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In patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention, contrast-induced nephropathy (CIN) is a serious complication associated with poor outcomes. We assessed the predictive value of the Canada Acute Coronary Syndrome (C-ACS) score for CIN in these patients. A total of 394 consecutive patients with STEMI were enrolled and divided into 3 groups according to their C-ACS scores--group 1, score 0; group 2, score 1; and group 3, score ≥2. The clinical outcomes were CIN and major adverse clinical events (MACEs) during hospital and follow-up; 8.4% of patients developed CIN. Patients with high C-ACS scores were more likely to develop CIN, in-hospital death, and MACEs (P < .001). The C-ACS score was an independent predictor of CIN (odds ratio = 2.87; 95% confidence interval = 1.78-4.63; P < .001) and risk factor for long-term MACEs. The C-ACS score had good predictive values for CIN, in-hospital morality, MACEs, and long-term mortality. Patients with high C-ACS risk scores exhibited a worse survival rate than those with low scores (death, P = .02; MACEs, P = .006). In conclusion, in patients with STEMI, the C-ACS could predict CIN and clinical outcomes. [ABSTRACT FROM AUTHOR]

The Arctic is rapidly warming posing a significant threat to underlying permafrost. Permafrost degradation has already resulted in extensive damage to the Arctic's built infrastructure, putting communities and industries at risk. Projected climate warming will further reduce the capacity of permafrost to support infrastructure, thereby requiring a rethinking of construction and development of permafrost regions in the future. This paper focuses on three Arctic regions with a substantial presence of population and infrastructure on permafrost: USA (Alaska), Canada, and Russia. The three regions' permafrost construction practices are examined in order to identify best practices and major gaps. We identify a lack of standardized, codified construction guidelines; an absence of permafrost-geotechnical monitoring in communities; barriers to integrating climate scenarios into future planning; limited data sharing; and low numbers of permafrost professionals as major constraints limiting the region's resilience in the face of climate change. Refining building practices and standards, implementing operational permafrost monitoring systems, developing downscaled climate projections, and integrating local knowledge will minimize the impacts of permafrost degradation under rapidly warming climatic conditions., (© 2023. The Author(s) under exclusive licence to Royal Swedish Academy of Sciences.)

Large industrial projects change communities, landscapes, and ecosystems, with significant impacts for local people. But, conventional project evaluations often underestimate wide-ranging local interests, especially those of young people. To address this gap, we collected data from Instagram, where a younger demographic dominates the medium, focusing on two hydroelectricity proposals in Canada: the in-progress Site C Dam in British Columbia, and the 1960s Mactaquac Dam in New Brunswick. A year of landscape photos and captions from each were coded into thematic categories and linked based on statistical co-occurrence. Project impacts for this youth cohort can be predicted by identifying the values and activities statistically associated with the features likely to be affected by each proposal: dam construction will affect perceived esthetics and sense of home in Site C, and dam removal will cause lifestyle changes in Mactaquac. The advantages and drawbacks of this method are discussed including implications of such new data sources for social impact assessment. [ABSTRACT FROM AUTHOR]

The purpose of this study was to understand the volunteer legacy of a major sport event and identify aspects of the event that shaped future voluntary action in the host community. Social exchange theory framed the examination of volunteers' positive and negative experiences with the event as a predictor of future behavioral intentions. A total of 1098 volunteers involved with the 2001 Canada Summer Games completed a post-event survey. In general, planning volunteers' future volunteering was particularly influenced by experienced costs of the event (task overload, personal inconvenience), although contributing to the community and a positive life experience were also predictive of their future involvement. In contrast, on-site volunteers' future volunteering was more influenced by experienced benefits of the event, including social enrichment, community contribution, and a positive life experience. However, personal inconvenience and task underload were also predictive of their future involvement. The findings have implications for event policy and management that should acknowledge the potential for major sport events to engender a legacy of volunteering. [ABSTRACT FROM AUTHOR]