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Research excellence is one of the key missions of universities and an important engine for socio-economic development. However, the outbreak of COVID-19 has affected academic research in many ways. This study examines the impact of the COVID-19 pandemic on the research performance of science and engineering faculty members in China's top research universities. It is found that the pandemic caused a decline in the numbers and quality of published articles, and the effects persisted over time. The negative effect of the pandemic on research excellence was more pronounced in the older faculty groups and departments of science. In addition, the pandemic has harmed international research collaborations among academics, which is likely to obstruct research excellence in the long run. In the end, this paper proposes several policy recommendations to reinvigorate universities' capacity for research innovation in the post-pandemic era.

Prior research has used several indicators to represent parenting, from dyadic interactions between mothers/fathers and children (e.g., parenting styles, parental involvement) to triadic mother-father-child interactions (e.g., coparenting). This study applies network analysis to explore the interrelations between maternal and paternal coparenting, parenting styles, and parental involvement in families with adolescents in early (10-12 years), middle (13-15 years), and late (16-18 years) stages. Network analysis was used to identify central nodes (i.e., central parenting components) and central mechanisms (i.e., relations between central parenting variables) underlying the parenting network, providing a comprehensive and nuanced understanding of parenting. This study included 4,852 adolescents aged from 10 to 18 (M[subscript age] = 13.80, SD = 2.38, 51.5% females) in two-parent families across different regions of China. The results indicated that both maternal and paternal coparenting integrity and warm parenting style served as important bridges to connect the whole network; their integrity and emotional involvement were closely linked to other parenting variables. Also, the intrapersonal and interpersonal effects between mothering and fathering as well as adolescent developmental differences were found. If it is assumed that the parenting network is causal, the results suggest that supportive parenting should be considered the prime target for enhancing parenting systems. Adolescent developmental stages appear to be a vital factor influencing parenting intercorrelations, and interventions should be designed based on children's age groups.

The paper's primary goal was to analyze and find interactive piano learning systems using the Suzuki method. The sample of respondents engaged in the investigation was made up of 200 students from the [Zhejiang Conservatory of Music]. The estimated Cohen's kappa coefficient determined the level playing field of control and experimental groups at the start of training, as the coefficient was equal to 0.08. The survey measured the control and experimental group members' awareness of the Suzuki method. 29% of students in the control group and 18% of students in the experimental group were somewhat aware of the Suzuki method and relevant theoretical background. The training program was based on: learning sheet music by listening with Modartt Pianote app; developing fine motor skills using Garritan; teamwork based on YOUSICIAN (for the experimental group) and Ding Talk (for the group of children); regular homework using Native Instruments GarageBand (for the experimental group) and WeChat (for children) mobile apps. After a year of study, 54% of students learned to comprehend melodies of varying complexity by ear with further playing on the piano. 58% of control group members learned to play sophisticated tunes using musical notation. During the second phase, which involved 5-7-year-old children, most of group 3 members acquired strong knowledge. Involvement of 5-7-year-olds was done to compare the effectiveness of the developed program for different age categories.

Background: Migrants are the key population for tuberculosis (TB) transmission in China. However, it remains unknown how many migrants have received TB education and through what means. Objectives: To identify the rate and methods of TB education among migrants in China by using nationally representative data. Method: This study used secondary data analysis. The data were derived from the China Migrants Dynamic Survey 2014-2017. A total sample of 745,926 migrants was included in the following analysis. Information on TB education was collected through a self-report questionnaire. We used hierarchical logistic regression models to explore the relationship between the independent variables and the receipt of TB education. Results: Only 30.4% (n = 226,458) received TB education. Among all age-groups, participants between 65 and 69 years old had the highest TB education rate (33.4%). Bulletin boards (86.5%-91%), media (73% to 86.7%), and books/magazines (59.2%-67.4%) were the most common ways for migrants to receive TB education. Conclusions: Our study showed the rates of TB education in each region of China and indicated the significant disparity among the seven regions. Traditional media, off-line medical consultation, community advocacy, and bulletin boards should be the primary methods of delivering TB education. TB education campaigns targeting migrants with a low socioeconomic status should be actively promoted.

This study explores language practices of the Blang people and their perceptions of the changes in language ecology through the lens of chronotopes, hoping to better understand patterns of language shift in the Blang community in China. It takes a qualitative approach and draws on semi-structured interviews and ethnographic observations conducted in the Blang Mountain Township, Yunnan province, China. The study reveals that the Blang community has been undergoing a gradual shift from Blang to Chinese, and the decline of Blang has been most noticeable amongst the younger generation. This study uses a narrative approach with a focus on chronotopization in narratives to explore language shift. It contributes to our understanding of the way participants position themselves vis-a-vis the decline of their native tongue in the changing language ecology. Their accounts reveal the dynamic dialogic interrelationship between structure (conceptualised as external pressures) and agency (conceptualised as individuals' freedom of action). The study contributes to the methodology of using chronotopes in sociolinguistic research.

There is a growing awareness of the importance of financial education and literacy in personal economic success, yet not many Generation Z are proficient in this area. The lack of understanding can lead to consequences such as not recognizing the need for greater retirement savings, making poor spending decisions, or when overpaying off high-interest debt. In addition, many of the studies on financial education and literacy among Generation Z remain untapped in the context of China. As a result, the researcher emphasizes the evidence by mining data from the Web of Science database and analyzing the data using bibliometrics and content analysis. Contemporary research on financial education and literacy in the web of science has discovered that it is trending strongly across fields like environmental science, healthcare, energy, and economics, according to bibliometric data. Further investigation has uncovered the important writers, journal sources, and universities in China that are creating such knowledge. Subsequently, the content analysis on the focused area has yielded results related to recent findings from key authors, and how their studies describe the socio-demographic and psychological behavior of Generation Zs. As an implication, China's academic research reveals that Generation Zs' subjective and objective financial education may be absorbed into their financial self-beliefs, which affects how they handle their finances. Thus, financial education is instrumental to help them set clear financial goals and plan for the future.

Purpose: Generation Z (Gen Z) will account for a growing proportion of the global workforce in the coming years. Therefore, it is vitally important to understand this generation's unique perspectives and preferences regarding work. This exploratory study aims to examine the prioritisation and desirability of Gen Z work values according to respondents' nationality. Design/methodology/approach: Data for this study were collected through a survey among 1,188 undergraduate students enrolled in one university each in China, Germany, the Netherlands and Thailand. ANOVA test and Tukey post hoc analysis were used to find out the difference between the groups based on nationality. Findings: Findings indicate that nationality serves as a key differentiator in work value preferences. The findings challenge the concept of a global Gen Z as only two of the measured values, learning and visible results, were found to have universal appeal across the nationality groups. In spite of increased levels of global interconnectedness and accompanying crossvergence of values, the results show significant statistical differences in work values based on the respondents' nationality. Research limitations/implications: Because of the scope and explorative design of the present study, it cannot be certain that the findings are exclusively from Gen Z characteristics or influenced by other, non-cultural, variables. Practical implications: This study suggests there is a need for study programmes at a tertiary level to embed experiential learning components and individual study pathways in their curricula to enable students to develop realistic expectations about the workplace and their place in it. In turn, these programmes will be able to develop a competitive advantage in higher education landscape. Originality/value: The insights gained can be leveraged by internationally oriented study programmes, such as International Business (IB), to better address Gen Z needs and expectations.

In the West, the music practice of turntablism continues to gain traction and awareness both inside and outside of the music classroom, as DJing becomes more prevalent in mainstream music culture. This qualitative study investigates the extent and type of turntablism pedagogy in China, a country with different cultural and political values where traditional Chinese music remains the centre of Chinese music education. Twelve DJs from cities across China took part in a series of in-depth interviews. They were asked to recall their experiences learning how to DJ in China, as well as their opinions of turntablism's inclusion in music education. Findings showed that participants preferred independent learning methods. In particular, participants significantly depended on Chinese social media applications to learn about turntablism and develop a national DJing culture. An absence of turntablism and popular music pedagogy in Chinese music education was the main reason for participants' self-discovery and learning of turntablism. Findings also revealed a cultural disconnect between the younger generation engrossed in DJing versus the older generation's fixation on traditional Chinese music to uphold nationalism and patriotism in society. This study examines an ongoing struggle regarding the extent to which popular music performance practices can be accommodated to work with the political aims of Chinese music education.

Symbolic representation refers to the use of physical or psychological processes to represent an object in a symbolic form. The present study investigated the development of children's symbolic representation using a new measure of children's block constructions. Ninety children (44 girls) in three age groups (3-4, 4-5, and 5-6 years) were randomly assigned to reproduce an example of ancient Chinese architecture using either two-dimensional pictures or a three-dimensional scale model. Children in the 3-4 age group produced significantly better constructions in the pictures condition. This picture-superiority effect disappeared in the 4-5 age group. In the 5-6 age group, there was better dimensionality in children's constructions when they used a scale model as the referent. The data identified the age of 4-5 as a critical period for the development of children's symbolic representation to transfer relational information from a scale model to their construction.

Research Findings: Preschool social-emotional education has become an increasingly important area of research and practice in mainland China. The social development domain has been recognized as an independent preschool curricular domain since 2001. Little is known, however, about the specific practices that preschool teachers in China are using to promote children's social-emotional competence. An investigator-developed and validated measure, the "Social-Emotional Teaching Practices Questionnaire-Chinese" (SETP-C), was used to gather data about social-emotional practices from a sample of 1,599 Chinese teachers in 120 preschools. Chinese preschool teachers reported they were implementing many social-emotional practices included on the SETP-C, but were less likely to use and less confident in implementing practices that address the needs of children with persistent challenging behaviors. Teacher's role in the classroom, having teaching certification, years of teaching experience, use of a social-emotional curriculum, child-to-teacher ratio, inclusion of children with disabilities, and age group of children had statistically significant and noteworthy associations with teachers' reported frequency of use and confidence in implementing social-emotional practices. Practice or Policy: Findings from this study support the multidimensionality of preschool social-emotional practices and suggest the need for further attention to teacher, classroom, and program-wide variables related to teachers' practice implementation in support of young children's social-emotional competence.

The study investigates the attitudes and practices of early career researchers (ECRs) in regard to citation-based metrics and altmetrics, providing the findings in the light of what might be expected of the millennial generation and in the context of what we already know about researchers in today's 'culture of counting' governed scholarly world. The data were gathered by means of an international survey, informed by a preceding, 3-year qualitative study of 120 ECRs from 7 countries, which obtained 1,600 responses. The main conclusions are: (1) citation indicators play a central and multi-purpose role in scholarly communications; (2) altmetrics are not so popular or widely used, but ECRs are waking up to some of their merits, most notably, discovering the extent to which their papers obtain traction and monitoring impact; (3) there is a strong likelihood that ECRs are going to have to grapple with both citation-based metrics and altmetrics, mainly in order to demonstrate research impact; and (4) the Chinese are the most metric using nation, largely because of governmental regulations.

Postmortem human brain donation is crucial to both anatomy education and research. The China Human Brain Banking Consortium was established recently to foster brain donation in China. The purpose of this study was to gain information about the public perception of and attitudes toward brain donation and to identify factors that may impact the willingness to participate in brain donation among the Chinese people. A specifically designed questionnaire was delivered to community residents in Changsha (the capital city of Hunan province) with a total of 1,249 completed forms returned and statistically analyzed. The majority of the participants considered that brain donation would help medical research and education, and 32.0% of respondents agreed that the brain donation would help change the traditional Chinese funeral belief in keeping the body intact after death. However, participants aged over 60 years old were less supportive of this concept. Among all participants, 63.7% stated that they were not knowledgeable about brain donation, while 26.4% explicitly expressed a willingness to participate in brain donation. Age, gender, monthly household income, and knowledge about brain donation significantly affected the willingness. Compared with other age groups, a higher proportion of participants aged over 60 years old preferred to be informed by a medical college. To promote brain donation in China, especially among the elderly, better communication of its medical benefits and a reinterpretation of the Confucius view of the human body should be provided. Efforts are also needed to provide appropriate forums and sources of brain donation information to targeted communities and society in general.

According to the executive framework of prospective memory (PM), age-related differences in PM performance are mediated by age-related differences in executive functioning (EF). The present study further explored this framework by examining which specific components of EF are associated with PM differences between and within three age groups. A group of children (7-9 years; N = 108), adolescents (12-14 years; N = 112), and adults (17-23 years; N = 106) performed focal- and non-focal event-based PM (EBPM) tasks, a time-based PM (TBPM) task, and tasks measuring EF components. Differences between age groups in focal EBPM, non-focal EBPM, and TBPM performance were mediated by, respectively, differences in interference control and response inhibition, performance on the ongoing task, and differences in working memory and response inhibition. However, within-age group analyses only revealed WM updating as significant predictor of TBPM performance in the adolescent group. These results support and further qualify the executive framework of PM. The differences in outcome dependent on the examined age range might be important for explaining mixed results of previous studies regarding the precise EF components underlying age-related PM task performance differences.

This study examined whether there is a developmental difference in the emergence of an item-position effect in intelligence testing. The item-position effect describes the dependency of the item's characteristics on the positions of the items and is explained by learning. Data on fluid intelligence measured by Raven's Standard Progressive Matrices (SPM) and data on working memory tasks were collected from both primary school age children (7-8 years old) and secondary school age adolescents (12-13 years old). The item-position effect of SPM was represented and separated from the ability component by the fixed-links model. The results indicated a clear age difference: whereas the item-position effect was observed in the adolescents, it was not found in the primary school children. In addition, separating the item-position effect detected in the adolescents from the ability component led to a larger correlation with working memory than otherwise. These results suggest that age differences in intelligence test performance may not only reflect differences in the general ability but also in the sources of the item-position effect.

Throughout the world, gender defines an omnipresent and personal identity. Historically gender effects have ventured far beyond the biological aspects of reproduction and deep into societal constraints of action, appearance, freedom, and destiny. Gender provides convenient labels, descriptions, and expectations. Unfortunately history provides many examples where gender has been used as a tool of oppression. The history of the world's most populous nation, China, provides a long and interesting tale of gendered outcomes. We argue that across three generations China has progressed from the gendered atrocity of female footbinding to a somewhat genderless college admissions process. The current generation of China's young women is not only able to run on unfettered feet but also have unprecedented personal options, opportunities, and responsibilities denied to previous generations. This study addresses generational change specifically through the eyes and perspectives of the contemporary women of China. Our study focuses on three generations of women; each formed by very unique cultural and political situations within their natal country. China's contemporary young adult women, born between 1979 and 1985, are typically "only daughters" of a generation of one-child families resulting from China's one-child family policy. This unique generation has grown up without the competition of other siblings. Their mothers grew up in much different era, shortly after the People's Republic of China (1949) was established. These women's lives were affected by the Great Proletarian Cultural Revolution (1966-1976). On average, these women were born to large families with clear preferences for sons. Finally, we extend back another generation to the grandmothers of our seed sample who typically were in the first generation of Chinese women to be free from footbinding. The manuscript begins with a description and history of three historical milestones; each relevant to one of the contemporary generations included in this study. We then provide data showing the speed and direction of gendered outcomes. Finally, we provide a qualitative oral history study of these three generations of women in China through interviews with the young adult women, their mothers, and their grandmothers. The use of oral histories as primary sources has been promoted through several respected historical works (S. Wang 2006). (Contains 5 footnotes, 4 figures and 1 table.)

Although children often believe an adult's claims, they may have opportunities to check these claims by gathering relevant empirical evidence themselves. Here, we examine whether children seize such opportunities, especially when the claim is counterintuitive. Chinese preschool and elementary schoolchildren were presented with five different-sized Russian dolls and asked to indicate the heaviest doll. Almost all children selected the biggest doll. Half of the children then heard a false, counterintuitive claim (i.e., smallest = heaviest). The remaining children heard a claim confirming their initial intuition (i.e., biggest = heaviest). Children in both age groups typically endorsed the experimenter's claim even when it was counterintuitive. However, during the experimenter's subsequent absence, elementary schoolchildren explored the dolls more if they had received counterintuitive rather than confirming testimony whereas preschool children rarely explored, no matter what testimony they had received. Thus, with increasing age, children seize opportunities to test counterintuitive claims. [Supplemental materials are located at: http://dx.doi.org/10.1037/dev0000455.supp.]

This study is an investigation into Chinese EFL teachers' knowledge and understanding of teaching English as a foreign language within the context of a time of tremendous social change in China. In a medium-sized city, biographical narrative interviews and observation were used to three Chinese secondary EFL teachers, of three successive generations. An in-depth narrative analysis interpreting their metaphors, and constructing their life stories is employed to understand the biographical narrative data. It indicates how individual teacher's knowledge is both constrained and enabled by themselves and by the wider society they live in, and how change and continuity are intertwined in the teaching and learning practices of the three generations. This paper also addresses certain key issues in biographical narrative studies, namely subjectivity, representation, and cultural bearings, and teachers' knowledge, all of which constitute a form of pedagogy in educational research.

This study empirically investigated learning approaches of management graduate students in China. The representative sample consisted of 208 MBA students in a professional accreditation business program in careers, namely the part-time MBA program, provided by Zhejiang University (ZJU) during the 2010/2011 academic year. The instrument used to collect the study data was the Revised Two-factor Study Process Questionnaire (R-SPQ-2F), developed by Biggs et al. (2001). The data was fed into SPSS 16.0 version for analyses using t- test, correlations and ANOVA. There were no significant differences in the scores of the R-SPQ-2F questionnaire between the studied groups (gender and age groups) in the part time MBA program, ZJU. The deep approach to learning was found dominant among the participants regardless their age and gender differences. The results had an outstanding importance, with regard to some earlier studies stereotyping Chinese students as a "rote learners" using knowledge assimilation for the mastery of principles instead of critical analysis. (Contains 3 tables.)

A young person born in the 1980s said jokingly to a reporter, "No, you are a post-90s. I am a post-80s, not a post-90s, nor a post-85s." In his view, he was not of the same generation as the post-90s, who are a few years younger than him. They were egotists, selfish, obstinate, and hedonistic, lacked any sense of responsibility, and frequently mouthed strange expressions that ordinary people did not understand. In a word, they were a "failed generation" ("kuadiao de yidai"). Like the baton in a relay race, the title "failed generation" is being passed from the post-80s to the post-90s. The year 2008 is when the first batch of post-90s reached maturity and when some of them got into college. This article addresses the differing perspectives of the post-80, post-85, and post-90 youth, revealing how quickly developmental trends, technology and China's emergence globally have affected generational characteristics.

Young people represent the future, and youth is an eternal topic. In the 1970s when the American anthropologist Margaret Mead published her famous work "Generation Gap," research on generations gained sudden popularity worldwide, and ever since the 1980s when "Generation Gap" was brought to China, research by scholars in this country on the subject of generations has been on the rise. This article seeks to define the term "generation" and then trace the evolution of the concept as it became transformed into the current "Post-XX."

This study explores two aspects of the privatization of childhood in contemporary urban China: the emergent discourse on children's privacy and children's growing seclusion within the home. Drawing on ethnographic fieldwork, the author describes urban caregivers' engagement with the issue of children's privacy, and argues that we are now witnessing a transformation in Chinese notions of childhood, privacy and subjectivity. The result of a complex interaction between official discourses, demographic changes and economic forces, this transformation is also a product of the persistent influence of Confucian values, and the unique childhood experiences of a particular generation of urban Chinese parents. (Contains 15 notes.)

Many countries are considering lifelong learning, which is becoming an important education goal, and promoting lifelong learning in the information age. With the development of Information and Communications Technology (ICT), digital divides have become a major concern in the world. In this study, we focus on three dimensions of digital divides in the field of lifelong learning: education organization, age, and national penetration. Next, we report our findings that provide solutions for combating digital divides by developing web-based learning and support environments over a three-year period: (1) a blended learning support system that helps teachers manage learning resources and create blended learning programs and learners choose and participate in learning activities; (2) an "E-namoSupport" system for senior beginners to use the Internet, as implemented in Japan; (3) a "Senior Internet Support & Learning Environment" to help senior citizens improve their Internet literacy and enjoy the information age in China.

Background: Rifampicin-resistant pulmonary tuberculosis (RR-PTB) presents a significant threat to global public health security. China bears a substantial burden of RR-PTB cases globally, with Guizhou Province experiencing particularly alarming trends, marked by a continual increase in patient numbers. Understanding the population characteristics and treatment modalities for RR-PTB is crucial for mitigating morbidity and mortality associated with this disease. Methods: We gathered epidemiological, diagnostic, and treatment data of all RR-PTB cases recorded in Guizhou Province from January 1, 2017 to December 31, 2023. Utilizing composition ratios as the analytical metric, we employed Chi-square tests to examine the spatiotemporal distribution patterns of RR-PTB patients and the evolving trends among different patient classifications over the study period. Results: In our study, 3396 cases of RR-PTB were analyzed, with an average age of 45 years. The number of RR-PTB patients rose significantly from 176 in 2017 to 960 in 2023, peaking notably among individuals aged 23–28 and 44–54, with a rising proportion in the 51–80 age group (P < 0.001). Since 2021, there has been a notable increase in the proportion of female patients. While individuals of Han ethnic group comprised the largest group, their proportion decreased over time (P < 0.001). Conversely, the Miao ethnicity showed an increasing trend (P < 0.05). The majority of patients were farmers, with their proportion showing an upward trajectory (P < 0.001), while students represented 4.33% of the cases. Geographically, most patients were registered in Guiyang and Zunyi, with a declining trend (P < 0.001), yet household addresses primarily clustered in Bijie, Tongren, and Zunyi. The proportion of floating population patients gradually decreased, alongside an increase in newly treated patients and those without prior anti-tuberculosis therapy. Additionally, there was a notable rise in molecular biological diagnostic drug sensitivity (real-time PCR and melting curve analysis) (P < 0.001). However, the cure rate declined, coupled with an increasing proportion of RR-PTB patients lost to follow-up and untreated (P < 0.05). Conclusions: Enhanced surveillance is crucial for detecting tuberculosis patients aged 23–28 and 44–54 years. The distribution of cases varies among nationalities and occupations, potentially influenced by cultural and environmental factors. Regional patterns in RR-PTB incidence suggest tailored prevention and control strategies are necessary. Despite molecular tests advances, challenges persist with low cure rates and high loss to follow-up. Strengthening long-term management, resource allocation, and social support systems for RR-PTB patients is essential. [ABSTRACT FROM AUTHOR]

Background: The rapid population aging in China has been a big challenge to achieve the goal of ending the global tuberculosis (TB) epidemic. This study aimed to describe the temporal trend of TB burden in China during 1990 ∼ 2019 and to evaluate the effect of age, period, and birth cohort on domestic TB burden, with a specific focus on the elderly. Methods: The trends of incidence, mortality, and disability-adjusted life years (DALYs) of TB among human immunodeficiency virus (HIV) negative people were described using the data from the Global Burden of Disease 2019 study. Join-point regression model was applied to calculate the average annual percentage change (AAPC) of TB burden for different age groups. Age-period-cohort (APC) model was fitted for incidence and mortality, and relative risks (RR) were computed for each age group. Results: In 2019, the highest TB deaths (5.23 thousand, 95% uncertainty interval [UI]: 4.38 ∼ 6.17) and DALYs (155.18 thousand, 95%UI: 126.47 ∼ 190.55) were observed in the HIV-negative population aged 70 ∼ 74 years in China. The proportion of those aged ≥ 60 years in newly diagnosed TB patients without HIV coinfection increased from 23.82% in 1990 to 37.54% in 2019, while TB deaths rose from 48.70 to 68.64%. During the past 30 years, the AAPC of age-standardized mortality (-7.77, confidence interval [CI]: -8.44∼ -7.10) and DALYs (-7.48, 95% CI: -7.98∼ -6.97) among HIV-negative individuals have shown a decrease, while much slower in the age groups above 70-year-old. The period effect and cohort effect contributed to the decline of TB incidence and mortality, but the age effect led to increasing TB mortality, especially among the ages of 85 ∼ 89 years (RR = 4.59, 95% CI: 4.25 ∼ 4.95). Conclusions: The burden of TB remains considerable in the elderly population in China. More actions should be taken to improve case finding and the quality of TB healthcare for this high-risk population. [ABSTRACT FROM AUTHOR]

Limited information is currently available on the prevalence of and risk factors for tuberculosis infection (TBI) among close contacts of patients with pulmonary TB (PTB) in China. In this study, we estimated the burden of TBI among close contacts using QuantiFERON-TB Gold In-Tube assay (QFT) and identified factors associated with TB transmission among this high-risk population. From January 1, 2018 to August 31, 2020, we identified laboratory-confirmed patients with PTB from a population-based, multicentered, cluster-randomized control trial for tuberculosis preventive treatment. Close contacts of these patients were identified, interviewed, and tested using the QFT assay. We estimated TBI prevalence and calculated ORs and 95% CIs for TBI risk factors. A total of 3138 index cases and 8117 close contacts were identified. Of these contacts, 36 had PTB (a prevalence of 443.51 cases/100 000 population). Among the remaining 7986 close contacts; 3124 (39.12%) reported a positive QFT result. QFT positivity was significantly associated with older age (adjusted OR, 1.77; [95% CI, 1.27–2.47], 2.20; [95% CI, 1.59–3.05], and 2.74; [95% CI, 1.96–3.82]) for age groups: 35–44, 45–54, and 55–64, respectively) when compared with a younger age group: 5–14; longer contact duration (adjusted OR, 1.44; 95% CI, 1.22–1.69); and sharing of a bedroom (adjusted OR, 1.39; 95% CI, 1.18–1.65). Our findings indicate a high TBI burden among the close contacts of PTB. The results also highlighted that contact tracing and investigation for TBI are necessary and beneficial, particularly for those who are older, have had a longer contact duration, and share a bedroom. [ABSTRACT FROM AUTHOR]

Introduction: By constructing the sexual liberalism index (SLI), this study tests the hypothesis that social class impacts sexual liberalism in China. Methods: This study uses the Seventh World Value Survey (2017–2022) as data source. Based on survey questions regarding homosexuality, premarital sex, and casual sex, the author constructed a sexual liberalism index (SLI) and checked its correlation with social class by conducting a multivariate ordinary least squares (OLS) regression analysis. Control variables include gender, marital status, place of residence (urban or rural), and age group. Results: The results show that social class is a significant predictor of sexual liberalism, with higher social class corresponding to higher levels of sexual liberalism. Other predictors such as marital status, place of residence, and age group also have significant but smaller impacts on sexual liberalism. Conclusions: The overall level of sexual liberalism among the general population is limited. China's SLI value is low in both global and regional context. The study suggests that the "sexual revolution" in China is still ongoing. A variety of phenomena can be linked to conservative attitudes. Policy Implications: Policymakers could consider targeted support programs and educational campaigns for various groups based on their socioeconomic status. By prioritizing comprehensive sex education, promoting safe sex practices, and challenging societal norms, policymakers can contribute to fostering a more informed, inclusive, and supportive environment for diverse sexual attitudes and behaviors in contemporary Chinese society. [ABSTRACT FROM AUTHOR]

The long‐term incidence trends of 32 cancers in China remained unclear. Cancer statistics for young population were often presented in aggregate, masking important heterogeneity. We aimed to assess the incidence trends of 32 cancers in China from 1983 to 2032, stratified by sex and age groups. Data on cancer incidence from 1983 to 2017 were extracted from Cancer Incidence in Five Continents Volumes VI–XII. The age‐period‐cohort model was utilized to assess age and birth cohort effects on the temporal trends of 32 cancers in China, while the Bayesian age‐period‐cohort model was utilized to project future trends from 2018 to 2032. An increase in cohort effects is observed in some cancers such as thyroid and kidney cancers. Eight of the 12 obesity‐related cancers may rise in the 0–14 age group, and nine in the 15–39 age group from 2013 to 2032. Liver and stomach cancers show an increasing trend among the younger population, contrasting with the observed declining trend in the middle‐aged population. There has been a significant rise in the proportions of cervical cancer among females aged 40–64 (4.3%–19.1%), and prostate cancer among males aged 65+ (1.1%–11.8%) from 1983 to 2032. Cancer spectrum in China is shifting toward that in developed countries. Incidence rates of most cancers across different age groups may increase in recent cohorts. It is essential to insist effective preventive interventions, and promote healthier lifestyles, such as reducing obesity, especially among younger population. [ABSTRACT FROM AUTHOR]

Background: Tai Ji Quan (TJQ) has broad appeal to people of all ages and backgrounds. This study aimed to examine a variety of individual and environmental factors in the dissemination of TJQ to diverse practicing communities in China. Methods: A mixed-methods approach was utilized in the research design. Quantitative data were collected via an online survey using a national sample (N = 737), whereas qualitative data came from focus groups and in-depth interviews. Analysis was performed along the RE-AIM dimensions of reach, efficacy, adoption, implementation, and maintenance. Results: We divided TJQ experience into 4 distinct categories (nonlearners, current learners, quitters, and retainers) and observed significant patterns of variation along lines of occupation groups and age cohorts. A significant male/female difference was detected in TJQ experience among college students but not the general public, and having practicing family members was an important predictor of personal TJQ history. Varied TJQ experience has a significant impact on perceptions of TJQ's miscellaneous values as well as level of satisfaction with its health outcomes. Conclusions: Both individual (personal) and environmental (settings) factors are important in shaping personal decisions in TJQ engagement. An ecological approach coordinating individual factors and settings resources is essential in promoting TJQ to the general population. [ABSTRACT FROM AUTHOR]

Background: Cervical and breast cancers are among the top 4 leading causes of cancer-related mortality in women. This study aimed to examine age-specific temporal trends in mortality for cervical and breast cancers in urban and rural areas of China from 2009 to 2021. Methods: Age-specific mortality data for cervical and breast cancers among Chinese women aged 20–84 years were obtained from China's National Disease Surveillance Points system spanning the years 2009 to 2021. Negative binomial regression models were utilized to assess urban–rural differences in mortality rate ratios, while Joinpoint models with estimated average annual percent changes (AAPC) and slopes were employed to compare temporal trends and the acceleration of mortality rates within different age groups. Results: From 2009 to 2021, there was a relative increase in age-specific mortality associated with the two cancers observed in rural areas compared with urban areas. A rising trend in the screening age of 35–64 [AAPC: 4.0%, 95% confidence interval (CI) 0.5–7.6%, P = 0.026] for cervical cancer was noted in rural areas, while a stable trend (AAPC: − 0.7%, 95% CI − 5.8 to 4.6%, P = 0.78) was observed in urban areas. As for breast cancer, a stable trend (AAPC: 0.3%, 95% CI − 0.3 to 0.9%, P = 0.28) was observed in rural areas compared to a decreasing trend (AAPC: − 2.7%, 95% CI − 4.6 to − 0.7%, P = 0.007) in urban areas. Urban–rural differences in mortality rates increased over time for cervical cancer but decreased for breast cancer. Mortality trends for both cervical and breast cancers showed an increase with age across 4 segments, with the most significant surge in mortality observed among the 35–54 age group across urban and rural areas, periods, and regions in China. Conclusions: Special attention should be given to women aged 35–54 years due to mortality trends and rural–urban disparities. Focusing on vulnerable age groups and addressing rural–urban differences in the delivery of cancer control programs can enhance resource efficiency and promote health equity. [ABSTRACT FROM AUTHOR]

Background: Persistent infection with high-risk human papillomavirus (HR-HPV) plays a key role in the onset of cervical cancer. This study was designed to examine the epidemiological trends and genotype distribution of HPV from 2014 to 2023 in the plateau region of Southwest China. Methods: The findings could offer valuable insights for clinical screening of cervical cancer and the formulation of HPV vaccination policies. This retrospective study analyzed 66,000 women who received HPV-DNA testing at the First People's Hospital of Qujing, Yunnan, China, between 2014 and 2023. The cohort consisted of 33,512 outpatients, 3,816 inpatients, and 28,672 individuals undergoing health examinations. Cervical cells were collected for DNA extraction, and PCR amplification along with Luminex xMAP technology were used to detect 27 HPV genotypes. The data analysis was conducted using GraphPad Prism and IBM SPSS Statistics 27 software. Results: The overall HPV infection rate at the First People's Hospital of Qujing declined from 24.92% in 2014 to 16.29% in 2023, averaging 16.02%. Specific infection rates were 18.50% among outpatients, 12.97% among inpatients, and 13.53% for health examination attendees. The predominant high-risk HPV genotypes identified were HPV52 (2.61%), HPV16 (2.06%), HPV58 (1.81%), HPV53 (1.55%), and HPV39 (1.09%). Meanwhile, the most frequent low-risk HPV genotypes were HPV6 (1.30%), HPV61 (1.21%), and HPV11 (0.85%). In HPV-positive cases, the distribution of single, double, triple, and quadruple or more infections were 79.90%, 15.17%, 3.59%, and 1.33%, respectively. The proportions of pure LR-HPV, pure HR-HPV, and mixed infections were 22.16%, 67.82%, and 10.02%, respectively. Age-specific analysis revealed a bimodal distribution of HPV infection, with the infection rate rapidly decreasing from 44.02% in the ≤ 19 age group to 19.55% in the 20–29 age group and 13.84% in the 30–39 age group, followed by a gradual increase to 14.64% in the 40–49 age group, 16.65% in the 50–59 age group, and 22.98% in the ≥ 60 age group. The coverage rates of the three available vaccines are all below 50%. The results of this study indicated a declining trend in HPV prevalence in the plateau region of Southwest China over the period from 2014 to 2023, especially in the reduction of genotypes targeted by vaccines. Conclusion: There were significant variations in the genotypes prevalent among different age groups, years, and patient sources within the same region. The underwhelming vaccination rates emphasize the critical need for developing either a multivalent vaccine or a personalized vaccine that targets the HPV genotypes common in the Chinese population. Furthermore, vaccinating adolescents to curb HPV infection and ensuring regular cervical cancer screenings for postmenopausal women are crucial steps. [ABSTRACT FROM AUTHOR]

Adolescence involves a period of swift change, including the development of personality vulnerabilities (i.e., dependency and self-criticism) that act as transdiagnostic factors to psychopathology. Over the past several decades, numerous short revisions have condensed the Depressive Experiences Questionnaire (DEQ) into more efficient measures of personality vulnerability. Prior research has investigated the psychometric properties of the short DEQs in adult and clinical samples. However, there has been insufficient exploration within adolescents, who are in addition marked by fluctuating personality vulnerabilities. A representative large sample of adolescents and emerging adults in China aged 10 to 25 (N = 23,953) was administered five short DEQs, including the Revised DEQ (RevDEQ), Reconstructed DEQ (RecDEQ), Theoretical DEQ-21/12 (TDEQ-21/12) and adolescent DEQ (DEQ-A). The data was evaluated for internal consistency and criterion-related validity, while factor structure and measurement invariances across gender and age groups were analyzed by confirmatory factor analysis (CFA). A subset of the original sample (N = 2874) was retested after six months and analyzed for test-retest reliability and cross-time invariance. CFA of the TDEQ-21/12 and RecDEQ supported the intended two-factor model. Good criterion-related validity, internal consistency and test-retest reliability for these three versions were found. Satisfying measurement invariances across gender, time, and age groups were established. The study's scope was confined to non-clinical adolescent populations within China, highlighting a gap in cross-cultural and clinical applicability. The present study supports the use of the TDEQ-21/12 and RecDEQ as valid and concise instruments for measuring Chinese adolescent personality vulnerability. • Four of the short DEQs have acceptable internal consistency and test-retest reliability. • The RecDEQ and TDEQ-21/12 provide good fit for a two-factor personality vulnerability model in adolescents. • The RecDEQ and TDEQ-21/12 have satisfying measurement invariances across gender, time, and age groups. • Criterion-related validity supports a transdiagnostic understanding of personality vulnerability. [ABSTRACT FROM AUTHOR]

The Internet, while offering convenience, can also have negative impacts on learning and quality of life. Previous studies have demonstrated a negative correlation between pathological Internet use and academic performance, but the nature of this relationship in relation to development remains unclear. Utilizing a large sample, the current study aimed to compare the incidence of problematic Internet use across different age groups and explore how the correlation between problematic Internet use and math performance varies with the age of students. Cluster random sampling was used to distribute questionnaires to students in a city in eastern China. A total of 17,208 fourth-grade students (age: M = 9.79, SD = 0.44) and 11,127 eighth-grade students (age: M = 13.65, SD = 0.54) participated in this study. They were asked to complete the Pathological Internet Usage Scale and several math-achievement tests. The results revealed that: (1) A smaller proportion of upper-grade students exhibited problematic Internet use compared to lower-grade students; (2) There was a significant negative correlation between problematic Internet use and math performance; and (3) This correlation was less pronounced among older student.These results suggest that the negative correlation between problematic Internet use and math achievement decreases with age, and this reduced correlation may be linked to increased academic stress. As Chinese students advance in grades, their academic responsibilities become more burdensome, leading to reduced Internet usage. The findings of this study aim to provide insights into enhancing the academic performance of students with problematic Internet use through environmental education interventions. [ABSTRACT FROM AUTHOR]

Introduction: Estimates for cause-specific mortality for neonates are generally available for all countries for neonates overall (0 to 28 days). However, cause-specific mortality is generally not being estimated at higher age resolution for neonates, despite evidence of heterogeneity in the causes of deaths during this period. We aimed to use the adapted log quadratic model in a setting where verbal autopsy was the primary means of determining cause of death. Methods: We examined the timing and causes of death among a cohort of neonates in rural Nepal followed as part of the Nepal Oil Massage Study (NOMS). We adapted methods defined by Wilmoth et al (2012) and Guillot et al. (2022) to estimate age and cause-specific mortality among neonates. We used cross validation to estimate the accuracy of this model, holding out each three month period. We took the average cross validation across hold out as our measure of model performance and compared to a standard approach which did not account for the heterogeneity in cause-specific mortality rate within this age group. Results: There were 957 neonates in the NOMS cohort with known age and cause of death. We estimated an average cross-validation error of 0.9 per 1000 live births for mortality due to prematurity in the first week, and 1.1 for mortality due to birth asphyxia, compared to the standard approach, having error 7.4 and 7.8 per 1000 live births, respectively. Generally mortality rates for less common causes such as congenital malformations and pneumonia were estimated with higher cross-validation error. Conclusions: The stability and precision of these estimates compare favorably with similar estimates developed with higher quality cause-specific mortality surveillance from China, demonstrating that reliably estimating causes of mortality at high resolution is possible for neonates in low resources areas. [ABSTRACT FROM AUTHOR]

Background: Burns cause serious physical and psychological harm to patients, placing a heavy burden on the global healthcare system. Our previous study detailed the epidemiological characteristics of burn injuries in Chinese inpatients from 2009 to 2018. Interestingly, the anatomic locations of burn injuries vary by gender, age, provinces, and outcomes among different causes. Therefore, this current study aims to analyze the characteristics of burn injuries in inpatients with various burn sites by collecting data in China from 2009 to 2018. This analysis will inform future healthcare system decisions and provide effective strategies. Methods: Burns inpatients from 196 hospitals across 31 provinces in China were included in the study, covering the period from 2009 to 2018. The data collected encompassed information on gender, age, etiology, regions, clinical outcomes, and anatomical locations of the injuries. Data analysis was conducted using Microsoft Excel 2007. Results: From 2009 to 2018, a total of 333,995 burns inpatients were recorded. The most vulnerable parts to burns were multiple burn sites (230,090, 68.89%). Women were more susceptible to lower limb burns (15,608, 14%), while men were more prone to eye injuries (8,387, 3.37%) and hand burns (6,119, 2.75%). The age group of 0–10 years was the most vulnerable to burns across all body areas, including internal organs. In China, individuals aged 20–50 years were at a higher risk of head and neck burns compared to other age groups. The Han population showed increased vulnerability to eye injuries (2.12 times higher than minorities), respiratory tract issues (2.09 times higher than minorities), and trunk burns (1.83 times higher than minorities), while being less susceptible to internal organ injuries (0.23 times fewer than minorities) and lower limb burns (0.78 times fewer than minorities). The southwest region had the highest proportion of burns inpatients with burns affecting single body parts, whereas the eastern area had the highest rates of respiratory tract burns (0.85%) and multiple burn sites (80.64%). Scalding was identified as the most common cause of burns, while flame burns (769, 55.81%) and chemical burns (438, 47.35%) were the main causes of respiratory tract and internal organ injuries, respectively. Conclusions: This study provides an initial description of characteristics of burns inpatients with various anatomic locations of burns in China over the past decade. Our findings will contribute to the most up-to-date clinical evidence database for healthcare planning and prevention initiatives in both China and other countries. [ABSTRACT FROM AUTHOR]

Background: Blood plays an irreplaceable role in medical care. Low retention rate among blood donors is the major issue in China. Various functional motivations can encourage blood donors to participate in blood donation. Therefore, it is necessary to conduct research studies on re‐donate behavior based on functional motivations. This study aimed to evaluate the impact of social media intervention based on functional motivation, to discover effective intervention methods to improve re‐donate rate among nonregular blood donors. Methods: In 2022–2023, 726 adults aged 18–55 years were randomized into the intervention or control group. Over 6 months, the intervention group received science popularization via social media. After the follow‐up period, re‐donate rate and functional motivation were assessed. Statistical analyses included t‐test, chi‐square test, logistic regression analysis, and analysis of variance. Results: Five hundred and sixty‐eight participants completed the intervention survey. Overall, the repeat blood donation rate in the intervention group (18.1%) was significantly higher than the control group (4.2%) (p <.001). After the intervention, understanding, protection, sensation, and values motivation increased (p <.001). The changes in functional motivations vary across different age groups. In the 18–30 age group, understanding motivation increased (p <.001), while in the 31–45 and 46–55 age groups, protection motivation increased (p <.001). In the groups donating blood 3 time and 4 time, protection motivation increased (p <.05), and in the group donating blood 4 times, the values motivation increased (p <.05). Conclusion: Social media intervention based on functional motivation can effectively increase the re‐donate rate. Understanding, protection, sensation, and values motivations can directly influence the re‐donate behavior. [ABSTRACT FROM AUTHOR]

Background: Dementia affects 55 million people worldwide and low muscle mass may be associated with cognitive decline. Mid-arm muscle circumference (MAMC) correlates with dual-energy Xray absorptiometry and bioelectrical impedance analyses, yet are not routinely available. Therefore, we examined the association between MAMC and cognitive performance in older adults. Methods: We included community-dwelling adults ≥55 years from the China Health and Nutrition Survey. Cognitive function was estimated based on a subset of the modified Telephone Interview for Cognitive Status (0-27, low-high) during years (1991, 1993, 1997, 2000, 2004, 2006, 2009, 2011, 2015, 2018). A multivariable linear mixed-effects model was used to test whether MAMC was associated with rate of cognitive decline across age groups and cognitive function overall. Results: Of 3702 adults (53% female, 63.2 ± 7.3 years), mean MAMC was 21.4 cm ± 3.0 and baseline cognitive score was 13.6 points ± 6.6. We found no evidence that the age-related rate of cognitive decline differed by MAMC (P =.77). Declines between 5-year age groups ranged from −.80 [SE (standard error).18] to −1.09 [.22] for those at a mean MAMC, as compared to −.86 [.25] to −1.24 [.31] for those at a 1 MAMC 1 standard deviation above the mean. Higher MAMC was associated with better cognitive function with.13 [.06] higher scores for each corresponding 1 standard deviation increase in MAMC across all ages. Conclusion: Higher MAMC at any age was associated with better cognitive performance in older adults. Understanding the relationship between muscle mass and cognition may identify at-risk subgroups needing targeted interventions to preserve cognition. [ABSTRACT FROM AUTHOR]

In the era of the digital society, information has experienced rapid development, and individuals, including the elderly, are increasingly relying on various media to access the information they require. However, there has been limited research on how media usage as a behavior influences the subjective perceptions of older adults and the motivating factors driving their use of media in the digital age. Drawing on the activity theory and knowledge-gap theory, this study aims to investigate whether media use mediates the connection between social participation and subjective well-being among older adults in China. The study also pays specific attention to potential intergroup differences, such as age-group relationships and the types of media involved. We selected a nationally representative sample comprising 938 older adults aged 60 and above from the 2021 Chinese General Social Survey and incorporated them into the mediation analysis. Structural equation modeling (SEM) with path analysis and maximum likelihood procedures was used to analyze the data. Our findings revealed a positive association between social participation and media use, as well as a positive association between media use and subjective well-being. The path analysis further demonstrated that media use mediated the relationship between social participation and subjective well-being. Specifically, social participation through media use, acting as a mediating variable, accounting for 75.3% of the influence on subjective well-being. Distinct age groups exhibited significantly varied levels of social participation, with traditional media (paper-based) playing a more substantial role in our model compared to electronic media (such as television, radio, internet, social media, and mobile applications). The results suggest that older adults with a higher frequency of social participation exhibit stronger levels of media use, and high levels of media use are associated with elevated levels of subjective well-being. The results of this study highlight the positive indirect effects of social participation, media use, and subjective well-being, emphasizing the intricate interplay between these factors among older adults in China. [ABSTRACT FROM AUTHOR]

"Exercise is the best medicine" is well known, but the optimal dose of physical activity (PA) for males and females across different age groups is still unknown. This study, using data from the four waves of CHARLS, aimed to determine the optimal PA dose that reduces frailty risks among older adults across various age groups and both sexes. We created a frailty index score using 63 health-related variables and used 0.21 as the frailty cut point. Binary logistic regression was used to compare the effect of vigorous, moderate, and light intensity PA under IPAQ criteria on frailty risk. The study found that regardless of whether males or females, the optimal effect of vigorous-intensity PA in reducing the risk of frailty is consistently observed throughout the entire old age career. Moreover, the age groups at which moderate-intensity PA reduces the risk of frailty were from age 70 for males and from age 80 for females. And light-intensity PA had no effect on reducing the risk of frailty. Moderate and vigorous intensity of PA in older adults should be promoted, but guidelines and recommendations must account for optimal associations with PA dose across genders and age groups. [ABSTRACT FROM AUTHOR]

Objectives: The aims of this study were to explore the incidence characteristics and trend prediction of lymphoma from 2005 to 2035, and to provide data basis for the prevention and control of lymphoma in China. Method: The data on lymphoma incidence in China from 2005 to 2017 were obtained from the Chinese Cancer Registry Annual Report. The Joinpoint regression model was used to calculate annual percentage change (APC) and average annual percentage change (AAPC) to reflect time trends. Age–period– cohort models were conducted to estimate age, period, and cohort effects on the lymphoma incidence. A Bayesian age–period–cohort model was used to predict lymphoma incidence trends from 2018 to 2035. Results: From 2005 to 2017, the incidence of lymphoma was 6.26/100,000, and the age-standardized incidence rate (ASIR) was 4.11/100,000, with an AAPC of 1.4% [95% confidence interval (CI): 0.3%, 2.5%]. The ASIR was higher in men and urban areas than in women and rural areas, respectively. The age effect showed that the incidence risk of lymphoma increased with age. In the period effect, the incidence risk of lymphoma in rural areas decreased first and then increased with 2010 as the cutoff point. The overall risk of lymphoma incidence was higher in the cohort before the 1970–1974 birth cohort than in the cohort after. From 2018 to 2035, the lymphoma incidence in men, women, and urban areas will show an upward trend. Conclusion: From 2005 to 2017, the incidence of lymphoma showed an increasing trend, and was different in regions, genders, and age groups in China. It will show an upward trend from 2018 to 2035. These results are helpful for the formulation and adjustment of lymphoma prevention, control, and management strategies, and have important reference significance for the treatment of lymphoma in China. [ABSTRACT FROM AUTHOR]

Background: Few articles have focused on the cytological misinterpretation of high-grade squamous intraepithelial lesion (HSIL). Due to estrogen deficiency, cervical epithelial cells in postmenopausal women tend to show atrophic change that looks like HSIL on Papanicolaou-stained cytology slides, resulting in a higher rate of cytological misinterpretation. P16INK4a immunocytochemical staining (P16 cytology) can effectively differentiate diseased cells from normal atrophic ones with less dependence on cell morphology. Objective: To evaluate the role of P16 cytology in differentiating cytology HSIL from benign atrophy in women aged 50 years and above. Methods: Included in this analysis were women in a cervical cancer screening project conducted in central China who tested positive for high-risk human papillomavirus (hrHPV) and returned back for triage with complete data of primary HPV testing, liquidbased cytology (LBC) analysis, P16 immuno-stained cytology interpretation, and pathology diagnosis. The included patients were grouped by age: ≥50 (1,127 cases) and <50 years (1,430 cases). The accuracy of LBC and P16 cytology in the detection of pathology ≥HSIL was compared between the two groups, and the role of P16 immunostain in differentiating benign cervical lesions from cytology ≥HSIL was further analyzed. Results: One hundred sixty-seven women (14.8%; 167/1,127) in the ≥50 group and 255 (17.8%, 255/1,430) in the <50 group were pathologically diagnosed as HSIL (Path-HSIL). LBC [≥Atypical Squamous Cell Of Undetermined Significance (ASCUS)] and P16 cytology (positive) respectively detected 63.9% (163/255) and 90.2% (230/255) of the Path-≥HSIL cases in the <50 group and 74.3% (124/167) and 93.4% (124/167) of the Path-≥HSIL cases in the ≥50 group. LBC matched with pathology in 105 (41.2%) of the 255 Path-≥HSIL cases in the <50 group and 93 (55.7%) of the 167 Path-≥HSIL cases in the ≥50 group. There were five in the <50 group and 14 in the ≥50 group that were Path-≤LSIL cases, which were interpreted by LBC as HSIL, but negative in P16 cytology. Conclusion: P16 cytology facilitates differentiation of Path-≤LSIL from LBC-≥HSIL for women 50 years of age and above. It can be used in the lower-resource areas, where qualified cytologists are insufficient, as the secondary screening test for women aged ≥50 to avoid unnecessary biopsies and misinterpretation of LBC primary or secondary screening [ABSTRACT FROM AUTHOR]

The Changning-Menglian suture zone is a critical tectonic belt pivotal to the evolution of the Paleo-Tethys. The Wenquan Formation, characterized as turbidite deposited on the western side of the Changning-Menglian suture zone as well as the eastern edge of the Baoshan Block. Analysis of detrital zircons from the Wenquan Formation reveals two significant age peaks approximately at 440 and 980 Ma, with additional age populations around 600, 780, and 2 500 Ma. The major age peak at about 440 Ma is come from the andesitic-dominant volcanic arc within the Lancang Block and the western Simao Block, corroborated by the presence of andesite fragments in thin section studies. Meanwhile, the zircons that form the secondary age peak at ∼980 Ma and other older age groups probably originate from the Baoshan Block. Deposited on the western side of the Paleo-Tethyan ophiolites, the Wenquan Formation received detrital materials from the continental margin on the opposite side. Thus, the main Paleo-Tethyan Ocean basin was not sufficiently broad enough to cut off the transference of detrital materials. It was a relatively narrow basin in the Early Devonian. [ABSTRACT FROM AUTHOR]

Clinical guidelines recommend the use of statins in the primary prevention of cardiovascular disease. However, there is uncertainty about the benefit of statin therapy in adults older than 75 years. This is in part due to the underrepresentation of this age group in published statin trials. The aim of this study is to evaluate the long-term effectiveness and safety of using statins for primary prevention of cardiovascular disease in adults older than 75 years. Visual Abstract. Benefits and Risks Associated With Statin Therapy for Primary Prevention in Old and Very Old Adults: Clinical guidelines recommend the use of statins in the primary prevention of cardiovascular disease. However, there is uncertainty about the benefit of statin therapy in adults older than 75 years. This is in part due to the underrepresentation of this age group in published statin trials. The aim of this study is to evaluate the long-term effectiveness and safety of using statins for primary prevention of cardiovascular disease in adults older than 75 years. Background: There is little consensus on using statins for primary prevention of cardiovascular diseases (CVDs) and all-cause mortality in adults aged 75 years or older due to the underrepresentation of this population in randomized controlled trials. Objective: To investigate the benefits and risks of using statins for primary prevention in old (aged 75 to 84 years) and very old (aged ≥85 years) adults. Design: Sequential target trial emulation comparing matched cohorts initiating versus not initiating statin therapy. Setting: Territory-wide public electronic medical records in Hong Kong. Participants: Persons aged 75 years or older who met indications for statin initiation from January 2008 to December 2015 were included. Participants with preexisting diagnosed CVDs at baseline, such as coronary heart disease (CHD), were excluded from the analysis. Among 69 981 eligible persons aged 75 to 84 years and 14 555 persons aged 85 years or older, 41 884 and 9457 had history of CHD equivalents (for example, diabetes) in the respective age groups. Intervention: Initiation of statin therapy. Measurements: Incidence of major CVDs (stroke, myocardial infarction, or heart failure), all-cause mortality, and major adverse events (myopathies and liver dysfunction). Results: Of 42 680 matched person-trials aged 75 to 84 years and 5390 matched person-trials aged 85 years or older (average follow-up, 5.3 years), 9676 and 1600 of them developed CVDs in each age group, respectively. Risk reduction for overall CVD incidence was found for initiating statin therapy in adults aged 75 to 84 years (5-year standardized risk reduction, 1.20% [95% CI, 0.57% to 1.82%] in the intention-to-treat [ITT] analysis; 5.00% [CI, 1.11% to 8.89%] in the per protocol [PP] analysis) and in those aged 85 years or older (ITT: 4.44% [CI, 1.40% to 7.48%]; PP: 12.50% [CI, 4.33% to 20.66%]). No significantly increased risks for myopathies and liver dysfunction were found in both age groups. Limitation: Unmeasured confounders, such as lifestyle factors of diet and physical activity, may exist. Conclusion: Reduction for CVDs after statin therapy were seen in patients aged 75 years or older without increasing risks for severe adverse effects. Of note, the benefits and safety of statin therapy were consistently found in adults aged 85 years or older. Primary Funding Source: Health Bureau, the Government of Hong Kong Special Administrative Region, China, and National Natural Science Foundation of China. [ABSTRACT FROM AUTHOR]

Background: With the appearance and aggravation of the aging society, cancer has become one of the major problems that threaten the life and health of Chinese residents seriously. Objective: To explore the cancer epidemiological characteristics among the elderly in China from 2005 to 2016, and to provide strategies for cancer prevention and treatment. Methods: Stratified analysis was conducted on the cancer mortality data of the elderly aged ≥60 years in China, which were selected from the Chinese Cancer Registry Annual Report. Joinpoint regression model was used to calculted average annual percentage change (AAPC) to estimate the time trends. Age-period-cohort (APC) model was used to explore the age, period and birth cohort effect on the risk of cancer death. Bayesian age-period-cohort (BAPC) model was used to predict trends in cancer mortality among elderly by gender and region to 2035. Results: 2005–2016, cancer mortality in the elderly in China showed a decreasing trend (AAPC = -1.2%, P<0.001). Cancer mortality in rural areas was higher than that in urban areas, but the urban-rural difference gradually narrowed (t = 6.1, P<0.01). The APC model showed that cancer mortality increased with age. The relative risk (RR) for the period effect decreased. RR was lower for the later- born cohort than that for the earlier-born cohort in rural areas. Lung cancer mortality ranked first in both male and female, and showed an increasing trend among female in the 60–64, 80–84 and ≥85 age groups (AAPC60-64 = 1.0%, AAPC80-84 = 0.8%, AAPC≥85 = 2.0%, all P<0.05). By 2035, cancer mortality for the elderly was predicted to decline nationally, by sex and in rural areas, while rising in urban areas. Conclusion: Cancer mortality in the elderly in China showed a decreasing trend from 2005 to 2016, but it was still higher than the world average. Early cancer screening is important, especially in the elderly male and in rural areas. [ABSTRACT FROM AUTHOR]

Background: The health condition during childhood has been shown to influence an individual's health and socioeconomic status in adulthood. Understanding the concentration and persistence patterns in children's healthcare expenditures is crucial for providing risk protection and promoting the well-being of children. Studies regarding the concentration and persistence of health expenditures have focused mainly on elderly individuals in developed regions. To gain insights into factors that contribute to childhood health expenditures, this article examined children with high costs (that is, in the top 10% of the expenditure distribution) and explored the characteristics and spending patterns that distinguished them from other patients in the context of the largest developing economy—China. Methods: By using a unique individual-level administrative claims dataset over a 5-year observation period, this study identified spending concentrations and the proportion of children whose costs remained high over five years using a linear probability model and logit regression analysis. Results: Teenagers from 12 to 17 years old were more likely to persist in the high-cost group than any other age groups in the study. Pediatric complex chronic conditions and other severe health ailments were predictive factors for entry into and persistence in the high-cost category. More than half of the total health expenditures were attributed to children in the top 10% expenditure group. In addition, risk protection and healthcare insurance support for high-cost children was found to be inadequate, particularly for children from low-income families. Conclusions: Healthcare support for children impacts individual development and family financial status. This study described the characteristics and spending patterns of children patients in the largest developing country. The fact that over half of total expenditures are concentrated toward 10% of patients makes it valuable to consider relevant support for this group, especially for families whose medical costs are higher than income. [ABSTRACT FROM AUTHOR]

Regional population mortality correlates with regional socioeconomic development. This study aimed to identify the key socioeconomic factors influencing mortality patterns in Chinese provinces. Using data from the Seventh Population Census, we analyzed mortality patterns by gender and urban‒rural division in 31 provinces. Using a functional regression model, we assessed the influence of fourteen indicators on mortality patterns. Main findings: (1) China shows notable gender and urban‒rural mortality variations across age groups. Males generally have higher mortality than females, and rural areas experience elevated mortality rates compared to urban areas. Mortality in individuals younger than 40 years is influenced mainly by urban‒rural factors, with gender becoming more noticeable in the 40–84 age group. (2) The substantial marginal impact of socioeconomic factors on mortality patterns generally becomes evident after the age of 45, with less pronounced differences in their impact on early-life mortality patterns. (3) Various factors have age-specific impacts on mortality. Education has a negative effect on mortality in individuals aged 0–29, extending to those aged 30–59 and diminishing in older age groups. Urbanization positively influences the probability of death in individuals aged 45–54 years, while the impact of traffic accidents increases with age. Among elderly people, the effect of socioeconomic variables is smaller, highlighting the intricate and heterogeneous nature of these influences and acknowledging certain limitations. [ABSTRACT FROM AUTHOR]

Although the SNARC effects in symbolic numerals and non-symbolic numerosity have been observed in different studies, little is known about their developmental trajectory and potential relationship. The present study aims to explore the development of the symbolic and non-symbolic SNARC effects across different age groups, and further examine the relationship between these two SNARC effects. Experiment 1 measured 36 6-to-7-year-old children, 59 7-to-8-year-old children, 69 8-to-9-year-old children, and 31 adults from China using parity judgment tasks. The results showed that the non-symbolic SNARC effect emerged in all age groups. While, the symbolic SNARC effect only emerged in 8-to-9-year-old children as well as adults. Experiment 2 measured 53 6-to-7-year-old children, 83 7-to-8-year-old children, 85 8-to-9-year-old children, as well as 31 adults from China with the magnitude comparison tasks. We found that both the symbolic and non-symbolic SNARC effects emerged in 7-to-8-year-old children, 8-to-9-year-old children as well as adults. Both experiments showed that for children and adults with significant symbolic SNARC effects and non-symbolic SNARC effects, the size of these two SNARC effects did not show significant differences. In addition, these two SNARC effects were both dissociated in two types of tasks. These findings are important for clarifying how symbolic and non-symbolic spatial-numerical associations develop. [ABSTRACT FROM AUTHOR]

In China suicide rates have been declining for about three decades. Patterns of suicide for women and men across the lifespan over time however have not been systematically documented. Official suicide mortality data (from 1990 to 2017) available via China CDC were used to examine suicide patterns by gender and age in each of the 33 provincial-level regions. Suicide data were aggregated by five years, except for the year of 2017. The bar graphs were used to descriptive the change tread of the suicide rate. In the past three decades, the decline in female suicide rates was greater than that in the male rates, with the overall male to female (M/F) ratio changing from 0.88 in 1996 to 1.56 in 2017. The overall suicide rate of male was 8.82 and female was 5.65 per 100,000 persons in 2017. However the decline of suicide rates for people aged 70 and older was the greatest declination (33.73/per 100,000 persons) among all the age groups in China. Overall suicide rates have declined over the three decades in China, particularly among females and individuals age 70+ years. Suicide rates continue to be higher among individuals aged 50 and older (particularly among men), and this population should continue to the focus for prevention. • Data is officially from China CDC from 1990 to 2017, almost three decades. • Four age groups were investigated. • Gender ratios were analyzed to learn more of the trajectories of the changes. • Study discussed the unique reasons of suicide in china, which offer important implications in suicide prevention in the world. [ABSTRACT FROM AUTHOR]