Search

The article explores the role of the "Syndicat du matériel et mobilier scolaire de l'enseignement" in supplying French school materials to several countries, including Mexico, Canada, and Brazil, in order to demonstrate the profitability of a new industry, the school industry, and of a new type of trade, the transnational trade in school artefacts used as didactic resources. It is divided into four parts. The Introduction presents the context in which this commercial activity flourished, favoured by the developments of the second industrial revolution and the new educational guidelines associated with mass schooling and the method of "object lessons". Next, it characterises the enterprise in Brazil, from the presentation of commercial agents operating in the states of Bahia, Rio de Janeiro, and São Paulo to the identification of the strategies mobilised for the sale and importation from France of school artefacts, conceived as merchandise. In the third part the lens is reversed, and the objective is to examine the ways in which purchases were made by the public education administration in São Paulo. As a final comment, the article reaffirms the connections between the values of capitalist society, consumption practices and the material elementary schooling universe between the late nineteenth and early twentieth centuries.

Background: Few studies have evaluated the effects of structured early mobilization (EM) protocols on the level of mobilization in critical care patients. Objective: To evaluate the impact of a structured EM protocol on the level of mobilization, muscle strength, and the level of activities of daily living (LADL) after intensive care unit (ICU) and hospital discharge. Methods: This randomized clinical trial (U1111-1245-4840) included adults patients who were randomized into two groups: intervention (n = 40) and control (n = 45). The intervention group underwent conventional physiotherapy and structured EM protocols, and the control group underwent conventional physiotherapy. The level of mobilization from 0 (no mobilization) to 5 (walking), muscle strength (Medical Research Council scale), LADL (Katz Index), and incidence of complications were evaluated. Results: The level of mobilization from day 1 to day 7 increased in the intervention group compared with the control group (p <.05). Muscle strength did not change during the protocol in the intervention and control groups {day 1 [effect size (r) = 0.15, p =.161], at ICU discharge [r = 0.16, p =.145], and after ICU discharge [r = 0.16, p =.191]}. The LADL did not differ between the intervention and control groups after ICU discharge [4 (1–6) vs. 3 (1–5), p =.702] or 30 days after hospital discharge [6 (5–6) vs. 6 (5–6), p =.945]. The structured EM protocol was safe, and no severe complications were observed during the protocol. Conclusion: A structured EM protocol increased the level of mobilization without improving muscle strength and the LADL compared with conventional physiotherapy. [ABSTRACT FROM AUTHOR]

The aim of this work is to adapt and test, in a Brazilian public school, the ACE model proposed by Borkulo for evaluating student performance as a teaching-learning process based on computational modeling systems. The ACE model is based on different types of reasoning involving three dimensions. In addition to adapting the model and introducing innovative methodological procedures and instruments for collecting and analyzing data, our main results showed that the ACE model is superior than written tests for discriminating students on the top and bottom of the scale of scientific reasoning abilities, while both instruments are equivalent for evaluating students in the middle of the scale.

Copyright of Historia Agraria is the property of Historia Agraria and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Historia Agraria is the property of Historia Agraria and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Aiming to debate the the power of the counter-mobilization that emerged on Twitter during the coronavirus pandemic in Brazil, we carried out a documental study on Twitter collecting texts and images associated with the #BolsonaroGenocida hashtag, between March 13 and June 6 of 2021, a period in which intense public demonstrations took place against the Bolsonaro's government in the country. We analysed 1243 tweets and 503 images, identifying the main contents anchored and objectified by the hashtags, revealing the various dimensions that compose the social representations associated with Bolsonaro and his management during the pandemic. The tweets' contents comprehend the social and political demonstration arising from part of the Brazilian people against the actions taken by the president of Brazil during the Covid-19 pandemic, which led to thousands of deaths that could have been avoided; regarding the images, the results point out an emotional anchoring of Bolsonaro's image to death. It is therefore important to demarcate the nature of Twitter as an specific platform for the mobilization of SR through the sharing of images and texts, which ends up evoking emotions that contribute to accentuating the social identity of the group that is expressed. [ABSTRACT FROM AUTHOR]

Roupala montana var. brasiliensis is a timber tree species native to the Cerrado and Atlantic Forest areas of Brazil. The wood was exploited for international markets, but there is no information on the conservation status of its natural populations, nor on other key aspects, such as mating system, gene flow, and inbreeding depression, essential for the species' sustainable management and conservation. We report the first study of any Roupala species to apply a validated set of species-specific microsatellite markers to genotype adults, juveniles, and seedlings, and analyse genetic diversity, inbreeding, effective population size, and mating system. We studied four populations of the species in areas of mixed Ombrophilous forest with different disturbance levels (undisturbed to strongly disturbed) in southern Brazil. The species occurs at low frequency in the study forests, but the populations are genetically diverse without significant differences in genetic diversity levels related to disturbance. The study also indicated resistance to the severe fragmentation associated with low density of individuals, with a stable mating system showing preferential outcrossing, with some inbreeding (tm ≈ 0.83, F > 0.165). Despite being spatially isolated from each other, the populations are not reproductively isolated, receiving immigrant pollen from long distances, although there was no evidence of gene flow into the populations via seeds. Seedlings from self-fertilization show low levels of inbreeding depression, which may reflect earlier pre-germination selection events. There was loss of allelic wealth in the younger cohorts, which may be a warning of the fragility of the genetic diversity detected in populations. We consider the implications of the results for the development of ex and in situ conservation and tree improvement programs. [ABSTRACT FROM AUTHOR]

Machine learning techniques have been widely used in the oil and gas industry to improve the qualitative and quantitative characterization of subsurface reservoirs. Because rock properties are strongly influenced by lithological and sedimentological information, lithofacies classification is an important step in 3D reservoir modeling. The aim of this study is to use supervised classification algorithms to predict the spatial distribution pattern of lithofacies classes using borehole and seismic data. In this study, lithofacies classes are distributed away from the wells using a machine-learning classifier. Seismic data attributes extracted from well locations are utilized as training data features in various supervised classification algorithms. Machine learning classifiers trained and evaluated for lithofacies classification include K-nearest neighbors, support vector machine, Gaussian naive Bayes, decision tree, Gradient Boosting, and Random Forests. A number of parameters are optimally determined in order to achieve the highest value of classification accuracy in the model. Comparing machine learning classifiers based on evaluation metrics reveals that ensemble-based decision tree approaches such as Random Forests and Gradient Boosting are the most effective for supervised classification. The results are validated using testing data and have an 80% classification accuracy. The predicted volume of lithofacies classes contributes to improved 3D reservoir modeling for the pre-salt carbonate reservoir. [ABSTRACT FROM AUTHOR]

Introduction: Despite the long-lasting efforts to promote the quality of obstetric care, Brazil requires robust changes in the care practices throughout the prenatal-labour-postpartum continuum. The ongoing National Program for the Humanization of Prenatal and Childbirth (PHPN) efforts address the fight against obstetric violence (OV), the improvement in the quality of obstetric care, but its implementation has faced obstacles and difficulties, such as responding to cultural values and operating with a weak infrastructure. This research explored Brazilian health and social service professionals' perceptions of the PHPN's recommendations regarding innovation, policy and practice changes necessary to respect women's human rights to receive a high quality, dignifying obstetric care. Methods: An online multi-site survey in which data were collected (Jun 2019-Mar 2020) from health professionals working in the public health system in Brazil. Data analysis used descriptive statistics and thematic analysis. Analytical themes were Perceptions of Program effectiveness to minimize obstetric violence and Program's gaps, inadequacies and needed changes. Results: Respondents (n=369) disclosed their perceptions about the Program's nature, utility, and gaps towards an improved implementation. Key issues were rooted in the outdated university education, reduced accountability, and governance in services' management; unfavourable work conditions and climate; professional power-imbalance; population's lack of information about the Program; underutilization of obstetric nurses' and midwives' skills; neglect of professional development; no denunciation & re-education, and culture of quality improvement. Conclusions: Firmness, hope and determination will be needed to transform society's culture of silence about OV, awakening the public awareness and mobilizing to enhance collective health and political literacy to ensure professional accountability while protecting women and newborns. There is a need for a realignment of work processes, an investment in professional education, and education within women's social networks for women to become partners in the active process of improvement of quality of obstetric care. [ABSTRACT FROM AUTHOR]

Amazon River dolphins are an important flagship species in the Anavilhanas National Park, Brazil, where they interact with visitors. This study aimed to quantify and identify fungi isolated from dolphin skin and oral samples and their surrounding environment in this unique ecosystem. Samples were collected from three dolphins and water samples from Flutuante dos Botos and the Novo Airão city harbor. Fungi were isolated using culture media and identified through micromorphology assays and ITS region sequencing. Oral swab samples resulted in culture of Trichosporon montevideense and Exophiala dermatitidis. Skin samples from one dolphin revealed Toxicocladosporium irritans and Diaporthe lithocarpus. Water samples exhibited higher fungal counts and diversity, with Rhodotorula mucilaginosa, Exophiala dermatitidis, Penicillium citrinum, Fomitopsis meliae, and Nectria pseudotrichia identified at the collection site and Candida spencermartinsiae and Penicillium chermesinum at the city harbor. This study provides important insights into the fungal diversity associated with Amazon River dolphins and their environment, enhancing our understanding of the public health and ecological dynamics in the Anavilhanas National Park. [ABSTRACT FROM AUTHOR]

In the current global context of climate change and the increasing demand for sustainability, optimizing agricultural production is very important in order to meet the demands for food and to mitigate environmental impact. To achieve sustainable agricultural production, particularly in regions with tropical soil and climate conditions, is necessary to adopt conservation‐oriented techniques. This includes no‐tillage system, the use of soil‐cover crops, and the application of inoculants. The objective of this research was, at the end of the 22nd cropping season, to assess the influence of soil compaction in the production of green corn (Zea mays L.) in a long‐term field experiment. This study was conducted under different soil tillage systems in a Red‐Yellow Ultisol from the Coastal Tablelands of northeastern Brazil. Three soil tillage systems were applied: Conventional Tillage (CT), Minimum Tillage (MT), and No‐tillage (NT). These were combined with four previous crops: cowpea (Vigna unguiculata), crotalaria (Crotalaria juncacea), pigeon pea (Cajanus cajan), and millet (Pennisetum glaucum), as well as two levels of nitrogen fertilizer application: (1) 100% of the recommended N dose, and (2) 50% of the recommended N dose plus Azospirillum brasilense inoculant. The experimental design consisted of strip plots with subplots divided and randomized within each strip, with three replications. Soil compaction was assessed using parameters of soil density (SD) and soil mechanical resistance to penetration (MRP) in conjunction with moisture content (MC). The principal component analysis (PCA) highlighted that conservation‐oriented systems exhibited greater soil organic carbon (SOC) levels, leading to increased productivity of commercial green corn cobs. The synergistic effect of diversifying previous crops and adopting conservation tillage systems, especially in soils under long‐term tillage, resulted in heightened productivity of commercial green corn ears. [ABSTRACT FROM AUTHOR]

Background: Fat Free Mass (FFM) is an important and essential indicator in various sports populations, since greater muscle and bone mass generates greater strength, endurance and speed in athletes. Objective: The purpose of the study was to validate Body Surface Area (BSA) as an anthropometric indicator to estimate FFM in young basketball players. Methods: A descriptive cross-sectional study was carried out in 105 male basketball players of the Brazilian Basketball Confederation of Sao Paulo (Campinas), Brazil. The age range was 11 to 15 years. Weight and height were evaluated. BSA, body mass index (BMI) and maturity status (MS) were calculated. Total body scanning was performed by dual X-ray absorptiometry (DXA). The components were extracted: Fat mass (FM), Fat free mass (FFM), percentage of fat mass (%FM) and bone mass (BM). The data were analyzed using the correlation coefficient of concordance (CCC) in terms of precision and accuracy. Results: Three regression equations were generated: equation 1 had age and body weight as predictors [FFM= -30.059+(2.926*age)+(0.625*Weight)] (R2 = 92%, precision = 0.96 and accuracy = 0.99), equation 2 used age and BSA [FFM=-45.719+(1.934*age)+(39.388*BSA)] (R2 = 94%, precision = 0.97 and accuracy = 0.99) and equation 3 was based on APHV and BSA [FFM=-15.284+(1.765*APHV)+(37.610*(BSA)] (R2 = 94%, precision = 0.96 and accuracy = 0.99). Conclusions: The results suggest the use of anthropometric equation using decimal age and BSA to estimate FFM in young basketball players. This new method developed can be used to design, evaluate and control training programs and monitor the weight status of athletes. [ABSTRACT FROM AUTHOR]

Brazilian moist forests and savannas are some of the most species-rich biomes in the Neotropics. In the transition zones between these regions, ecotones often accumulate even higher taxonomic diversity. However, whether these ecotonal communities consist of overlapping species widespread from the neighbouring biomes or a specific set of locally adapted species still needs to be clarified. Regional differences in species richness may be influenced by factors such as species' environmental tolerances, life forms, or species' range sizes. To investigate the species richness found in ecotones, we used the 'milk-weed' family (Apocynaceae), which comprises both widespread and narrowly distributed trees, lianas, and shrubs, as a model to evaluate if (i) their observed richness in ecotones is promoted by widespread species or by locally adapted species; (ii) trees, lianas, and shrubs show different richness patterns in savannas, ecotones, and forests; and (iii) species found in ecotones have broader environmental tolerances than other species in the family. We used a taxonomically curated georeferenced dataset to compare the range sizes of 643 species of Apocynaceae from 73 genera listed for Brazil, comprising 298 species with a liana life form and 345 trees, herbs, or shrubs. We recorded 335 predominantly forest species, 56 savanna species, and 152 ecotone species, for which we quantified species richness, areas of occurrence, precipitation, and temperature ranges and tested for differences in range sizes and environmental tolerances between habits and ecoregions. Our results indicate that (i) Apocynaceae species occurring in ecotones have wider geographical ranges than species not occurring in ecotones; (ii) lianas showed higher area-weighted richness in ecotones than other life forms; and (iii) species found in ecotones had broader environmental tolerances than species restricted to moist forests or savannas. These results indicate that the species richness found in ecotones between savannas and moist forests in Brazil is not necessarily a consequence of higher endemism and local adaptation but may also be a result of overlapping ranges of widespread species typically associated with neighbouring biomes. Together, our findings add to our understanding of ecotones and biomes as continuous, gradual biogeographical transitions instead of sharply defined ecological units. [ABSTRACT FROM AUTHOR]

This article focuses on the circulation of a single artefact, the "Museu Escolar Brasileiro" (Brazilian School Museum) and its use in education through the pedagogical method of object lessons. Concentrating on the activities of particular individuals and enterprises (Menezes Vieira, Oliveira Lopes and Maison Deyrolle), within three geographical spaces (Brazil, Portugal and France), this article seeks to explore the relationship between the national and the international in educational proposals and initiatives that emerged at the end of the nineteenth century. The approach adopted also allows connections between the history of education and the history of science during this period to be pursued.

The oral cavity is the portal of entry for many microorganisms that affect swine, and the swine oral fluid has been used as a specimen for the diagnosis of several infectious diseases. The oral microbiota has been shown to play important roles in humans, such as protection against non-indigenous bacteria. In swine, studies that have investigated the microbial composition of the oral cavity of pigs are scarce. This study aimed to characterize the oral fluid microbiota of weaned pigs from five commercial farms in Brazil and compare it to their respective fecal and environmental microbiotas. Bacterial compositions were determined by 16S rRNA gene sequencing and analyzed in R Studio. Oral fluid samples were significantly less diverse (alpha diversity) than pen floor and fecal samples (P < 0.01). Alpha diversity changed among farms in oral fluid and pen floor samples, but no differences were observed in fecal samples. Permutational ANOVA revealed that beta diversity was significantly different among sample types (P = 0.001) and farms (P = 0.001), with separation of sample types (feces, pen floor, and oral fluid) on the principal coordinates analysis. Most counts obtained from oral fluid samples were classified as Firmicutes (80.4%) and Proteobacteria (7.7%). The genera Streptococcus, members of the Pasteurellaceae family, and Veillonella were differentially abundant in oral fluid samples when compared to fecal samples, in which Streptococcus was identified as a core genus that was strongly correlated (SparCC) with other taxa. Firmicutes and Bacteroidota were the most relatively abundant phyla identified in fecal and pen floor samples, and Prevotella_9 was the most classified genus. No differentially abundant taxa were identified when comparing fecal samples and pen floor samples. We concluded that under the conditions of our study, the oral fluid microbiota of weaned piglets is different (beta diversity) and less diverse (alpha diversity) than the fecal and environmental microbiotas. Several differentially abundant taxa were identified in the oral fluid samples, and some have been described as important colonizers of the oral cavity in human microbiome studies. Further understanding of the relationship between the oral fluid microbiota and swine is necessary and would create opportunities for the development of innovative solutions that target the microbiota to improve swine health and production. [ABSTRACT FROM AUTHOR]

Background: The prevalence of intestinal parasites is known to be high among Amerindian populations; further, there are serious problems in the healthcare of these populations in Brazil. The Maxakali, located in the northeastern region of Minas Gerais, Brazil, is an indigenous group that still preserves many of its cultural aspects. This study aimed to compare the positivity rate of schistosomiasis and soil-transmitted helminths in this ethnic group in epidemiological surveys conducted in 1972 and 2014. Methods: Stool parasitological examinations were performed by the Kato-Katz technique during both periods in this population. In 2014, the parasitological diagnosis was also realized with the TF-Test® technique. Results: In 1972, 270 inhabitants were examined. The positivity rates were 67.4% for Schistosoma mansoni, 72.9% for hookworms, 43.7% for Ascaris lumbricoides, and 23.7% for Trichuris trichiura. In 2014, 545 individuals were examined, and the positivity rates obtained were 45.7% for S. mansoni, 22.8% for hookworms, 0.6% for A. lumbricoides, and 2.8% for T. trichiura. Conclusions: The comparison of the parasitological surveys conducted in 1972 and 2014, indicates that the indigenous Maxakali remained neglected by the health and indigenous protection authorities during these four decades. The infection rate observed in 2014 for schistosomiasis and hookworm remains high, considering the current epidemiological view of these diseases in the Brazilian population. [ABSTRACT FROM AUTHOR]

Reservoir quality in carbonates is influenced by various factors such as the depositional environment, burial history and diagenesis processes. Understanding these geological heterogeneities is essential for successful petroleum exploration. This study characterizes Brazilian pre-salt reservoirs and aims to understand how their heterogeneity impacts reservoir quality. We analysed carbonate samples from the Barra Velha Formation (Santos Basin) through an integration of petrographical and core plug descriptions, petrographical facies characterization, porosity and permeability measurements, and image analysis to identify the principal controls on porosity and permeability, pore-size distribution, and groups with similar petrophysical properties using the hydraulic flow unit (HFU) concept. Five facies groups were recognized: Spherulitestone (F1); Shrubstone (F2); Intraclastic Grainstone (F3); Intraclastic Packstone, Spherulitestone with mud and Shrubstone with mud (F4); and Shrub–Spherulite Intercalations and Bioclastic Grainstone (F5). The analysis of porosity and permeability showed that their variations are associated with pore type and cementation rate. Greater contributions of inter-aggregate, interparticle and vugular porosity, combined with a reduced amount of cement, results in higher porosity and permeability but an increase in cement tends to reduce the porosity and permeability. Among the facies groups, F2 and F3 exhibited the best porosities and permeabilities, followed by F1, F4 and F5. From image analysis, small pores (1.5 × 10−5–0.01 mm2) are the most common in all rocks. However, these small pores contributed significantly to total porosity only in F4 and some samples of F3. For F2 and F3, the large pores (from 0.01 mm2 to a maximum of 19.62 mm2) are the main contributors, while F5 has a homogeneous contribution. Finally, the data were grouped into five HFUs: HFU1 and HFU2 represent the zones with the best reservoir quality, primarily composed of F2 and F3. [ABSTRACT FROM AUTHOR]

Copyright of Acupuncture in Medicine is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Simple Summary: Annually, various corn hybrids are introduced to the market for cultivation. Companies engaged in developing these technologies aim to enhance genetic traits, with a focus on creating productive hybrids capable of addressing the challenges of agriculture. The global corn market predominantly concerns livestock feed production, particularly for poultry farming, which seeks nutrient-rich raw materials with high digestibility for broilers. Nevertheless, when comparing the diverse transgenic technologies of corn, even when cultivated under the same conditions, significant differences were observed. Surprisingly, in the present study, the most productive corn transgenic technology in the field exhibited increased contamination by mycotoxins and a lower content of some important nutrients for poultry. This outcome highlights the critical need for a comprehensive assessment of the implications of transgenic technologies for nutritional composition and agricultural product safety, especially when intended for animal feed. Consequently, we concluded that the integration of nutritional considerations into the genetic improvement of transgenic corn, along with detailed information about resistance to Fusarium, holds great significance and may yield positive outcomes in the future. This approach ensures the production of nutritionally balanced, mycotoxin-safe, and economically viable livestock feed. Corn is one of the most produced cereals in the world and plays a major role in poultry nutrition. As there is limited scientific information regarding the impact of transgenic technology on the quality and nutrient composition of the grains, this study investigated the effect of three major transgenic corn varieties—VT PRO3®, PowerCore® ULTRA, and Agrisure® Viptera 3—on the field traits, nutrient composition, and mycotoxin contamination of corn grains cultivated in southern Brazil during three consecutive harvests. VT PRO3®, while demonstrating superior crop yield, showed susceptibility to mycotoxins, particularly fumonisins. In contrast, PowerCore® ULTRA, with the lowest yield, consistently exhibited lower levels of fumonisins. VT PRO3® had higher AMEn than the other varieties, while PowerCore® ULTRA had the highest total and digestible amino acid contents over the three years. The study's comprehensive analysis reveals the distinct impact of transgenic corn technologies on both productivity and nutritional levels. Balancing the crops yield, mycotoxin resistance, and nutritional content of corn is crucial to meet the demands of the poultry feed industry. Such insights are essential for decision-making, ensuring sustainability and efficiency in agricultural production as well as meeting the demands of the poultry industry. [ABSTRACT FROM AUTHOR]

The trade of wild animal parts as souvenirs, hereafter termed zoohandicrafts, has witnessed significant growth in Brazil due to increasing tourism and the associated demand for souvenirs. This study aimed to investigate the diversity of marine wildlife traded as zoohandicrafts along the Brazilian coast, identify the prevalent categories for these products, and assess the extent of this trade across the country. Sampling was conducted in 23 markets at tourist destinations, covering 11 states from the Northern, Northeastern, Southeastern, and Southern regions of Brazil, between 2017 and 2022. A total of 160 items or voucher specimens were examined, revealing the presence of 68 invertebrate species and two fishes. Statistical analysis indicated significant variations in the number of species across different categories of use and within the visited states and regions. Several species were found to serve multiple purposes. Whole mollusk shells constituted the most frequently traded item, with 58 identified species. Non-metric multidimensional scaling (NMDS) revealed two distinct groups—one including species with diverse uses in all regions of Brazil and the other encompassing species predominantly associated with decoration and religious purposes—particularly in the Northeastern and Southeastern regions of Brazil. An increasing diversity of species and a lower frequency of use were observed in the Southeastern region, relative to the Northeastern region. Approximately 20% of the species recorded are exclusively from the Indo- Pacific Ocean and are regarded as non-native to Brazil. Only 12 of the species were listed in the International Union for the Conservation of Nature (IUCN) Red List, and two are regulated by the Convention on International Trade in Endangered Species (CITES). This research sheds light on the status of the zoohandicraft trade in Brazil and highlights the lack of regulatory measures, the potential threats posed to biodiversity loss, and the economic importance of these species for people’s livelihoods. Further investigations are required to gain a comprehensive understanding of the actual social, economic, and ecological impacts of the trade in zoohandicrafts in Brazil and to devise strategies that promote both conservation and the socioeconomic wellbeing of all people involved in this commerce, from sourcing, production, distribution, and sale. [ABSTRACT FROM AUTHOR]

Cryptococcosis in HIV-negative patients can be an opportunistic or endemic disease. There are no published studies on the use of the finger-prick whole blood (point-of-care) cryptococcal antigen lateral flow assay (CrAg LFA) for diagnosing cryptococcosis in HIV-negative patients. We conducted a case series study of HIV-negative patients with cryptococcosis in two centers in São Paulo, Brazil. The objectives were to identify the sensitivity of a finger-prick whole blood CrAg LFA and to describe the main characteristics of this population. We identified 30 HIV-negative patients with cryptococcosis [19 (63%), male; median age, 47 years]. Ten (33%) patients were immunosuppressed, ten (33%) had other comorbidities, and ten (33%) were apparently immunocompetent and without comorbidities. The distribution of the sites of cryptococcosis was as follows: the central nervous system, 90% (n = 27); pulmonary, 43% (n = 13); and other extrapulmonary sites, 40% (n = 12). The sensitivity of the finger-prick whole blood CrAg LFA for the diagnosis of cryptococcosis was 97% (29/30). Among 26 participants with cryptococcal meningitis, the sensitivity of testing cerebrospinal fluid was as follows: CrAg latex agglutination, 77% (20/26); CrAg LFA, 96% (25/26); and culture, 81% (21/26). Culture speciation identified Cryptococcus gattii in 16 (62%) cases, and all had a positive finger-prick whole blood CrAg LFA. This test presented high sensitivity to the diagnosis of cryptococcosis in HIV-negative patients, including those caused by C. gattii. [ABSTRACT FROM AUTHOR]

Geonoma maxima (Poit.) Kunth is an example of a species complex, among many others restricted to Neotropical rain forests, which contribute to their high species diversity. Using environmental, morphological, karyological, and molecular data, we aim to test the taxonomic circumscription of 3 of the 11 G. maxima subspecies defined in the latest taxonomic treatment. We evaluated 217 samples of G. maxima complex from Ducke Reserve in the state of Amazonas, Brazil. Environmental preferences were significant at the 0.1% level. Subspecies maxima occurred in the slope, subsp. chelidonura in the floodplain, and subsp. spixiana in the plateau. Leaf morphology and height were different for each subspecies, but not leaf anatomy. The karyotypes of subspp. chelidonura and maxima were symmetrical with 2n = 28 chromosomes, 16 metacentric and 12 submetacentric. Molecular analysis revealed two groups, one comprised subspp. maxima and chelidonura, and the other formed exclusively by subsp. spixiana. At Ducke Reserve, it is clear that the three subspecies are easily recognizable morphologically and ecologically, and it is likely that they do not interbreed locally. However, if these subspecies are analyzed on a larger geographic scale, it may not be possible to separate them. [ABSTRACT FROM AUTHOR]

Rabies transmitted by wildlife is the main source of human rabies mortality in Latin America and considered an emerging disease. The common marmoset Callithrix jacchus of Brazil is the only known primate reservoir of rabies worldwide. We tested whether alive free-ranging C. jacchus were exposed to rabies in four northeast states that have previously reported rabies-positive dead C. jacchus (Pernambuco and Bahia) or not (Paraíba and Rio Grande do Norte). Our results show no evidence of rabies antibodies or infection in the sampled C. jacchus, suggesting that apparently healthy marmosets are not widely exposed to rabies over their natural range. [ABSTRACT FROM AUTHOR]

The production and export of sugar defined the colonial history of Brazil. It was here that the first modern slave based plantation system was created in America. Up through the end of the 17th century it was the dominant Atlantic producer of sugar. Although production continued to grow it was replaced in world markets in the 18th century by West Indian growers and was late to modernize in the 19th and early 20th century. Yet today it is once again the world's dominant producer of sugar and the second largest producer of ethanol. How and why these changes occurred is the theme of this essay in which we explore the rise of the modern sugar and ethanol industries in Brazil. [ABSTRACT FROM AUTHOR]

Background: Radiology is a useful tool for diagnosis and intervention in medical practice, and all the components within the teaching-learning process of this subject during undergraduate studies influence successful knowledge application. Objective: This study aimed to describe the level of knowledge in radiology of students in the last two years of medical school and curricular characteristics of their courses in seven Latin American countries. Methods: A multicenter cross-sectional study was carried out on medical students of 7 Latin American countries (Bolivia, Brazil, Colombia, Ecuador, Mexico, Paraguay, and Peru) in their final two years of medical school, using an online questionnaire validated by experts and adapted for each country that assessed knowledge and curricular characteristics in radiology subject. Scores were assigned according to the number of correct answers for the knowledge test. The T-test, and regression analysis with one-way ANOVA were used to search for relationships between the level of knowledge and other variables. Results: A total of 1514 medical students participated in this study. All countries had similar participation (n > 200); most participants were women 57.8%. The country with the highest knowledge score was Brazil. Male, sixth year (internship) and from public universities students had higher knowledge score (n < 0.05). Participants, who considered radiology more important, and who reported higher compliance with teaching staff with the proposed syllabus, and programmed classes, obtained better scores (n < 0.05). Conclusions: Latin American medical students included in this study have a regular overall level of knowledge of Radiology, apparently influenced by curricular differences such as class and academic program compliance. Efforts to better understand and improve academic training are indispensable. Limitations: The study was subject to selection bias determined by non-probability convenience sampling. The questionnaire assessed only theoretical knowledge and the evaluation system was designed by the investigators. [ABSTRACT FROM AUTHOR]

The growing proximity of wildlife to large urban niches arouses greater interest in understanding wild reservoirs in the epidemiology of diseases of importance to animal and human health. The aim of the present study was to investigate the presence of piroplasmids in opossums rescued from the metropolitan region of Rio de Janeiro state, Brazil. Blood and bone marrow samples were collected from 15 Didelphis aurita and subjected to DNA extraction and PCR using primers for the 18S rRNA, cox1, cox3, and hsp70 genes of piroplasmids. Clinical and hematological evaluation of the animals was also performed. Five (33.3%) of the 15 opossums tested positive for piroplasms in the nested PCR based on the 18S rRNA, and in two animals, it was possible to observe intra-erythrocytic structures compatible with merozoites. One of the positive animals showed clinical signs of infection such as jaundice, fever, and apathy. Anemia, low level of plasma protein, leukocytosis, and regenerative erythrocyte signs were observed in positive animals. Phylogenetic analysis based on both 18S rRNA and cox-3 genes demonstrated that the piroplasmids detected in D. aurita formed a unique sub-clade, albeit related to piroplasmids previously detected in Didelphis albiventris and associated ticks from Brazil. This study proposes the novel Piroplasmida Clade, namely "South American Marsupialia Group," and reinforces the need for new clinical-epidemiological surveys to understand the dynamics of these infections in didelphids in Brazil. [ABSTRACT FROM AUTHOR]

The historical meeting between originally American people, European colonizers, and slaved peoples from Africa in the biome Pampa in South Brazil and Uruguay involved a cultural syncretism and a great genetic diversity of landraces of cultivated species. Genetic richness evolved by selection and cultural processes in response to different environments, cultural backgrounds, and needs. This review summarized the knowledge on vegetable and maize landraces in South Brazilian and Uruguayan Pampa biome, to design a strategy towards the rediscovery, conservation, and sustainable use. Landraces diversity maintained in situ and ex situ is described, specific case studies are presented, and the main problems and tools towards landraces re-valorization are discussed. We show that traditional family farming systems maintain diverse vegetable species, mainly squashes (Cucurbita spp.), sweet potato (Ipomoea batatas), beans (Phaseolus spp.), onion (Allium cepa), peppers (Capsicum spp.), tomato (Solanum lycopersicum), next to leafy vegetables and maize, among others. We propose the priority of systematic surveys as a basis for monitoring genetic erosion, increasing complementariness between in situ and ex situ conservation, and implementing sustainable conservation and utilization. The case studies highlight genetic diversity within each cultivated species, with different crop physiological responses; disease resistances, different quality traits and associated uses, from animal feeding in maize to a range of culinary uses linked to traditional culture in maize and vegetable species, and ornamental uses of specific Capsicum and Cucurbita. Some landraces were the basis for breeding, where improved cultivars allowed the competitiveness of landrace germplasm in the markets. Renewed industrialized products allowed the competitive and sustainable use of Capsicum landraces in Brazilian farmers communities. Strategies towards in situ conservation improvements and valorization are discussed; emphasizing the role played by agroecology, community seed banks and custodian farmers, participatory plant breeding, promotion of landraces specialties among consumers, and the need of research and capacity building, among others. Farmers' participation in the decisions is a key factor, along with the academia and the public sector. Landraces and associated knowledge are treasures to be used to benefit from farmers to consumers, directing the course of agriculture towards sustainable directions. [ABSTRACT FROM AUTHOR]

Objective: a) to verify whether body composition and physical fitness should be analyzed by chronological age and/or maturity stage in young Brazilian soccer players and b) to propose reference values for the evaluation of body composition and physical fitness by maturity stage in elite soccer players. Methods: A descriptive-correlational study was carried out in 206 young Brazilian soccer players (11-16 years old). The sample selection was non-probabilistic by convenience. Weight and standing height were evaluated. Body composition (BC) was assessed by dual X-ray absorptiometry (DXA). BC indicators [(percent fat (%F), Fat-free mass (FFM), Fat mass (FM) and Bone mass (BM)] were extracted. For physical fitness (PF), we applied the Flexibility (cm) sit and reach tests, explosive strength tests [Counter Movement Jump CMJ (cm) and horizontal jump HJ (cm)], speed [Speed 10, 20, 30 and 40m (seconds)] and Yo-Yo endurance level I test. Percentiles were constructed for BC and PF using the LMS method [L (Lambda; skewness), M (Mu; median) and S (Sigma; coefficient of variation)]. Results: The explanatory power between chronological age (CA) with BC was: FM (R2 = 0.03%), FFM (R2 = 0.66%) and BM (R2 = 0.62%), while between maturity status (MS) with BC were: FM (R2 = 0.04%), FFM (R2 = 0.71%) and BM (R2 = 0.66). The explanatory power between the CA with the physical fitness tests ranged from: (R2 = 0.22-0.62%). While between MS with physical fitness the values ranged from: (R2 = 0.23-0.64%). Percentiles per MS (P3, P5, P10, P15, P25, P50, P75, P85, P90, P95 and P97) were proposed for both BC and PF. Conclusion: The results of the study have shown that the evaluation of BC and PF of young soccer players should be performed by controlling for MS rather than for CA. The inclusion of a non-invasive method to control MS by means of percentiles during puberty may contribute to the development of retention and exclusion of young soccer players, thus, they may have a better chance of achieving sporting success. [ABSTRACT FROM AUTHOR]

Simple Summary: Vaccination can prevent infection by opportunistic bacteria that affect fish. We have developed and analyzed a bivalent vaccine against two of the main pathogens that affect fish. We found that the vaccine was safe and effective in laboratory tests and in large-scale tests, with better survival and feed conversion in immunized animals. These results indicate the need for field tests to confirm real protection. This developed vaccine could allow fish farmers greater protection for commercial fish production. One of the main factors limiting tilapia's production is the occurrence of infections caused by Aeromonas and Streptococcus species. This work intended to evaluate a bivalent vaccine against A. hydrophila and S. agalactiae by intraperitoneal (i.p) administration in Nile tilapia (Oreochromis niloticus) in Brazil. The study was carried out in two phases: one in the laboratory, on a small scale, and from the results obtained, the study was expanded to a large scale in a production system in cages. The vaccine proved to be safe and effective in laboratory tests, with a vaccine efficacy (VE) of 93.66%. However, in large-scale tests with 12,000 tilapias, the VE was 59.14%, with a better food conversion ratio (1.54 kg) in the vaccinated group compared to the control group (1.27 kg). These results corroborate the efficiency of this tested vaccine; however, they indicate the need for field tests to attest to real protection. [ABSTRACT FROM AUTHOR]

Lithology plays a fundamental role in rock weathering and erosion, and in landscape evolution. When weathering‐ and erosion‐prone lithologies are protected from erosion by more resilient rock types (e.g., quartzites and banded iron formations) unusual weathering products result. At the Southern Espinhaço Range, Minas Gerais, Brazil, bauxitic weathering profiles are found in a unique geomorphological–lithological–climatic setting. Resistant quartzites acted as a barrier against erosion of interbedded hematite‐phyllite lenses, channelling solution flows and facilitating the formation of deep weathering profiles. The long‐term exposure of the hematite‐phyllites under alternating wet and dry tropical climates favoured widespread bauxitization. Here we investigate the geochemical, mineralogical, geochronological and micromorphological signatures of scaffolded bauxites in order to reconstruct their evolutionary history. Our data suggest that recurrent aluminium and iron mobilization within the profiles were mainly driven by mineral dissolution‐reprecipitation mediated by bioturbation and the influx of vegetation‐derived organic species. (U–Th)/He geochronology of Al‐goethite reveals that bauxitization started at least since the Lower Miocene, with important intensification of weathering in the Upper Miocene and Lower Pleistocene. The adjacent resilient quartzites acted as scaffolds for bauxitization and supported the preservation of more erodible weathering profiles developed over phyllites. Surface waters that could not infiltrate into the impermeable adjacent quartzites preferentially infiltrated into the more weathereable phyllites, enhancing their porosity and permeability, further enhancing weathering. The evolutionary history of Southern Espinhaço Range bauxites suggests a new model of bauxitization in ancient land surfaces evolution underlain by quartzites, where erosion‐prone lithologies are scaffolded by resilient quartzites and survive long‐term weathering with minimum erosion, producing bauxites. [ABSTRACT FROM AUTHOR]

Ecotourism is a strategy for biodiversity conservation, but it involves possible negative effects on animal health and welfare. Large predators such as crocodilians are one of the great public attractions sought after for tourist interactions. Interactions with wild animals and humans can hyperstimulate the hypothalamic‐pituitary‐adrenal axis in the short term, in the case of crocodilians showing an increased corticosterone level, which is indicative of physiological stress. Between September and December 2019, we simulated interactions between tourists and Amazonian crocodilians at Anavilhanas National Park in Central Amazonia, Brazil to evaluate the effects of handling and use of photographic flashes on black caiman (Melanosuchus niger) and spectacled caiman (Caiman crocodilus) on circulating corticosterone and lactate. Corticosterone levels increased 1.7‐fold during handling and 2.7‐fold when exposed to photographic flashes in black caiman but not in spectacled caiman. Increased corticosterone concentrations in black caiman were characterized by an increase caused by handling and were more intense after flashes than in controls, but the combination of handling and flash had no effect. During handling in simulated tourist interactions, anaerobic respiration increased lactate in black caiman but not in spectacled caiman. The effect of simulated tourist interactions with Amazonian crocodilians was dependent on the handling and especially on flash use in black caiman. The results can assist management, conservation programs, and public policies, especially in programs based on tourism interaction with Amazonian crocodilians. [ABSTRACT FROM AUTHOR]

The porous systems of carbonate reservoirs show a great diversity of pore types and high heterogeneity that can reflect the interplay of several elements including physical, chemical, and biological depositional processes, intense diagenesis, fracturing, and hydrothermal alterations. All these factors combine in the Aptian Barra Velha Formation carbonates from Santos Basin, SE offshore Brazil, which comprises the most prolific hydrocarbon reservoirs from Brazil. The geological complexity of this formation has represented a major challenge for oil forecast, recovery and production. The absence of outcrops, proper analogs and the limited access to core samples of this deep formation adds to the challenges involved in the geological and petrophysical characterization of such reservoirs. In this context, X-ray computed tomography (CT) can become a key technique applied for non-destructive quantitative analyses and 3D visualization of different rock structures. The present article reports the results obtained from X-ray CT images applying digital rock analysis to characterize the complex pore networks and mineral phases of the Barra Velha Formation reservoir. Multi-resolution CT-scan petrophysics was combined with detailed petrography and petrology, aiming to understand the geological factors controlling porosity distribution. Mineral segmentation was split into three mineral phases: carbonate, undefined (microporosity and diagenetic material) and dense minerals. The high percentage of undefined phase was commonly associated with intense dolomitic cementation and related to low permeabilities. Shrubstone and Intraclastic rudstone lithologies showed the best reservoir properties, mainly when the dominant growth framework and interparticle porosity, was associated with dissolution, enhancing the pore connectivity. Pore network analysis revealed the tendency of larger pores to be associated with higher coordination numbers, presenting greater pore connectivity. This study aims to contribute to future work on Brazilian pre-salt carbonates' pore type and multi-scale characterization, providing new insights into the characteristics and factors related to the samples' connectivity. Article highlights: The use of X-ray CT image processing approach allowed non-destructively to analyze rock samples, and to obtain detailed information about their internal structure. Image analysis using X-ray CT has enabled a more detailed characterization of lacustrine pre-salt carbonate rock samples by segmenting the mineral phases and calculating porosity. The DRA approach was proposed to obtain a digital rock model based on different pore-scale information, including medial CT and high-resolution CT scans. [ABSTRACT FROM AUTHOR]

This study aimed to investigate the impact of as-received biomass fly ashes (BFA) and green liquor dregs obtained from a pulp and paper plant in Brazil as substitutes for metakaolin in geopolymeric formulations. The properties of this type of waste material vary widely between different industrial plants. This study refrains from subjecting the waste materials to any form of pretreatment, taking into account their organic matter and particle size heterogeneity, requiring extensive characterization to evaluate their influence on the compressive strength, apparent open porosity, and water absorption of the geopolymeric samples. The objective was to assess their potential for upcycling purposes as an alternative to energy-intensive materials, such as ordinary Portland cement (OPC) and advanced ceramics. This potential arises from the ability of alkali-activated materials (AAM) to undergo curing at ambient temperatures, coupled with the possibility of compositions primarily derived from waste materials. To improve the sustainability of the products, the amorphous content of the raw material, which is more reactive than crystalline phases, was quantified and used as the base for mixture ratios. This approach aimed to reduce the requirement for alkaline activators, which have significant environmental impacts, while also increasing the waste content in the formulation. The incorporation of waste materials into the geopolymer matrix generally led to a reduction in the compressive strength compared to the benchmark metakaolin sample (19.4 MPa) but did not present a trend. The dregs led to values of 4.1 MPa at 25 wt% and 7.1 MPa at 50 wt%, a behavior that is somewhat counterintuitive, and BFA at 10 wt% presented 5.7 MPa. Nevertheless, the apparent open porosity remained at high levels for all the samples, close to 50%, and the compressive strength of most of them was over the values obtained for the metakaolin-only samples with mixture ratios calculated from the total composition instead of the amorphous composition. The decrease in strength and the increase in porosity were attributed to the specific characteristics of the waste materials, such as their high crystallinity, presence of organic matter, heterogeneous particle composition, and size. Overall, this study provides insight into the variations in geopolymerization based on the bulk and amorphous content of the aluminosilicate sources and how the characteristics of the waste materials influence the geopolymer matrix. It also highlights how calculating mixture ratios based on the amorphous composition improves the possibility of waste valorization through alkali activation. Additionally, it suggests that BFA and dregs might be effectively utilized in applications other than OPC substitution, such as adsorption, filtration, and catalysis. [ABSTRACT FROM AUTHOR]

Introduction: Brazilian nursing seems to have reached important levels of learning during the pandemic, not only because of the need to control the circulation of the new coronavirus and care for the sick. Objective: To know the learning generated from the COVID-19 pandemic among nurses. Methods: exploratory and qualitative study, carried out in August and September 2021, with tertiary health care nurses who were on the front line during the pandemic, in the State of Mato Grosso, Brazil. Individual interviews were carried out, based on guiding questions. For data analysis, the collective subject discourse was used. Results: As learnings generated, the participants pointed out professional aspects (theoretical/practical), as well as personal aspects (reflection of the value of the human being, family and professional fulfillment). Conclusion: The learning provided by the pandemic, while contributing to the perception that in the face of insecurity and uncertainty it is possible to learn and develop, highlights the strength of nurses, who were initially weakened during the pandemic, but which potentiated the sensitivity to new discoveries, confrontations and strengthening of their individual and collective resources. [ABSTRACT FROM AUTHOR]

Assessing the phosphorus (P) balance in agricultural soils is crucial for optimizing its use and reducing contamination risks. The objective of this study was to evaluate the impact of different animal wastes on the distribution of P in soil profiles subjected to 12 years of successive applications of animal wastes and mineral phosphate fertilizer, within a crop rotation system under no-till system. The study was conducted from 2004 to 2016 in the southern region of Brazil. The treatments were the applications of pig slurry (PS), cattle slurry (CS), pig deep-litter (PD), mineral fertilizer (MF), and a control treatment without application. The highest accumulation of P and its movement was observed in the 0–40 cm layer, in the soil submitted to applications of all P sources. The inputs of P via MF, CS, PS, and PD promoted the accumulation of 18, 42, 48, and 100 kg P ha−1 year−1. The P mass balance showed that between 77 and 98% of the P added by animal manure and MF was accounted for in grain exports (17–34%), soil storage (41–72%), and post-harvest residues (<1%), with the remaining 2–33%, unaccounted for, which was attributed, especially, to P transfer at the soil surface. [ABSTRACT FROM AUTHOR]

Erythrina L. is a genus that comprises ca. 120 to 130 species distributed throughout the tropics and subtropics of the world. Linnaeus established the genus in Genera Plantarum (1737) and the first binomial name given to a Brazilian Erythrina was E. crista-galli L., described by himself in Mantissa Plantarum (1767). Vellozo proposed in Florae Fluminensis (1790-1881) the first treatment of the genus in Brazil, where he treated three species from the states of Rio de Janeiro and São Paulo. Martins and Tozzi proposed the most recent treatment in 2018, where the authors recognized 11 valid names and presented three new synonyms. Despite extensive efforts already made in the genus, previous works did not treat all names related to the valid ones for Brazilian Erythrina. The present work is the most comprehensive and up-to-date nomenclatural treatment for the genus in Brazil, covering all 84 related names found on digital nomenclatural databases. Here we analyze 64 protologues, update typification statuses, propose five new synonyms, 13 new lectotypes (11 first-step, two second-step) and one neotype, linking all protologues and type specimens with their corresponding available digital sources, and make additional notes on etymology and vernacular names. [ABSTRACT FROM AUTHOR]

The Prisma Jurídico Magazine, January to June 2024 edition, presents eleven articles that address various topics related to law. The magazine aims to be a channel for scientific-academic production, with contributions from national and foreign authors, adopting the double-blind peer review method. In addition, the publication is concerned with endogeneity and guarantees exogeneity, promoting the exchange of information among Higher Education Institutions. The first article deals with the importance of ecofeminism for sustainable development and the applicable Brazilian legislation to the movement. Other topics covered include the acquisition of land by foreigners in Brazil, the irrationality of laws and mediation, universal basic income and the sustainable development goals, among others. The magazine concludes the edition by thanking the editing team and wishing readers an excellent reading experience. [Extracted from the article]

Precise knowledge of the spatial distribution patterns of non-matrix porosity zones and the establishment of the geological factors controlling their evolution are crucial for building more accurate carbonate reservoir models and improving hydrocarbon production. The occurrence of intervals affected by significant carbonate dissolution may result in drilling fluid loss and time-consuming drawbacks during well construction. Vug or cave-rich reservoirs may exhibit excess permeability and extremely high initial flow rates. Similar situations have been reported in exploration activities in the Brazilian pre-salt plays, where evidence of dissolution and other burial diagenetic processes, such as severe silicification and dolomitization, are common. In this study, we investigate evidence of major post-depositional changes in the lacustrine carbonate reservoirs of the Barra Velha Formation, which comprises the most prolific hydrocarbon play in Brazil. Using a comprehensive database consisting of both core samples and well-log data from a vertical well in the Santos Basin, we have characterized, at multiple scales, reservoir zones affected by silicification and carbonate dissolution. In addition, we have performed a petrophysical evaluation of the reservoir to understand the impact of such processes on porosity and permeability development. The results suggested an intimate relationship between silicification and dissolution processes, which can be associated with late fluid percolation under a deep burial flow regime. The occurrence of silicified and vuggy beds, associated with specific zones and lithofacies, indicates an important degree of stratigraphic control on fluid percolation and lateral migration. Furthermore, the presence of fractures at discrete stratigraphic levels has preferentially influenced the development of high-permeability zones, including metric-scale fracture-related conduits. This study contributes to the general knowledge of carbonate reservoirs affected by silicification and dissolution while providing support for the recognition of such processes in partially- or non-cored wells. [ABSTRACT FROM AUTHOR]

It has historically been frequent among geotechnical practitioners, that the stability analysis of the slopes of an open pit is performed using a two dimensional section representing the highest and steepest walls within a certain geological setting. However, the literature shows that to predict rupture events in an open pit, a three-dimensional analysis would better represent the actual conditions, as the spatial distribution of the lithology and the structural features play an important role when defining the stability of the slopes. This paper presents the case study of an open pit located in Brazil, which experienced instabilities between the years 2001 and 2019. An evaluation of the behavior of the open pit was performed by calibrating the strength parameters to represent the best documented rupture events. The three-dimensional model was made using the finite difference method. The results show that there is a good correlation between the results of the model and the reports of past instabilities. Finally, recommendations are presented for the inter-ramp angles for each lithology based on the calibrated stability analysis performed. This work seeks to contribute to the knowledge in evaluation techniques for the three-dimensional behavior of open pits. [ABSTRACT FROM AUTHOR]

Copyright of Fisioterapia Brasil is the property of Atlantica Editora and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Simple Summary: Our findings provide observational evidence supporting oral corticosteroids therapy as maintenance therapy for HTLV-1-associated myelopathy (HAM). The daily use of oral, low-dose prednisone seems to be useful in some subsets of HAM patients and needs to be evaluated in randomized controlled trials. Background: During the development of human T-cell lymphotropic virus (HTLV-1)-associated myelopathy (HAM), the inflammatory phenomenon is very prominent and is a major factor in the outcome of the disease. The use of corticosteroids can modify their natural history, and in this study, we evaluated the effectiveness of using daily low-dose prednisone. Methods: This was a cross-sectional study using data collected by physicians monitoring patients with HAM at the Institute of Infectious Diseases "Emilio Ribas", the main referral center for patients with infectious diseases in São Paulo, Brazil. The objective was to determine if daily low-dose oral prednisone would be able to stabilize the progression of HAM. The outcome measure was a change in the Osame Motor Disability Score (OMDS). Results: Fifty-four patients used treatment with oral prednisone, 5 milligrams daily. Nine cases were excluded from the study because they did not have at least two rating scales within a minimum interval of one year, and six were excluded for being co-infected with HIV and/or HCV. Thirty-nine patients met this criterion and were included for analysis. The majority were women (71.8%), the mean age was 56.51 years old (SD ± 9.74), and the median time of use of prednisone was 16 months. Thirty-two patients (82.05%) maintained the same OMDS, 5/39 (12.82%) had clinical worsening, and 2/39 (5.13%) improved. Conclusions: There was a trend toward clinical stability with the use of oral corticosteroids. However, randomized controlled trials are necessary to evaluate the use in clinical practices in all stages of HAM. [ABSTRACT FROM AUTHOR]

Riparian permanent protection areas (APP) are important for the protection of water resources. However, there are controversies concerning the delimitation and uses of spaces whose boundaries have been reconfigured over time. The evolution of laws and regulations related to riparian APPs were therefore analysed as well as their impacts on the uses of the river plains of the Santa Cruz River (Sertões de Crateús, Ceará/Brazil) between 1985 to 2019. A bibliographic and cartographic survey was thus carried out, satellite images were analyzed and field work was carried out. As a result, a tendency to reduce APPs and their protection was noted; the second Florest Code created and delimited the riparian APPs in Brazil; the plains and their APPs are occupied and later deteriorate due to farming and illegal mineral extraction. [ABSTRACT FROM AUTHOR]

Introduction: The normal intravenous human immunoglobulin is a sterile liquid or lyophilized preparation, with immunoglobulins, especially the immunoglobulin G (IgG). The National Institute for Quality Control in Health (NIQCH) performs analysis of biological products before being distributed to the population. The batches are subjected to physicochemical and biosafety assays. The rabbit pyrogen test (RPT) is a biosafety assay performed to check the contamination by agents that cause fever in the patient and, in cases of high concentration, can lead to death. Aim: To compare the results of RPT and bacterial endotoxins assays of ten samples. Methods: In RPT, both the product is injected into the rabbit's marginal ear vein and the individual body temperature variations of the animals are evaluated. The bacterial endotoxin assay uses the kinetic chromogenic method, according to the Brazilian Pharmacopoeia and the international compendiums. Results: The tests of were plotted in a table for comparison. The tests coincided in 9 samples, except for a sample that presented bacterial endotoxin pyrogenicity. Conclusion: Bacterial endotoxin assay must be considered as an alternative method for animal tests. [ABSTRACT FROM AUTHOR]

Envenomation by venomous fish, although not always fatal, is capable of causing damage to homeostasis by activating the inflammatory process, with the formation of edema, excruciating pain, necrosis that is difficult to heal, as well as hemodynamic and cardiorespiratory changes. Despite the wide variety of pharmacological treatments used to manage acute symptoms, none are effective in controlling envenomation. Knowing the essential role of neutralizing polyclonal antibodies in the treatment of envenoming for other species, such as snakes, this work aimed to produce a polyclonal antiserum in mice and test its ability to neutralize the main toxic effects induced by the venoms of the main venomous Brazilian fish. We found that the antiserum recognizes the main toxins present in the different venoms of Thalassophryne nattereri, Scorpaena plumieri, Potamotrygon gr. Orbignyi, and Cathorops spixii and was effective in pre-incubation trials. In an independent test, the antiserum applied immediately to the topical application of T. nattereri, P. gr orbygnyi, and C. spixii venoms completely abolished the toxic effects on the microcirculation, preventing alterations such as arteriolar contraction, slowing of blood flow in postcapillary venules, venular stasis, myofibrillar hypercontraction, and increased leukocyte rolling and adherence. The edematogenic and nociceptive activities induced by these venoms were also neutralized by the immediate application of the antiserum. Importantly, the antiserum prevented the acute inflammatory response in the lungs induced by the S. plumieri venom. The success of antiserum containing neutralizing polyclonal antibodies in controlling the toxic effects induced by different venoms offers a new strategy for the treatment of fish envenomation in Brazil. [ABSTRACT FROM AUTHOR]

Interpreting the ages of supergene mineralogical phases in laterite is complex because they consist of polycrystalline mixtures of different phases at the microscopic scale that could be crystalized at different epochs. Among the geochronometers, the (U-Th)/He method on hematite and goethite is more often used, but ages can be difficult to interpret due to phases mixing. To resolve this issue, this study proposes a methodology for performing detailed mineralogical analysis of hematite and goethite single grains prior to their dating using the (U-Th)/He method. Strictly non-destructive mineralogy of single grains is not achievable by classical tools, such as conventional powder XRD (X-ray diffraction; requiring at least some milligrams of powder) or SEM (scanning electron microscopy; that can contaminate the grain by coating or fixing). Therefore, we performed X-ray diffraction patterns of single grains using high-flux X-ray beams from both a rotating anode (XRD_rotat) laboratory diffractometer and a synchrotron beamline (XRD_synch) and compared the results in order to design a method based on XRD_rotat only. For this purpose, two samples from the pisolitic facies of a Brazilian ferruginous duricrust (Alto Paranaíba region, Minas Gerais State, Brazil) were chosen because they presented a usual heterogeneity. Rietveld refinements of the XRD patterns obtained from both XRD_rotat and XRD_synch yielded similar results for the weight percentage ratio of the main phases and mean coherent domain sizes and less similar results for Al substitution rates, thus validating the XRD_rotat approach. No beam damage was observed when increasing X-ray exposure time, neither on XRD patterns nor on (U-Th)/He ages. Hence, sub-millimeter, undisturbed grains can be used to analyze the mineralogy of ferruginous duricrusts by XRD_rotat with a short exposure, and the same grains can subsequently be dated by (U-Th)/He geochronology analysis. The (U-Th)/He dating of pisolitic core and cortex grains also provided meaningful ages: they revealed two evolution phases of the ferruginous duricrust, which occurred at or before the Oligocene for the pisolitic core and middle Miocene for the pisolitic cortex, agreeing with the previous model for the development of pisolites. The mineralogy of single grains selected for dating is helpful for discussing the crystallization ages, and the high-flux XRD approach may be applied to other supergene mineral parageneses used for absolute dating. [ABSTRACT FROM AUTHOR]

The detection of Giardia duodenalis and Cryptosporidium spp. was performed, along with the identification of the ciliated protozoa biodiversity, to evaluate the correlation between these protozoa in freshwater quality monitoring. Water and sediment samples from two sites in the Atibaia River (Campinas, São Paulo, Brazil) were collected monthly for 2 years (n = 96). Pathogenic protozoa in water and sediment were detected by using immunomagnetic separation, followed by visualization by immunofluorescence assay (IFA). All positive aliquots in IFA were subjected to DNA extraction and subsequently nested PCR. Qualitative (in vivo observation and silver impregnation) and quantitative (in vivo enumeration) analyses were performed for the ciliated protozoa. Giardia cysts were detected in 62.5% of the surface water samples and Cryptosporidium spp. in 25.0%. In the sediment, cysts were detected in 35.4% samples and oocysts in 16.6%. A total of 57 samples positive for Giardia cysts were subjected to sequencing, 40 of which were harboring G. duodenalis (24 were characterized as sub-assemblage AII). For ciliated protozoa, 73 taxa belonging to 53 genera were identified over the period of the study. These results revealed a high degree of contamination by waterborne protozoa in the main water source which supplies drinking water for more than one million people in Campinas (São Paulo), highlighting the need for continuous monitoring of this catchment site. In addition, the present study provides important data regarding the sources of the water body degradation, i.e., fecal contamination of human origin, in addition to the survey of the ciliated protozoa. [ABSTRACT FROM AUTHOR]

Purpose: This research aims to evaluate the factors that influence logistics outsourcing, including the impact of logistics outsourcing on measuring companies' logistics performance. This research provides interactions among the various factors (constructs) such as "financial", "collaboration and process characteristics", "external influencer", and "logistics performance". Design/methodology/approach: To investigate the interaction between the constructs, structural equation modelling is proposed to understand what the relevant criteria are while outsourcing logistics. Data were acquired from surveys conducted with 129 managers from Brazilian companies in the industry sector. Findings: The factor "collaboration and process characteristics" is what most influences the "logistics performance" of companies, highlighting the importance of managing contractors; and the "financial" factor also contributes to the logistic outsourcing decision. Research limitations/implications: Some limitations of this study need to be clarified. First, the model could test the moderate and mediate aspects by using variables inspired on RBV and TCE. Second, the sample is relatively small and restricted to the Brazilian industries' case, although the results may be useful for other countries in the world. Third, the responses represent viewpoints of the people who work in the companies. To address this issue, the authors asked respondents to fill out the questionnaire from the perspective of the organisation. Practical implications: Most 3PL come from developed countries and find different requirements in Brazil. Then, this new knowledge may help 3L providers better understand the needs of the local or foreign companies that operate in the local market. The measurement model may also help to construct a new organisational process, as it sheds light on the main elements necessary for gathering logistics performance outcomes. Originality/value: To the best of the authors' knowledge, the literature lacks studies on the interaction among these logistics outsourcing constructs, mainly in emerging markets where significant growth opportunities have led to logistics activities being outsourced. The literature that examines the impact of these constructs on logistics performance is also limited. Therefore, this research contributes to providing a model that measures these impacts according to the company's point of view. [ABSTRACT FROM AUTHOR]

In Brazil, there have been some initiatives to improve the development of Ministry of Health clinical protocols and therapeutic guidelines (PCDTs in Portuguese, and clinical practice guidelines—CPGs, in English) and their implementation so that best practices can be disseminated and adopted at multiple levels of health systems. One of the initiatives was to conduct a pilot project to improve the format of these CPGs. The objective of this article is to present the processes and results of the pilot project, including the development of a new standardized format for CPGs to promote national dissemination and uptake. The pilot project was designed in three phases: identification and selection of strategies to effectively implement clinical practice guidelines, definition of the ideal characteristics for the format of CPGs, and development and implementation of the new format. Initially, an overview of systematic reviews was conducted to map the global evidence on the effectiveness of dissemination and implementation strategies of CPGs. Among the most effective interventions, a low-cost strategy was selected to improve the format of CPGs, namely a full format and a short format. The two formats were evaluated for usefulness and acceptability by professionals who use or develop CPGs, and after several reiterations, the formats were finalized, considering the progression of care (from diagnosis of the disease to treatment, including specific technologies indicated in each stage of the disease). Related to the technical aspects, the visual presentation of the CPGs was improved, ensuring that key information was easily identified for decision-making by end users. The initial phase of implementation involved 33 clinical conditions, equating to approximately 20% of published CPGs. It is anticipated that disseminating the CPGs in the new formats will promote the accessibility of information and implementation of standardized CPGs by health professionals in the public health sector (servicing more than 210 million Brazilians). Further research should be considered to determine the impact of the use of the new CPGs formats, contributing to the knowledge base related to the implementation of guidelines in Brazil and internationally. [ABSTRACT FROM AUTHOR]