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Lee, T.H.; Oh, H.Y.; Kim, K.-D., and Kim, H.S., 2023. Yacon juice residue supplementation in low fish meal diet for black rockfish (Sebastes schlegelii). In: Lee, J.L.; Lee, H.; Min, B.I.; Chang, J.-I.; Cho, G.T.; Yoon, J.-S., and Lee, J. (eds.), Multidisciplinary Approaches to Coastal and Marine Management. Journal of Coastal Research, Special Issue No. 116, pp. 538-542. Charlotte (North Carolina), ISSN 0749-0208. This sudy evaluated the effects of Yacon Juice Residue (YJR) on the growth performance, lysozyme and antioxidant enzyme activities, and disease resistance against Streptococcus iniae of juvenile black rockfish (Sebastes schlegelii) fed a low Fish Meal (FM) diet supplemented with soy and corn protein concentrates. We considered a 60% FM-based diet as a High FM (HF) diet; and a diet in which 30% FM was substituted with a mixture of soy and corn protein concentrates was considered a Low FM (LF) diet. Another six experimental diets, prepared in triplicate, consisted of the LF diet supplemented with YJR at levels of 2.5 g/kg, 5 g/kg, and 10 g/kg (designated as LFY2.5, LFY5, and LFY10 diets, respectively). At the end of the 8-week feeding trial, the highest growth performance (final body weight, weight gain and specific growth rate) was observed in fish fed with the HF diet. Furthermore, fish fed the LFY5 and LFY10 diets had significantly higher growth performances than fish fed the LF diet. All the dietary treatments had similar feed efficiency. Higher lysozyme activity were observed in fish fed the HF and LFY10 diets compared to fish fed the other diets. Plasma superoxide dismutase and catalase activities of the LF diet were significantly enhanced by dietary YJR supplementation. Disease resistance of fish against S. iniae was significantly improved by dietary YJR. The findings demonstrate that supplementing the diet with YJR can partially mitigate growth retardation associated with a diet high in soy and corn protein concentrates, as well as enhance fish antioxidant capacity and disease resistance. [ABSTRACT FROM AUTHOR]