1. DEVELOPMENT OF FORMULATION AND ASSESSMENT OF ANTIMICROBIAL POTENTIAL OF CALLISTEMON CITRINUS BARK EXTRACT.
- Author
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Singh, Abhishek, Dwivedi, Abhishek, Kumar, Abhishek, Singh, Vandana, Kumar, Satyender, and Sindhu, Rakesh K.
- Subjects
SAPONINS ,CALLISTEMON ,OINTMENTS ,EXTRACTS ,BACTERIAL diseases ,ANTI-infective agents - Abstract
The plant Callistemon citrinus have very wide history in medicinal uses in traditional medicinal systems in China and Australia. Formulation development and antimicrobial potential evaluation of Callistemon citrinus bark extract. In this research, ethanolic extract was prepare from dried bark using Soxhlet apparatus and phytochemical screening of the bark extract with the help of reagents. The ethanolic bark extract was used for formulation of cream and evaluated for physical, physiochemical and antimicrobial evaluation of herbal cream. The observation of phytochemical screening was found that different phytoconstituents were present like alkaloids, lipids, carbohydrates, saponins, flavonoids, and steroids etc. antimicrobial activity was significant, zone inhibition was increased with higher concentration of extract. The cream was formulated using different concentration of ethanolic extract. The pH of cream 6 to 6.8: texture is smooth: viscosity ranges b/w 27000 to 27050 cP and stable at physiochemical evaluation. In conclusion, on the basis of research conducted, it can be concluded that creams containing Callistemon citrinus extract with a good antibacterial property and it can be used for the treatment and management of topical infections like bacterial, fungal and viral. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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