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Copyright of Comunicar (English Edition) is the property of Oxbridge Publishing House and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Comunicar (English Edition) is the property of Oxbridge Publishing House and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This letter examines the impact of risk preference and social insurance on household financial market participation and diversification using the 2017 and 2019 China Household Finance Survey. A multi-value treatment model addresses the selection bias between risk preference and household financial investment, considering the moderation role of social insurance in between. Overall, our results show that high-risk takers are more likely to participate in the financial market and diversify their portfolios than low-risk takers. Focusing on rural and urban differentials, we find marked differences in the impacts of risk preference and social insurance on household financial investment. Having social insurance may widen the difference in investment decisions between high- and low-risk takers in urban areas; the latter group tends not to participate in or diversify when socially insured. In contrast, having social insurance encourages low- and intermediate-risk preferred rural households to participate in the financial market and diversify their financial portfolios. Our work highlights the different consequences of social insurance on investment incentives for rural and urban households. Whilst there are obvious benefits of having social insurance for rural households via risk-sharing, there is an undesired consequence of incentive distortion of urban households. [ABSTRACT FROM AUTHOR]

BACKGROUND Previous studies have suggested that a single dose of rifampin has protective effects against leprosy in close contacts of patients with the disease. Rifapentine was shown to have greater bactericidal activity against Mycobacterium leprae than rifampin in Inurine models of leprosy, but data regarding itS effectiveness in preventing leprosy are lacking. METHODS We conducted a cluster-randomized, controlled trial to investigate whether single-dose rifapentine is effective in preventing leprosy in household contacts of patients with leprosy. The clusters (counties or districts in Southwest China) were assigned conto one of three trial groups: single-dose rifapentine, single-dose rifampin, or con. trol (no intervention). The primary outcome was the 4-year cumulative incidence of leprosy among household contacts. RESULTS A total of 207 clusters comprising 7450 household contacts underwent randomization; 68 clusters (2331 household contacts) were assigned to the rifapentine group, 71 (2760) to the rifampin group, and 68 (2359) to the control group. A total of 24 new cases of leprosy occurred over the 4-year follow-up, for a cumulative incidence of 0.09% (9596 confidence interval [CI], 0.02 to 0.34) with rifapentine (2 cases), 0.33% (95% CI, 0.17 to 0.63) with rifampin (9 cases), and 0.55% (95% CI, 0.32 to 1.95) with no intervention (13 cases). In an intention-to-treat analysis, the cumulative incidence in the rifapentine group was 84% lower than that in the control group (cumulative incidence ratio, 0.16; multiplicity-adjusted 95% CI, 0.03 to 0.87; P=0.02); the cumulative incidence did not differ significantly between the rifampin group and the control group (cumulative incidence ratio, 0.59; multiplicityadjusted 95% CI, 0.22 to 1.57; P=O.23). In a per-protocol analysis, the cumulative incidence was 0.05% with rifapentine, 0.19% with rifampin, and 0.63% with no intervention. No severe adverse events were observed. CONCLUSIONS The incidence of leprosy among household contacts over 4 years was lower with single-dose rifapentine than with no intervention. (Funded by the Ministry of Health of China and the Chinese Academy of Medical Sciences; Chinese Clinical Trial Registry number, ChiCTR-IPR-15007075.). [ABSTRACT FROM AUTHOR]

We investigated a case of cutaneous infection in an immunocompromised patient in China that was caused by a novel species within the Mycobacterium gordonae complex. Results of whole-genome sequencing indicated that some strains considered to be M. gordonae complex are actually polyphyletic and should be designated as closely related species. [ABSTRACT FROM AUTHOR]

The land–atmosphere interaction has been considered one of the most important part for weather prediction and climate modeling. To evaluate the uncertainty coming from land surface models (LSMs) and land use (LU) data in WRF simulated climatology over China, we have conducted fifteen 10-year simulations from 1996 to 2005 with three LSMs (NOAH, CLM and RUC) and five LU data sets (MODIS, HYDE, HH, RF and CESM). Compared to the MODIS, the most major differences for HYDE, HH and RF include the reduction of the barren or sparsely vegetated area and the CESM map shows the largest arid and semi-arid area. Based on performance evaluation of WRF model, the uncertainties of LSMs and LU data are analyzed in a three-dimension aspect: the magnitudes of response, spatial and temporal patterns. The impact of LSM and LU data is statistically significant in some regions and the LSM effect is substantially higher than the LU data especially for precipitation. The temporal effect of combinations of LSM and LU data varied across regions. For temperature, we find that the effects of LSMs and LU data on the spatial pattern and magnitude are one order smaller than those on temporal pattern, and the uncertainties from LSMs and LU datasets are as the same order when considering the temporal and spatial patterns. The results also indicate that the uncertainty of LU data on precipitation is much smaller than that of LSMs on magnitude and spatial patterns. These findings reflect that the relative importance of LSMs and LU data in the WRF climate modeling largely depends on the specific LSM. [ABSTRACT FROM AUTHOR]

The service areas of the BeiDou Navigation Satellite System (BDS) are China, the Asia–Pacific, and the world via three stages of development. The BDS constellation is designed to maintain a geostationary Earth orbit (GEO), inclined geosynchronous orbit (IGSO), and medium Earth orbit (MEO). These orbital maneuvers yield certain difficulties for data processing, especially for the BeiDou satellites, such as a decrease in the real-time service performance, which causes a missing precise orbit product from the maneuvered satellites. The frequencies of the orbital maneuvers for the GEO and IGSO satellites are higher than those for the MEO satellites. The maneuvering time and strategy cannot be obtained by common users due to secrecy, which can yield a decline in the service performance of the BDS. Thus, in this study, we analyzed the variation in the orbital semimajor axis for the satellites. The long-term variation in the orbital semimajor axis changes linearly. The short-term variation in the orbital semimajor axis also has periodicity, which can be described by the sum of sine functions. According to the long-term variation in the orbital semimajor axis for the satellites, we propose a detection method for in-plane orbital maneuvering of the GEO, IGSO, and MEO satellites. We then propose a detection method for out-of-plane maneuvering of the GEO satellites. BDS and Global Positioning System (GPS) data from the broadcast ephemeris were analyzed to verify the proposed methods. The experimental results from 2013 to 2019 show that the frequency of orbital maneuvering is approximately once a month for the GEO satellites, once every six months for the IGSO satellites, and once every 1.4 years for the MEO satellites. [ABSTRACT FROM AUTHOR]

An effective system for monitoring, reporting and verification (MRV) is the cornerstone of any carbon emissions trading market. This paper analyses existing MRV frameworks in China, including under the seven emission trading pilot schemes, to identify four key challenges for the establishment of an effective MRV system for China's forthcoming national carbon emissions trading market: (1) ambiguity in the legal status of relevant policies and regulations, (2) unclear requirements for the content of monitoring plans, (3) lack of consistency and harmonization in accounting and reporting guidelines, and (4) lack of information technology (IT). The paper then considers the experiences and lessons of the European Union Emissions Trading Scheme (EU-ETS) and the MRV systems in the seven carbon emissions trading pilots, and puts forward suggestions for tackling the four key challenges. [ABSTRACT FROM AUTHOR]

Background: The reliability of bilirubin measurements is not satisfactory due to the marked variability of methodologies since discovery. Methods: Imprecision of the three analytical systems (diazo method, vanadate oxidase method, and dry chemistry method) were calculated in accordance with CLSI guidelines EP15-A2. According to Clinical and Laboratory Standards Institute (CLSI) guideline (EP9-A2), 40 analytes were detected to evaluate method performance and comparability among three routine measurements for serum bilirubin in a China laboratory. Results: The within-run precisions and the intermediate imprecision of the three methods all met the CLIA'88 requirement of bilirubin measurement. All three evaluated methods were closely correlated with correlation coefficients ranging from 0.995 to 0.999. The 95% predicted bias confidence intervals between diazo method and vanadate oxidase method for total bilirubin were acceptable. However, for direct bilirubin, the 95% predicted bias confidence intervals was only acceptable at the medium medical decision point. The 95% predicted bias confidence intervals between diazo method and dry medical method for total bilirubin was all acceptable. Conclusions: All three evaluated routine methods for serum bilirubin in our lab were closely correlated. For measurements of total and direct bilirubin, both dry medical method and vanadate oxidase method had significant differences compared with the diazo method. Further studies are required to reduce the biases among these methods. [ABSTRACT FROM AUTHOR]

Background and objective Lung cancer is the most common malignancy and screening can decrease the mortality. High quality screening guideline is necessary and important for effective work. Our study is to review and evaluate the basic characteristics and methodology quality of the current global lung cancer screening guidelines so as to provide useful information for domestic study in the future. Methods Electronic searches were done in English and Chinese databases including PubMed, the Cochrane Library, Web of Science, Embase, CNKI, CBM, Wanfang, and some cancer ofcial websites. Articles were screened according to the predefned inclusion and exclusion criteria by two researchers. The quality of guidelines was assessed by AGREE II. Results At last, a total of 11 guidelines with methodology were included. The guidelines were issued mainly by USA (81%). Canada and China developed one, respectively. As for quality, the average score in the "Scale and objective" of all guidelines was 80, the average score in the "Participants" was 52, the average score in the "rigorism" was 50, the average score in the "clarity" was 76, the average score in the "application" was 43 and the average score in the "independence" was 59. The highest average score was found in 2013 and 2015. Canada guideline had higher quality in six domains. 7 guidelines were evaluated as A level. Conclusion The number of clinical guidelines showed an increasing trend. Most guidelines were issued by developed countries with heavy burden. Multi-country contribution to one guideline was another trend. Evidence-based methodology was accepted globally in the guideline development. [ABSTRACT FROM AUTHOR]

The large yellow croaker (Larimichthys crocea) is the most important mariculture fish species in China and the wild stocks of this croaker have collapsed in the past decades due to high fishing pressure and habitat degradation. Due to a lack of wild croaker samples, however, studies concerning the genetic changes of the cultured croaker stocks compared to their wild counterparts were never conducted. Here, we collected three wild populations in the northern and central East China Sea during fisheries survey and investigated the differences in terms of genetic diversity and differentiation between and within cultured stocks and wild populations. Our results demonstrated that the cultured croaker had significantly reduced genetic diversity in contrast to the wild populations, and also presented statistically significant differentiation from the wild, indicating that enhancement of the current wild stock should be conducted with caution. These changes may be caused by founder effects, artificial selection and random genetic drift. With a relatively high level of genetic diversity, the wild populations showed important value for improving the ongoing breeding program of this croaker. Further, we detected no differentiation among the wild populations, suggesting that the wild croaker in the northern and central East China Sea should be considered as one unit for management and conservation. [ABSTRACT FROM AUTHOR]

In this paper, we propose a new concept of convergence which is based on the metric entropy measure recently proposed by Granger et al. (2004, Journal of Time Series Analysis 25, 649–69) to investigate economic convergence in China. This entropy measure compares whole distributions of growth rates across individual provinces. Separately, based on this same entropy measure, we also implement cluster analysis to identify any convergence clubs. Our four main conclusions are: (1) while we certainly reject the null hypothesis that there exists a nationwide convergence, we do find that there exist convergence clubs for both the pre- and post-reform periods, (2) we find a number of very small convergence clubs. In particular, there are eleven and six convergence clubs for the pre- and post-reform periods, respectively, (3) in comparing the number and size of convergence clubs for both the pre- and post-reform periods, it could be argued that the extent of convergence is more prevalent during the post-reform period than during the pre-reform period and (4) convergence groups cannot be simply characterized by such unique features as region or the extent of policy preference level that are commonly used in the literature. [ABSTRACT FROM AUTHOR]

We compare several income distributions in urban China in the late 1980s and mid-1990s using tests for stochastic dominance in order to decompose gender differentials. Examination of the entire distribution gives insight into the uniformity of such differentials across the distribution. Moreover, tests based on stochastic dominance allow for robust welfare comparisons. Our analysis reveals: (i) large and increasing differentials in predicted earnings across gender in the lower tail of the distribution, but few differences in the upper tail, (ii) discrimination explains one-third to one-half of the total predicted earnings differential in the lower tail of the distribution, and little of the disparity in the upper tail, (iii) gender equity has eroded during China's economic transition, particularly for the youngest cohort, and (iv) significant nonuniformities in earnings differentials suggest the need to broaden analyses of gender differentials to incorporate earnings dispersion. [ABSTRACT FROM AUTHOR]

With the rapid increase of GPS/GNSS receivers being deployed and operated in China, real-time GPS data from nearly a thousand sites are available at the National Center for Space Weather, China Meteorology Administration. However, it is challenging to generate a high-quality regional total electron content (TEC) map with the traditional two-dimensional (2-D) retrieval scheme because a large horizontal gradient has been reported over east-south Asia due to the northern equatorial ionization anomaly. We developed an Ionosphere Data Assimilation Analysis System (IDAAS), which is described in this study, using an International Reference Ionosphere (IRI) model as the background and applying a Kalman filter for updated observations. The IDAAS can reconstruct a three-dimensional ionosphere with the GPS slant TEC. The inverse slant TEC correlates well with observations both for GPS sites involved in the reconstruction and sites that are not involved. Based on the IDAAS, simulations were performed to investigate the deviation relative to the slant-to-vertical conversion (STV). The results indicate that the relative deviation induced by slant-to-vertical conversion may be significant in certain instances, and the deviation varies from 0% to 40% when the elevation decreases from 90° to 15°, while the relative IDAAS deviation is much smaller and varies from -5% to 15% without an elevation dependence. Compared with 'true TEC' map derived from the model, there is large difference in STV TEC map but no obvious discrepancy in IDAAS map. Generally, the IDAAS TEC map is much closer to the "true TEC" than is STV TEC map is. It is suggested that three-dimensional inversion technique is necessary for GPS observations of low elevation at an equatorial anomaly region, wherein the high horizontal electron density gradient may produce significant slant-to-vertical deviations using the two-dimensional STV inversion method. [ABSTRACT FROM AUTHOR]

Many fruit flies in the genus Bactrocera (Diptera: Tephritidae: Dacini) are economically important insects. However, little attention has been given to the molecular phylogenetic relationship among Bactrocera subgenera. We explored the phylogenetic relationship among the 8 subgenera Afrodacus, Austrodacus, Bactrocera, Daculus, Gymnodacus, Paratridacus, Tetradacus, and Zeugodacus based on the sequences of 2 mitochondrial DNA fragments with a combined length of 1034 base pairs. The 2 mtDNA fragments are a 689-bp segment of the COI gene and a 345- bp segment of the 16S rDNA gene. Thirty-five individuals representing 7 Bactrocera species found in the Chongqing region in China were sequenced for both fragments, and sequences of the same gene regions were acquired from GenBank for another 20 Bactrocera species and 2 other tephritid species, Anastrepha ludens and Ceratitis capitata, which were used as outgroups for the phylogenetic analyses. We reported Bactrocera ( Tetradacus ) minax and Bactrocera ( Zeugodacus ) diaphora sequences for the first time, and the subgenus Bactrocera ( Tetradacus ), here represented by B. ( T. ) minax and B. ( T. ) tsuneonis, was included for the first time in an analysis of the genus Bactrocera phylogeny. Results of our analyses showed withinsubgenus nucleotide diversity ranged from 9.1 to 19.0% among the subgenera, and the net divergence among subgenera ranged from 4.6 to 12.7%. Results of phylogenetic analyses based on maximum parsimony method supported that subgenus Bactrocera ( Bactrocera ) and Bactrocera ( Zeugodacus ) are paraphyletic. The subgenus Zeugodacus, Bactrocera ( Zeugodacus ) caudate, Bactrocera ( Zeugodacus ) diaphora, and Bactrocera ( Zeugodacus ) scutellata are closely related to Bactrocera ( Zeugodacus ) tau and Bactrocera ( Zeugodacus ) cucurbitae . This results indicated that subgenus Austrodacus and Zeugodacus, which attack cucurbit plants, are closely related to species of the subgenus Afrodacus, Bactrocera, and Gymnodacus, which attack plants of numerous families. In addition, subgenus Paratridacus is a sister group to subgenus Tetradacus, and 7 species of the Bactrocera ( Bactrocera ) dorsalis complex (as defined by Drew & Hancock 1994) included in this study formed a monophyletic clade. Subgenus Daculus is 1lineage by itself, which does not fall into the Bactrocera group or Zeugodacus group. [ABSTRACT FROM AUTHOR]

A total of 58 (eight known and 50 new) species of the subgenus Stegana (Steganina) from China were surveyed and (re)described: S. (S.) bacilla Chen & Aotsuka, 2004, S. (S.) belokobylskiji Sidorenko, 1997, S. (S.) hirticeps Wang, Gao, & Chen, 2013, S. (S.) izu Sidorenko, 1997, S. (S.) kanmiyai Okada & Sidorenko, 1992, S. (S.) masanoritodai Okada & Sidorenko, 1992, S. (S.) maymyo Sidorenko, 1997, stat. rev., S. (S.) nigripes Zhang & Chen, 2015, S. (S.) alafoliacea Zhang & Chen, sp. nov., S. (S.) baoxing Li & Chen, sp. nov., S. (S.) bibarbata Li & Chen, sp. nov., S. (S.) bimai Cui & Chen, sp. nov., S. (S.) cinereipecta Zhang & Chen, sp. nov., S. (S.) cardua Cui & Chen, sp. nov., S. (S.) cordhirsuta Wang & Chen, sp. nov., S. (S.) cornuta Li & Chen, sp. nov., S. (S.) cucullata Li & Chen, sp. nov., S. (S.) cultella Cui & Chen, sp. nov., S. (S.) curvitabulata Cui & Chen, sp. nov., S. (S.) daiya Cui & Chen, sp. nov., S. (S.) dendrophila Zhang & Chen, sp. nov., S. (S.) flabella Li & Chen, sp. nov., S. (S.) flavipes Li & Chen, sp. nov., S. (S.) formosa Zhang & Chen, sp. nov., S. (S.) fusca Li & Chen, sp. nov., S. (S.) fuscipes Li & Chen, sp. nov., S. (S.) glaucopalpula Cui & Chen, sp. nov., S. (S.) haba Zhang & Chen, sp. nov., S. (S.) hirticlavata Cui & Chen, sp. nov., S. (S.) iaspidea Zhang & Chen, sp. nov., S. (S.) idiasta Cui & Chen, sp. nov., S. (S.) kanda Cui & Chen, sp. nov., S. (S.) labao Li & Chen, sp. nov., S. (S.) lancang Li & Chen, sp. nov., S. (S.) latifoliacea Wang & Chen, sp. nov., S. (S.) liusanjieae Li & Chen, sp. nov., S. (S.) magniflava Cui & Chen, sp. nov., S. (S.) mailangang Li & Chen, sp. nov., S. (S.) marenubila Cui & Chen, sp. nov., S. (S.) menghai Zhang & Chen, sp. nov., S. (S.) menglian Li & Chen, sp. nov., S. (S.) minutiflava Li & Chen, sp. nov., S. (S.) multiprocera Li & Chen, sp. nov., S. (S.) nayun Li & Chen, sp. nov., S. (S.) nigridentata Wang & Chen, sp. nov., S. (S.) nigripalpula Cui & Chen, sp. nov., S. (S.) otphylla Cui & Chen, sp. nov., S. (S.) radiciflava Zhang & Chen, sp. nov., S. (S.) rava Cui & Chen, sp. nov., S. (S.) sciophila Li & Chen, sp. nov., S. (S.) septencolorata Li & Chen, sp. nov., S. (S.) serrata Zhang & Chen, sp. nov., S. (S.) silvestrella Zhang & Chen, sp. nov., S. (S.) simola Cui & Chen, sp. nov., S. (S.) yani Li & Chen, sp. nov., S. (S.) yixiang Zhang & Chen, sp. nov., S. (S.) zaduo Cui & Chen, sp. nov., and S. (S.) zhuoma Cui & Chen, sp. nov. We also provided a complete list of Chinese Steganina species together with their geographical distributions. In addition, the majority of currently available DNA barcode (partial sequence of the mitochondrial cytochrome c oxidase subunit I (COI) gene) sequences of this subgenus (435 sequences of 102 spp.) were employed in a molecular analysis for species delimitation. Taken together, morphology- and molecular-based species delimitation results reached a consensus for an overwhelming majority of these Steganina species (98 of 102 spp.).

Conflict management in PAs (Protected Areas) is becoming increasingly important in the context of the rapid development of nature-based tourism. Literature proposes the Index of Conflict tendency between Tourism development and ecological Protection (ICTP) to analyze the tendency of conflict from a spatial perspective, but this index does not consider the factor of seasonality which is important in tourism. The current study considers seasonality and proposes the CVD (Coverage- Variation- Duration) framework to conduct a spatio-temporal analysis of the ICTP. The applied research based on the case of China's V-PAs (a specific category of PAs) reflects that the CVD framework can describe the spatial distribution of the ICTP from a seasonal perspective. The study finds that, among V-PAs in China, 42.16% of the areas with high ICTP of V-PAs have obvious seasonal variations, which shows that PAs conflict management must incorporate the factor of seasonality. The study also shows that 8.98% of V-PAs have large-scale coverage of areas with high ICTP, revealing priorities for conflict management. 3.96% of V-PAs have large-scale coverage of areas with high ICTP showing seasonal changes. Management in these areas should pay attention to seasonal changes to become more effective. The CVD framework proposed in this paper is operable and extendable and can provide analytical tools for PAs conflict management, and promote ecological protection and more sustainable tourism development in PAs., (Copyright © 2021 Elsevier Ltd. All rights reserved.)

Increasing hotel/restaurant/café (HORECA) food consumption (HFC) has become one of the most prominent features of food consumption transformation under the background of rapid urbanization in China. Combining direct-weighing data (using 11,883 dishes in 164 restaurants) and literature data, this study, for the first time, quantitatively calculated the amount of HFC and its ecological footprint (EF) in China in 2002 and 2015 to depict the environmental effects of this transformation. The results indicated that per capita HFC tripled from 320 g/cap/meal in 2002 to 852 g/cap/meal in 2015, representing an average annual growth rate of 13%. In addition, by scaling up the HFC in 31 provinces/municipalities/autonomous regions to the national scale, HFC in China increased by 12,612 tons from 2002 to 2015. Finally, the total EF in the HORECA sector increased nearly 33 times (or 44,440 global ha), from 1348 global ha in 2002 to 45,788 global ha in 2015. The EF of Guangdong increased the most, surpassing 4000 global ha in 2015. These findings provide a scientific basis to support improved food resource spatial allocation and mitigation of regional resource pressure to achieve sustainable consumption under the current background of rapid urbanization in China., (Copyright © 2019 Elsevier B.V. All rights reserved.)

More than 100 counties, mainly in southwest China, report incidence rates of leprosy >1/100,000. The current study analysed the epidemiology of leprosy in southwest China to improve our understanding of the transmission pattern and improve control programs. 207 counties were selected in southwest China. Leprosy patients and their household contacts were recruited. The data from the medical interview and the serological antileprosy antibody of the leprosy patients were analysed. A total of 2,353 new cases of leprosy were interviewed. The distribution of leprosy patients was partly associated with local natural and economic conditions, especially several pocket areas. A total of 53 from 6643 household contacts developed leprosy, and the incidence rate of leprosy in the household contacts was 364/100,000 person-years. We found that NDO-BSA attained higher positive rates than MMP-II and LID-1 regardless of clinical types, disability and infection time in leprosy patients. By means of combination of antigens, 88.4% patients of multibacillary leprosy were detected, in contrast to 59.9% in paucibacillary leprosy. Household contacts should be given close attention for the early diagnosis, disruption of disease transmission and precise control. Applications of serology for multi-antigens were recommended for effective coverage and monitoring in leprosy control.

The ability to extract mitochondrial and nuclear DNA from ancient remains has enabled the study of ancient DNA, a legitimate field for over 20 years now. Recently, Y chromosome genotyping has begun to be applied to ancient DNA. The Y chromosome haplogroup in East Asia has since caught the attention of molecular anthropologists, as it is one of the most ethnic-related genetic markers of the region. In this paper, the Y chromosome haplogroup of DNA from ancient East Asians was examined, in order to genetically link them to modern populations. Fifty-six human remains were sampled from five archaeological sites, primarily along the Yangtze River. Strict criteria were followed to eliminate potential contamination. Five SNPs from the Y chromosome were successfully amplified from most of the samples, with at least 62.5% of the samples belonging to the O haplogroup, similar to the frequency for modern East Asian populations. A high frequency of O1 was found in Liangzhu Culture sites around the mouth of the Yangtze River, linking this culture to modern Austronesian and Daic populations. A rare haplogroup, O3d, was found at the Daxi site in the middle reaches of the Yangtze River, indicating that the Daxi people might be the ancestors of modern Hmong-Mien populations, which show only small traces of O3d today. Noticeable genetic segregation was observed among the prehistoric cultures, demonstrating the genetic foundation of the multiple origins of the Chinese Civilization.