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This essay intends to share perspectives that constitute, in multiple and contingent forms, a transfeminist enunciation locus in Latin America. Seeking approximations with decolonial and trans+feminist studies, in their relations with issues of gender identities and expressions, sexualities and bodily diversities, the perspectives we share are related to different geopolitical contexts in the region and, despite a situated emphasis on the Brazilian context, we attempt to delineate epistemic, political, economic and affective closeness for trans, travesti, non-binary lives throughout 'Latin American' territories. We are interested in working, from our travesti anthropofagies (Silva, 2018), with concepts such as decoloniality, cistem-world and cisheteronormativity, instrumentalising them in the sense of a broader transfeminist contribution than one merely linked to the realm of its 'specific issues'. These approximations and interests converge in confronting historical contexts of growing conservatism, both general and specific to issues of gender identities and expressions, sexualities and bodily diversities, while a variety of resistance possibilities emerge across academic, institutional and social movement spheres. We will try to outline, from some episodes in the recent period, some strategies, propositions and confrontations which could be related to transfeminist theories and practices, as well as the political obstacles presented by our regional contexts. [ABSTRACT FROM AUTHOR]