Search

Background: Alcohol mixed with energy drinks (AmED) is linked to deleterious drinking, particularly within college students. However, measurement and methodological concerns complicate a more thorough understanding of how AmED contributes to problematic alcohol consumption. This study examined AmED proportion (i.e., percentage of overall drinking events involving AmED consumption) as a metric for differentiating problematic alcohol use and tested the utility for explaining additional risk of alcohol-related problems beyond overall alcohol involvement. Methods: Self-report data were collected from a diverse sample of AmED consumers from two west-coast U.S. universities (N= 458; 60.1% female; 31.4% White). Participants were divided into three AmED proportion groups: low (25% or less of all drinking events), moderate (about 50%), or high (75% or more), and assessed for overall alcohol use and related consequences. Results: The groups did not differ on demographics or recent alcohol use. However, high proportion users reported significantly more alcohol-related problems than the low and moderate groups, even after controlling for overall alcohol involvement. However, proportion did not differentiate at-risk drinking as measured by cut-scores of the AUDIT. Conclusions: Findings provide support for proportion as metric for differentiating alcohol-related problems within AmED consumers. Implications for future research and interventions were discussed. [ABSTRACT FROM PUBLISHER]

Background: Mixing alcohol with energy drinks is associated with heavier drinking and related problems among college students. However, little is known about how high school drinkers who mix alcohol with energy drinks (AmED) compare to those who do not (AwoED). This study compares high school AmED and AwoED users on their alcohol use during middle and high school, as well as key domains of functioning in high school.Methods: Two surveys were conducted three years apart in adolescents initially recruited from 16 middle schools in Southern California. The analytic sample consists of 696 past month drinkers. Multivariable models compared AmED and AwoED users on alcohol use, mental health, social functioning, academic orientation, delinquency and other substance use at age 17, and on their alcohol use and related cognitions at age 14.Results: AmED was reported by 13% of past month drinkers. AmED and AwoED users did not differ on alcohol use or cognitions in middle school, but AmED users drank more often, more heavily, and reported more negative consequences in high school. AmED users were also more likely to report poor grades, delinquent behavior, substance use-related unsafe driving, public intoxication, and drug use than AwoED users in high school. Group differences were not found on mental health, social functioning, or academic aspirations.Conclusions: AmED use is common among high school drinkers. The higher risk behavioral profile of these young AmED users, which includes drug use and substance use-related unsafe driving, is a significant cause for concern and warrants further attention. [ABSTRACT FROM AUTHOR]

Background Energy drinks have been linked to an increase in emergency room visits and deaths. We aim to determine the impact of energy drinks on electrocardiographic and hemodynamic parameters in young healthy volunteers. Methods and Results A randomized, double-masked, placebo-controlled, crossover study was conducted in healthy volunteers. Participants consumed 32 oz of either energy drink A, energy drink B, or placebo within 60 minutes on 3 study days with a 6-day washout period in between. The primary end point of QT c interval and secondary end points of QT interval, PR interval, QRS duration, heart rate, and brachial and central blood pressures were measured at baseline, and every 30 minutes for 240 minutes. A repeated-measures 2-way analysis of variance was performed with the main effects of intervention, time, and an interaction of intervention and time. Thirty-four participants were included (age 22.1±3.0 years). The interaction term of intervention and time was statistically significant for Bazett's corrected QT interval, Fridericia's corrected QT interval, QT , PR , QRS duration, heart rate, systolic blood pressure, diastolic blood pressure, central systolic blood pressure, and central diastolic blood pressure (all P<0.001). The maximum change from baseline in Bazett's corrected QT interval for drinks A, B, and placebo were +17.9±13.9, +19.6±15.8, and +11.9±11.1 ms, respectively ( P=0.005 for ANOVA ) ( P=0.04 and <0.01, respectively compared with placebo). Peripheral and central systolic and diastolic blood pressure were statistically significantly different compared with placebo (all P<0.001). Conclusion Energy drinks significantly prolong the QT c interval and raise blood pressure. Clinical Trial Registration URL : http://www.clinicaltrials.gov . Unique identifier: NCT03196908.