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Purposes: Most adolescents worldwide do not meet 24‐h movement guidelines, which recommend specific level of physical activity, sedentary behavior, and sleep for optimal health. Nevertheless, there remains a lack of understanding regarding how social cognitive and physical environmental factors influence adolescents' compliance with these guidelines. This prospective study aimed to examine the associations between perceived physical environments, constructs of the theory of planned behavior (TPB), habit strength, and adherence to 24‐h movement guidelines in Chinese adolescents over a three‐month period. Methods: A total of 629 Chinese adolescents (Mage = 14.59 years, SD = 0.64) completed a set of questionnaires comprising perceived physical environmental characteristics, constructs of the TPB, habit strength, and 24‐h movement behaviors at baseline and 3 months later. Data analysis was conducted using variance‐based structural equation modeling. Results: Attitude, subjective norm, and perceived behavioral control had a direct effect on intention and intention had a direct effect on number of the guidelines being met. Habit strength was a significant predictor of adherence to the guidelines, although its moderating effect on the intention–behavior relationship was not significant. Perceived neighborhood facility accessibility, school facility availability, and home physical activity equipment had significant indirect effects on intention through attitude, subjective norm, and perceived behavioral control. However, constructs of the TPB did not serve as mediators in the relationship between perceived physical environments and the number of guidelines being met. Conclusion: This study offers preliminary evidence supporting the integration of perceived physical environments and the TPB in predicting adolescents' adherence to 24‐h movement guidelines. Future research should consider using experimental study designs with rigorous measures of 24‐h movement behaviors to establish causal relationships. [ABSTRACT FROM AUTHOR]

Most evidence regarding the relationships between adherence to 24-hour movement guidelines and adolescent mental health have been derived from cross-sectional studies or have ignored positive mental health indicators. The current prospective study examined the associations between adherence to 24-hour movement guidelines and changes in mental well-being among Chinese adolescents over three months. 816 Chinese adolescents (Mage = 14.76 years; SD = 0.81) completed baseline and follow-up scales of 24-hour movement behaviours, mental well-being, and covariates. Linear mixed-effects models were used for data analyses, with adjustments for covariates and mental well-being at baseline. There was a significant improvement in mental well-being across the three months, and the improvement in mental well-being was positively associated with meeting any single guidelines and both physical activity and sleep guidelines but not adherence to all three guidelines. Meeting both physical activity and sleep recommendations appears to exert more significant benefits on mental well-being than meeting one or two other recommendations. An integrative approach to mental health promotion by focusing on 24-hour movement behaviours (at least physical activity and sleep) may be more effective than focusing on a single behaviour alone. [ABSTRACT FROM AUTHOR]

To repair and protect ancient stone arch bridges from weathering, this paper proposed a comprehensive weathering prevention method. Based on the strategy of survey, diagnosis, analysis and therapy, the method consisted of four phases, including collecting digital records, performing weathering assessment, conducting laboratory analysis and choosing a conservation method, which could scientifically evaluate the weathering degree and provide a conservation method for stone arch bridges. The method was introduced via application to a typical ancient Chinese stone arch bridge, the Putang Bridge. Digital recording was mainly achieved through 3D scanning technology. Weathering assessment mainly depended on the weathering mapping method, and the analysis was divided considering the different parts of the bridge and the overall bridge, through which bridge weathering could be more precisely evaluated. Laboratory tests were conducted involving both weathered and fresh samples for degree comparison, including petrographic analysis, mercury intrusion porosimeter, X-ray diffraction and scanning electron microscopy. The conservation method was based on the optimum protective agent, and the tests of the protective agent included water absorption tests, durability tests, colour difference analysis tests and micro-mechanism observation tests. Finally, the bridge stones were determined as a type of tuff stone, the linear damage index of the overall bridge was 2.21, and the progressive damage index was 2.46. Regarding the different parts of the stone arch bridge, the most easily damaged parts included the balustrades, parapets, cutwater stones and foundations. After the tests, a type of oil-borne silicon- and resin-based protective agent was determined as the optimum one for this stone bridge. The research results could provide a scientific basis and operational guidance for weathering prevention of ancient stone arch bridges. [ABSTRACT FROM AUTHOR]

The aims of this study were to assess the cross-cultural invariance of athletes' self-reports of mental toughness and to introduce and illustrate the application of approximate measurement invariance using Bayesian estimation for sport and exercise psychology scholars. Athletes from Australia (n = 353, Mage = 19.13, SD = 3.27, men = 161), China (n = 254, Mage = 17.82, SD = 2.28, men = 138), and Malaysia (n = 341, Mage = 19.13, SD = 3.27, men = 200) provided a cross-sectional snapshot of their mental toughness. The cross-cultural invariance of the mental toughness inventory in terms of (a) the factor structure (configural invariance), (b) factor loadings (metric invariance), and (c) item intercepts (scalar invariance) was tested using an approximate measurement framework with Bayesian estimation. Results indicated that approximate metric and scalar invariance was established. From a methodological standpoint, this study demonstrated the usefulness and flexibility of Bayesian estimation for single-sample and multigroup analyses of measurement instruments. Substantively, the current findings suggest that the measurement of mental toughness requires cultural adjustments to better capture the contextually salient (emic) aspects of this concept. [ABSTRACT FROM AUTHOR]

The building sector accounts for over 40% of global energy consumption. The utilization of renewable energy systems such as the solar-assisted heat pump (SAHP) in buildings has been shown to improve building energy efficiency and achieve carbon neutrality. This paper presents a review of the research and development of solar-assisted heat pumps for buildings in China. It firstly introduces the different stages of solar-assisted heat pump research. Secondly, the research on different types of heat pumps, the core components of heat pumps, the computer software used, and the economic feasibility evaluation of solar-assisted heat pumps are presented. Thirdly, the application of SAHPs in practical projects is examined and relevant regulations, standards, and policies for solar-assisted heat pump development in China are highlighted. Finally, recommendations for the future development of solar-assisted heat pumps in China are suggested. [ABSTRACT FROM AUTHOR]

Objective To preliminarily explore the correlation of positive occipital sharp transients of sleep (POSTS) in MEG and EEG, and summarize the characteristics of MEG POSTS morphology and localization. Methods The MEG and EEG signals were simultaneously recorded in 5 healthy subjects during sleep, who were recruited from December 2020 to August 2021 in Beijing Tiantan Hospital, Capital Medical University. The features of MEG POSTS and its relationship with EEG POSTS were summarized. Single equivalent current dipole (ECD) model was used to conduct source imaging for POSTS. Results About 564 EEG POSTS during sleep were recorded in 5 subjects. There were 359 simultaneous MEG POSTS in occipital region after exclusion of the POSTS overlapping with heart beat in ECG. The appearance rate of MEG POSTS was 73.42% (359/489). The MEG POSTS showed great variability in morphology. MEG POSTS dipoles were located mainly in bilateral midline regions of occipital lobe, including calcarine sulcus, lingual gyrus and cuneus; some in other parts of occipital lobe away from midline regions, such as medial occipitotemporal gyrus, lateral occipitotemporal gyrus and lateral occipital cortices; and a small portion in bilateral parietooccipital sulcus and precuneus. Conclusions MEG POSTS has characteristics different from EEG POSTS, so it is important to recognize POSTS correctly in clinical MEG reading to discriminate between physiological and pathological waves and provide precise information for presurgical evaluation of epilepsy. [ABSTRACT FROM AUTHOR]

Ancient Chinese stone arch bridges are an important kind of architectural heritage in China, and they are often threatened by potential collapse problems. The stone arrangements of the arches in ancient Chinese stone arch bridges are quite different from those in Western countries, which may lead to different collapse modes. Thus, the collapse mechanisms of arches with typical "Chinese stone arrangements" urgently need to be studied. In this paper, the stone arrangements commonly used in ancient Chinese stone arch bridges were first investigated and summarized in detail. Then, finite element models of four typical arches with different stone arrangements were established to study their mortar failure processes, collapse modes, and bearing capacities. After that, the influence of the friction coefficients of the voussoirs on the collapse modes and the bearing capacities of these typical arches was analyzed. The results show that the stone arrangements used in ancient Chinese stone arch bridges can generally be divided into three groups according to their lateral linkages. The bearing capacities of the four typical arches are sorted as follows when the friction coefficient is 0.3: the FJBL method > the HLFJBL method > the HL method > the BL method. When the friction coefficient decreases from 0.3 to 0.1, the live-load bearing capacities of these arches decrease by 33%–55%. When the friction coefficient increases from 0.3 to ∞, the live-load bearing capacities of these arches increase by 3%–11%. The study results can provide a scientific basis for the conservation of ancient Chinese stone bridges. [ABSTRACT FROM AUTHOR]

BACKGROUND Broflanilide has been registered in China for the control of Lepidoptera and Coleoptera pests, and is widely used to control the target pests at lethal and sublethal levels. The lethal and sublethal effects of broflanilide on the common cutworm (CCW) Spodoptera litura Fabricius, a representative Lepidopteran pest in agricultural crops, were examined to explore its ecological influence on pests. RESULTS: In F0, broflanilide had little influence on the hatchability of eggs, but significantly reduced the neonate survival rate. The lethal activity of broflanilide towards third‐instar larvae and adults was 0.13 mg kg–1 (LD50) and 3.59 mg L–1 (LC50) respectively at 48 h. After being treated with a sublethal dose (LD10 and LD30) of broflanilide, the duration of third‐ to sixth‐instar larvae and the mean fecundity of reproductive females were significantly increased, but pupation rate, weight of pupae and life‐cycle rate were significantly decreased. In F1, the duration of F1 larvae and the doubling time were prolonged, whereas the rates of pupation and the life cycle were decreased by 14.92% and 18.00%, respectively. The intrinsic rate of increase, finite rate of increase and net reproductive rate in the sublethal group were lower than in the control group. The relative fitness of F1 treated by LD10 and LD30 was 0.81 and 0.66, respectively. CONSLUSION: Broflanilide not only has highly lethal activity, but also suppresses the population growth and progeny of CCW, as a critical factor for guidelines of its usage in the field. [ABSTRACT FROM AUTHOR]

Background: Diagnostic criteria for sarcopenia have not been established in Chinese. This study established criteria based on the L3‐skeletal muscle index (L3‐SMI) and assessed its value for outcomes predicting in cirrhotic Chinese patients. Methods: Totally 911 subjects who underwent a CT scan at two centres were enrolled in Cohort 1 (394 male and 417 female subjects, aged 20–80 years). The data of those subjects younger than 60 years (365 male and 296 female subjects) were used to determine the reference intervals of the L3‐SMI and its influencing factors. Cohort 2 consisted of 480 patients (286 male and 184 female patients) from three centres, and their data were used to investigate the prevalence of sarcopenia and evaluate the value of L3‐SMI for predicting the prognosis and complications of cirrhosis. Results: Age and sex had the greatest effects on the L3‐SMI (P < 0.001). The L3‐SMI scores were clearly higher in male patients than in female patients (52.94 ± 8.41 vs. 38.91 ± 5.65 cm2/m2, P < 0.001) and sharply declined in subjects aged ≥ 60 years. Based on the mean −1.28 × SD among adults aged < 60 years, the L3‐SMI cut‐off value for sarcopenia was 44.77 cm2/m2 in male patients and 32.50 cm2/m2 in female patients. Using these values, 22.5% of the cirrhotic patients (28.7% of male patients and 11.9% of female patients) were diagnosed with sarcopenia. Compared with non‐sarcopenia individuals, sarcopenia patients had lower body mass index (21.28 ± 3.01 vs. 24.09 ± 3.39 kg/m2, P < 0.001) and serum albumin levels (31.54 ± 5.93 vs. 32.93 ± 5.95 g/L, P = 0.032), longer prothrombin times (16.39 ± 3.05 vs. 15.71 ± 3.20 s, P = 0.049), higher total bilirubin concentrations (41.33 ± 57.38 vs. 32.52 ± 31.48 μmol/L, P = 0.039), worse liver function (Child–Pugh score, 8.05 ± 2.11 vs. 7.32 ± 2.05, P = 0.001), higher prevalence of cirrhosis‐related complications (81.82% vs. 62.24%, P < 0.001) and mortality (30.68% vs. 11.22%, P < 0.001). Overall survival was significantly lower in the sarcopenia group [risk ratio (RR) = 2.643, 95% confidence interval (CI) 1.646–4.244, P < 0.001], accompanied with an increased cumulative incidence of ascites (RR = 1.827, 95% CI 1.259–2.651, P = 0.002), spontaneous bacterial peritonitis (RR = 3.331, 95% CI 1.404–7.903, P = 0.006), hepatic encephalopathy (RR = 1.962, 95% CI 1.070–3.600, P = 0.029), and upper gastrointestinal varices (RR = 2.138, 95% CI 1.319–3.466, P = 0.002). Subgroup analysis showed sarcopenia shortened the survival of the patients with Model For End‐Stage Liver Disease score > 14 (RR = 4.310, 95% CI 2.091–8.882, P < 0.001) or Child–Pugh C (RR = 3.081, 95% CI 1.516–6.260, P = 0.002). Conclusions: Sarcopenia is a common comorbidity of cirrhosis and can be used to predict cirrhosis‐related complications and the prognosis. [ABSTRACT FROM AUTHOR]

Objective: To evaluate the efficacy of transjugular intrahepatic portosystemic shunt (TIPS) and non‐TIPS therapy (endoscopy and/or nonselective beta‐blockers [NSBB]) in patients with cirrhosis and active variceal hemorrhage who did not respond to high‐dose vasoactive drugs and required balloon tamponade for hemostasis. Methods: Medical records of cirrhotic patients who did not respond to high‐dose vasoactive drugs and required balloon tamponade for hemostasis at five university hospitals in China between January 2011 and December 2018 were reviewed. Treatment outcomes were compared between the TIPS and the non‐TIPS groups. Results: Treatment failure of variceal hemorrhage within 5 days was reported in six patients of the non‐TIPS group (N = 70) and none of the TIPS group (N = 66) (P =.028). The TIPS group had a higher 1‐year variceal rebleeding‐free rate compared with the non‐TIPS group (95.5% vs 60.0%, P <.001). One patient treated with TIPS and nine with non‐TIPS therapy experienced rebleeding within 5 days and 6 weeks after the intervention (P =.009). The cumulative 1‐year survival rate was higher in the TIPS group than in the non‐TIPS group (93.9% vs 78.6%, P =.01). The TIPS group had a higher incidence of hepatic encephalopathy within one year compared with the non‐TIPS group (18.2% vs 4.3%, P =.026). Conclusion: For patients with cirrhosis and active variceal bleeding who do not respond to high‐dose vasoactive agents and require a balloon tamponade for hemostasis, TIPS may be an appropriate treatment choice. [ABSTRACT FROM AUTHOR]

Square‐rebar reinforced concrete structures during the republic of China (ROC) (1912–1949) have special material properties and structural characteristics. To perform nonlinear finite element simulations of this special type of structure more accurately, a specialized bond‐slip constitutive model is built. Eighteen central pullout specimens were designed based on the ROC concrete mix proportions and the square‐rebar. Then, the test data were fitted with the universal global optimization method and the minimum Euclidean distance point method was chosen to calculate the inflection point matrix of the bond‐slip constitutive model. Finally, the main factors influencing the bond‐slip behavior of the ROC square‐rebar reinforced concrete were analyzed. The research results show that the corrosion of the square‐rebar produces a negative effect on the whole structure and a modified bond‐slip regression curve considering the size effect is obtained. The research results can provide a scientific basis for the nonlinear calculation of ROC square‐rebar reinforced concrete structures considering the bond‐slip behaviors. Highlights: The universal global optimization method of bond‐slip was used to fit the test data.The minimum Euclidean distance point method and the minimum Mahalanobis distance point method were used to centralize the fitting inflection points.A modified four‐line bond‐slip constitutive model considering the size effect was proposed for square‐rebar reinforced concrete during the republic of China (1912–1949).Bond‐slip behavior between concrete and rebar was modeled by finite element method. [ABSTRACT FROM AUTHOR]

Aim: Using a longitudinal design, the purpose of this study was to test a model integrating perceptions of the school neighbourhood environment with constructs from the Theory of Planned Behaviour (TPB) to predict transport-related cycling among Chinese college students. Methods: A sample of 630 (Mage = 18.95 years; SD = 1.16) Chinese college students completed baseline measures that included perceptions of the school neighbourhood environment, TPB constructs, transport-related cycling, and covariates. Of those, 547 students (Mage = 18.90 years; SD = 0.92) also completed measures of transport-related cycling one month later. Results: Findings showed that intention had a direct effect on students' transport-related cycling, while attitudes, subjective norm, and perceived behavioural control predicted cycling indirectly via intention. Perceptions of the school neighbourhood environment did not provide an indirect effect on cycling via the TPB constructs, although some perceived environmental factors had indirect effects on intention via attitudes and subjective norm. Further, those who perceived better street connectivity showed a larger intention-cycling relationship than those who perceived less street connectivity. Conclusions: Findings of this study highlight the importance of integrating perceptions of the school neighbourhood environment with the TPB constructs to explain transport-related cycling through both intention formation and action control (i.e. translating intention into behaviour). The identified moderator of perceived street connectivity on the intention-cycling relationship suggests that efficient cycling routes may impact action control of cycling. Future research applying dual process and action control models beyond TPB may contribute to the identification of the multilevel determinants of transport-related cycling. [ABSTRACT FROM AUTHOR]

Background: This study examined the effectiveness of a theoretical framework that integrates self-determination theory (SDT) and the theory of planned behavior (TPB) in explaining the use of facemasks to prevent seasonal influenza among Hong Kong older adults.Methods: Data were collected at two time points in the winter in Hong Kong, during which influenza is most prevalent. At Time 1, older adults (N = 141) completed self-report measures of SDT (perceived autonomy support from senior center staff, autonomous motivation for influenza prevention) and TPB (attitude, subjective norm, perceived behavioral control, and intention for influenza prevention) constructs with respect to facemask used to prevent infection. Two weeks later, at Time 2, participants' acceptance of a facemask to prevent influenza in the presence of an experimenter with flu-like symptoms was recorded.Results: Path analysis found that perceived autonomy support of senior center staff was positively and significantly linked to autonomous motivation for facemask use, which, in turn, was positively related to intentions to wear facemasks through the mediation of attitude, subjective norm, and perceived behavioral control. However, the effect of intention on facemask use was not significant.Conclusions: Results generally support the proposed framework and the findings of previous studies with respect to intention, but the non-significant intention-behavior relationship may warrant future research to examine the reasons for older adults not to wear facemasks to prevent seasonal influenza despite having positive intentions to do so. [ABSTRACT FROM AUTHOR]

There is an increasing research interest in the concept and measurement of mental toughness. This study examined the psychometric properties of the 8-item Mental Toughness Inventory (MTI) in two Chinese samples: 503 youth athletes and 513 university students. The unidimensional model of the MTI was confirmed and measurement invariance between males and females was supported in both samples. As expected, mental toughness was positively associated with the three basic psychological needs and effort in the athlete sample, and with life satisfaction in the student sample. Excellent internal consistency reliability was found in both samples, and good test–rest reliability was also demonstrated in the student sample. Collectively, these findings provide further psychometric evidence for the MTI and support the utility of the scale in China. [ABSTRACT FROM AUTHOR]

Ground cherry (Physalis pubescens) is widely cultivated in Northeast China as one of its popular fruits. In the summer of 2017, suspected bacterial disease symptoms consisting of water-soaked spots and brown interveinal necrotic lesions with chlorotic margins were observed on ground cherry leaves in a field of Hailun County in Northeast China. From infected leaves, bacteria with pale-yellow, mucoid, domed circular colonies were repeatedly isolated. Based on biochemical tests and genetic characterizations of hrpB and concatenated four housekeeping genes (lepA-gyrB-gapA-gltA), the bacteria isolates obtained in this study were identified as Xanthomonas euvesicatoria pv. euvesicatoria. Pathogenicity of these isolates was confirmed on ground cherry, tomato and pepper seedlings by artificial inoculation. It was further confirmed that none of the related pathogens X. vesicatoria, X. gardneri or X. euvesicatoria pv. perforans were detected by species-specific PCR in field samples. To our knowledge, this is the first report of X. euvesicatoria pv. euvesicatoria causing bacterial spot of ground cherry in China. [ABSTRACT FROM AUTHOR]

In this article, the authors discussed the development of a three-stage model of adversity coping in which Chinese athletes were categorized into three stages: climb, plateau, and enlightened stage. Specific, stage-related sport psychology services are recommended in this model. Particularly, sport psychology practitioners are encouraged to assist climb-stage athletes with mental skills and achievement motivation and help coaches establish an empowering motivational climate. Rational emotive behavioral therapy (REBT) and acceptance and mindfulness skills are recommended to help plateau-stage athletes overcome irrational and negative beliefs and habits. Finally, sport psychology services provided to enlightened-stage athletes should focus on developing an appreciation of the meaning and value of a sporting career, as well as enhancing work-life balance. [ABSTRACT FROM PUBLISHER]

BACKGROUND Osthol is a natural coumarin and lead compound that has been developed into commercial fungicides in China. Natural coumarins comprise five major subtypes: simple coumarins, linear furanocoumarins, angular furanocoumarins, linear pyranocoumarins and angular pyranocoumarins. Studies pertaining to the antifungal activities of linear pyranocoumarins are few, and no reports exist for the antifungal activities of angular pyranocoumarins. In order to discover more antifungal natural coumarins, we synthesised a series of simple natural coumarins and isolated several plant-based furanocoumarins and pyranocoumarins using previously described methods. The compounds were biologically evaluated against some plant fungal pathogens. RESULTS Several of the 35 coumarins evaluated here exhibited strong activities against specific fungal species, including compound 25 (Pd-D-V, a linear pyranocoumarin), compound 26 (libanorin, an angular furanocoumarin) and compound 34 (disenecioyl khellactone, an angular pyranocoumarin). Compound 25 exhibited a high activity against Sclerotinia sclerotiorum ( EC50 = 13.2 µg mL−1); compound 34 displayed a strong antifungal activity against Botrytis cinerea ( EC50 = 11.0 µg mL−1). CONCLUSION This study demonstrates that several natural coumarins (one linear pyranocoumarin and one angular pyranocoumarin in particular) exhibit strong antifungal activities. These results call for further studies, where these coumarins can be examined as potential lead compounds for developing novel antifungal agents. © 2016 Society of Chemical Industry [ABSTRACT FROM AUTHOR]

Previous research suggests that mindfulness and experiential avoidance are negatively and positively related to athlete burnout, respectively. It is unknown, however, whether experiential avoidance functions as a mediator between mindfulness and athlete burnout. To address this gap, 387 elite Chinese junior athletes (M= 15.44 years,SD= 1.42) completed self-report measures of mindfulness, experiential avoidance, and athlete burnout. Findings provided cross-sectional evidence that experiential avoidance mediated the inverse association from mindfulness to each of the three burnout dimensions. No gender difference of these indirect effects was revealed. This study is the first to test the theoretical sequence in which mindfulness is associated with athlete burnout via experiential avoidance and provide additional support the adaptive nature of mindfulness. [ABSTRACT FROM AUTHOR]

Objective Chinese allergic subjects have high levels of sensitization to house dust mite (HDM) and other indoor allergens. This study quantifies common indoor allergen levels in Chinese households. Methods Dust samples were collected from nine cities. Major allergens Der p 1 and Der f 1 from Dermatophagoides pteronyssinus and D. farinae , and specific antigens of Blomia tropicalis, Tyrophagus putrescentiae, Acarus siro , and cockroach species Blattella germanica and Periplaneta americana were measured by ELISA. Results HDM allergens were found in dust samples from bedding in 95% of the Chinese households. The median levels varied from <0.006 to 9.2 µg/g of dust, depending on the city. The percentages of households having HDM allergen levels associated with the risk of developing allergy sensitization and asthma were 65% and 25%, respectively. Specific antigens of the storage mite and cockroach were only found in samples from the southern and tropical regions of China. Levels of mite allergens were generally higher in samples from bedding compared to samples from the living room, even for storage mites, whereas levels of cockroach antigens were higher in the living room samples. Conclusion HDM allergens are present in bedding dust samples from most Chinese households. Cities in southern and central China have relatively high levels of HDM major allergens compared to cities in northern and western China. Antigens of storage mites and cockroaches are not as common as HDM allergens. [ABSTRACT FROM AUTHOR]

Many timber lounge bridges are found in the south of Zhejiang Province and the north of Fujian Province in China. The timber lounge bridge is a unique type of timber arch bridge structure worldwide. Most of these bridges have some damages due to the influence by environmental impact and human action. In order to scientifically preserve these timber lounge bridges, their architectural configuration, structural performance, and damage mechanisms should be studied first, and then some adaptive repair methods can be put forward. The Wenxing Lounge Bridge is a famous and typical example of this type of bridge. This study investigated in detail how to repair the Wenxing Lounge Bridge. Since this bridge had much serious damage, such as asymmetric deformation, inclination and torsion, cracking and deflection of some timber members, and the slipping-off of the scissors braces and the crossbeams, and since the bridge occasionally swayed when people walked across it, it needed to be repaired urgently. Through the detailed on-site surveying and visits to the local bridge craftsmen, the architectural configurations and the damage characteristics of this bridge were understood. The finite element model analysis of this bridge before damage and after damage was made respectively to study the structural performance. Finally, the reasons for the damages of this bridge were analyzed and the adaptive repair design of the bridge is presented here. This work serves as a model for similar timber arch bridges. [ABSTRACT FROM PUBLISHER]

Objectives. We investigated the action of triptolide in rats with adriamycin-induced nephropathy and evaluated the possible mechanisms underlying its protective effect against podocyte injury. Methods. In total, 30 healthy male Sprague-Dawley rats were randomized into three groups (normal group, model group, and triptolide group). On days 7, 28, 42, and 56, 24 h urine samples were collected. All rats were sacrificed on day 56, and their blood and renal tissues were collected for determination of biochemical and molecular biological parameters. Expression of miRNAs in the renal cortex was analyzed by a biochip assay and RT-PCR was used to confirm observed differences in miRNA levels. Results. Triptolide decreased proteinuria, improved renal function without apparent adverse effects on the liver, and alleviated renal pathological lesions. Triptolide also elevated the nephrin protein level. Furthermore, levels of miR-344b-3p and miR-30b-3p were elevated in rats with adriamycin-induced nephropathy, while triptolide treatment reversed the increase in the expression of these two miRNAs. Conclusions. These results suggest that triptolide may attenuate podocyte injury in rats with adriamycin-induced nephropathy by regulating expression of miRNA-344b-3p and miRNA-30b-3p. [ABSTRACT FROM AUTHOR]

Building on the work of Terry and colleagues (Terry, P. C., Lane, A. M., Lane, H. J., & Keohane, L. (1999). Development and validation of a mood measure for adolescents.Journal of Sports Sciences, 17, 861–872; Terry, P. C., Lane, A. M., & Fogarty, G. J. (2003). Construct validity of the Profile of Mood States-Adolescents for use with adults.Psychology of Sport & Exercise, 4, 125–139.), the present study examined the validity and internal consistency reliability of the Chinese version of the Brunel Mood Scale (BRUMS-C) among 2,548 participants, comprising adolescent athletes (n= 520), adult athletes (n= 434), adolescent students (n= 673), and adult students (n= 921). Both adolescent and adult athletes completed the BRUMS-C before, during, or after regular training and both adolescent and adult students completed the BRUMS-C in a classroom setting. Confirmatory factor analyses (CFAs) provided support for the factorial validity of a 23-item six-factor model, with one item removed from the hypothesised measurement model. Internal consistency reliabilities were satisfactory for all subscales across each of the four samples. Criterion validity was supported with strong relationships between the BRUMS-C, abbreviated POMS, and Chinese Affect Scale consistent with theoretical predictions. Multi-sample CFAs showed the BRUMS-C to be invariant at the configural, metric, strong, and structural levels for all samples. Furthermore, latent mean difference analyses showed that athletes reported significantly higher levels of fatigue than students while maintaining almost the same levels of vigour, and adolescent students reported significantly higher levels of depressed mood than the other three samples. [ABSTRACT FROM AUTHOR]

Highlights: [•] The careHPV is evaluated as a viable primary screening test in low-resource areas. [•] Compare careHPV to Hybrid Capture 2 with specimens stored in different media. [•] The careHPV has an excellent agreement with Hybrid Capture 2. [•] The careHPV may be recommended for screening cervical cancer in poor regions. [Copyright &y& Elsevier]

During the Han and Wei Dynasties, the scholastic class lives in a fierce conflict between officialdom and literary statuses, the anxiety hence giving rise to their literary ideas. Officialdom in fact belongs to the fundamental status of the scholastic class, undertaken by Confucian scholars and the officials out of scholars since the Western Han and forming rich and powerful families out of numerous officials and Confucians of generations in the Eastern Han. In such a social condition are they confronted with a discord choice: both to be officially oriented to helping with the empery cause on the one hand and to be scholastically amused with their belles-letters on the other. In consequence, their literary discourses embody such a dual characteristic. [ABSTRACT FROM AUTHOR]

Abstract: Based on molecular marker data from 112 microsatellites, the genetic structure of 97 maize inbred lines was analyzed using distance-based and model-based clustering methods. The dendrograms produced by both methods showed similar categories but the model-based dendrogram sorted the uncertain lines in the distance-based cluster tree, which provided reasonable explanation of the category. The analysis of genetic structure and model-based cluster showed that the 97 inbred lines were classified into 4 subpopulations, which were known as Reid, Lüda Red Cob (LRC), PB, and Sipingtou (SPT). Many inbred lines in a subpopulation contained certain genetic component from other subpopulations. According to Nei''s genetic distance, the Reid subpopulation was the closet to the LRC subpopulation and the farthest to the SPT subpopulation. For simplifying the heterotic groups, the subpopulations Reid and LRC could be integrated into one group, or even Reid, LRC, and PB could be integrated into one group. [Copyright &y& Elsevier]

Objectives The purpose of this study was to investigate the influence of sociocultural factors on Chinese Olympic sport psychology services. Design and methods Fifteen sport psychology consultants (SPCs), who served Chinese national teams for the 2008 Beijing Olympic Games, participated in this study after the Olympics. Semi-structured interviews were conducted within three months of the closing of the Olympics, followed by a hybrid approach to inductive and deductive thematic analyses. Results Two general dimensions of sociocultural influence on Chinese Olympic sport psychology services were identified: (a) the Whole-Nation System and (b) Chinese cultural characteristics. They consisted of eight higher order themes, which comprised 26 lower order themes. This study revealed that Chinese sport psychology services were enhanced by recognizing the features of the Whole-Nation System (e.g., resource centralization and top-down management) and the successful blending of these features with Chinese cultural characteristics (e.g., holistic thinking style, keeping face and interpersonal order) into the psychological service. Conclusions Sociocultural factors had a marked influence on Chinese Olympic sport psychology services, which enabled Chinese SPCs to provide a culturally competent service (e.g., prioritizing collective interests, respecting the authority of administrative officials and coaches, and keeping face with others) for the Beijing Olympic Games. [ABSTRACT FROM AUTHOR]

The fall armyworm (FAW) Spodoptera frugiperda (Lepidoptera: Noctuidae) is a severe agricultural pest, which has invaded into China in 2019 and caused heavy damage to maize. The γ-aminobutyric acid receptor (GABAR)-targeted insecticides including broflanilide, fluralaner and fipronil exhibit high toxicity towards lepidopteran pests. However, whether they could be used for control of FAW and their possible mode of action in FAW remain unclear. In this study, broflanilide, fluralaner and fipronil exhibited high oral toxicity in FAW larvae with median lethal dose (LD 50) values of 0.677, 0.711, and 23.577 mg kg−1 (active ingredient/ artificial food), respectively. In the electrophysiological assay, fluralaner and fipronil could strongly inhibit GABA-induced currents of homomeric FAW resistance to dieldrin 1 (RDL 1) receptor with median inhibitory concentration (IC 50) values of 5.018 nM (95% confidence interval (CI) 2.864–8.789) and 8.595 nM (95% CI 5.105–14.47), respectively, whereas broflanilide could not. In addition, the cytochrome P450 (P450), glutathione-S-transferase (GST) and carboxylesterase (CarE) activities were positively response to broflanilide, P450 and GST to fluralaner, and GST and CarE to fipronil, respectively, compared with those of control. In conclusion, we firstly reported a notable insecticidal activity of three representative GABAR-targeted insecticides to FAW in vivo , and in vitro using electrophysiological assay. The GST is the primary detoxification enzyme for three tested insecticides. Our results would guide the rotational use of GABAR-targeted insecticides in field. [Display omitted] • GABA receptor targeted insecticides are high toxicity to fall armyworm Spodoptera frugiperda. • Fipronil and fluralaner inhibit GABA-induced current of SfrRDL1 homomeric channel. • GST and CarE were positively response to broflanilide treated in vivo. [ABSTRACT FROM AUTHOR]

Zero-energy buildings have attracted interest worldwide as they consume less energy and can alleviate energy shortages caused by rapid economic development. This paper presents a review of the research and development regarding zero-energy buildings in China. First, it briefly introduces the evolution of the definition of zero-energy buildings and discusses the key influencing factors of such buildings in China. Then, envelope design, selection of mechanical and electrical equipment, and solar energy utilization aspects of zero-energy buildings are examined. Additionally, this paper discusses the development and application of zero-energy buildings in China, including project types, design methods, energy resources allocation, and energy operation management. Finally, this paper analyzes China's policies for zero-energy buildings, including incentive mechanisms, laws and regulations, and problems encountered, and provides suggestions for promoting zero-energy buildings in China. We expect this review to identify gaps and future directions for research and development, which will lead to new technologies, methods, policies, and standards that can be applied to zero-energy buildings. • Research and development of zero energy building in China is comprehensively reviewed. • Influencing factors and relevant zero-energy building design components are examined. • Development and application of zero-energy buildings in China are examined. • Zero energy policies in China are analyzed and suggestions for the promotion of zero-energy buildings are provided. [ABSTRACT FROM AUTHOR]

Introduction: Elite athletes' help-seeking on mental health might be influenced by their mental health literacy (MHL) and mental health experiences. The current study aimed to explore the MHL, experiences and help-seeking behaviours among elite athletes using a qualitative approach., Methods: Face-to-face semi-structured interviews were conducted among 20 Chinese elite athletes, 12 coaches, and 5 team officials. Interview data was analyzed using content analysis., Results: Seven main themes emerged from the analysis. The current study revealed that Chinese elite athletes suffered from various mental health issues and athletes' MHL levels, help-seeking attitudes and intentions, Chinese sports environments, and Chinese cultural background could impact their help-seeking behaviours., Conclusion: Support for Chinese elite athletes' mental health and help-seeking requires improvement., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision., (Copyright © 2024 Bu, Zhang, Liu, Han, Wang and Huang.)

This study aimed to examine the psychometric properties of the Multicomponent Mental Health Literacy Scale (MMHLS) among Chinese elite athletes. Particularly, the factorial validity, convergent validity, discriminant validity, concurrent validity, internal-consistency reliability, and test-retest reliability of the MMHLS were examined. A total of 320 participants were recruited from the Guangdong provincial sports training center in China. Data collection was conducted between 30 June and 31 July 2020 using electronic questionnaires. Confirmatory factor analysis (CFA), Rasch analysis, correlation analysis and independent-sample t -tests were conducted using Mplus 8.3 and ConQuest 2.0. The CFA results supported the factorial validity of the three-dimensional MMHLS, consisting of knowledge-oriented MHL, beliefs-oriented MHL, and resource-oriented MHL. Cronbach's alpha and composite reliability coefficients supported the internal-consistency reliability of the MMHLS. Moreover, the convergent and discriminant validities were supported for the subdimension of MHL-Knowledge, MHL-Beliefs, and MHL-Resources. Concurrent validity was demonstrated through correlations between MMHLS, help-seeking attitudes, and stigma. Rasch analysis provided further evidence of the psychometric quality of the instrument in terms of its dimensionality, item fit statistics, and rating scale effectiveness. Finally, test-retest reliability was 0.66 after one month. In conclusion, the 24-item three-dimensional MMHLS was verified to be a reliable and valid measurement of mental health literacy in Chinese elite athletes.

Background: There is on one hand sufficient evidence showing strong association between resilience and self-rated successful aging. On the other hand, strength training could contribute the cultivation of resilience among older adults. Therefore, the current study aims to examine the effectiveness of resistance training on resilience among Chinese older adults in Hong Kong., Methods: This study will apply a three-group, double blinded (outcome assessors and data analysts), randomized controlled trial (RCT) to examine the effectiveness of the interventions on resilience, functional fitness, and health related quality of life immediately after a 16-week intervention, as well as the residual effects 12 weeks after completion of the interventions., Discussion: It is expected that resistance training is promising or even superior to aerobic training in the improvement of resilience. Given the limited evidence on the literature, it is urgently needed to explore the effects of resistance training on the improvement of resilience in older adults. Findings of the current study can contribute to the development of effective resistant training programs for the promotion of resilience among older adults., Trial Registration: The trial is registered at the ClinicalTrials.gov PRS (Trial ID: NCT04690465 ; Date of First Posted: 30/12/2020).

Artemisiae Annuae Herba is a traditional Chinese medicine for clearing deficiency and heat. It is the only natural source of artemisinin, which is a specific antimalarial drug, and has been widely concerned all over the world. In addition to artemisinin, Artemisiae Annuae Herba also contains many sesquiterpenes, coumarins, flavonoids, volatile oils, polysaccharides and other chemical components, which show antipyretic, anti-inflammatory, antiviral microorganisms, anti-asthma, anti-oxidation, anti-tumor and other pharmacological activities. In addition to their own pharmacological activities, some components could enhance the antimalarial activity of artemisinin through different mechanisms at absorption and metabolism in vivo. In order to understand the pharmacokinetic characte-ristics of the chemical constituents contained in Artemisiae Annuae Herba and provide reference for the full development and clinical utilization of Artemisiae Annuae Herba resources in China, this present paper systematically collated the modern research literatures, and summarized the biosynthesis, in vivo analysis and pharmacokinetics of the chemical constituents in Artemisiae Annuae Herba.

Background: As an accessible and inexpensive activity in daily life for employees, transport-related walking is a promising focus of physical activity initiatives. The purpose of this study was to integrate worksite neighbourhood walkability with the theory of planned behaviour (TPB) to predict transport-related walking in Chinese employees using a longitudinal design., Methods: A sample of 157 employees (M age  = 33.26 years; SD = 7.18) reported their social cognition and worksite neighbourhood environment perceptions at the baseline. Self-reported transport-related walking was measured at two time points, 1 month apart., Results: Path analyses revealed that intention had a direct effect on walking, while attitudes, subjective norm, and perceived behavioural control had indirect effects on walking via intention. Past behaviour had a significant effect on walking, attenuating the intention-behaviour effect substantially. However, there was no indirect effect from perceived worksite neighbourhood walkability on walking through the TPB constructs. Furthermore, perceived neighbourhood walkability did not moderate the intention-walking relationship., Conclusions: Perceived worksite neighbourhood walkability had limited effects on transport-related walking, which seems to be a motivated and habitual behaviour. Habit-based interventions may be a priority over social cognitive and environmental change interventions, and future experimental studies are needed., (© 2019 The International Association of Applied Psychology.)

Di- n-butyl phthalate (DBP), as an endocrine-disrupting chemical that tends to be accumulated in crops, poses great risks to human health through the food chain. To identify the molecular mechanism underlying differences in their DBP accumulation, the root physiological and proteomic responses to DBP stress of two Brassica parachinensis cultivars, a high-DBP accumulator (Huaguan) and a low-DBP accumulator (Lvbao), were investigated. Root damage of greater severity and significantly greater ( p < 0.05) decreases in root protein content and root activity were detected in Lvbao than in Huaguan, suggesting that Lvbao had lower tolerance to DBP. In total, 52 DBP-responsive proteins were identified by two-dimensional electrophoresis and MALDI-TOF mass spectrometry. More proteins involved in basic metabolic processes, such as protein synthesis and energy metabolism, were downregulated in Lvbao, possibly explaining its lower tolerance and root damage. Several proteins involved in starch metabolism, cell-wall biosynthesis and modification, and stress response were activated in Huaguan, suggesting greater tolerance to DBP. Overall, differences in root proteome between the two cultivars might be responsible for the genotype-dependent DBP tolerance and accumulation in B. parachinensis.

There are over 60 species within the freshwater fish genus Sinocyclocheilus (Cypriniformes: Cyprinidae) distributed throughout the Yunnan-Guizhou Plateau and its surrounding areas in China. In recent years, the increasing number of new species described has raised some controversy about the validity of several species within this genus, notably the putative sympatric species pair S. qiubeiensis and S. jiuchengensis. To test the validity of S. qiubeiensis and S. jiuchengensis, we analyzed the complete sequences of the mitochondrial cytochrome b (CYTB) gene of 20 identified species and one outgroup species. Phylogenetic relationships were reconstructed using CYTB with maximum likelihood (ML) and Bayesian inference (BI) methods. Our phylogenetic results showed that all individuals of S. qiubeiensis and S. jiuchengensis clustered in one clade with strong support. In addition, the genetic distance between the two species was 0.11%, within the range observed at the intraspecific level. The most recent common ancestor of S. qiubeiensis and S. jiuchengensis dated back to 0.13 million years ago, indicating little time for complete speciation to have occurred. These results clearly support the viewpoint that S. jiuchengensis is a synonym of S. qiubeiensis.

Based on the current map data of park green space in the main urban area of Nanchang, the spatial database of park green space was set up with GIS technique, with the corresponding landscape indices being calculated by FRAGSTATS, the software of landscape pattern. Based on analyzing current landscape pattern of green space in Nanchang, the optimization strategy and scheme were proposed and the optimized landscape pattern was evaluated. The results indicated that the spatial distribution of patches in current park green space was uneven and area discrepancy was large, which is especially true in densely populated areas with less patch number of park green space and obviously low available area for disaster shelter. By substantially increasing the quantity and area of patches, improving the inter-patch connectivity, and increasing landscape fragmentation index appropriately, the "point-line-plane" pattern of park green space system in Nanchang would be optimized and the spatial distribution would be more rational, which could effectively enhance its role in biodiversity conservation, disaster prevention, and risk avoidance. The optimized indices of patch diversity, evenness and aggregation would be significantly increased, the dominance index would be reduced, and the landscape diversity would be more abundant.

Safer, more convenient methods for cervical sample collection and storage are necessary to facilitate human papillomavirus (HPV) DNA testing in low-resource settings. Our study aimed to evaluate the stability of cervical specimens collected with dry swabs and stored dry, compared to liquid-based cytology (LBC) samples, as detected by HPV DNA testing. Women with abnormal cytological findings or HPV-positive results at colposcopy were recruited from the West China Second University Hospital, Sichuan University, between October 2013 and March 2014. From each woman, physicians collected cervical specimens with a swab placed into a Sarstedt tube and a CytoBrush placed into LBC medium. Samples were randomly assigned to be stored at uncontrolled ambient temperature for 2, 7, 14, or 28 days and then were tested for 14 high-risk HPV (HR-HPV) types using the cobas HPV test. The rates of agreement between dry swab and LBC samples for any HR-HPV type, HPV16, HPV18, and the 12 pooled HR-HPV types were 93.8%, 97.8%, 99.4%, and 93.2%, respectively, with kappa values of 0.87 (95% confidence interval [CI], 0.83 to 0.91), 0.94 (95% CI, 0.91 to 0.97), 0.94 (95% CI, 0.87 to 1.00), and 0.86 (95% CI, 0.82 to 0.90). The performance of swab samples for detection of cervical precancerous lesions by means of cobas HPV testing was equal to that of LBC samples, even with stratification by storage time. Dry storage of swab-collected cervical samples can last for 1 month without loss of test performance by cobas HPV testing, compared to LBC samples, which may offer a simple inexpensive approach for cervical cancer screening in low-resource settings., (Copyright © 2017 American Society for Microbiology.)

The transgenic pollen spread is the main pathway of transgenic plant gene flow. The maximum distance of pollen dispersal (horizontal), the spatial dynamics of pollen movement (vertical), and the patterns of pollen dispersal are important considerations in biosafety assessments of genetically modified crops. To evaluate wheat (Triticum aestivum) pollen dispersal, we measured the pollen suspension velocity and analyzed pollen dispersal patterns under natural conditions in the Huanghuai River wheat-growing region in 2009. The pollen suspension velocity was 0.3-0.4 m/s. The highest pollen densities were detected in the north, northwest, and south of the pollen source. Pollen was dispersed over distances greater than 245 m in the northwest and northeast directions. At the pollen source center, pollen density decreased with increasing vertical height. In the north of the pollen source, the pollen density from 65 m to 225 m showed a wave-mode decrease with increasing height. The horizontal transport of pollen over longer distances fitted polynomial equations. In the north, the pollen density was highest at 45 m from the pollen source, and decreased with increasing distance. In the northwest, the pollen density showed a double-peak trend. In the northeast, pollen density was highest from 45 m to 125 m from the source. Wind speeds greater than the pollen suspension velocity and the duration of continuous gusts were the main factors affecting pollen dispersal. This information will be useful for determining the spatial isolation distances for hybrid seed production and for the commercial production of transgenic wheat.

Objective: To evaluate the role of human papillomavirus (HPV) genotyping in predicting the risk of cervical precancerous lesions or cancer in women with minor abnormal cytology., Methods and Materials: This study was conducted on 329 women with atypical squamous cells of undetermined significance (ASC-US) and 77 women with low-grade squamous intraepithelial lesions (LSIL) out of a total of 4,215 participants in a multicenter, cross-sectional study. Liquid-based cytology and the Hybrid Capture 2 test (HC2) were used to screen eligible women, and a Linear Array HPV genotyping test was performed on women with positive HC2 results., Results: The sensitivity and specificity for detecting cervical intraepithelial neoplasia grade 2 or worse (CIN2+) based on HPV 16/18 were 82% [95% confidence interval (CI): 52-95%] and 91% (95% CI: 87-94%) in women with ASC-US and 67% (95% CI: 35-88%) and 84% (95% CI: 73-91%) in women with LSIL. The women infected with HPV 16/18 had a significantly higher risk of developing CIN2+ than those infected with other high-risk HPV types in both the ASC-US (OR 9.93, 95% CI: 2.02-48.88) and LSIL (OR 7.45, 95% CI: 1.60-34.68) arms., Conclusions: Genotyping for HPV 16/18 greatly improves specificity, but at the expense of potential sensitivity in the triage of minor cytology abnormalities. The role of genotyping for HPV 16/18 in order to triage women with minor abnormal cytology should be further evaluated in future studies., (© 2015 S. Karger AG, Basel.)

Aim: To characterize high mobility group box chromosomal protein 1 (HMGB1) polymorphisms in patients infected with hepatitis B virus (HBV) and determine the different patterns in patient subgroups., Methods: A total of 1495 unrelated Han Chinese HBV carriers were recruited in this hospital-based case-control study. The HMGB1 1176 G/C polymorphism was genotyped by polymerase chain reaction-restriction fragment length polymorphism assay., Results: A significant association was observed between HMGB1 1176 G/C polymorphism and outcome of HBV infection. The subjects bearing 1176G/G genotype had an increased risk of susceptibility to chronic hepatitis B, liver cirrhosis and severe hepatitis B when compared with those bearing at least one 1176C allele., Conclusion: Patients with 1176G/G genotype of HMGB1 gene are more likely to have a progressive status in HBV infection.

Sugarcane mosaic virus (SCMV) is the most prevalent virus causing maize dwarf mosaic disease in northern China. A SCMV isolate, BD8, was obtained from the maize showing dwarf and mosaic symptoms in Baoding, China. The complete genomic sequence of BD8 is 9,576 nucleotides (nt) excluding the poly(A) tail. It contains one single open reading frame of 9,192 nt and encodes a large polyprotein of 3,063 amino acids (aa), flanked by a 5'-untranslated region (UTR) of 148 nt and a 3'-UTR of 236 nt. The entire genomic sequence of BD8 shares identities of 79.1-80.8% with those of other 13 SCMV isolates available in the GenBank at nt level, while their CP genes share identities of 76.9-82.6 and 82.8-86.9% at nt and aa levels, respectively. Phylogenetic analysis of the complete genomic sequences reveals that SCMV can be clustered to four groups: group I includes isolates from maize, group II consists of isolates from sugarcane or maize, groups III and IV contain single isolate of AU-A (AJ278405) and BD8, respectively. Thus, BD8 represents a new strain of SCMV. Furthermore analysis of the CP gene sequences of more isolates shows that BD8 is clustered to a group with the isolates from Thailand and Vietnam, which implies that isolates of this strain have been distributed in South Asia. In the greenhouse, BD8 can cause severe symptoms in all the 12 maize varieties tested with high incidence, indicating that BD8 is highly virulent.

Southern rice black-streaked dwarf virus (SRBSDV) is a novel Fijivirus prevalent in rice in southern and central China, and northern Vietnam. Its genome has 10 segments of double-stranded RNA named S1 to S10 according to their size. An isolate of SRBSDV, JNi4, was obtained from naturally infected maize plants from Ji'ning, Shandong province, in the 2008 maize season. Segments S7 to S10 of JNi4 share nucleotide identities of 72.6%-73.1%, 72.3%-73%, 73.9%-74.5% and 77.3%-79%, respectively, with corresponding segments of Rice black-streaked dwarf virus isolates, and identities of 99.7%, 99.1%-99.7%, 98.9%-99.5%, and 98.6%-99.2% with those of SRBSDV isolates HN and GD. JNi4 forms a separate branch with GD and HN in the phylogenetic trees constructed with genomic sequences of S7 to S10. These results confirm the proposed taxonomic status of SRBSDV as a distinct species of the genus Fijivirus and indicate that JNi4 is an isolate of SRBSDV. Shandong is so far the northernmost region where SRBSDV is found in China.

Objective: To access the relationship between atopy and bronchial asthma in adolescents., Methods: A cross-sectional study was conducted. Cluster randomized subgroups of schoolchildren who had participated in ISAAC phase III survey in Guangzhou were enrolled from april to May, 2002. Skin prick test with 5 groups totally for 9 common aeroallergens (dermatophagoides pteronyssinus, Dermatophagoides farinae, cat, Alternaria tenuis, mixed tree pollen, mixed grass pollen, American cockroach, German cockroach and mixed moulds) was performed. Asthma was defined as wheezing or whistling in the chest in the lifetime or in the last 12 months, or diagnosed asthma. Allergy disease was defined as any of asthma, rhinitis and eczema. A wheal size with the diameter of 3 mm or more after subtraction of the negative control was considered as positive and subjects with one or more positive reactions were considered as atopy. The degree of atopy and the sensitivity of the allergen were graded by atopic index (AI) and skin index (SI), respectively., Results: 1543 subjects were selected randomly for the skin prick test, and the response rate was 77.0% (1187/1543). 51.6% (613/1187) were males and 48.4% (574/1187) were females. The median age was 14 years old (range from 12 - 17 years old). The prevalence of asthma was 9.4% (111/1187), among whom 81.1% (90/111) also had rhinitis and 24.3% (27/111) had eczema. Asthma was more prevalent in 686 patients with rhinitis [13.1% (90/686)] or 200 patients with eczema [13.5% (27/200)] than those without rhinitis [4.2% (21/501), OR: 3.444, 95% CI: 2.110 - 5.622, P < 0.01] or eczema [8.5% (84/987), OR: 1.676, 95% CI: 1.055 - 2.663, P < 0.05]. The prevalence of atopy was 46.3% (549/1187) and the positive rates of house dust mite (Der p and Der f) were the highest [41.8% (496/1187) and 42.7% (507/1187), respectively]. Atopy was more common in asthmatic patients [71.2% (79/111)] than in those without any allergic diseases [26.4% (112/425), OR: 6.812, 95% CI: 4.276 - 10.853, P < 0.01]. Asthma was more prevalent in patients with atopy (14.4%) than those without atopy (5.5%, OR: 3.183, 95% CI: 2.075 - 4.883, P < 0.01). The relative risk of having asthma was increased with the higher AI degree. Univariate Logistic regression analysis showed that the risk factors for asthma were Der p (SI >/= 2), Der f (SI = 3 - 4), American cockroach, German cockroach, cat, Alternaria tenuis, mixed grass pollen. Multivariate Logistic regression analysis showed that Der p (SI = 3 - 4), and Alternaria tenuis were independent risk factors for asthma., Conclusion: Most asthmatic adolescents were allergic to house dust mite in the city of Guangzhou. The risk of asthma was positively correlated with the degree of atopy, as well as the sensitivity to Der p.