder in southern China. It is important to comprehensively understand the molecular spectrum of thalassemia in an area with such a high prevalence of thalassemia before taking appropriate actions for the prevention and treatment of this disorder. Herein, we explored the clinical feasibility of using next-generation sequencing (NGS) for large-scale population screening to illustrate the prevalence and spectrum of thalassemia in Southern Jiangxi., Methods: Blood samples collected from 136,312 residents of reproductive age in Southern Jiangxi were characterized for thalassemia by NGS. A retrospective analysis was then conducted on blood samples determined to be positive for thalassemia., Results: In total, 19,827 (14.545%) subjects were diagnosed as thalassemia carriers, and the thalassemia prevalence rate significantly varied by geographical region (p < 0.001). A total of 40 α-thalassemia genotypes including 21 rare genotypes were identified, with -@- SEA /αα being the most prevalent genotype. 42 β-thalassemia genotypes including 27 rare genotypes were identified, with the most common mutation IVS II-654 C > T accounting for 35.257% of these β-thalassemia genotypes. Furthermore, 74 genotypes were identified among 608 individuals with combined α- and β-thalassemia. Notably, most individuals with rare thalassemia mutations had mildly abnormal hematologic parameters including microcytic hypochromia., Conclusions: Our findings demonstrate the great heterogeneity and diverse spectrum of thalassemia in Southern Jiangxi, emphasizing the importance and necessity of persistent prevention and control of thalassemia in this region. Additionally, our findings further suggest that NGS can effectively identify rare mutations and reduce the misdiagnosis rate of thalassemia., (© 2023. BioMed Central Ltd., part of Springer Nature.)

In the process of China's economic transformation, enterprises urgently need to use green innovation networks to realize corporate sustainability. Based on resource-based theory, this study explores the internal mechanism and boundary conditions of green innovation network embeddedness that affect corporate environmental responsibility. This paper conducts an empirical study based on panel data of listed companies engaged in green innovation in China from 2010 to 2020. Drawing on network embeddedness theory and resource-based theory, we found that relational and structural embeddedness influenced green reputation, which affected corporate environmental responsibility. We also identified the importance of ethical leadership and examined its role in moderating the effect of green innovation network embeddedness. A further investigation revealed that the impact of network embeddedness on corporate environmental responsibility was particularly pronounced in the samples of enterprises with high-level political ties, loose financing restrictions, and nonstate ownership. Our findings highlight the advantages of embedded green innovation networks and offer theoretical references and recommendations for enterprises considering network participation. Enterprises should attach great importance to the network embedding strategy of green innovation for corporate environmental responsibility and actively integrate the concept of green development into network relationship embedding and network structure embedding. Moreover, the relevant government department should provide necessary environment incentive policies according to the enterprise's development needs, especially for the enterprises with low-level political ties, high financing restrictions, and state ownership.

Multiple morphological abnormalities of the sperm flagellum (MMAF) have been reported to be an important cause of male infertility and reflect a heterogeneous genetic disorder. Previous studies have identified dozens of candidate pathogenic genes for MMAF, but the aetiology in approximately 50% of cases remains unexplained. The present study aimed to identify novel potentially pathogenic gene variants of MMAF. A Chinese family with a 32-year-old infertile proband presenting with MMAF was recruited, and sperm morphology of the patient was examined by Papanicolaou staining. Whole exome sequencing was performed on the proband and Sanger sequencing was used to identify genetic variants in the family. The frequencies of variants were assessed using public databases and the effects on protein structure and function were predicted by online bioinformatics tools. The patient exhibited asthenozoospermia and a MMAF phenotype. Novel compound heterozygous variants (c.5368C > T, p.R1790C and c.13183C > T, p.R4395W) of the DNAH17 gene were identified in the patient, and showed autosomal recessive inheritance in this family. These variants were very rare in the GnomAD database. The two mutated amino acids were located in a highly conserved region of the DNAH17 protein. In silico analysis revealed that the compound heterozygous variants may compromise the function of DNAH17. Our findings expand upon the spectrum of pathogenic DNAH17 variants that are responsible for MMAF, and provide new knowledge for genetic counselling of male infertility due to MMAF., (© 2022 Wiley-VCH GmbH.)

Background: Epilepsy is one of the most common neurological problems among children. The aim of this survey was to assess the knowledge and attitude among preschool staff in Shanghai regarding epilepsy., Methods: A cross-sectional survey was carried out among the staff at selected preschools. A stratified random sampling method was first used to identify suitable subjects. Data were obtained using a self-completed questionnaire. A standardized collection of demographic information was performed, and participants were given a questionnaire about their knowledge and attitudes regarding epilepsy., Results: A total of 1069 subjects completed the questionnaire. In this survey, 387 (36.2%) staff members had previously participated in related training. 17.6% of teachers knew how to provide appropriate first aid for seizures. Correct responses regarding first aid for seizures, such as laying the person on his or her side (24.9%), moving harmful objects out of the way (20.7%), protecting the head (36.1%), waiting until the seizure ends (7.9%), and dialing the emergency number (40.1%), were low. The staff members had different attitudes towards children with epilepsy: some subjects had a positive attitude, some had a negative attitude., Conclusions: The level of first-aid knowledge among preschool staff in Shanghai relevant to epilepsy was low. There is an urgent need to educate staff about epilepsy and appropriate first-aid practices for seizures.

Fluxes of methane (CH 4 ) and nitrous oxide (N 2 O) from two rice varieties, Huayou 14 and Hanyou 8, were monitored using closed chamber/gas chromatography method. Huayou 14 is a commonly grown variety of rice whereas Hanyou 8 is a water-saving and drought-resistant rice (WDR) variety. Low soil volumetric water content (VWC) existed in the treatments on the slope (W5 < W4 < W3 < W2). On the slope, rice yields of Hanyou 8 decreased by 12-39%, and Huayou 14 by 11-46% as compared to the plots on the flat. The total compatible solutes in Hanyou 8 had a greater variational range than Huayou 14. Compared to W1, CH 4 emissions from W2-W5 decreased by 58-86% in Hanyou 8 and 38-86% in Huayou 14, whereas those of N 2 O increased by 26-121% in Hanyou 8 and 49-189% in Huayou 14 across both two seasons, which was mainly because the VWC varied in W2-W5 treatment. Under the treatments in the slope (W2, W3, W4, and W5), the global warming potential (GWP) was dominated by N 2 O emissions, which accounted for 69-90% of the GWP. Hanyou 8 had greater tolerance for water stress than Huayou 14 did, as evident from the smaller reductions in rice yield and greater variational range of total compatible solutes content. Water stress could reduce CH 4 emissions but decrease N 2 O emissions for both rice varieties. This results suggest that planting WDR varieties under water shortage irrigation (such as W4, W5) will be able to maintain rice yields and reduce the GWP with less water.

Background: The local diet in high-poverty areas in China is mainly vegetarian, and children may be more vulnerable to vitamin B 12 deficiency., Objective: The aims of this study were to explore the vitamin B 12 status of toddlers living in high-poverty areas of China and to observe the effects of different complementary foods on the vitamin B 12 status and cognitive level of these toddlers., Methods: The study was nested within a cluster-randomized controlled trial implemented in 60 administrative villages (clusters) of Xichou County in which infants aged 6 months old were randomized to receive 50 g/d of pork (meat group), an equi-caloric fortified cereal supplement (fortified cereal group) or local cereal supplement (local cereal group) for one year. At 18 months, a subsample of the 180 toddlers (60 from each group) was randomly tested for serum vitamin B 12 and total homocysteine (tHcy) levels, and their neurodevelopment was evaluated., Results: The median serum concentrations of vitamin B 12 and tHcy were 360.0 pg/mL and 8.2 μmol/L, respectively, in children aged 18 months. Serum vitamin B 12 concentrations less than 300 pg/mL were found in 62 (34.4%) children, and concentrations less than 200 pg/mL were found in 30 (16.7%) children. The median vitamin B 12 concentration was significantly different among the three groups (P < 0.001). The highest vitamin B 12 level was demonstrated in the fortified cereal group (509.5 pg/mL), followed by the meat group (338.0 pg/mL) and the local cereal group (241.0 pg/mL). Vitamin B 12 concentration was positively correlated with the cognitive score (P < 0.001) and the fine motor score (P = 0.023) of the Bayley Scales of Infant Development, 3rd Edition (BSID III) screening test. Compared to the local cereal group, children in the meat group had higher cognitive scores (P < 0.05)., Conclusion: In poor rural areas of China, vitamin B 12 deficiency in toddlers was common due to low dietary vitamin B 12 intake. Fortified cereal and meat could help improve the vitamin B 12 status of children and might improve their cognitive levels., Trial Registration: The larger trial in which this study was nested was registered at clinical trials.gov as NCT00726102 . It was registered on July 31, 2008.

Purpose : To better promote college students' physical activity (PA) and quality of life (QoL), it is imperative to understand this population's PA correlates, such as self-determined motivation and perceived competence. However, few studies existed in this area of inquiry among Chinese college students. Thus, the purpose of this study was to examine the relationships among Chinese college students' self-determined motivation, PA, and QoL. Method: A total of 220 college students (115 females; M age = 20.29 years, SD = 2.37; M BMI = 20.67) were recruited from one university in south-central China. Participants were instructed to wear the ActiGraph GT9X Link (ActiGraph, Pensacola, FL, USA) accelerometers for 7 days. A minute-by-minute stepping rate methodology was used to determine participants sedentary behaviors, light physical activity (LPA) and moderate-to-vigorous physical activity (MVPA). Participants' self-determined motivation (autonomous, controlled, and amotivation), perceived competence, and QoL (physical function, stress, depression, fatigue, sleep, and social issues) were assessed by a battery of validated surveys in June 2017. Results : Participants reported moderate-high levels of PA correlates and QoL as the means ranged from 5.5 to 6 (out of 7) for PA correlates and 2.75 to 4 (out of 4) for QoL. The minute-by-minute stepping rate revealed participants had average 580.51 min/day in sedentary, 134.77 min/day in LPA, and 1.57 min/day in MVPA. Regression analyses for physical function, stress, depression, and social issues suggested that the models explained 4%-8% of the variances. Specifically, perceived competence was the negative predictor of the problems with physical function (β = -0.17, p < 0.05) and depression (β = -0.18, p < 0.01), amotivation was positively associated with depression and stress ( p < 0.05). Additionally, controlled motivation predicted the ability to participate in social roles and activities (β = 0.22, p < 0.05). No significant predictors emerged for fatigue or for sleep. Conclusions : Findings suggest Chinese college students' perceived competence and social support are critical for improving PA and QoL. In addition, strategies are needed to motivate Chinese college students to engage in PA participation and improve overall well-being.

Objective: To assess the association of polymorphisms of rs3819024 and rs8193037 loci in the promoter region of IL-17A gene with the risk of ischemic stroke (IS) among ethnic Han Chinese from Guangxi., Methods: The polymorphisms of rs3819024 and rs8193037 loci were detected by a SNaPshot assay and DNA sequencing among 392 IS patients and 443 healthy controls with matched age and gender., Results: The genotypes, dominant model, recessive model, and alleles of rs3819024 polymorphisms showed no significant difference between the two groups, with the P values calculated as 0.150, 0.227, 0.125, 0.594 and 0.202, respectively, and OR (95% CI) as 1.27(0.92-1.74), 1.28(0.86-1.91), 1.27(0.94-1.72), 1.10(0.78-1.54), and 1.13(0.94-1.38), respectively. The genotypes, dominant model, recessive model, and alleles of rs8193037 polymorphisms also showed no significant difference between the two groups, with the P values calculated as 0.722, 0.352, 0.863, 0.345 and 0.969, respectively, and OR (95% CI) as 0.94(0.65-1.35), 2.25(0.41-12.35), 0.97(0.68-1.38), 2.27(0.41-12.48), and 1.01(0.72-1.40), respectively., Conclusion: Polymorphisms of the rs3819024 and rs8193037 loci of the IL-17A gene are not associated with the susceptibility to IS among ethnic Han Chinese from Guangxi.

Objective: To evaluate the relationship between osteopontin gene genetic polymorphisms and susceptibility of nasopharyngeal carcinoma in Guangxi Zhuang people., Methods: With a hospital based case-control study, osteopontin gene polymorphisms were compared between patients with nasopharyngeal carcinoma and healthy outpatients as a controls in Zhuang population in Guangxi. The single nucleotide polymorphisms at rs1126772 and rs9138 sites of the osteopontin gene were determined by polymerase chain reaction-single base extension technique (PCR-SBE) and DNA sequencing technology. The comparison between genotype and allele frequency distribution differences in case and control group was accomplished by a χ(2) test. The frequencies of haplotypes in osteopontin gene in different groups were analyzed., Results: There were no differences between the patients and controls in the genotype or allele frequencies of osteopontin gene rs1126772 site (, Ga/gg: OR = 0.94, 95%CI 0.37-2.37, χ(2) = 0.182, P = 0.891; AA/GG:OR = 0.86, 95%CI 0.35-2.12, χ(2) = 0.834, P = 0.773) or rs9138 site (, Ca/cc: OR = 1.42, 95%CI 0.88-2.29, χ(2) = 2.023, P = 0.155; AA/CC:OR = 1.77, 95%CI 0.78-4.01, χ(2) = 1.901, P = 0.168). The frequency of GA haplotype in the patients was significantly higher than that in the controls (P = 0.003), and the GA haplotype was associated with a significantly increased risk of nasopharyngeal carcinoma (OR = 4.84, 95%CI 1.59-14.71)., Conclusion: The haplotype GA of osteopontin gene rs1126772 and rs9138 sites increases the risk of nasopharyngeal carcinoma in Guangxi Zhuang people.

Suspended particles (SP) are increasing dramatically in Bohai Bay, China and may affect the growth and composition of phytoplankton assembly. To determine the effects of SP on the growth of two dominant phytoplankton species, Phaeodactylum tricornutum Bohlin and Gymnodinium sp., we cultured and tested their growth characteristics under SP concentrations ranging from 0 g L(-1) to 0.8 g L(-1). Our results show that the increase in the SP concentrations results in significant decrease in the maximum cell densities and the maximum specific growth rates of these two species. The half maximal inhibitory concentration (IC50) of SP to P. tricornutum and Gymnodinium sp. were 1.07 g L(-1) and 0.68 g L(-1) respectively, indicating the inhibitory effect of SP on Gymnodinium sp. was greater than on P. tricornutum. These results suggest that SP inhibits the growth of the two algal species and P. tricornutum is more tolerant to SP than Gymnodinium sp., (Copyright © 2013 Elsevier Ltd. All rights reserved.)