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Background: This study investigates the challenges and solutions in implementing Interprofessional Education (IPE) within the nursing curriculum at a Hispanic-Serving Academic Institution in Bronx, New York. Objective: To explore how IPE can bridge gaps in healthcare education by fostering collaboration among students from various disciplines. Methods: The authors developed workshops and simulation cases involving multiple healthcare disciplines to address barriers such as course context differences, faculty workload, institutional barriers, and hierarchical culture in healthcare. Findings: The results showed positive impacts of IPE within the nursing program, with successful collaborations among nursing, social work, speech language and hearing sciences, health services administration, and exercise science students. Conclusions: The study highlights the transformative potential of IPE in healthcare education, emphasizing the need for a multifaceted approach to address individual, faculty, and structural barriers and offering insights for enhancing collaboration, communication, and cultural sensitivity among future healthcare professionals. [ABSTRACT FROM AUTHOR]