1. Retrospective Analysis of Treatment Modalities and Survival of Patients with Cervical Cancer in Ain Shams University Maternity Hospital from 2012 to 2017.
- Author
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Elshalakany, A. H., Mamdouh, A. M., and Helal, M. M. O.
- Subjects
WOMEN'S hospitals ,CERVICAL cancer ,UNIVERSITY hospitals ,CANCER patients ,RETROSPECTIVE studies ,CERVIX uteri diseases ,GYNECOLOGIC cancer - Abstract
Background: cervical carcinoma is considered the second most common cause of gynecological malignancy death following ovarian carcinoma. The incidence of invasive cervical cancer is higher in low-income countries due to lack of screening programs. There are many treatments for cervical carcinoma, namely surgery, chemotherapy and radiotherapy with different morbidity and survival rates (also according to the stage of the disease). Aim of the Work: The aim of this work is to review the cervical cancer patients in Ain Shams University Maternity Hospital from 2012 to 2017 in the aspects of demographic characteristics, treatment modalities used, survival and morbidity. Patients and Methods: the data includes patients diagnosed as having cervical cancer from 1-1-2012 to 31-12-2017 in Ain Shams University Maternity Hospital as retrospective analytical study. We collect name, age, parity stages, Histopathology, treatment, morbidity and survival about each woman and analyze this data. Results: study included 147 women diagnosed as having cervical carcinoma from 2012 to 2017 in Ain Shams University Maternity Hospital. the most frequent residence was greater Cairo (81%). Majority of patients and their husbands were illiterate (91.8%). Two thirds of the studied cases were married (66.7%). Less than two thirds of the studied cases were postmenopausal (64.6%). The mean age of cases included in this study was 52.3 years. SSC was the most frequent pathology (82.3%). the overall survival rate was 61.7% (survival duration 1.2year with IQR (1→ 2.5 year). By the end of our study 81.8 % of the cases survived in stage I, 65.7 % in stage II, 55.6 % in stage III and 33.3 in stage IV. The most frequent treatment modality was primary radiotherapy without surgery 53.2% with 60% survival with median duration 1year (0.8-2 year). Then primary radiotherapy with surgery 22.5 % (19.8 % with completion surgery and chemotherapy and 2.7% with salvage surgery) with 56.2 % survival with median duration 1.1 year (1-2.5 year) and the least frequent was 1ry surgery (21.6 %) with 80% survival with median duration 1.8 year (1-3.9 year). Recurrence was in less than tenth of cases (9.3%), the most frequent site was extrapelvic (75.0%). Conclusion: In Ain Shams University Maternity Hospital the cases are usually clinically presented in late stages and usually with complications due to lack of screening. In developing countries like Egypt, brachytherapy may not be available for all patients. Our study proved that completion surgery after whole pelvic radiation can take place with comparable survival rates and morbidity. Our survival rates are comparable with other studies conducted in developed countries and are good with our limited resources but are less than other studies performed in developed countries. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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