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As a main carrier mode for the sustainable development of the construction industry in China, prefabricated building may lead to problems such as cost overruns, project delays, and waste of resources due to unreasonable selection of prefabricated components. Therefore, we quantitatively analyze the contribution rate of quality optimization of prefabricated components using QFD-SEM. Under the constraints of prefabrication rate, quality optimization contribution rate, and expected values of various sub-goals, we propose a multi-objective optimization method for prefabricated component combinations based on cost, duration, and carbon emissions. By using NSGA-II to solve the model, we can obtain a set of optimal Pareto solutions for prefabricated component combinations. Based on the optimal Pareto solution set, we establish a multi-objective evaluation model using simulated annealing optimization projection tracing method, and select the optimal prefabricated component combination solution according to the projected eigenvalues of the solutions. An empirical study is conducted using an eleven-story framed building in Shenzhen, Guangdong Province, China as a case study. The results show that: (1) Using this method, optimal solutions can be obtained in an unbounded solution space, with the optimal solution having advantages over both fully cast-in-place and fully prefabricated solutions. Compared to the fully cast-in-place solution, the duration and carbon emissions are reduced by 36.62% and 12.74% respectively, while compared to the fully prefabricated solution, costs are reduced by 4.15%. (2) There is a certain negative correlation between the cost of prefabricated component combinations and duration, carbon emissions, and quality optimization, while there is a certain positive correlation with the prefabrication rate. (3) The size of the optimal projection direction vector based on the optimization objectives indicates that carbon emissions have the greatest impact on the evaluation results of the solutions. [ABSTRACT FROM AUTHOR]

Zhuke-Hulu tea is an herbal tea widely enjoyed by people in Southern China. For the first time the phytochemical compositions of Zhuke-Hulu tea ethanol extract (ZHTE) were analyzed by GC-MS and UPLC-ESI-MS/MS, and the anti-oxidant and anti-inflammatory activities were evaluated. Several categories of substances in ZHTE were identified, among which organic acids, phenolics/phenolic acids and flavonoids were the major components. ZHTE showed significant anti-oxidant activity as measured by free radical scavenging assays and reducing power test. Moreover, ZHTE exhibited cytoprotective effect against H 2 O 2 -induced oxidative stress damage by enhancing endogenous anti-oxidant defense system and Nrf2 nuclear translocation. In addition, ZHTE also exerted anti-inflammatory efficiency by down-regulating the protein levels of iNOS and COX-2 as well as the production of pro-inflammatory cytokines. In parallel, ZHTE alleviated intestinal inflammation induced by dextran sulfate sodium (DSS) through reducing pro-inflammatory cytokines level, inhibiting inflammatory cell infiltration, and modulating gut microbiota. These findings provide a solid foundation for the nutraceutical benefits of Zhuke-Hulu tea and promote its consumption as a functional beverage. [Display omitted] • Phytochemical profile of Zhuke-hulu tea ethanol extract (ZHTE) was firstly analyzed. • Organic acids, polyphenols and flavonoids were the major components of ZHTE. • ZHTE showed significant anti-oxidant and anti-inflammatory activities. • ZHTE showed remarkable cytoprotective effect against oxidative stress damage. • Anti-colitis effect of ZHTE was related to the regulation of gut microorganisms. [ABSTRACT FROM AUTHOR]