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Objectives: to analyze the practice of self-medication and the associated factors in the riverside population of the Middle Solimões river region - Amazon rainforest., Methods: a cross-sectional population-based study conducted between April and July 2015, through interviews at home., Results: the prevalence of self-medication among the riverside population was 76.3%. Analgesics and antibacterials were the main therapeutic classes used in self-medication. Self-medication proved to be associated with the male gender, young people, not having sought the health service in the last month, longer commuting from the community to the urban area and the habit of consuming allopathic medicines on their own., Conclusions: self-medication among the riverside population of Coari - Amazon may reflect the need to seek self-care by people, with the use of allopathic medicines without prescription, mainly due to the restricted access to health services.

The objective of this study was to identify the use of phosphodiesterase type 5 inhibitors among university students from the city of Sao Paulo (SP) in Brazil. Male students (n=350) replied to a questionnaire about diagnosis of erectile dysfunction, the frequency and reason for the use of phosphodiesterase type 5 inhibitors, the specific medication used, whether their use was accompanied by a medical prescription and any reported side-effects. The results shows that a total of 53 (14.7%) students had already used this kind of medication without a prescription or medical diagnosis for erectile dysfunction, of which 53% reported using sildenafil, 37% tadalafil and 10% vardenafil. The main adverse side-effects reported were headache (23%) and flushing (10%) and the main reasons for using the inhibitor were curiosity (70%) and erectile improvement (12%).

Representations related to self-medication were investigated, seeking to identify contextual elements that can reinforce or inhibit such practice. An anthropological approach based on the model of signs, meanings, and actions was used. Twenty-nine inhabitants from the town of Bambuí, Minas Gerais State, Brazil, were interviewed (17 women and 12 men), selected among participants in a health survey that had been on medication in the previous 90 days. The research focused on the identification of different types of self-medication practiced by the interviewee or by a relative, and then "ways of thinking and behaving" associated with this practice were investigated. The influence of pharmacists/drugstore sales attendants as well as family and friends, perception of the health problem as transitory and a minor issue, familiarity with and easy access to certain pharmaceuticals, as well as difficulties in access to (and negative assessment of) health care were determinant factors for self-medication.