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Introduction: Sexual assault is one of the most traumatic stressors one may experience in life. Although studies have investigated the prevalence of posttraumatic stress disorder (PTSD) and associated psychosocial factors on victims of sexual assault internationally, such studies in Mainland China are limited., Methods: Two hundred thirt-three Chinese females (aged 17-38) victims of sexual assault were surveyed in three Guangdong province cities (Guangzhou city, Shenzhen city, and Huizhou city). The Clinician-Administered PTSD Scale, Eysenck Personality Questionnaire, PTSD Checklist Civilian Version, Social Support Rating Scale, and Trait Coping Style Questionnaire were used., Results: The prevalence of PTSD in Chinese female victims of sexual assault was 15.25% (34/223). Six psychosocial factors were found to be significant for PTSD symptomatology, including objective support (β = -1.01, P = 0.001), subjective support (β = -0.59, P < 0.001), support utilization (β = -1.03, P = 0.005), negative coping style (β = 0.58, P < 0.001), positive coping style (β = -0.44, P < 0.001), and neuroticism (β = 0.48, P < 0.001)., Discussion: These findings suggest that negative coping bias and neuroticism were predisposing risk factors that increase PTSD symptoms, while objective support, subjective support, support utilization, and positive coping style were protective factors for PTSD following sexual assault, and provide prima facie evidence for posttrauma intervention., (© 2014 Wiley Publishing Asia Pty Ltd.)