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Fourteen species of Cheiloneurus from China are studied. Cheiloneurus guangxiensis Zu, sp. nov., is described as new to science, and C. boldyrevi Trjapitzin & Agekyan, 1978, C. bouceki Anis & Hayat, 2002, C. gonatopodis Perkins, 1906, and C. hadrodorys Anis & Hayat, 2002 are newly recorded from China. A key to Chinese species based on females is also presented. [ABSTRACT FROM AUTHOR]

Self-management has been proposed as a crucial pathway to recovery from mental disorders. The aim of the current study was to explore self-management and its influential factors among individuals with anxiety disorders. Data were from a cross-sectional survey of 180 individuals diagnosed with anxiety disorders. Sociodemographic characteristics, anxiety, self-management, and social support were investigated and analyzed. Participants' mean self-management score was 79.04, with a score rate of 63%. Economic burden, number of relapses, and anxiety severity significantly influenced self-management among participants. Increased social support was correlated with greater self-management. Mental health nursing services should be directed toward individuals with anxiety disorders. [Journal of Psychosocial Nursing and Mental Health Services, 61(4), 27–35.] [ABSTRACT FROM AUTHOR]

The goal of financial management is to manage the purchase and sale of assets, the rational financing of funds, the management of cash flow in operations, and finally, the reasonable distribution of company profits in a certain task situation, which is simply the management of the "three statements" of the enterprise. The core issue of the financial mechanism is how to choose a centralized or decentralized management model, which requires the company to consider the internal and external environment, and according to the development of the company, the quality of employees and business characteristics of various factors, in order to make the best choice of the company's financial management model. Therefore, in the context of the epidemic, this article conducts research related to the financial management of listed companies based on convolutional neural network models (radial basis neural network, generalized regression neural network, wavelet neural network, and fuzzy neural network). This article, firstly, discusses the basic theories of macro- and micro-financial management of enterprises and financial management of listed enterprises, secondly, examines the overall financial management model of listed enterprises in China through methods such as the convolutional neural network model research method introduced in this article, and then, after an overall examination and analysis of the financial management situation of X-listed enterprises, finds the macro- and micro-status quo of financial management of listed enterprises in China under the epidemic, and in the sub. On the basis of the status quo, suggestions are made to build a financial management model that combines centralization and decentralization and to build a group financial risk management system. [ABSTRACT FROM AUTHOR]

The Porcine reproductive and respiratory syndrome virus (PRRSV), a single (+) RNA virus, is characterized by high genome variability and constant evolution. Owing to increasingly complex mutations, there is a growing difficulty in accessing the whole genome. Additionally, there is limited knowledge on PRRSV intra‐host nucleotide variants, which may reflect the complex viral‐host dynamics. Here, we performed next‐generation sequencing on four clinical lung tissues to reveal the genomic diversity and highlight virus‐host interactions. The complete genomes of the HN0713 and GDYJ1224 strains shared 90.7% and 91.3% homology with the lineage 1 strain NADC30, respectively, while the GDGZ0408 and GDHY0425 strains shared 92.0% and 91.6% homology with the JXA1 strain, respectively. Recombination analysis showed that the ORF5–7 genes of the GDGZ0408 and GDHY0425 strains, whose complete genomes belong to lineage 8.7 based on the phylogenetic tree, are both recombined with lineage 3 strains. Furthermore, nsp3, nsp10–12, ORF2 genes and a part of the 3′‐UTR of the GDHY0425 strain were provided by the lineage 5.1 strain. Two lineage 1 strains (GDYJ1224 and HN0713) were produced by a recombination of lineages 8.7 and 1. Additionally, the lineage 3 strain was associated with the recombinant HN0713 strain. We determined the intra‐host single nucleotide variant frequencies and found more than 200 sites at a frequency of >1% in all samples. GDGZ0408 with parts of the nsp9 and nsp10 genes of HP‐PRRSV lineage 8.7 presented more genetically diverse populations than others, indicating that lineage 8.7 might drive robust intra‐host single nucleotide variants (iSNVs). Moreover, in the iSNV pools, nsp2 and ORF2a presented the highest mutation dynamic. Overall, this study provided evidence for the alarmingly increasing recombination and ever‐changing evolutionary dynamics of PRRSV, and revealed the potential causes of vaccine escape, providing a novel insight into the nucleotide variant population in clinical samples. [ABSTRACT FROM AUTHOR]

In recent years, due to the increasing intensity of marine economic activities, such as port construction, land reclamation, and mariculture, bay ecosystems have been increasingly influenced by ecological and environmental threats. However, our current understanding of the ecosystem health level and its associated mechanisms are still insufficient in Haizhou Bay, China. Therefore, it is necessary to construct a comprehensive health framework to integrate and explain the dynamic changes in ecosystem health over a wider range. In this study, we established a comprehensive ecological health indicator system to calculate the ecosystem health index (EHI) for Haizhou Bay during 2012–2018 using the pressure–state–response (PSR) framework. Correlation analysis and barrier models were combined to explore the factors that affected sustainable development of the Haizhou Bay ecosystem. The EHI for Haizhou Bay was in a moderately healthy state during 2012–2018, with an overall increase of 25%, which indicated that the health quality of the ecosystem improved slightly. The pressure (+0.1073) and state (+0.1185) increased from moderately healthy to a relatively healthy state, and the response (+0.0866) was in a moderately healthy state. The three factors comprising industrial wastewater discharge, organic pollution index, and nutrition level index had the highest obstacle degrees during the study period, and the EHI had high correlations with land-based pollution (+0.79) and seawater quality (+0.75), which were the main factors that influenced the ecological health of Haizhou Bay. Our new evaluation framework developed for studying bay ecosystem health can be extended and applied to other bays with similar conditions. Our findings can also be used to provide recommendations for the conservation and management of the Haizhou Bay ecosystem, thereby contributing to its sustainable development. [ABSTRACT FROM AUTHOR]

This paper explores whether a Student's choice of major leads to certain personality traits and the reasons for this phenomenon. Specifically, we look at evidence from two Chinese universities, both of which specialize in agricultural studies. Using the Sixteen Personality Factor (16PF) questionnaire and the Neuroticism Extraversion Openness Five-Factor Inventory (NEO-FFI) questionnaire, we collected data from two groups of students: those who study agriculture-related majors (ARM), and those who study non-agriculture-related majors (NARM). The surveys all showed no significant change in personality traits during Students' freshman year. However, after 3 years of university study, significant personality trait changes were noted between seniors in the ARM and NARM groups. Whereas ARM seniors tended to be socially shy and lower in communicative competence, NARM seniors were better at expressing themselves and communicating with others. Although a Student's choice of profession has an influence on their personality traits, it is not the only factor. The differences between ARM and NARM training models and curricula are also undoubtedly significant. Moreover, the bias against ARM in Chinese society further magnifies the differences in personality traits among students with different majors. [ABSTRACT FROM AUTHOR]

The rise of e-shopping significantly changes the way that people shop. Transportation planners have a keen interest in the substitution of e-shopping for store shopping and its impact on transportation systems. The literature offers mixed findings on the relationship between online and store shopping. Few studies have explored this relationship in China where e-shopping has proliferated and retail land use and transportation systems have evolved. Using data gathered from adult Internet users in Nanjing, this paper applies structural equation modeling to investigate the relationships among store shopping, online shopping, and online searching. The results show that online shopping and store shopping have a positive association, however, the effect is from the latter to the former. Online searching positively influences both online shopping and store shopping. These results imply that e-shopping as an information channel promotes store shopping. [ABSTRACT FROM AUTHOR]

• Most built environment variables show threshold effects on e-bike ownership. • The non-linear effects of built environment elements vary by variable. • Distance to transit, employment density, and land use mix have positive effects. • Residential density has a negative influence. • Distance to city center shows an inverse V relationship with e-bike ownership. Although electric bikes (e-bikes) proliferate in China and other developing countries, few studies examine the association between the built environment and e-bike ownership. Moreover, the association is often assumed linear in variables. This study adopts a semi-parametric model to relax the linearity assumption and explores the complex relationships between built environment variables and e-bike ownership in Zhongshan, China. We found that almost all built environment characteristics have non-linear associations with e-bike ownership and the non-linear patterns vary by variable. Within certain thresholds, distance to transit, employment density, and land use mix are positively associated with e-bike ownership whereas residential density has a negative association. Furthermore, distance to city center shows an inverse V relationship with e-bike ownership. We recommended planners to deliberate land use and transportation policies to promote e-bike growth, but not facilitate reliance on cars. [ABSTRACT FROM AUTHOR]

The built environment impacts individuals’ participation in daily activities and associated travel (or activity-travel behavior). However, it is not well understood how these impacts differ between different socioeconomic groups (e.g. economically advantaged and disadvantaged people) and how neighborhood planning affects the difference. Using data of public housing and private housing residents in Hong Kong in 2010, this study applies the propensity score matching approach to identify differences in activity-travel behavior under different built environment settings for private and public housing residents respectively. We find that density, accessibility and self-containment collectively affect private housing residents’ auto ownership, travel time, trip frequency, and entertainment time spent at home, but have few influences on public housing dwellers. The different built environment effects are partly because the planning standards and guidelines in Hong Kong stipulate the provision of daily facilities and services such as grocery shops/supermarket, primary school and transit in proximity to public housing development. Thus, although economically disadvantaged people have limited transportation resources, neighborhood planning can adequately meet their daily needs even if they are placed in suburban areas. [ABSTRACT FROM AUTHOR]

Most studies regarding the effects of rail transit on auto ownership have yet to disentangle the influences of the built environment surrounding stations and residential self-selection from the impact of rail transit itself. There is also limited knowledge on the effects of rail investments in developing countries on ownership of mobility instruments, which has recently proliferated because of economic growth. Using the 2014 data from Xi’an, this study explores the joint influences of metro transit on the ownership of autos, bikes, ebikes, and motorcycles. The cross-sectional analysis shows that metro is negatively associated with auto ownership and ebike ownership whereas it has a positive association with bike ownership. The quasi-longitudinal analysis indicates that moving into metro neighborhoods is negatively associated with the changes of auto and ebike ownerships. These results suggest that metro development helps curb the growth of autos and fight against the negative consequences of ebikes, and has the potential to achieve sustainable travel. [ABSTRACT FROM AUTHOR]

Urbanization in developing countries greatly contributes to growing carbon emissions. Although studies have documented the urbanization effect, the science of consumption-based footprint assessments has yet to unpack various effects during the process of urbanization. Based on household expenditure data, this study innovatively proposes a methodology to conceptually and statistically deconstruct the observed urbanization effects on carbon footprint into selection effects and migration effects, which consist of human settlement effects and purposeful changes of migration (such as income and residential location). Applying propensity score matching and regression on the 2010 China Family Panel Study, we find that the apparent carbon-footprint difference between rural residents and migrants is about 1.5 t CO 2 e per capita. The migration effects account for about 2/3 of the apparent difference and the remaining 1/3 is due to selection effects. Urban settlement effects and the purposeful changes account for 73% and 27% of the migration effects, respectively. Transport sector is the key driver of carbon-footprint growth: it accounts for 60% of the migration effects. We conclude that travel behavior of rural migrants, currently in scarcity in the lite rature, merits further investigation, and policies should emphasize transit-oriented land use and transportation to achieve low-carbon urbanization. [ABSTRACT FROM AUTHOR]

Many cities have made massive investments on rail systems to substitute transit for driving. Some studies have considered the confounding effect of attitudes in the connections between rail transit and travel behavior. However, they often focused on the average effect of rail transit and assumed that individuals' responses to transit improvements do not vary by their tastes. Using the 2014 data from Xi'an in China, this study explores the interaction effect between metro transit (heavy rail) and the propensity (i.e., predicted probability) of living in neighborhoods with metro transit on transit use. The propensity is positively associated with commute by metro transit and bus. Further, individuals with a strong propensity use transit equivalently no matter whether they live near metro transit, but metro transit tends to promote transit commute for those with a weak propensity of living near metro transit. Overall, building a rail line helps enhance transit ridership. Planners should also consider the variation in responses by individuals with different tastes when using policies to shape urban travel. [ABSTRACT FROM AUTHOR]

The article discusses the rise in carbon emissions in China from the transportation sector. Topics discussed include environmental challenges associated with carbon emissions; relationship between travel modes and greenhouse gas emissions; and impacts of land use and transportation policies on travel patterns and associated carbon emissions.

• The presence of subway is positively associated with life satisfaction. • Walkability, transit quality, and accessibility are mediating variables. • Travel satisfaction is also a mediating variable. • The association is higher in China than in the U.S. Policymakers often claim that rail transit helps enhance residents' life satisfaction. However, efforts to examine its effects are limited, particularly in developing countries. Based on a case–control design in Xi'an, a developing city in China, this study employs the structural equation modeling approach to explore the association between subway and life satisfaction. The results show that subway is positively associated with life satisfaction through its links with quality of transit service, walkability, accessibility, and travel satisfaction. These mechanisms underlying the association between subway and life satisfaction suggest that station area planning and design need to be coordinated with subway deployment to maximize well-being benefits of subway. Furthermore, this study suggests that rail transit is a more impactful instrument for well-being enhancement in developing countries than in developed countries. [ABSTRACT FROM AUTHOR]

Both scholars and policy makers have noted the growing issue of poverty and deprivation during China's rapid urbanization. Often previous studies examine the spatial distribution of deprivation in inner cities and suburban areas, but fail to assess the whole region. Moreover, the cross-sectional nature of these studies is unable to discover its changes over time. This research aims to evaluate multiple deprivation in the administrative area of Guangzhou and its evolution from 2000 to 2010. Using the Fifth and Sixth Censuses, this study is based on 2643 neighborhood committees and 167 sub-districts (or towns) of inner city, suburban areas, and outer areas of Guangzhou. During the decade, there was persistent multiple deprivation in some areas of the inner city. The deprivation improved in suburban areas, but urban villages experienced deteriorating deprivation. Although urban-rural disparity became smaller in the outer areas, there were still some worst-hit neighborhoods. The evolution of multiple deprivation is collectively affected by institutional factors (including the dichotomous urban-rural system, economic restructure, and housing reform), and market factors (such as, market-selected urban regeneration, economic growth and individual residential mobility. This study helps governments to establish anti-poverty polices based on the characteristics of different areas and offers guidelines for urban regeneration planning in the inner city and rural planning of the outer areas. [ABSTRACT FROM AUTHOR]

• Household wealth plays a crucial role in car ownership decision in developing cities. • Banning motorcycles/E-bikes motivates people to become car owners. • It amplifies the adverse effects of income and built environment variables on car ownership. • The associations between built environment variables and car ownership are limited in size. • Nonlinear associations between built environment variables and car ownership are prevalent. Although many studies examine the relationship between the built environment and car ownership in large cities, few focus on smaller cities in developing countries. Their nonlinear and interaction relationships are often neglected. Using the 2019 data from Zhongshan, a medium-sized city in China, we employed gradient boosting decision trees to estimate the nonlinear and interaction effects of the built environment and motorcycles/E-bikes on car ownership. We found that wealth plays a crucial role in households' car ownership decisions. Most built environment variables have threshold associations with car ownership, but the size of the associations is limited. The findings suggest that polycentricity and densification around centers help mitigate the growth of cars. More importantly, motorcycles and E-bikes, particularly owning a second one, attenuate the positive effects of income and/or distance to city center on car ownership. This challenges the policies of banning motorcycles and E-bikes. [ABSTRACT FROM AUTHOR]

The sulfur-retention properties, mineralogical compositions, porosities and surface morphologies of two Chinese high-calcium coal ashes are studied by XRD, SEM and porometer analysis. It is found that the active calcium (CaCO3 and CaO) content in Shenmu coal ash prepared at 800 °C is 22.40% and its sulfation product (CaSO4) content is 17.79%, which are both higher than those in Huangling coal ash (respectively, 4.48% and 4.92%). With an increase in furnace temperature from 800 to 1200 °C, the porosity parameters of these two coal ashes dramatically decrease due to their intensely melting and no calcium compounds are found. [Copyright &y& Elsevier]

In advanced wastewater treatment plants on pig farms, meticulous design aims to eliminate intrinsic pollutants such as organic matter, heavy metals, and biological contaminants. In our field survey across Southern China, a notable disparity in wastewater treatment procedures among various farming facilities lies in the utilization of terminal chemical oxidation post-sedimentation tank. However, recent focus in wastewater surveillance has predominantly centered on antibiotic resistance genes, leaving the efficacy of virus removal in different effluent systems largely unexplored. To profile virus composition at the effluent, assess the virus elimination efficiency of chemical oxidation at the effluent end, and the potential environmental driver of virus abundance, we deployed a meta-transcriptomics approach to first determine the total virome in effluent specimens of terminal clean water tank system (CWT) and terminal chemical oxidation system (TCO) in Southern China pig farms, respectively. From these data, 172 viruses were identified, with a median reads per million (RPM) of 27,789 in CWT and 19,982 in TCO. Through the integration of analyses encompassing the co-occurrence patterns within viral communities, the ecology of viral diversity, and a comparative assessment of average variation degrees, we have empirically demonstrated that the procedure of TCO may perturb viral communities and diminish their abundance, particularly impacting RNA viral communities. However, despite the diminished abundance, pathogenic viruses such as PEDV and PRRSV persisted in the effluent following chemical deoxidation at a moderate RPM value, indicating a substantial in situ presence at effluent. Our environmental driver modeling, employing GLM and mantel tests, substantiated the intricate nature of virus community variation within the effluent, influenced heterogeneously by diverse factors. Notably, pond temperature emerged as the foremost determinant, while fishing farming exhibited a positive correlation with virus diversity (p < 0.05). This revelation of the cryptic persistence of virus communities in wastewater effluent expands our understanding of the varied responses of different virus categories to oxidation. Such insights transcend mere virus characterization, offering valuable implications for enhancing biosafety measures in farming practices and informing wastewater-based epidemiological surveillance., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Background: Benefit finding (BF) is correlated with mental health and recovery, and its presence will contribute to the recovery of patients with mental disorders. Most of the current tools for assessing BF in patients with somatic disorders are not adequate for patients with mental disorders. The present study proposes to introduce the Benefit Finding Questionnaire for People with Mental Disorders and to validate its psychometric properties., Methods: The Beaton translation model was used to translate and cross-culturally adjust the Japanese version of the Benefit Finding Questionnaire for People with Mental Disorders. A survey of 514 people with mental disorders was conducted from January 2022 to October 2022 using a general information questionnaire and a translated Chinese version of the Benefit Finding Questionnaire for People with Mental Disorders (BFQ-C) using a convenience sampling method. The quality of the questionnaire was examined in terms of item analysis, reliability, and validity., Results: The results of the item analysis showed that all items met the requirements. The interrater agreement of the BFQ-C was good, with an interrater agreement = 0.714; the values of the item-level content validity index ranged from 0.75 to 1.00; and the average of all item-level content validity index on the scale = 0.958. Exploratory factor analysis extracted three main factors "change in relationship with others," "change in spirituality," and "change in values and thinking styles"-and the cumulative variance contribution rate was 57.70%. The results of the confirmatory factor analysis were χ2/df of 2.194, Root Mean Square Error of Approximation of 0.075, and comparative fit index of 0.919, indicating that the model fitted well. The questionnaire had a Cronbach' alpha of 0.936, a split reliability of 0.956, and a retest reliability of 0.939., Conclusion: The BFQ-C demonstrated good reliability and validity, and can be used to assess the BF level of people with mental disorders (e.g., anxiety disorders, depressive disorders, schizophrenia, and bipolar disorders) in China., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2024 Cao et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)

Purpose: To explore the correlation between self-management and anxiety and quality of life in patients with anxiety disorders and to understand whether self-management can influence the relationship between anxiety and quality of life and provide a basis for improving their anxiety and quality of life., Methods: A cross-sectional survey of 245 patients with anxiety disorders in West China Hospital of Sichuan University was conducted using the Self-Management of Anxiety Disorders Scale, Self-rating anxiety scale (SAS), and World Health Organization Quality of Life-BBREF. The data were then analyzed using descriptive tests and Pearson correlation in SPSS 25. Bootstrap mediated effects tests were used to test the effect relationship between anxiety, quality of life and self-management scores in patients with anxiety disorders and Amos was used to establish the structural equation model., Results: The results of the correlation analysis showed that the total self-management score was positively correlated with the total quality of life score (r = 0.695, P <0.001), physical domain score (r = 0.552, P <0.001), psychological domain score (r = 0.661, P <0.001), social relations domain score (r = 0.542, P <0.001), and environmental domain score (r = 0.614, P <0.001). Additionally, it was negatively correlated with SAS score (r = -0.470, P <0.001). Self-management partially mediates the relationship between anxiety and quality of life, and the direct effect value of anxiety on quality of life was -0.44. The indirect effect value of self-management was -0.27, accounting for 38% of the total effect value., Conclusion: Self-management of patients with anxiety disorders was negatively correlated with anxiety and positively correlated with quality of life. It played a partially mediating effect between anxiety and quality of life. We recommend that healthcare providers pay attention to self-management interventions for patients with anxiety disorders to further improve their quality of life., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2023 Cao et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)

WHAT IS KNOWN ON THE SUBJECT?: Self-management comprises five core skills: "Problem Solving, Decision-Making, Resource Utilization, Forming a Patient/Healthcare Provider Partnership and Taking Action." Effective self-management among patients diagnosed with anxiety can reduce the number of relapses and improve treatment outcomes. Knowledge of the impact of the family atmosphere, well-being and illness symptoms on self-management in patients diagnosed with anxiety disorders is limited. WHAT DOES THE PAPER ADD TO THE EXISTING KNOWLEDGE?: This is the first study in China to explore whether family atmosphere and well-being of patients diagnosed with anxiety disorders affects self-management. This paper adds to the list of factors influencing self-management among patients diagnosed with anxiety disorders. SAS scores are a major factor influencing self-management among patients diagnosed with anxiety disorders. The subjective well-being of patients diagnosed with anxiety disorders can influence their self-management behaviour. Patients who experienced family harmony had significantly higher self-management scores than those who experienced family disharmony. WHAT ARE THE IMPLICATIONS FOR PRACTICE?: Nurses should encourage patients diagnosed with anxiety disorders to manage their condition while receiving treatment at home. Nurses should focus on patients diagnosed with anxiety disorders who have significant anxiety symptoms and low well-being. Nurses should emphasize the importance of the home environment in family self-management and affirm that a good home environment promotes patient self-management., Abstract: INTRODUCTION: Better self-management can improve treatment outcomes and reduce the number of relapses for patients diagnosed with anxiety disorders. However, the impact of well-being and the home environment on self-management among patients diagnosed with anxiety disorders is unclear in China., Aim: This study sought to determine the impact of the home environment, well-being and illness symptoms on self-management during home treatment for patients diagnosed with anxiety disorders., Method: This cross-sectional study was conducted with patients diagnosed with anxiety disorders. Data were collected with SAS, Self-Management Scale for People with Anxiety Disorders and Index of Well-being. Frequency, percentage, analysis of variance, Kruskal-Wallis and multiple linear regression analyses were used., Results: Home environment (p < .001), self-perceived quality of life (p = .015), well-being index (p = .002) and SAS total score (p = .033) had a major impact on self-management in patients diagnosed with anxiety disorders (n = 245)., Discussion: Family disharmony, poor self-perceived quality of life, high SAS scores and low levels of well-being were significant influences on self-management among people diagnosed with anxiety disorders., Implications for Practice: Nurses should focus on the self-management of patients diagnosed with significant anxiety symptoms and low well-being and value the importance of the home environment in facilitating self-management among patients diagnosed with anxiety disorders., (© 2022 John Wiley & Sons Ltd.)

The Getah virus (GETV), a mosquito-borne RNA virus, is widely distributed in Oceania and Asia. GETV is not the only pathogenic to horses, pigs, cattle, foxes and boars, but it can also cause fever in humans. Since its first reported case in Chinese mainland in 2017, the number of GETV-affected provinces has increased to seventeen till now. Therefore, we performed an epidemiologic investigation of GETV in the Xinjiang region, located in northwestern China, during the period of 2017-2020. ELISA was used to analyze 3299 serum samples collected from thoroughbred horse, local horse, sheep, goat, cattle, and pigs, with thoroughbred horse (74.8%), local horse (67.3%), goat (11.7%), sheep (10.0%), cattle (25.1%) and pigs (51.1%) being positive for anti-GETV antibodies. Interestingly, the neutralizing antibody titer in horses was much higher than in other species. Four samples from horses and pigs were positive for GETV according to RT-PCR. Furthermore, from the serum of a local horse, we isolated GETV which was designated as strain XJ-2019-07, and determined its complete genome sequence. From the phylogenetic relationships, it belongs to the Group III lineage. This is the first evidence of GETV associated to domestic animals in Xinjiang. Overall, GETV is prevalent in Xinjiang and probably has been for several years. Since no vaccine against GETV is available in China, detection and monitoring strategies should be improved in horses and pigs, especially imported and farmed, in order to prevent economic losses., Competing Interests: Conflict of interest The authors declare that they have no conflict of interest., (Copyright © 2022 The Authors. Publishing services by Elsevier B.V. All rights reserved.)

The aim of this study was to investigate the contribution of chromosomal anomalies and the frequency of particular types of aberrations in general couples preparing for pregnancy and make recommendations for pregnancy on the basis of the medical literature. A total of 6,198 general couples were included in the present study. The karyotypes were generated from the peripheral blood lymphocyte cultures and the cytogenetic analysis was performed using G-banding. In 12,396 cases, chromosomal anomalies were detected in 59 cases (0.48%, 59/12,396). Among of them, the frequency of translocation was 0.35% (n = 43). Sex chromosomal anomalies accounted for 0.07% (n = 9), including Klinefelter syndrome (KS) (n = 4), Turner syndrome (TS) (n = 4), and XYY syndrome (n = 1). The others, including inversions (n = 6) and deletion (n = 1), accounted for 0.06%. Our study indicates that clinically important chromosomal defects are present at a remarkable frequency in the general couples in eastern China, suggesting pre-pregnancy cytogenetic analysis should be routinely performed among general couples in this area so that informed decision can be made, which will help to improve the quality of the pregnancy.