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Purpose: Previous studies showed that long-term use of proton pump inhibitors (PPIs) was associated with cardiovascular events. However, the impact of short-term PPI exposure on intensive care unit (ICU) patients with myocardial infarction (MI) remains largely unknown. This study aims to determine the precise correlation between short-term PPI usage during hospitalization and prognostic outcomes of ICU-admitted MI patients using Medical Information Mart for Intensive Care IV database (MIMIC-IV). Methods: Propensity score matching (PSM) was applied to adjust confounding factors. The primary study outcome was rehospitalization with mortality and length of stay as secondary outcomes. Binary logistic, multivariable Cox, and linear regression analyses were employed to estimate the impact of short-term PPI exposure on ICU-admitted MI patients. Results: A total of 7249 patients were included, involving 3628 PPI users and 3621 non-PPI users. After PSM, 2687 pairs of patients were matched. The results demonstrated a significant association between PPI exposure and increased risk of rehospitalization for MI in both univariate and multivariate [odds ratio (OR) = 1.157, 95% confidence interval (CI) 1.020–1.313] analyses through logistic regression after PSM. Furthermore, this risk was also observed in patients using PPIs > 7 days, despite decreased risk of all-cause mortality among these patients. It was also found that pantoprazole increased the risk of rehospitalization, whereas omeprazole did not. Conclusion: Short-term PPI usage during hospitalization was still associated with higher risk of rehospitalization for MI in ICU-admitted MI patients. Furthermore, omeprazole might be superior to pantoprazole regarding the risk of rehospitalization in ICU-admitted MI patients. [ABSTRACT FROM AUTHOR]

The impact of bank branch expansion on macroeconomic and micro-firm behaviour has been one of the primary focuses in related research fields. However, research has thus far ignored the unintended impact of the increased availability of credit resources on firms' pollution emissions. Therefore, based on firm-level data in China, we explore the impact of the availability of credit resources on firm pollution reduction. The empirical results of this study are as follows. (1) Increased availability of credit resources to firms can significantly reduce pollution emissions. This finding remains robust after a series of robustness tests. (2) The possible path to reduced emissions is through increasing capital investment in production and technological innovation, rather than increasing capital investment in governance. (3) The market access policy for small and medium-sized commercial bank branches further strengthens the effect of credit resource availability on pollution reduction. And the reduction effect is more significant for firms facing strong environmental regulations and weak economic target constraints. These findings provide a new perspective for enterprises to reduce emissions. [ABSTRACT FROM AUTHOR]

Previous studies found that histamine H2 receptor antagonists (H2RAs) had blood pressure lowering and cardioprotective effects, but the impact of H2RAs on the survival outcomes of critically ill patients with essential hypertension is still unclear. The aim of this study was to investigate the association of H2RAs exposure with all‐cause mortality in patients with essential hypertension based on Medical Information Mart for Intensive Care III database. A total of 17,739 patients were included, involving 8482 H2RAs users and 9257 non‐H2RAs users. Propensity score matching (PSM) was performed to improve balance between 2 groups that were exposed to H2RAs or not. Kaplan–Meier survival curves were used to compare the cumulative survival rates and multivariable Cox regression models were performed to evaluate the association between H2RAs exposure and all‐cause mortality. After 1:1 PSM, 4416 pairs of patients were enrolled. The results revealed potentially significant association between H2RAs exposure and decreased 30‐day, 90‐day, and 1‐year mortalities in multivariate analyses (HR = 0.783, 95% CI: 0.696‐0.882 for 30‐day; HR = 0.860, 95% CI: 0.778‐0.950 for 90‐day; and HR = 0.883, 95% CI: 0.811‐0.961 for 1‐year mortality, respectively). Covariate effect analyses showed that the use of H2RAs was more beneficial in essential hypertension patients with age ≥ 60, BMI ≥ 25 kg/m2, coronary arteriosclerosis, stroke, and acute kidney failure, respectively. In conclusion, H2RAs exposure was related to lower mortalities in critically ill patients with essential hypertension, which provided novel potential strategy for the use of H2RAs in essential hypertension patients. [ABSTRACT FROM AUTHOR]

By extracting information from various original materials and using geography departments, curricula, and faculty as indicators, this paper contributes to the discussion of the development of geography in higher education in China from 1904 to 1949. Four mutual connections are outlined. First, the development of geography in higher education is inextricably linked to social and political changes. Second, geography in higher education during the period concerned progressed in fits and starts, which affected its distribution. Third, geography departments were split into two categories according to the type of higher educational institution, which created differences in the tasks, curricula, and faculty of these departments. Fourth, faculty were trained in both domestic and foreign universities, and Western universities made an obvious contribution to the growth of qualified academic faculty. Simultaneously, universities where qualified academic faculty were trained were centralized both in domestic and foreign aspects. The special role of geographers returning from overseas study, the particularity of geography in higher education in China, and the connection between Chinese and foreign geography are also discussed in terms of geography departments, curricula, and faculty.

Long-term stability is crucial in cropland for maintaining stable agricultural production and ensuring national food security. However, relatively few studies have been conducted on the long-term stability of cropland at the national level. This study assessed the long-term stability of cropland in China from 1990 to 2018 using a fine-resolution land use dataset. The experimental results indicated that the average area of unstable cropland in China from 1990 to 2018 amounted to 2.08 ×   10 6 km2, 47.31% of the total. The Qinghai–Tibet Plateau exhibited the highest average proportion of unstable cropland at 65.9%, followed by the northern arid and semiarid region, Southern China, and the Yunnan–Guizhou Plateau. The quantity of unstable cropland in China initially declined before increasing, reaching a final growth rate of 5.09%. Furthermore, this study explored the relevant driving factors of cropland's long-term stability from both natural factors and human activities based on artificial neural networks. The relative importance of distance to vegetation reached a value of 0.30, indicating that it had the most significant influence on the long-term stability of cropland, followed by relief amplitude and soil type. This phenomenon may be attributed to the inadequate execution of the Grain for Green Policy and the requisition–compensation balance of cropland policy, along with the depletion of young and middle-aged laborers due to urban migration from rural areas. Local governments should focus on addressing the unsustainable exploitation of sloped land in rural mountainous or hilly regions while preventing urban developers from appropriating fertile cropland to compensate for less fertile areas. [ABSTRACT FROM AUTHOR]

This study was to investigate the prevalence and severity of children's dental fluorosis (DF) in Shandong and identified the potential risk factors for DF. A total of 87 villages in Shandong were investigated to calculate the prevalence of DF and Community Fluorosis Index (CFI) in 2018–2019. Six hundred and seventy children were enrolled to identify the potential risk factors using univariate and multivariate logistic regressions. Goodman–Kruskal Gamma was used to explore the factors related to the severity of DF. In 87 villages, 1249 of 8700 (14.36%) children still have DF. The prevalence of DF in most villages was below 40% in 2018–2019. Water fluorine concentration when selected for the study and urinary fluorine concentration were related to the risk of DF (P < 0.001). Some eating habits, like lower frequency of eating fresh vegetables, eggs, and beans, were associated with the risk of DF (P < 0.001). The high water fluorine concentration, and lower frequency of eating fresh vegetables, eggs, and beans were also related to the severity of DF (P < 0.001). DF in children in Shandong province is still a common endemic disease. This study tries to provide a useful guide for the prevention and control of DF. [ABSTRACT FROM AUTHOR]

Objectives: As one of the most common hereditary diseases, thalassemia affects a large number of people in China. The aim of this study was to investigate the feasibility of a method based on next-generation sequencing (NGS) for screening of thalassemia carriers among high school students in the Shaoguan area. Materials and Methods: The NGS-based method was performed using 25,910 high school students recruited from 38 schools. The screening yield was systematically analyzed. Before screening, a lecture on how the disease is inherited, the symptoms of thalassemia, and how to prevent it was given to 28,780 students. Results: Implying successful delivery of information on the disease, 90.03% (25,910 of 28,780) of the students agreed to join this program for thalassemia screening. A thalassemia carrier rate of 15.99% (4144 of 25,910) was found. Also, 69 rare genotypes (28 of α-thalassemia and 41 of β-thalassemia) and 9 novel variants were identified. Conclusions: This NGS-based method provided a feasible platform for high school population thalassemia screening. Combined with a clinical follow-up strategy, it could help eventually to prevent the births of affected children. [ABSTRACT FROM AUTHOR]

Tea (Camellia sinensis L.) is one of the most important and traditional economic crops widely cultivated in the subtropical regions of China, which are usually developed from forestland. Soil enzyme activity is an important indicator of soil fertility and nutrient transformation. The purpose of this study is to investigate the seasonal dynamic characteristics of soil properties and enzyme activities of different planting patterns in Wuyishan city, and to provide theoretical basis for reasonable evaluation of soil ecological effects of organic tea cultivation. In this paper, three different planting patterns (forestland, conventional and organic tea gardens) were selected as the research objects. Soil samples were collected in May, August, November and February from 2021 to 2022. The soil properties and enzyme activities (urease, nitrate reductase, polyphenol oxidase, catalase, invertase and acid phosphatase) were determined in different seasons, and the dynamic changes with seasons were also investigated. The results show that: comparing with the forestland, the contents of soil ammonium nitrogen, total phosphorus, available phosphorus and available potassium increased significantly in the conventional tea garden, while the total potassium and pH decreased significantly. Compared with the conventional tea garden, the soil organic matter and total nitrogen contents increased significantly in the organic tea garden. The soil total phosphorus, available phosphorus, total potassium and available potassium contents decreased significantly. The soil pH also increased, and the proportion of soil nutrients was more coordinated. The effects of planting pattern and season and their interactions on urease and peroxidase activities were significant. Compared with the forestland, the soil urease, polyphenol oxidase, catalase and acid phosphatase activities decreased by 12.05% to 63.55% in the conventional tea garden, while urease activities significantly increased by 324.95% in the organic tea garden, and the soil nitrate reductase activities were not changed by planting mode. In general, the soil urease, polyphenol oxidase, invertase and acid phosphatase activities were significantly higher in summer and autumn (May and August) than those in winter and spring (November and February). The highest soil nitrate reductase and catalase activities were found in spring (February). The results of permutational multivariate analysis of variance show that the effect of planting pattern on the overall soil physical and chemical properties was much greater than that of seasonal changes. Redundancy analysis shows that soil environmental factors explained 77.03% of the variation in soil enzyme activity, and the soil organic matter, total nitrogen, ammonium nitrogen, total phosphorus, soil available phosphorus, total potassium, available potassium and pH were the main driving factors of soil enzymes. In summary, the conversion of forestland into tea gardens has a significant impact on soil properties and enzyme activities. Conventional planting leads to the accumulation of available phosphorus and potassium in tea garden soil and the decrease of soil enzyme activity, while organic planting improves soil enzyme activity and enhances soil carbon and nitrogen nutrient supply capacity, and thus is beneficial for maintaining a sustainable ecosystem in tea garden soil. [ABSTRACT FROM AUTHOR]

The economic disparity between southern and northern China has widened in the past decade. This article explores the roles of the north-south stretched backbone high-speed rails (HSRs) in the widened north-south economic gap in China. By constructing panel data of 283 cities between 2005 and 2016 and estimating the difference in GDP and per-capita GDP of northern and southern cities before and after the first north-south stretched HSR, we show that the north-south economic gap widened by about 8% as the opening of the Beijing-Shanghai HSR, the first north-south stretched HSR. Further channel analysis reveals that the north-south gaps in population, fixed asset investment, public expenditure, and the relative size of secondary industry to tertiary industry also widened. These results suggest that fast transportation improvement caused by long-distance backbone HSRs can contribute to accelerating the large-scale regional disparity. [ABSTRACT FROM AUTHOR]

As the main expenditure item in water balance, evapotranspiration has an important impact on the surface ecosystem. Assessing the impact of changes in meteorological elements on evapotranspiration is essential to identify the spatiotemporal heterogeneity of hydrographic responses to climate changes. Based on the actual evapotranspiration (ETa) product (GPR-ET) generated by Gaussian process regression (GPR), as well as temperature and precipitation datasets, our study employed various statistical analysis methods, including geographic detector, the center of gravity migration model, spatial variation coefficients, and partial differential models, to investigate the spatiotemporal variation in ETa in China from 2000 to 2018. The analysis covered future trends in ETa changes and the contribution of meteorological factors. Our results showed that the ETa in northwest China had stronger spatial heterogeneity and the mean value was generally lower than that in the southeast. But the center of gravity of ETa was shifting towards the northwest. In most areas, the future trend was expected to be inconsistent with the current stage. ETa in the regions of north and west was mainly driven by precipitation, while its increase in southeast China was largely attributed to temperature. In addition to spatial variations, the joint enhancement effect of temperature and precipitation on ETa exists. According to the contribution analysis, precipitation contributed more to the change in ETa than temperature. These findings have enhanced our comprehension of the contribution of climate variability to ETa changes, providing scientific proof for the optimization apportion of future water resources. [ABSTRACT FROM AUTHOR]

In this study, three typical and most extreme precipitation events in the history of North China are analyzed and compared in terms of accumulated precipitation and synoptical circulation using surface station observations of China and the ERA5 dataset. The three events happened in August 1963 ("63.8" event, hereafter), August 1975 ("75.8" event), and July 2021 ("21.7" event), respectively, mainly in Hebei and Henan Provinces of North China. The results show that the maximum daily and 4-day accumulated precipitation of all three events exceeded 500 mm and 800 mm, with many stations' daily precipitation ranking Top 1. The "63.8" event persisted for the longest time, affected the largest area, and rained the most in 7 days (over 1000 mm). The "75.8" event was characterized by the most extreme daily precipitation and a concentrated area. All three events characterize a normal northward subtropical high that was located in North China and Northeast China. At 500 hPa, the area from South China to the South China Sea was dominated by a uniform pressure field. In the upper levels, there were troughs and divergence anomalies in all three events. In the low levels, there were anomalous low-level jets and the associated water vapor flux anomalies, which were located at different levels and came from different directions. Stable synoptical circulation and persistent jet and water vapor flux anomalies are the key factors in these extreme events. [ABSTRACT FROM AUTHOR]

Purpose: This study aims to evaluate the effectiveness of different prefabricated construction (PC) policies using a case study in Wuhan, considering the local context. Design/methodology/approach: The effectiveness of PC policies is falling behind expectations. The main reason lies in an insufficient understanding of the policy impacts. An agent-based model was built by choosing the residential sector in a typical large city of Wuhan, China, as the study case. Different cost reduction scenarios were introduced for investigating the PC policy effectiveness. The proposed model and simulation approach can be used for other cities and generalized to the whole Chinese PC industry with the potential to include more local policies and corresponding data. Findings: Simulation results show that carbon emission reduction will be between 60,000 and 80,000 tons with policy incentives, nearly double that of the no policy intervention scenario. The target of 30% PC in all new buildings by 2026 in China is achievable with the subsidy policies of linear cost reduction, or cost reduction conforms to the learning curve. Practical implications: Simulation results of three kinds of policy show that subsidy policy optimization is necessary regarding reducing the level of subsidy needed. The carbon credit policy is not essential since it has little influence on PC development. Implementing the project procurement restriction policy is not recommended if the scale of development of PC is more important than achieving the development target. Originality/value: This study can help the government and developers make better policy and strategic decisions on PC development and boost the sustainability transition of the construction industry. [ABSTRACT FROM AUTHOR]

Background: There are few studies that focus on the impact of online physical education teaching on college students during the coronavirus disease 2019 (COVID-19) pandemic. This research focuses on the impact of online physical education among medical school students in China by comparing physical fitness test results for three consecutive years from 2019 to 2021. Method: This study is a longitudinal survey. The subjects of the experiments were students enrolled in a medical school who completed a physical fitness test for three consecutive years from 2019 to 2021. The student subjects were divided into two groups, namely, male and female. The test indices included body mass index (BMI), vital capacity (VC), 50-metre run, sit-and-reach, standing long jump, pull-up (male), 1000-metre run (male), sit-ups (female) and 800-metre run (female). Repeated measures ANOVA method was used in physical fitness test indices at three consecutive time points ranging from 2019 to 2021. The Greenhouse-Geisser correction was applied when Mauchly's hypothesis test did not meet the assumption of sphericity, and the Bonferroni method was used for pairwise comparisons. Results: A total of 3360 students (1490 males and 1870 females) completed physical fitness tests in three consecutive years from 2019 to 2021. The proportion of overweight and obesity in male students was significantly higher than that in female students (28.0% vs. 12.7%). For all subjects, in 2020, the BMI and VC indexes improved, while the 800-/1000-metre running indexes declined. In 2021, all indexes except sit-and-reach increased. Conclusion: The pairwise comparisons of physical fitness test results from 2019 to 2021 show that online physical education is effective in improving all items except long-distance running. Future research needs to involve a larger and geographically more dispersed sample to further analyse the effectiveness of online physical education. [ABSTRACT FROM AUTHOR]

Two new species of genus Perspiria were discovered from the subtidal sediments of Bohai Bay of China and described as Perspiria macramphida sp. nov. and Perspiria major sp. nov. Perspiria macramphida sp. nov. is characterised by the large and longitudinal loop-shaped amphidial fovea, partially surrounded with cuticular striations; conical buccal cavity with a dorsal tooth; spicules arcuated with enlarged proximal end and ventral velum, 53–61 µm long; 15–16 papillary precloacal supplements; and tail conico-cylindrical with prominent transverse striations except its terminal end. Perspiria major sp. nov. is characterised by its small unispiral amphidial fovea looking like a double circle in outline, partially surrounded with cuticular striations; conical buccal cavity with a small dorsal tooth; pharynx with a pear-shaped terminal bulb; tail short, conico-cylindrical; spicules strongly curved with heart-shaped proximal end, without ventral velum; and lacking precloacal supplements. An updated key for valid species of Perspiria is provided. [ABSTRACT FROM AUTHOR]

Drug‐related adverse reactions are among the main reasons for harm to patients under care worldwide and even their deaths. The pharmacovigilance system has been proven to be an effective method of avoiding or alleviating such adverse events. In 2019, after two decades of implementation of the drug‐related adverse reaction reporting system, China formally implemented a pharmacovigilance system with the Pharmacovigilance Quality Management Standards and a series of supporting technical documents created to improve the safety of medication given to patients. China's pharmacovigilance system has faced many problems and challenges during its implementation. This spontaneous reporting system is the main source of data for China's medication vigilance activities, but it has not provided sufficiently powerful evidence for regulatory decision‐making. In conformity with the health‐centred drug regulatory concept, the Chinese government has accelerated the speed of examination and approval of urgently needed clinical drugs and orphan drugs along with the requirement to improve the safety supervision of these drugs after their listing. China's marketing authorization holders (MAHs) must strengthen their pharmacovigilance capabilities as the primary responsible departments for drug safety. Chinese medical schools generally lack professional courses on pharmacovigilance. The regulatory authorities have recognized such problems and have made efforts to improve the professional capacity of pharmacovigilance personnel and to strengthen cooperation with stakeholders through the implementation of an action plan of medication surveillance and the establishment of a patient‐based adverse events reporting system and active surveillance systems, which will help China bridge the gap to bring its pharmacovigilance practice up to standards. [ABSTRACT FROM AUTHOR]

As a Chinese solution to build a community of human destiny, Belt and Road Initiative (BRI) has shown China's international responsibility by promoting its green development. Based on the annual panel data of Chinese cities from 2004 to 2018, this paper systematically explores the effect of BRI on the Green Total Factor Productivity (GTFP) of cities along its domestic route using the difference-in-differences (DID) method. The results of the study show that (1) BRI significantly increases the GTFP of cities along its domestic route, and this finding holds after excluding a series of robustness tests such as endogeneity issues and other policy disturbances. (2) BRI promotes the growth of GTFP in the region mainly through improving science and technology innovation, increasing foreign direct investment and enhancing trade cooperation. (3) From the perspective of heterogeneity, the promotion effect of BRI on the GTFP of inland cities along the route is much higher than that of coastal cities, and cities along the route with stronger environmental concerns have a more significant enhancement effect. (4) Based on the policy context and the undertaking of role functions, there is a significant positive linkage effect between BRI Initiative and the Free Trade Zone (FTZ) construction in promoting GTFP growth. (5) From a spatial perspective, BRI has not only increased the GTFP of cities along the route, but also radiated the growth of GTFP in neighboring cities along the route. The conclusion of this paper provides a policy reference and theoretical basis for further building the green "Belt and Road" and promoting the sustainable development of China's economy and high-quality transformation. [ABSTRACT FROM AUTHOR]

It is crucial to establish a robust chronology for understanding late Quaternary sedimentation processes and environment changes in response to sea-level fluctuation on shelves. The shelf of the East China Sea (ECS) is featured by huge terrigenous sediment input and striking land -sea interaction during the late Quaternary. However, there remains controversy in chronostratigraphic rebuilding of transgression and regression deposits during eustatic-glacial cycles, mainly due to a lack of reliable dating data. In this study, an extensive comparison of 17 optically stimulated luminescence (OSL) and 15 AMS 14C ages from core TBF-1 (upper 40 m) provides a constraint in chronostratigraphic reconstruction since Marine Isotope Stage (MIS) 5. OSL ages range from 9.5 ± 0.7 to 67.3 ± 4.8 ka at depths from 2.00 to 28.00 m, while 14C ages range from 6645 to 41435 cal a BP at depths from 0.02 to 17.52 m. Regression analysis demonstrates a high level of agreement between OSL and 14C ages, with r2 values of 0.91 and 0.90, respectively. For Holocene sediments (U1), both OSL and 14C methods are applicable in tidal sand ridges, however, it should be noted that 14C ages may exhibit a young bias of up to 3 ka. For pre-Holocene sediments (U6-U2), OSL ages are robust within saturation limitation of OSL signal (D e up to ca. 166 Gy), cross-checked by feldspar post-IR IRSL (pIRIR) dating protocol. Nevertheless, the shell 14C ages (11620 and 10390 cal a BP at depths of 13.95–14.56 m) in Last Glacial Maximum (LGM) fluvial sediments of U2 are significantly underestimated, because of their susceptibility to recrystallization and overgrowth, resulting in carbon exchange with environment. While the peaty layer's14C age in deltaic deposition (17.50 m, U5) was determined to be 36420 cal a BP, coincided with OSL age of 39.6 ± 3.9 ka. The chronostratigraphy since MIS 5 for core TBF-1 exhibits a significant correlation with previously published cores SFK-1, DZQ4, and DH02, on the ECS outer shelf. Through the evaluation of those underestimated 14C ages and saturated OSL ages, we re-elucidated the primary sedimentary facies and their respective formation periods. This sedimentary stratigraphic illustration exhibits significant consistency with eustatic-glacial cycles. The renewed chronological framework for ECS shelf allows better correlation between the late Quaternary sedimentary evolution and the land-sea interaction on open shelves dominated by siliciclastic sedimentation. [ABSTRACT FROM AUTHOR]

The distributions of pH, total alkalinity (Alk), dissolved inorganic carbon (DIC) and the partial pressure of carbon dioxide (pCO2) were investigated in Bohai Bay in northeastern China during summer 2020. The CO2 air–sea fluxes were also estimated for that summer. The results of the survey showed that the distributions of Alk and DIC in surface and bottom seawater were generally consistent, with the maximum values of DIC and Alk appearing at the same station, station BHB33 at the surface and station BHB35 at the bottom, which were in the middle of the bay. The minimum values of pH and the maximums value of pCO2 were both located at station HH2 at the surface and station HH3 at the bottom, which were near the mouth of the Haihe River. Bohai Bay was estimated as a source of CO2 in summer 2020. Carbonate species presented significant correlations with biochemical parameters, such as chlorophyll α (Chl- α), dissolved oxygen (DO) and nutrients. In addition, terrestrial inputs and human activities, together with the poor hydrodynamics of Bohai Bay are also the main factors influencing the carbonate species in Bohai Bay. [ABSTRACT FROM AUTHOR]

Three-year field experiments were conducted to investigate the effects of ridge film mulching plus furrow planting (RFMF) and traditional flat planting (FP) on the seed quality, oil yield and nitrogen-use efficiency of winter oilseed rape (Brassica napus) and to determine the optimal rate of nitrogen (N) application under the two planting patterns. Six N rates, 0, 60, 120, 180, 240 and 300 kg N ha−1, were applied under both patterns. RFMF significantly increased seed yield, oil yield, N agronomic efficiency (NAE) and N partial factor productivity (NPFP) by 15.5–43.5%, 18.0–48.3%, 2.1–70.6% and 17.9–48.2% respectively, compared with FP. The optimal N application rates were 235 and 218 kg N ha−1 under RFMF and FP, respectively. In conclusion, RFMF could be adopted with N rate of 235 kg N ha−1 for the cultivation of winter oilseed rape in northwest China to improve shoot nutrient uptake, oil yield and N use efficiencies. [ABSTRACT FROM AUTHOR]

Simple Summary: Sarcocystis spp. are cyst-forming intracellular protozoan parasites characterized by a two-host prey–predator life cycle. The alpaca (Vicugna pacos) is one of the South American camelids (SACs), and in recent years, this animal was introduced to China to be raised for its meat, skin, and wool and to be kept as tourist attractions and as pets. There is considerable confusion regarding the classification and nomenclature of the species of Sarcocystis in SACs. Two Sarcocystis species, named S. auchenia and S. masoni, are currently regarded as valid in SACs based on sarcocyst morphology and 18S rDNA sequences. However, the definitive host of S. masoni remains unknown. Here, S. masoni sarcocysts in an alpaca were morphologically described and molecularly characterized. Furthermore, the life cycle of S. masoni was completed via experimental animal infection. The present analysis showed that S. masoni has a close relationship with S. cameli in the dromedary camel (Camelus dromedaries), and the relationship between the two parasites needs to be clarified in the future. Only 18S rDNA sequences of Sarcocystis spp. in South American camelids (SACs) are deposited in GenBank as references, and the definitive host of S. masoni in SACs is still unclear. Here, S. masoni sarcocysts detected in an alpaca (Vicugna pacos) in China were investigated with the aid of light (LM) and transmission electron (TEM) microscopy, and characterized using four genetic markers, i.e., 18S rDNA, 28S rDNA and ITS, and the mitochondrial cox1. Additionally, the life cycle of the parasite was completed via experimental animal infection. Under LM, S. masoni sarcocysts exhibited numerous 1.3–2.1 μm conical protrusions. Under TEM, the sarcocyst wall contained conical, cylindrical, or irregular-shaped villar protrusions, similar to type 9j. Two dogs (Canis familiaris) fed S. masoni sarcocysts shed sporocysts with a prepatent period of 8–9 days. The newly obtained 18S rDNA sequences showed 98.4–100% identity with those of S. masoni in SACs previously deposited in GenBank. Interestingly, the newly obtained sequences of 18S rDNA and mitochondrial cox1 shared 99.6–100% and 98.2–98.5% identity, respectively, with those of S. cameli in dromedary camels (Camelus dromedaries). Phylogenetic analysis based on sequences of 18S rDNA, 28S rDNA, or mitochondrial cox1 revealed that S. masoni has a close relationship with Sarcocystis spp. in ruminants. The relationship between S. masoni and S. cameli deserves to be further clarified in the future. [ABSTRACT FROM AUTHOR]

Actinidia arguta Sieb.Zucc. is a fruit that is rich in flavonoids. Nevertheless, details of flavonoid formation and the potential mechanism behind flavonoid biosynthesis have not previously been reported. In order to explore the biosynthetic regulation mechanism of flavonoids in A. arguta Sieb.Zucc., we conducted a combination of extensive targeted metabolite analysis and analyzed transcriptomes to determine the flavonoids present and the genes bound up with flavonoid biosynthesis in the two main cultivated varieties of A. arguta Sieb.Zucc. in Northern China. The maturity period is from August to September. A total of 118 flavonoids were found in fruits. Among them, 39 flavonoids were accumulated at significant levels after fruit ripening. Transcriptome analysis indicated that most flavonoid biosynthesis structural genes and certain regulatory genes exhibited differential expression between the two varieties. Correlation analysis of transcriptome and metabolite profiles showed that the ways of expression of 21 differentially expressed genes related to structure and regulation between the 2 varieties were more highly correlated with 7 flavonoids after fruit ripening. These results contribute to the development of A. arguta Sieb.Zucc. as a food and drug homologous functional food. [ABSTRACT FROM AUTHOR]

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Zooplankton play a pivotal role in connecting primary producers and high trophic levels, and changes in their temporal and spatial distribution may affect the entire marine ecosystem. The spatial and seasonal taxonomic composition patterns of mesozooplankton in Bohai Bay were investigated in relation to a number of water parameters. Bohai Bay is a eutrophic semi-enclosed bay with dynamic physico-chemical conditions influenced by terrestrial inputs and seawater intrusion. The results showed that under the condition of terrigenous input, the diversity of mesozooplankton species near the eutrophic Haihe River Estuary and Jiyun River Estuary was lower than that in the central Bohai Bay, with gelatinous Oikopleura dioica as the dominant species. The mesozooplankton diversity was highest in the bay mouth affected by seawater intrusion, and the dominant oceanic species, mainly copepods Corycaeus affinis, Calanus sinicus, and Oithona similis, entered the inner bay from the bay mouth. Meanwhile, the abundance of mesozooplankton in summer was significantly higher than that in autumn. Compared with historical data, the dominant species in Bohai Bay has evolved from arrow worm Sagitta crassa to copepod Paracalanus parvus, probably due to global warming, indicating the effects of human activities on the succession of mesozooplankton community. [ABSTRACT FROM AUTHOR]

Hangzhou Bay is facing severe anthropogenic perturbation because of its geographic position. We studied species-specific bioaccumulation of metals in commercially important fishes and shellfishes, and calculated the potential human health hazards through their consumption, which has not been reported earlier from this area. The hierarchy of metal concentration in organisms was in the decreasing order of Zn (10.32 ± 7.13) > Cu (2.40 ± 2.66) > As (0.42 ± 0.26) > Cr (0.11 ± 0.08) > Cd (0.07 ± 0.07) > Pb (0.05 ± 0.02) > Hg (0.012 ± 0.009). Except for Cd and As concentrations in fishes, metal concentrations have not exceeded the national and international guideline values. P. laevis and P. trituberculatus were the most bioaccumulative of the species studied. According to the non-carcinogenic risk assessment, children were more susceptible to metal contamination than adults. The carcinogenic risk (CR) values indicated that children were likely to experience carcinogenic threats for taking cancer-causing agents As and Cd through fish consumption. In terms of organisms, intake of two crab species, P. trituberculatus and E. sinensis, as well as the oyster species P. laevis, could be detrimental to consumers. [ABSTRACT FROM AUTHOR]

BACKGROUND: Poor inferior kernel grain filling is a challenge that limits summer maize yield. The effect and mechanism of conservation tillage on improving grain filling of inferior kernel in semi‐arid rained areas remain uncertain and there has been little research on tillage management integrated with straw mulching to improve soil water content and photosynthesis in the Loess Plateau region. A 2 year (2019–2020) field experiment was established to study the impact of tillage practices on soil water content and summer maize root system morphology, photosynthetic capacity, inferior kernel grain filling, and grain yield. Treatments included reduced tillage (RT), no tillage (NT), and conventional tillage (CT). RESULTS: Under RT and NT, the final 100‐kernel weight and maximum and mean grain filling rates were higher than CT. Reduced tillage and NT increased soil water content at the jointing stage, silking stage and grain filling stage in comparison with CT. They increased root system morphology and dry matter accumulation, net photosynthetic rate, transpiration efficiency, and stomatal conductance in comparison with CT, and they also decreased intercellular CO2 concentration, and they increased chlorophyll content and above‐ground dry matter accumulation in comparison with CT. Reduced tillage and NT increased evapotranspiration of maize, and ultimately, increased grain yield by 17% and 14%, respectively, in comparison with CT. CONCLUSION: Conservation tillage could promote summer maize photosynthetic capacity and grain filling of inferior kernels by regulating soil water content and root system morphology. © 2021 Society of Chemical Industry. [ABSTRACT FROM AUTHOR]

Purpose: Modern construction projects are increasingly complex and rely heavily on multi-discipline collaboration, and this leads to a more and more decentralized project-based structure widely adopted in the construction industry. While job satisfaction (JS) and job performance (JP) have been heavily studied previously, few considered the impact of organizational structure and none investigated the relationship between the organizational decentralization degree with JS and JP. This research aims to fill this research gap and investigate the impacts of organizational decentralization degree on JS and JP and facilitate a better project management practice for large-scale construction projects. Design/methodology/approach: This research firstly establishes four hypotheses based on the literature review on general project-based organizations, then the hypotheses are tested by a survey covering 25 large complex construction projects in China. A hierarchical linear model analysis was carried out to analyze the survey data and to study the relationships between organizational decentralization degree, job satisfaction and job performance. Findings: Analysis results show that projects' employees' JS and JP are positively correlated with the construction project organizations' decentralization degree, respectively. The decentralization degree has a higher impact on JS than on JP. Employees' JP is positively correlated with their JS, and a higher decentralization degree leads to a more significant positive impact that JS puts on JP. Originality/value: The findings are new evidence of how construction organization structure and its decentralization degree can affect project employees' JS and JP. This research provides valuable guidance for the industry's management practice and is particularly important for large, complex and highly decentralized construction projects. [ABSTRACT FROM AUTHOR]

Background: Data on the genus Sarcocystis in insectivores are limited. The Asian gray shrew Crocidura attenuata is one of the most common species of the insectivore family Soricidae in South Asia and Southeast Asia. To our knowledge, species of Sarcocystis have never been recorded previously in this host. Methods: Tissues were obtained from 42 Asian gray shrews caught in 2017 and 2018 in China. Sarcocysts were observed using light microscopy (LM) and transmission electron microscopy (TEM). To describe the parasite life cycle, muscle tissues of the host infected with sarcocysts were force-fed to two beauty rat snakes Elaphe taeniura. Individual sarcocysts from different Asian gray shrews, and oocysts/sporocysts isolated from the small intestines and feces of the experimental snakes, were selected for DNA extraction, and seven genetic markers, namely, two nuclear loci [18S ribosomal DNA (18S rDNA) and internal transcribed spacer region 1 (ITS1)], three mitochondrial genes [cytochrome oxidase subunit 1 (cox1), cox3 and cytochrome b], and two apicoplast genes (RNA polymerase beta subunit and caseinolytic protease C), were amplified, sequenced and analyzed. Results: Sarcocysts were found in 17 of the 42 (40.5%) Asian gray shrews. Under LM, the microscopic sarcocysts showed saw- or tooth-like protrusions measuring 3.3–4.5 μm. Ultrastructurally, the sarcocyst wall contained numerous lancet- or leaf-like villous protrusions, similar to those described for type 9h of the common cyst wall classification. The experimental beauty rat snakes shed oocysts/sporocysts measuring 11.9–16.7 × 9.2–10.6 μm with a prepatent period of 10–11 days. Comparison of the newly obtained sequences with those previously deposited in GenBank revealed that those of 18S rDNA and cox1 were most similar to those of Sarcocystis scandentiborneensis recorded in the tree shrews Tupaia minor and Tupaiatana (i.e., 97.6–98.3% and 100% identity, respectively). Phylogenetic analysis based on 18S rDNA or ITS1 sequences placed this parasite close to Sarcocystis spp. that utilize small animals as intermediate hosts and snakes as the known or presumed definitive host. On the basis of morphological and molecular characteristics and host specificity, the parasite was proposed as a new species, named Sarcocystis attenuati. Conclusions: Sarcocysts were recorded in Asian gray shrews, to our knowledge for the first time. Based on morphological and molecular characterization, a new species of parasite is proposed: Sarcocystisattenuati. According to the LM and TEM results, S. attenuati sarcocysts are distinct from those of Sarcocystis spp. in other insectivores and those of S. scandentiborneensis in tree shrews. The 18S rDNA or cox1 sequences of Sarcocystis attenuati shared high similarity with those of Sarcocystisscandentiborneensis, Sarcocystis zuoi, Sarcocystis cf. zuoi in the Malayan field rat, and Sarcocystis sp. in the greater white-toothed shrew. Therefore, we suggest that more research on the relationships of these closely related taxa should be undertaken in the future. [ABSTRACT FROM AUTHOR]

Climate change could negatively alter plant ecosystems if rising temperatures exceed optimal conditions for obtaining carbon. The acclimation of plants to higher temperatures could mitigate this effect, but the potential of subtropical forests to acclimate still requires elucidation. We used space-for-time substitution to determine the photosynthetic and respiratory-temperature response curves, optimal temperature of photosynthesis (T opt), photosynthetic rate at T opt, temperature sensitivity (Q 10), and the rate of respiration at a standard temperature of 25°C (R 25) for Pinus taiwanensis at five elevations (1200, 1400, 1600, 1800, and 2000 m) in two seasons (summer and winter) in the Wuyi Mountains in China. The response of photosynthesis in P. taiwanensis leaves to temperature at the five elevations followed parabolic curves, and the response of respiration to temperature increased with temperature. T opt was higher in summer than winter at each elevation and decreased significantly with increasing elevation. Q 10 decreased significantly with increasing elevation in summer but not winter. These results showed a strong thermal acclimation of foliar photosynthesis and respiration to current temperatures across elevations and seasons, and that R 25 increased significantly with elevation and were higher in winter than summer at each elevation indicating that the global warming can decrease R 25. These results strongly suggest that this thermal acclimation will likely occur in the coming decades under climate change, so the increase in respiration rates of P. taiwanensis in response to climatic warming may be smaller than predicted and thus may not increase atmospheric CO2 concentrations. [ABSTRACT FROM AUTHOR]

Background: Pharmacovigilance is a science that plays a significant role in reducing ADRs and helps predict adverse reactions to drugs in community. To safely use drugs in treatment and prevention of disease, adverse drug reaction has been paid more attention.Objectives: To evaluate the future needs of existing systems, the paper investigated the current state of pharmacovigilance and the reporting of ADR in Chinese hospitals.Methods: This cross-sectional, questionnaire-based study involved 10,063 pharmacists, doctors, and nurses from primary, secondary, and tertiary hospitals in all 31 provinces of China. It was commissioned by the National Centre for ADR Monitoring of China and conducted in March 2020. Three areas were assessed: sociodemographic characteristics of participants, awareness of the pharmacovigilance system, and the current state of hospitals' reporting of ADRs. Chi-square tests were used to calculate P values.Results: Health care professionals had heard the term "pharmacovigilance" previously (89.40%) and knew the reporting object (68.47%), content (65.94%), and range (64.83%) of pharmacovigilance. Most hospitals dispatched responsible professionals (87.64%) and departments (86.25%) to monitor ADR reporting. A total of 58.66% of tertiary medical, 45.25% of secondary, and 38.90% of primary hospitals extracted ADRs from a hospital information system. Moreover, 53.09% of tertiary medical, 38.93% of secondary, and 23.89% of primary hospitals had established a prescription automatic screening system to warn about risks for ADRs. Health care professionals' reports (99.92%) and patient feedback (77.99%) were included in most hospitals' ADR reporting.Conclusions: Chinese health care professionals generally have good awareness of pharmacovigilance, and pharmacovigilance is relatively more advanced in China compared to other developing countries. [ABSTRACT FROM AUTHOR]

Sediment is thought to be a vital reservoir for antibiotic resistance genes (ARGs). Often, studies describing and comparing ARGs and their potential hosts in sediment are based on single DNA extractions. To date, however, no study has been conducted to assess the influence of DNA extraction efficiency on ARGs in sediment. To determine whether the abundance of ARGs is underestimated, we performed five successive extraction cycles with a widely used commercial kit in 10 sediment samples collected from the Haihe River and Bohai Bay. Our results showed that accumulated DNA yields after five extractions were 1.8–3.1 times higher than that by single DNA extractions. High-throughput sequencing showed that insufficient DNA extraction could generate PCR bias and skew community structure characterization in sediment. The relative abundances of some pathogenic bacteria, such as Enterobacteriales, Lactobacillales, and Streptomycetales, were significantly different between single and successive DNA extraction samples. In addition, real-time fluorescent quantitative PCR (qPCR) showed that ARGs, intI 1, and 16S rRNA gene abundance strongly increased with increasing extraction cycles. Among the measured ARGs, sulfonamide resistance genes and multidrug resistance genes were dominant subtypes in the study region. Nevertheless, different subtypes of ARGs did not respond equally to the additional extraction cycles; some continued to have linear growth trends, and some tended to level off. Additionally, more correlations between ARGs and bacterial communities were observed in the successive DNA extraction samples than in the single DNA extraction samples. It is suggested that 3–4 additional extraction cycles are required in future studies when extracting DNA from sediment samples. Taken together, our results highlight that performing successive DNA extractions on sediment samples optimizes the extractable DNA yield and can lead to a better picture of the abundance of ARGs and their potential hosts in sediments. [ABSTRACT FROM AUTHOR]

Sustainable supply chain emerges as a major business trend essential to long-term competitive advantage. Relevant corporate decisions concern a broad range of factors and require novel analytical models for critical control. This study conducts mathematical analyses to identify the factors that are vital yet receiving insufficient attention from researchers and practitioners. Valid survey observations were collected from 113 enterprises in China, the biggest emerging economy that faces the dilemma between development and sustainability. Grey relational analysis (GRA) and interpretative structural modeling (ISM) assess the importance levels of contextual and organizational factors and explore their joint effects. Validated with conventional expert interviews, the results prioritize the factors that play crucial roles in sustainable supply chains. In particular, enterprises should pay close attention to three factors: corporate collaboration, clean production and supplier selection, which provide useful clues on the best practices of formulating low-carbon decisions. With a better understanding of critical factors, enterprises may make supply chains more sustainable with limited resources. To enhance the generalizability of findings, future studies may collect more observations from multiple countries and validate the results in the settings of global supply chains. [ABSTRACT FROM AUTHOR]

A general relationship between the nitrogen (N) and phosphorus (P) content of all plant organs (e.g. leaf, stem, and root) is hypothesized to exist according to whole-plant economics spectrum (PES) theory, but the evidence supporting these expected patterns remains scarce. We measured the N and P content of the leaves, twigs and fine roots of 64 species in three different forest communities along an elevational gradient (evergreen broad-leaved forest, 1319 m a.s.l. coniferous and broad-leaved mixed forest, 1697 m a.s.l. and deciduous forest, 1818 m a.s.l.) in the Wuyishan National Nature Reserve, southeastern China. The scaling relationship between the N and P content and the linear regression relationship between the N:P ratio and N and P content were analysed. The leaf N and P content was significantly higher at the high-elevation site than at the low- or middle-elevation sites (P < 0.001). The N and P content followed a power-law relationship with similar scaling slopes between organs. The N (common slope, 1.13) and P (common slope, 1.03) content isometrically covaried among leaves, twigs and roots. The scaling exponents of the N–P relationship were not significantly different from 1.0 in all organs, with a common slope of 1.08. The scaling constants of N–P decreased significantly (P < 0.05) from the highest value in fine roots (β = 1.25), followed by leaves (β = 1.17), to the lowest value in twigs (β = 0.88). Standardized major axis (SMA) analyses and comparisons of 95 % confidence intervals also showed that the numerical values of the scaling slopes and the scaling constants did not differ regardless of elevation. The N content, but not the P content, accounted for a large proportion of the variation in the N:P ratio in leaves (N:P and N: r 2 = 0.31, F = 33.36, P < 0.001) and fine roots (N:P and N: r 2 = 0.15, F = 10.65, P < 0.05). In contrast, the N:P ratio was significantly related to both the N and P content in the twigs (N:P and N: r 2 = 0.20, F = 17.86, P < 0.001; N:P and P: r 2 = 0.34, F = 35.03, P < 0.001, respectively). Our results indicate that different organs of subtropical woody plants share a similar isometric scaling relationship between their N and P content, providing partial support for the PES hypothesis. Moreover, the effects of the N and P content on the N:P ratio differ between metabolic organs (leaves and fine roots) and structural organs (twigs), elucidating the stoichiometric regulatory mechanism of different organs. [ABSTRACT FROM AUTHOR]

Water quality, size, connectivity and other physical properties of hydrological systems might have different functions in the formation and maintenance of biodiversity, but this remains mostly unclear due to the lack of undisturbed sites for experimental modelling. Alpine freshwater habitats such as micro-waterbodies (MWB) represent a kind of natural system suitable for biodiversity research. In order to assess potential linkages between environmental factors, connectivity of MWBs and aquatic species richness, we conducted a pilot study in two separated MWB systems located in Gaoligong Mountain, northwest Yunnan province, China. A total of 27 MWBs have been analyzed, including 22 connected and 5 isolated bodies. 13 conventional environmental factors were tested while all kinds of aquatic macro-organisms were collected and classified. Results showed a high environmental heterogeneity among MWBs and significant differences between the two systems but only a few environmental variables such as the depth of soil bottom, total Nitrogen and altitude were related to species richness and the formation of the community structure. As a benefit from the high environmental heterogeneity, the cascaded MWB systems provided divergent habitats able to support species richness at a higher level than the same number of randomly selected MWBs. This finding supports the idea that habitat connectivity matters also in extremely small aquatic ecosystems. Moreover, although still a preliminary result, a polarization effect within connected chains where edge MWBs host higher taxa and endemic taxa richness as well as larger populations, was detectable. This study gives interesting insights on the spatial processes driving community structure and a new prospective for biodiversity conservation. Since alpine MWBs have significant effects on the maintenance of watershed biodiversity, further research on such small and crucial ecosystems is encouraged. [ABSTRACT FROM AUTHOR]

Through a study of the publication data about translations in the field of geography in China from 1900 to 2017, this paper discusses translation as an inherent factor implying foreign geography's impact on modernising and promoting geography in China. The progress of geographical translation in China has been circuitous and arduous, and can be classified into four distinct yet interconnected phases according to the four‐fold aspects of growth, dominant origin, main field of the translations, and proportion of translations among the selected published works. Although translation has been so ubiquitous in Chinese geography that it seems the impact of foreign geography is inescapable, "impact" cannot be equal to translation. With that in mind, indicators including the number and proportion of translations, the import and absorption of translations, the intertwined variation of translations from various countries in different fields and phases, and the social and political contexts in China are considered. The discussion demonstrates that the role of translation in the growth of geography in China changed situationally, and translation implied not only a "foreign impact" but also a "domestic remodelling" of the discipline. Although the status of geography in China is very different from what it used to be, this conclusion suggests that "importing" quality work is necessary for the further promotion of Chinese geography. [ABSTRACT FROM AUTHOR]

At the corporate level, green innovation is essential for environment protection and sustainable development. Green supply chain management (GSCM) and green information system (GIS) are two important pillars of green innovation. This study investigates the possible alignment between them in terms of the synergistic effect on corporate sustainability. Based on the task-technology fit model, GSCM and GIS can be viewed as the task- and technology-side endeavors. The extant conceptualization of the fit between a task and a technology assumes their interdependence, but efficiency-oriented GSCM and technology-driven GIS are relatively independent from each other as they can be carried out separately. Formed on the basis of spontaneous employee participation in both, their alignment is rather informal than formal. Unlike the regular task-technology fit from a top-down arrangement, such a bottom-up alignment is not the necessary condition for GSCM and GIS to take effects, but adds to their direct impacts on green innovation outcome in a one-plus-one-greater-than-two manner. Survey observations gathered from over 300 organizations in China confirm that the informal alignment between GSCM and GIS enhances economic, operational, environmental and social performances on top of their primary contributions. The findings regarding the synergy between GSCM and GIS on corporate sustainability provide researchers and practitioners helpful insights on how to optimize green innovation effectiveness. [ABSTRACT FROM AUTHOR]

High‐speed rail (HSR) has led to a transportation revolution in China. This paper uses the county‐level panel data of China's Yangtze River Delta to investigate the effect of HSR connection on local economy. To address the issue of endogenous HSR route placement, we use a straight‐line strategy to construct potential HSR connection variables as instrumental variables of the actual HSR connection. Both the difference‐in‐differences and instrumental variable methods show that HSR connection impedes local economy, especially in peripheral regions. The impediment effect is channeled through population reallocation from peripheral to core areas and the restructuring of industries. [ABSTRACT FROM AUTHOR]

Investigates the conditions of teachers under the age of 35 in 14 universities and colleges in Beijing, China. The study measured the young teachers' attitudes pertaining to educational responsibility, political ideology, living conditions, and needs. Suggests that teacher unions help resolve problems through democratic and supervision management. (GG)

Residential satisfaction is closely related to the quality of life of residents, especially for the low-income households. The housing policy in China views public rental housing (PRH) and shanty town renovation as the major livelihood projects. To date very few studies have attempted to examine the residential satisfaction of PRH tenants who used to live in shanty towns. Unlike the popular ordered logistic model in existing Chinese studies that often neglect the parallel regression assumption, this study employ generalized ordered logistic model to investigate the resettled tenants' satisfaction with PRH neighborhood by drawing from a randomly sampled survey of tenants in Wuhan. The empirical analysis suggests that housing and neighborhood characteristics, including per capita living space, housing design, as well as neighborhood and public facilities, exert positive and significant impacts on tenants' residential satisfaction. Lease management and property services are also significant determinants of tenants' satisfaction, whereas rent demonstrates negative and significant impact. The variables of residential attitude such as neighborhood interaction, residence comparison and willingness to live, help to enhance tenants' residential satisfaction. In particular, neighborhood and public facilities are important to predict elderly tenants' satisfaction. The interaction effects show that the socio-demographic variables such as gender, age, education, occupation, income and household size, are significantly negatively correlated with the residential satisfaction. Housing authorities should put in additional effort to enhance the performance of PRH and shanty town renovation programs and improve resettled tenants' quality of life. [ABSTRACT FROM AUTHOR]

As of August 2017, China had encountered five seasonal epidemics of H7N9 avian influenza. To prevent people from contracting H7N9 avian influenza, most cities closed live poultry markets (LPMs) to cut off the source of H7N9 virus. The objective of this study is to assess the impact of LPMs closure on reducing zoonotic transmission of avian influenza A (H7N9) virus and to make specific recommendations on the duration of closing the LPMs. Results show that the closure of LPMs can effectively control the spread of H7N9 avian influenza and reduce the incidence of human infection with H7N9. If cases of H7N9 avian influenza continue to occur, LPMs should close for at least 3-4 weeks in susceptible areas to control the spread of infection. [ABSTRACT FROM AUTHOR]

Background. Acute lung injury (ALI) is a rare but life-threatening pulmonary complication of transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma (HCC). The aim of this study was to characterize the common risk factors, clinical features, imaging findings, treatments, and outcomes of acute lung injury caused by TACE. Methods. A retrospective study was performed on all TACE-associated ALI cases that were diagnosed at authors' hospital from January 2015 to June 2018. Results. The study included 14 ALI cases where the mean age of patients was 60.9±11.7 years (range 41-82 years), with a mean onset time of 2.4±1.6 d after TACE. Of the 14 patients, 8 patients (57.1%) developed acute respiratory distress syndrome (ARDS). 7 patients (50%) had underlying chronic respiratory disease and hepatic arteriovenous fistula was detected in 6 patients (42.6%), both of which were significantly higher than control group (P<0.05). Dyspnea (92.9%) was the most common symptoms. Pleural effusion (64.3%), diffuse pulmonary infiltration (42.9%), and accumulation of Lipiodol in lung field (42.9%) were frequent radiologic abnormalities. 11 patients (78.6%) achieved remission after treatment, and the 30-day mortality rate was approximately 21.4%. Patient's median survival time after the development of ALI was merely 4.3 months, which was obviously worse than control group (4.3 months vs. 13.5 months, P<0.05). Conclusion. This study illustrates that TACE-associated ALI is a rare pulmonary complication with a high mortality rate. We infer that pulmonary Lipiodol embolization might be one of the main causes of TACE-associated ALI. Thus, HCC patients who are at high risk should be closely evaluated and monitored during TACE to avoid such potentially fatal complication. [ABSTRACT FROM AUTHOR]

Coccolithophores are cosmopolitan, major calcifying protists that have significant roles in marine carbon cycling. Although the influence of temperature and irradiance fluctuation on coccolithophore physiology have been extensively studied, little is known about these effects on coastal coccolithophore species, including their cell morphology, coccolith formation, life cycle, and photoacclimation. We carried out indoor experiments to investigate the photo-physiological response of Chrysotila dentata at two temperatures (13 °C and 25 °C) and varied light irradiance. Using a geometric model, coccolith volume and mass of C. dentata were estimated. At low temperature (13 °C) and low irradiance (100 μmol photons m−2 s−1) cell size and coccolith calcite mass increased, which was further verified using a geometric model. The ratio of calcification to total carbon fixation rate and certain pigments (chlorophyll a, fucoxanthin and β-carotene concentrations) increased at high temperature (25 °C). Cells had variable C and N quotas (apparent diel cycling of C:N ratio) when cells were forming new coccoliths. Our findings help to better understand environmental controls on coccolith carbonate production and interaction with organic carbon production in C. dentata. [ABSTRACT FROM AUTHOR]

The Yangtze River, which is the largest in Euro-Asian, receives tremendous anthropogenic nitrogen input and is typically characterized by severe eutrophication and hypoxia. Two major processes, denitrification and anaerobic ammonium oxidation (anammox), play vital roles for removing nitrogen global in nitrogen cycling. In the current study, sediment samples were collected from both latitudinal and longitudinal transects along the coastal Yangtze River and the East China Sea (ECS). We investigated community composition and distributions of nos Z gene-encoded denitrifiers by high throughput sequencing, and also quantified the relative abundances of both denitrifying and anammox bacteria by q-PCR analysis. Denitrifying communities showed distinct spatial distribution patterns that were impacted by physical (water current and river runoffs) and chemical (nutrient availability and organic content) processes. Both denitrifying and anammox bacteria contributed to the nitrogen removal in Yangtze Estuary and the adjacent ECS, and these two processes shifted from coastal to open ocean with reverse trends: the abundance of nos Z gene decreased from coastal to open ocean while anammox exhibited an increasing trend based on quantifications of hzs B and 16S rRNA genes. Further correspondence correlation analysis revealed that salinity and nutrients were the main factors in structuring composition and distribution of denitrifying and anammox bacteria. This study improved our understanding of dynamic processes in nitrogen removal from estuarine to open ocean. We hypothesize that denitrification is the major nitrogen removal pathway in estuaries, but in open oceans, low nutrient and organic matter concentrations restrict denitrification, thus increasing the importance of anammox as a nitrogen removal process. Image 1 • Both denitrifying and anammox bacteria contributed to the nitrogen removal in Yangtze Estuary and the adjacent ECS. • The abundance of nos Z gene decreased from coastal to open ocean. • The abundance of anammox bacteria increased from coastal to open ocean. • The distinct spatial distribution pattern of denitrifying bacteria was observed along environmental gradients. • The distribution patterns were impacted by both physical and chemical processes. [ABSTRACT FROM AUTHOR]

In order to rapidly and nondestructively identify tea grades, fluorescence hyperspectral imaging (FHSI) technology was proposed in this paper. A total of 309 Tieguanyin tea samples with three different grades were collected and the fluorescence hyperspectral data was acquired by hyperspectrometer (400 to 1000 nm). The characteristic wavelengths were respectively selected by Bootstrapping Soft Shrinkage (BOSS), Variable Iterative Space Shrinkage Approach (VISSA) and Model Adaptive Space Shrinkage (MASS) algorithms. Then, Support Vector Machine (SVM) was applied to establishing the relationship between the characteristic peaks, the full spectra, three characteristic spectra and the labels of tea grades. The results showed that VISSA‐SVM model had the best classification performance, but the model precision can still be improved. Thus, Artificial Bee Colony (ABC) algorithm was introduced to optimize the parameters of SVM model. The accuracy and Kappa coefficient of test set of VISSA‐ABC‐SVM model were improved to 97.436% and 0.962, respectively. Therefore, the combination of fluorescence hyperspectra with VISSA‐ABC‐SVM model can accurately identify the grade of Tieguanyin tea. Practical Application: The rapid and accurate nondestructive tea grade identification method contributes to the construction of the tea online grade detection system. FHSI technology can solve the shortcomings of the reported methods and improved the identification accuracy of tea grades. It can be applied to the rapid detection of tea quality by tea companies, tea market, tea farmers and other demanders. [ABSTRACT FROM AUTHOR]

Background: Many diseases have been associated with intestinal microbial dysbiosis. Host-microbial interactions regulate immune function, which influences the development of gastric cancer.Aims: The aims were to investigate the characteristics of intestinal microbiota composition in gastric cancer patients and correlations between the intestinal microbiota and cellular immunity.Methods: Fecal samples were collected from 116 gastric cancer patients and 88 healthy controls from Shanxi Province, China. The intestinal microbiota was investigated by 16S rRNA gene sequencing. Peripheral blood samples were also collected from the 66 gastric cancer patients and 46 healthy controls. The populations of peripheral T lymphocyte subpopulations and NK cells were analyzed by flow cytometry.Results: The intestinal microbiota in gastric cancer patients was characterized by increased species richness, decreased butyrate-producing bacteria, and the enrichment of other symbiotic bacteria, especially Lactobacillus, Escherichia, and Klebsiella. Lactobacillus and Lachnospira were key species in the network of gastric cancer-associated bacterial genera. The combination of the genera Lachnospira, Lactobacillus, Streptococcus, Veillonella, and Tyzzerella_3 showed good performance in distinguishing gastric cancer patients from healthy controls. There was no significant difference in enterotype distribution between healthy controls and gastric cancer patients. The percentage of CD3+ T cells was positively correlated with the abundance of Lactobacillus and Streptococcus, and CD3+ T cells, CD4+ T cells, and NK cells were associated with Lachnospiraceae taxa.Conclusions: Our study revealed a dysbiotic intestinal microbiota in gastric cancer patients. The abundance of some intestinal bacterial genera was correlated with the population of peripheral immune cells. [ABSTRACT FROM AUTHOR]

Abstract Despite strong governmental support, microalgae biodiesel has failed to report rapid growth in China. Thus, it is imperative to conduct an economic analysis on microalgae biodiesel so that useful inputs could be provided for policy making. The analysis is based on a model with a 100-ha production facility. In addition, a sensitivity analysis is performed in this study to determine critical factors contributing to the economic feasibility of microalgae biodiesel. Furthermore, a learning curve is employed to predict the production cost from 2019 to 2022. The production cost is estimated as USD 2.29/kg, which is significantly higher than that of commercial diesel. The findings highlight that biodiesel projects lack economic feasibility and the main barriers are microalgae productivity, annual operating days and product benefits. According to the learning curve prediction, these issues cannot be alleviated within a short period, particularly considering the limitations associated with the current policies. The study concludes with policy implications e.g. a policy system to facilitate the development of microalgae biodiesel. Graphical abstract fx1 Highlights • Conducts economic analysis of China's microalgae biodiesel industry. • Performs sensitivity analysis to determine factors affecting economic feasibility. • Employs learning curve to predict production cost for the next five years. • Microalgae productivity, annual operating days, and product benefits are barriers. • Recommends policy system to facilitate the development of microalgae biodiesel. [ABSTRACT FROM AUTHOR]

The influence of typhoon and Kuroshio intrusion process on the natural phytoplankton assemblages in the northeastern South China Sea (neSCS) was examined during a cruise in summer 2017. One hundred ninety-six seawater samples were collected and analyzed in the neSCS. In total, 299 species were identified belonging to 82 genera, mostly dominated by Bacillariophyta (159), followed by Dinophyta (132), Cyanophyta (4) and Chrysophyta (4). Among all, Thalassionema nitzschioides, Thalassionema frauenfeldii, Thalassiosira minima, in Bacillariophyta, Prorocentrum lenticulatum, Prorocentrum compressum in Dinophyta, and Trichodesmium thiebautii, in the Cyanophyta were the most dominated species, respectively. Correlation analysis shows compared with other groups Bacillariophyta was mostly influenced by silicate, whereas, Dinophyta and Cyanophyta showed significant correlation with temperature, salinity, phosphate, and nitrate. After the typhoon, the higher abundance of Dinophyta was observed, whereas it was lower in case of Bacillariophyta and Cyanophyta, shows typhoon "Roke" and "Haitang" had a significant influence on the phytoplankton assemblages, which could be manifested by the variations of total phytoplankton abundance in the surface water of neSCS. Overall, our present study provides the latest in-depth information about how the environmental factors influencing the phytoplankton density and diversity in the neSCS during summer. [ABSTRACT FROM AUTHOR]

Climate warming has increased the frequency of droughts and excessive precipitation, adversely affecting crop growth, particularly under traditional intensive tillage. No-till improves crop tolerance to extreme events by reducing soil evaporation and improving soil structural stability to enhance soil water storage capacity and crop resistance, but long-term mono-no-till cakes the soil, reducing crop yield. Combining intensive tillage with no-till can compensate for some deficiencies arising from conventional tillage or single no-till. A three-year field experiment was conducted in wet (2020) and normal (2019 and 2021, where a drought event occurred in 2021) years to study the effect of tillage practices on summer maize productivity under different precipitation types. Treatments included conventional tillage (CT), no-tillage (NT), ridge cultivation with no-tillage (RNT), and conventional tillage of winter wheat combined with no-tillage of summer maize (NC). Compared with NT, NC and RNT significantly reduced soil bulk density and increased soil porosity in the 0–20 cm soil layer. Compared with CT, NC and RNT significantly improved aggregate stability, NC increased available soil water storage by 19.7% in the dry season (P < 0.05), and NC and RNT significantly reduced lodging rate in the rainy season. Over the three years, NC and RNT maintained higher maize yields (NC: 10.3 t ha–1 and RNT: 10.0 t ha–1) than CT (9.2 t ha–1), and NC had significantly higher yield stability than CT. Meanwhile, NC and RNT had higher precipitation use efficiency (PUE; NC: 21.2 kg ha–1 mm–1, RNT: 20.7 kg ha–1 mm–1) than NT (20.1 kg ha–1 mm–1) or CT (19.1 kg ha–1 mm–1). In terms of combined productivity, NC and RNT provide a more suitable soil environment for crop growth and maintain higher yield than NT and CT. NC rotation is recommended as the optimal tillage system for sustainable crop production under semi - arid agricultural conditions. RNT can be extended to areas prone to flooding with abundant rainfall. These results offer a benchmark for future studies on regional maize production under climate change. • The effect of tillage on maize productivity under abnormal precipitation conditions was analyzed. • Combined tillage effectively reduces the risk of crop failure due to seasonal drought or flooding. • The high yield is due to higher water use efficiency in the dry season and higher resistance to lodging in the wet season. • No-tillage and conventional tillage rotation tillage（NC） is suitable for maize production in most areas. • Ridge cultivation with no-tillage (RNT) is suitable for areas with abundant precipitation. [ABSTRACT FROM AUTHOR]

During the diversity assessment of marine nematodes in the China seas, a new species of Oxyonchus (Filipjev, 1927) De Coninck & Schuurmans Stekhoven 1933 was discovered from the Yellow Sea of China. O. boucheri sp. nov. is characterized by cuticle smooth; mouth opening surrounded by three lips separated by deep clefts; cephalic region with developed cephalic capsule; mandibles arch-shaped, rods linked with anteriorly transverse bar, two subventral teeth extend to the mandibles' anterior ends; thick outer and inner labial setae; six files of 2–4 cervical setae; conico-cylindrical tail without terminal seta; curved spicules with tapered distal ends; gubernaculum with dorso-caudal apophysis; a ventral tubular and 6–8 pairs subventral spinous precloacal supplements. The new species differs from other 17 congeners mainly in its conical inner and thick outer labial setae (vs. slender labial setae), files of 2–4 cervical setae present (vs. cervical setae absent), slender spicules with tapered distal ends (vs. spicules with capitulum), both ventral tubular and subventral spinous precloacal supplements (vs. only tubular supplement in males). Updated dichotomous key to the genus Oxyonchus were provided. • One new nematode species have been described from the Yellow Sea of China. • This study enriched the species diversity of nematodes in Chinese sea area. • The updated key for valid species of Oxyonchus has been provided. [ABSTRACT FROM AUTHOR]

Input capacity constraints means a firm cannot make its output decision based on the first - order optimal condition of profit maximization because it does not have enough inputs. Input capacity constraints have a significant effect on production quality and firm competition, especially on food safety management. This paper tries to provide a new perspective for quality operation in supply chain management. It also designs a new mechanism for quality regulation. After distinguishing between quantity-sensitive input capacity constraints and quality-sensitive input capacity constraints, this paper demonstrates a theoretical analysis about the impact of input capacity constraints on food quality and quality regulation by game theory. The results show that both kinds of capacity input constraints lead to a lower level of output, quality and consumer surplus, but a higher level of prices. In this study, we design a quality regulation to stimulate the growth of high quality food products. More importantly, this paper proves that reward is more effective in food quality guarantee programs than punishment or fine based programs. The conclusions are helpful for addressing food safety problems for both the supervisors and firms. [ABSTRACT FROM AUTHOR]

Mobile payment is becoming increasingly popular, but it encounters the resistance from certain user groups. This study examines the factors that influence both the technology acceptance and actual usage aspects of mobile payment adoption from the perspective of the general systems theory. Based on a literature review, it conceptualizes the embedding relationships among relevant behavioral processes, personal characteristics, and extrinsic factors and develops a research model. Together, the extrinsic factors in terms of culture, subjective norm, and socioeconomic status and main personal characteristics including demographics, personality traits, and past behavior are hypothesized to have direct and moderating effects on mobile payment acceptance and usage. The observations collected from China and the USA support most of the hypothesized relationships and reveal interesting cross-culture differences. Whereas users in the USA appear to be more rational and risk-averse, people in China seem more subject to social influence. The findings contribute to the mobile payment literature by deepening the understanding of adoption stages and expanding the scope of explanatory variables beyond technology acceptance. [ABSTRACT FROM AUTHOR]