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Interdisciplinary collaboration fuels research innovation and funders are increasingly offering long-term grants prioritising partnerships. However, a gap remains regarding the effective development, evaluatation, and sustainment of research partnerships; particularly those supporting marginalised populations like sexual and gender minority youth (SGMY). There is a concomitant need to expand research internationally to cross-culturally conceptualise SGMY's experiences, which information and communication technologies (ICTs) may facilitate. The International Partnership for Queer Youth Resilience (INQYR) is a research consortium comprising over 40 academic and community representatives investigating and addressing issues faced by SGMY in Canada, the United Kingdom (UK), United States of America (USA), and Mexico from an interdisciplinary perspective by: (a) conducting and disseminating interventions and exploratory research on SGMY's ICT use, and (b) training cohorts of SGMY scholars and practitioners. This article details INQYR's rationale and formation, including its objectives and organisational framework. Facilitators and barriers are discussed through reflection on INQYR's first operational phase from 2018–2021, considering collaboration with diverse stakeholders and settings; shared goals; language and technology barriers; personal and workload barriers; infrastructure; and power and historical tensions. Implications for other research partnerships and concrete tools such as author guidelines for large-scale research partnership formation, operation, and evaluation are discussed. [ABSTRACT FROM AUTHOR]

Bowen and colleagues ask us to re-imagine how to conduct research in academic-practice partnerships, and to develop capacity in the applied research and health workforce to do this. This commentary reinforces their messages, and describes a framework of research capacity development for impact (RCDi) which emphasizes active and continuous experiential learning within research partnerships. The RCDi framework includes the need to focus on multiple levels in the collaboration architecture, and describes principles of working that aims to increase impact on services, and learning opportunities for all partners. [ABSTRACT FROM AUTHOR]