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Schistosomiasis is a neglected tropical disease caused by parasitic worms of the genus Schistosoma. In Brazil, there are reports of infection by the Schistosoma mansoni species, which has the Biomphalaria glabrata snail as one of its intermediate hosts. The present work aimed to test the effects of different Abelmoschus esculentus seed extracts and fractions on adults and embryos of B. glabrata and S. mansoni cercariae. A total of four crude extracts and thirteen fractions with different organic solvents were used for the bioassays. The extracts were analyzed using high-performance liquid chromatography coupled to mass spectrometry. Molluscicidal activity was assessed in 24-well plates, after which the LC50 and LC90 were calculated. Assays with B. glabrata embryos and S. mansoni cercariae were also performed. These findings indicate the presence of flavanoids in the hexane, ethyl acetate, and ethanol crude extracts. For the molluscicidal activity assays, eight fractions had an LC90 value less than that recommended by the WHO. The methanol fraction of the dichloromethane extract (FrMeOH EDM) had the most promising results, with an LC90 of 37.15 mg/L and 100% mortality in embryos of B. glabrata and cercariae. FrMeOH, EDM, and other fractions are possible candidates for new drugs for the combat of schistosomiasis. [ABSTRACT FROM AUTHOR]

The present study aimed to assess the potential impact of total species richness on the functional redundancy, utility, and versatility of plant species. For this purpose, two study areas were delineated, a wet forest and a dry forest, where phytosociological surveys were conducted. The results indicate parity in terms of the proportion of useful species between the areas. In line with our initial expectations, our findings revealed greater versatility among species in the less rich area; thus, more uses were attributed to a single species. We found no significant relationship between utilitarian redundancy and the analyzed environments in any of the plant use categories. Based on the evidence gathered, we believe that resource selection by human communities might ultimately be conditioned by local species availability rather than by underlying utilitarian potential. [ABSTRACT FROM AUTHOR]

Groundwater pollution is a current issue that may result in considerable negative effects on human health and the ecological balance. In the present study, the authors evaluated pollutants in groundwater in Maricá Municipality, located on the east side of Rio de Janeiro state in Brazil. The evaluated parameters were temperature, pH, electrical conductivity, Eh, dissolved oxygen, chlorides, nitrates, dissolved organic carbon, total inorganic carbon, phosphates, and total and thermotolerant coliforms. Due to the large number of evaluated points, they were divided into zones according to the respective hydrographic basin. The local accelerated urbanization accompanying income from oil production has led to uncontrolled population growth and associated groundwater pollution. The results of the present study suggest that sewage pollution of Maricá groundwater is already a significant issue. The lack of investment in basic sanitation has led to an imbalance in the local groundwater reservoir. In certain locations of the municipality, dissolved organic carbon (DOC), nutrient, and bacteria concentrations increase and spread in the aquifers because of domestic waste disposal. As aquifers are the main source of freshwater for the residents, contamination of them represents a potential threat to local public health. [ABSTRACT FROM AUTHOR]

Background: Dental fear affects children's oral health; there is, however, no evidence regarding the pathways linking possible predictors for its occurrence. Aim: This study aimed at exploring the direct and indirect effects of sociodemographic, clinical, behavioural and psychosocial factors on the development of dental fear in schoolchildren over time. Design: This is a prospective cohort study, with 10 years of follow‐up. The first assessment started in 2010 (T1) with a sample of 639 children aged 1–5 years from Southern Brazil. For this study, the follow‐up (T2) of these individuals was performed in 2020. Dental fear was assessed at T2 using the Brazilian version of the Children's Fear Survey Schedule–Dental Subscale (CFSS–DS). Socio‐economic, demographic, psychosocial and oral health measures were collected in both assessments. A structural equation model was performed to assess the direct and indirect pathways among variables at T1 and T2 to predict the CFSS–DS scores at T2. Results: Of the 639 children, 429 were re‐evaluated at T2. Higher levels of untreated dental caries, younger individuals, dental visits for nonroutine reasons and low sense of coherence at T2 directly impacted dental fear at T2. Considering the indirect effects, the presence of dental caries and low household income at T1 indirectly impacted higher levels of dental fear over 10 years via dental caries at follow‐up. Conclusion: Our findings suggest that socio‐economic, demographic, clinical, psychosocial and behavioural conditions can influence dental fear from childhood to adolescence. [ABSTRACT FROM AUTHOR]

Maize is a crop of significant economic importance. In the northeast region of Brazil, it serves as the foundation of family support for the majority of farmers. However, achieving high levels of productivity requires an adequate water supply throughout its growth cycle. The northeast semi-arid region experiences low rainfall and high potential evapotranspiration, directly affecting maize development and leading to severe declines in productivity. In this study, genetic selection and proteomic analysis are proposed as a strategy to identify the tolerance of maize cultivars against water stress. The experiments were conducted under two water regimes using randomized block designs with three replicates. Development and productivity traits were evaluated, and genetic parameters were estimated using mixed linear models. Selection for water stress tolerance was based on the harmonic mean of the relative performance of genotypic values. Total protein extraction from maize leaves followed the protocol established by the phenol method, and peptides were analyzed through mass spectrometry. The AG8677P cultivar demonstrated remarkable productivity under drought stress conditions, and proteins related to various fundamentally important biological processes for the tolerance mechanism were identified. The combination of genetic selection with proteomic analysis proves to be an efficient strategy, even in the face of limited resources and a small number of treatments. [ABSTRACT FROM AUTHOR]

Improving species delimitation and knowledge on species complexes is crucial for many areas of study in Biology, especially conservation. Integrative taxonomy contributes to this topic by using different approaches to better delineate taxonomic boundaries. Metternichia (Solanaceae), historically a monospecific genus, has a geographic range that comprises contrasting environments. Metternichia principis was described as having two varieties: the typical variety, found in the humid forests of eastern Brazil (Atlantic Forest region), and M. principis var. macrocalyx, which presents a larger calyx and inhabits mostly semi-arid areas (Caatinga region). In this study, we tested the validity of such groups by integrating environmental, phenological, morphometric, and palynological data; applying uni- and multivariate tests; and evaluating the conservation status of each taxon. Our results support the recognition of two morphological groups within Metternichia, largely in agreement with the original circumscription of the varieties. Multivariate analyses clearly indicate different ecological niches, with each taxon inhabiting environments with distinct mean annual precipitation and temperature. Phenological data show some differences between the varieties regarding months with the highest number of flowering and fruiting records. In general, M. principis var. macrocalyx presents larger flower and pollen characters, and smaller fruit characters compared to the typical variety. Based on these findings, we elevate the variety to the status of species, as the new combination Metternichia macrocalyx. Following IUCN guidelines, both taxa are here preliminarily considered endangered (EN). [ABSTRACT FROM AUTHOR]

Port sites represent one of the most impacted coastal areas; this impact is due to intensive anthropogenic pressures. In addition to the port complex itself, associated activities, such as indiscriminate disposal of pollutants, including trace metals, affect the local ecosystem. Macroinvertebrate benthic communities are one of the most effective bioindicators of environmental health because of their importance as a primary food source for many fish, birds, and mammals, as well as their influence on sediment stability and geochemical composition. This article evaluates the benthic macrofauna in the Santos Estuarine System (SES), the location of the Santos Port Complex (SPC), linking trace metal levels to differences in microbenthic community structure and pollutant bioavailability. The distribution of Cd, Ni, and Pb was directly related to organic matter deposits, while Cu and Zn appeared to result from port activities. The SES contained a poor benthic macroinvertebrate community, resulting from the contaminated muddy sediments. A significant negative correlation was found between the macrobenthic diversity and concentrations of Cu in the soluble phase; this implied the pollution-induced degradation of the macrobenthos in SES. [ABSTRACT FROM AUTHOR]

Background Studies have revealed high prevalence rates of Trichomonas vaginalis in men and women worldwide. In Brazil, where reporting is not mandatory, the true prevalence rate is unknown. This study determined the prevalence of the parasite in women attending public health units in the city of Uberlândia, Minas Gerais, Brazil, identifying possible risk factors for infection, and also compared three diagnostic techniques for detecting the parasite. Methods Samples of vaginal secretions collected from 742 women attending public health units were analyzed by direct wet mount examination, culture and smear test. Epidemiological questionnaires were administered. Results Of the total of 742 samples analyzed, 19 (2.6%) tested positive for T. vaginalis. The variables significantly associated with infection were: being of black ethnicity, smoking, having knowledge about sexually transmitted diseases and presenting clinical signs. The culture method was considered the gold standard test. Conclusions Although there are programs to control other sexually transmitted diseases, there are none for trichomoniasis. The results of this study indicate the presence of T. vaginalis in the female population, and points to the need for more research in Brazil to gain a better understanding of the profile and epidemiology of the parasite. [ABSTRACT FROM AUTHOR]

Abstract: This article aims to evaluate the use of hydroelectric potential in Brazil and the expansion of the hydroelectric power stations in Amazon, in the northern region of the country, highlighting the vulnerabilities, the impacts and the adaption possibilities of the hydroelectric energy in face to increasing socio-environmental demands and to global climate change in progress. The analysis indicates the nearly exhausted hydroelectric potential in other regions of the country, transforming the Amazon into a new “hydroelectric barn” or “new hydroelectric frontier”. The integrated management of reservoirs and multiple uses of water, the new institutional and regulatory arrangements, the technological and economic opportunities of the sector, and finally, integration with neighboring countries are treated to subsidize a sustainable use of hydroelectric potential in the Amazon. [Copyright &y& Elsevier]

Abstract  The majority of indices proposed to predict the erodibility of tropical soils is based on empirical tests and often fail to reveal the actual erodible properties of soil. This investigation analysed 244 samples of tropical soils collected in So Paulo State (Brazil) where engineering geological mapping was available, such that the results of the erodibility testing could be linked with several index properties of the soils. These relationships were analysed in three-dimensional graphics. The results showed that the most significant attributes in tropical soil erodibility were loss of mass by immersion, specific gravity and water absorption index. The cation exchange capacity, when associated with loss of mass by immersion, allowed the identification of 96% of the samples with low and 88% of those with high erodibility, demonstrating that simple indices can be successfully used to predict tropical soil erodibility. [ABSTRACT FROM AUTHOR]

[Display omitted] • Acoustic detection of cicadas of the species Quesada gigas is investigated. • A hybrid algorithm based on EMD-PFE-SVM methods is proposed. • Influence of EMD stopping criteria on classification is investigated. • Algorithm performance is validated by more than 18 million tests combining parameters. • Obtained performance is over 90.79% for all stopping criteria and test series. The sounds emitted by various insect species are highly specific and, thus, can be used as a way to acoustically characterize them. Consequently, acoustic insect detection has been widely studied by the scientific community in the field of pattern recognition. In Brazil, the cicada species Quesada gigas is considered a pest in coffee plantations, because the insects feed on the sap of the plants and can cause losses to farmers in mass attacks. Based on the fact that the most striking feature of cicadas is the emission of sounds for breeding purposes, this paper presents an alternative algorithm for acoustic detection of cicadas. The algorithm combines sound feature extraction with feature analysis based on Empirical Mode Decomposition (EMD) and Paraconsistent Feature Engineering (PFE), respectively, followed by a classification step based on a Support Vector Machine (SVM). Specifically, a study on the influence of eight EMD stopping criteria on the classification of sounds is presented. The results show that the proposed methodology can obtain accuracy values above 98 % considering the Energy Difference Tracking (EDT) stopping criterion, vectors with 18 features and at least 46 % of the vectors for SVM training. In the computational cost aspect, the stopping criterion Standard Deviation (SD) stands out, providing accuracy values above 96.67 % for vectors with only two features. These results show that this study is feasible for Internet of Things applications, favoring the development of detection devices for field use with long-lasting autonomy. Technologies like these can enable the implementation of more and more daring projects involving Smart Farms and e-waste, aiming to reduce impacts to the environment. Suggestions for future work based on the PFE are also presented. [ABSTRACT FROM AUTHOR]

Although protected areas (PAs) are designed to safeguard natural ecosystems from anthropic modifications, many PAs worldwide are subjected to numerous human-induced impacts. We evaluated whether the establishment of PAs in the Upper Paraná River floodplain region could reduce anthropic landscape changes and whether there is a difference in protection when using different PA restriction categories. We analyzed the overall landscape dynamics using 30 years of land-use time series data and evaluated the change intensity via a partial land-use intensity analysis. Despite the increasing landscape anthropization, the PAs seemed to relieve the general change process, protecting natural areas mainly from agricultural expansion. Concerning the degree of use restriction, more restricted protection led to less human-induced changes. Finally, accessing PA effectiveness is a multidisciplinary challenge for researchers; however, this knowledge is crucial to avoid misunderstandings or poorly crafted public policies or decisions that may harm the environment., (© 2023. The Author(s).)

Aim: To evaluate the moderating effect of the sense of coherence (SOC) in the relationship between racial discrimination and oral health-related quality of life (OHRQoL) in schoolchildren., Methods: This is a cross-sectional study nested in a cohort performed in southern Brazil. OHRQoL was assessed using the short version of the Child Perceptions Questionnaire 11-14 (CPQ11-14). The perception of racial discrimination was measured using a question contained in the Bullying Questionnaire by Olweus, and SOC through the shortened version of the 13-item Sense of Coherence Scale. Sociodemographic and dental caries following the International Caries Detection and Assessment System (ICDAS) characteristics were also collected. A simple slop test and Poisson regression analysis were performed to test the interaction effects of the predictors on OHRQoL., Results: A total of 429 schoolchildren were included in this study. About 6.7% reported had perceived racial discrimination. The simple slope test indicated that the negative effects of racial discrimination on OHRQoL were significant under different SOC levels. Among schoolchildren who suffered racial discrimination, those who had higher SOC reported lower impact on OHRQoL when compared to those with low SOC., Conclusion: SOC can be considered a moderating variable in the relationship between racial discrimination and OHRQoL., Clinical Significance: These findings highlight that psychosocial factors such as SOC could attenuate the impact of perceived discrimination on OHRQoL in adolescence., Competing Interests: Declaration of Competing Interest The authors have no conflicts of interest in relation to the products or methods mentioned herein., (Copyright © 2023. Published by Elsevier Ltd.)

Objectives: The Bournemouth Questionnaire is a comprehensive and short form multidimensional instrument developed to evaluate the health status of individuals with low back pain. The objective of this study was to verify the construct validity and the test-retest reliability of the Brazilian version of Bournemouth Questionnaire in individuals with low back pain., Methods: This is a methodological study that included 65 patients with low back pain. The Brazilian Bournemouth Questionnaire was applied twice, and the test-retest reliability was assessed using intraclass correlation coefficient (ICC), standard error of measurement (SEM), minimum detectable change (MDC), and internal consistency. The construct validity of the Brazilian Bournemouth Questionnaire was assessed using the numeric pain rating scale (NPRS) and also with the following questionnaires: Roland-Morris Questionnaire (RMDQ), Oswestry Disability Index (ODI), and the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36)., Results: The total score of the Brazilian Bournemouth Questionnaire showed ICC of 0.82 (95% CI: 0.72, 0.90), Cronbach´s alpha of 0.85, SEM of 5.97, and MDC of 15.54, without evidence of ceiling and floor effects. The total score of the Brazilian Bournemouth Questionnaire was correlated to the NPRS for current (r = 0.64), highest (r = 0.49), and lowest (r = 0.67) pain as well as scores on the RMDQ (r = 0.58), ODI (r = 0.42), and SF-36 (r = -0.58)., Conclusion: The total score of the Brazilian version of the Bournemouth Questionnaire is valid and reliable to be used with patients with low back pain., (Copyright © 2020 Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia. Publicado por Elsevier España, S.L.U. All rights reserved.)

Seabirds are used as bioindicators of marine ecosystems, especially for quantifying and tracking pollution sources. The objective of this study was to evaluate the contamination in feathers of young kelp gulls by lead (Pb), chromium (Cr), mercury (Hg) and zinc (Zn) on three islands of southern Brazil. The highest values for Pb (2.1310 μg g -1 ) and Hg (0.0010 μg g -1 ) were observed in Lobos. Zn was common in all samples with a median around 41.7487 μg g -1 and Cr values were below the quantification limit (0.0300 μg g -1 ). The Kruskal-Wallis test indicated significant differences in Pb (H = 21.84; p < 0.05) and Zn (H = 958.80; p < 0.05), but no differences were observed in Cr (H = 3.08; p < 0.05) and Hg (H = 3.0; p < 0.05). This study was important to show the impact of trace element pollutants on the seabird communities and oceans., (Copyright © 2020 Elsevier Ltd. All rights reserved.)

Introduction: Coccidioidomycosis, a disease caused by Coccidioides immitis or Coccidioides posadasii, is endemic in arid climatic regions in Northeast Brazil. Its prevalence is higher among young adult males living in rural areas. Existing literature about this disease in Ceará, a Northeast Brazilian state, are scarce. Here, we aimed to outline the clinical and epidemiological profiles, radiological patterns, and therapeutic responses of patients with coccidioidomycosis in a reference center in Ceará, Brazil., Methods: This is a descriptive study with quantitative analysis. Patients who underwent medical follow-up in São José Hospital of Infectious Diseases and received confirmed mycological diagnosis of coccidioidomycosis between January, 2007 and December 2017 were included. Epidemiological, clinical, radiological, and therapeutic response data were collected from medical charts., Results: Thirty patients were included. The patients were males with median age of 30 years, and 73% were considered to have high-risk exposure to Coccidioides owing to professional activities. Cough (96.7%), dyspnea (63.3%), fever (86.7%), and pleuritic pain (60%) were the most prevalent clinical manifestations. Interstitial pattern (91.3%) was the most frequent pulmonary radiological finding. Fluconazole, amphotericin B, and itraconazole were administered for treatment (in 82.1%, 42.8%, and 21.4% of cases, respectively). A favorable outcome was observed in 83.8% of patients., Conclusions: Coccidioidomycosis was more prevalent in the central and southern regions of the State of Ceará. Understanding the local epidemiology and clinical manifestations of the disease, in addition to the pulmonary radiologic findings, may aid the early detection of coccidioidomycosis and facilitate early diagnosis.

The objective of this study was to compare the reproductive performance, milk yield and composition, and udder health and conformation traits of Holstein (Ho), F1, and R1 crossbred Ho × Simmental (Sim) cows. Three commercial dairy farms in south Brazil were used as the research units. All farms held Ho, F1, and R1 crossbred Ho × Sim (¾ Ho × ¼ Sim and ¾ Sim × ¼ Ho) cows. The collection of milk samples and evaluation of udder conformation traits occurred during four visits to each farm. In addition to the actively collected data, retrospective reproduction records of the farms served as the basis for the statistical analysis using analysis of variance models using SAS. The F1 crossbred Ho × Sim cows and ¾ Sim (first rotational crossbreeding generation = R1 using Sim semen) cows had a shorter calving interval and calving to first service interval compared to the Ho cows (P < 0.0001). Milk yield did not differ among the genetic groups except for R1 (¾ Sim) that produced approximately 10% less milk than the other groups (P = 0.0245). Fat plus protein yield and somatic cell score did not differ among the genetic groups. Ho cows had shallower udders (P < 0.0001) and a higher udder clearance (P < 0.0001) than the other groups. F1 and R1 crossbred Ho × Sim cows had shorter reproduction intervals than purebred Ho cows. Although udder conformation traits lacked high-quality scores in crossbred cows, somatic cell scores reached the same level as in purebred Ho cows.

Context: Despite the popularity of soccer at the male first-division youth level, data on the incidence of injuries in Brazil are limited., Objective: To prospectively study the injury profile of male first-division youth soccer players during 1 season (January to December 2017)., Design: Descriptive epidemiology study., Setting: Data compiled at a youth soccer academy., Patients or Other Participants: The study involved 228 players between 10 and 20 years old from a first-division Brazilian soccer academy., Main Outcome Measure(s): Injury incidence rate was reported as the number of injuries divided by overall exposure (training and match hours) multiplied by 1000. The rate ratio (injury incidence rate during matches in relation to training) was also calculated. Time-loss injuries (ie, physical complaints sustained during soccer matches or training that resulted in a player being unable to take part in soccer training or match play) during the season were recorded., Results: A total of 187 injuries were documented in 122 players (65.2%). During the season, 100 389 hours of exposure (5995 hours of match play and 94 394 of training) were registered. The overall injury incidence rate was 1.86 per 1000 hours. In total, 4792 days were lost from soccer activities. The majority of injuries were noncontact thigh muscle disorders and ankle sprains. Injury incidence was greater in matches than in training, and the oldest age group (under 20 years old) had the highest injury incidence rate in matches, while the under 17-year-old group had the highest injury incidence rate in training sessions (22.48 and 3.05 per 1000 hours, respectively)., Conclusions: Muscle injury incidence rates observed among Brazilian soccer athletes under 20 years old were similar to those reported in professional players. Preventive measures are recommended to reduce injury rates. Additionally, the number of injuries incurred during training was high compared with match play, and training programs need to be assessed so that injury prevention can be improved.

The purpose of this study was to evaluate the effectiveness of photodynamic therapy as complementary therapy to mechanical instrumentation on periodontal residual pockets. This longitudinal, prospective, double-blind and controlled split-mouth clinical trial included one hundred and fourteen residual periodontal sites with probing depth ≥ 4 mm and bleeding on probing, which were distributed into two groups: 57 in the test group (SRP + aPDT) - using a low power laser application Therapy XT (DMC Equipamentos Ltda, São Carlos, São Paulo, Brazil) with operational parameters of 660 nm and 110 mW for 15s, and 57 in the control group (SRP). Oral hygiene conditions were evaluated, through the Visible Plaque Index (VPI) and Gingival Bleeding Index (GBI), as well as periodontal clinical outcomes, comprising the Bleeding on Probing (BOP), Probing Depth (PD) and Clinical Attachment Level (CAL) at baseline and after 3 months. Decrease of 17.74% was observed for the VPI after 3 months of follow-up, while the GBI was reduced by 19.91%, thus indicating statistically significant decreases for both parameters (p < 0.001). Decreases in VPI per site, BOP and PD and CAL gain between T 0 and T 3 in both treatment groups (p < 0.001) were observed, but no statistically significant intergroup differences were found (p > 0.05). Within the parameters used in this study, adjuvant aPDT to SRP did not lead additional benefits regarding the assessed clinical parameters after three months., Competing Interests: Declaration of Competing Interest The authors declare that they have no conflict of interest., (Copyright © 2019 Elsevier B.V. All rights reserved.)

This study aimed to assess the association of demographic conditions, socioeconomic status, clinical variables, and psychosocial factors with the number of filled teeth in adolescents from public schools. This cohort study comprised 1,134 12-year-old adolescents enrolled in public schools in Santa Maria, Brazil, in 2012. They were followed-up in 2014, where 743 individuals were reassessed (follow-up rate of 65.52%) for the number of filled teeth. Data were collected via dental examinations and structured interviews. Demographic and socioeconomic characteristics were collected from parents or legal guardians. The psychosocial factor comprised students' subjective measurement of happiness (Brazilian version of the Subjective Happiness Scale - SHS). Dental examinations were performed to assess the number of filled teeth through decay, missing, and filled teeth index (DMF-T). Unadjusted and adjusted Poisson regression analyses were performed to assess the association between baseline variables and filled teeth at follow-up. The number of filled teeth in 2012 and 2014 were 193 (17.02%) and 235 (31.63%), respectively. The incidence of filled teeth in 2014 was 42 (5.65%). Adolescents with untreated dental caries, those who visited the dentist in the last 6 months, those that exhibited being happier, and those who had filled teeth at baseline were associated with a higher number of filled teeth at follow-up. We conclude that the number of filled teeth in adolescents was influenced by clinical and psychosocial factors, emphasizing the need to focus on oral health policies in individuals with higher disease burden and those who feel psychologically inferior.

Objective To analyse how therapeutic play structured in a nursing care model contributes to the care of hospitalised children. Method This is a qualitative study based on convergent care research (CCR). Seven children participated in the study. Data were collected in September and October of 2014 by means of interviews with open-end questions and participant observation of therapeutic and dramatic play sessions and/or instructional play sessions based on the stages "Welcoming/Playing/Concluding" of the nursing model Care with Play. Data were analysed according to the analysis and interpretation stages of the CCR. Results The following three categories emerged: Meanings attributed by the child to hospitalisation and its influence on nursing care; Perception of the therapeutic procedures through therapeutic play, and Importance of the family in care. Final considerations It is concluded that the application of therapeutic play structured in the care model contributes to systematic and specialised nursing care.

Background: Actinic cheilitis (AC) is a potentially malignant disorder of the lip caused by chronic exposure to ultraviolet radiation from the sun., Objectives: To evaluate the clinical, demographic, morphological and therapeutic management in AC cases data associating to the histopathological grading., Methods: Demographic, clinical and management data of 161 patients with AC were analyzed. In biopsied cases, two calibrated examiners performed histopathological grading by binary system., Results: There was a prevalence of males (79.5%), aged 40 years or older (77.5%), light-skinned (85.7%), experiencing occupational exposure to sunlight (80.3%), with AC presenting clinically as white lesions (33.6%). Conservative treatment was adopted in 78 cases and biopsy in 83 cases (60.2% graded as low-risk AC). There were no significant associations between histopathological grading and gender (p= 0.509), age (p=0.416), ethnicity (p=0.388), occupational exposure to sunlight (p=1.000) or clinical presentation (p=0.803)., Conclusion: This study reinforces the hypothesis that demographic and clinical characteristics of AC are not related to histopathological grading. Advice on protection from sun exposure should be encouraged to avoid progression of AC and invasive therapies.

This paper describes the development of a speech-in-noise test for hearing screening and surveillance in Brazilian Portuguese based on the evaluation of suprathreshold acuity performances. The SUN test (Speech Understanding in Noise) consists of a list of intervocalic consonants in noise presented in a multiple-choice paradigm by means of a touch screen. The test provides one out of three possible results: "a hearing check is recommended" (red light), "a hearing check would be advisable" (yellow light), and "no hearing difficulties" (green light) (Paglialonga et al., Comput. Biol. Med. 2014). This novel test was developed in a population of 30 normal hearing young adults and 101 adults with varying degrees of hearing impairment and handicap, including normal hearing. The test had 84% sensitivity and 76% specificity compared to conventional pure-tone screening and 83% sensitivity and 86% specificity to detect disabling hearing impairment. The test outcomes were in line with the degree of self-perceived hearing handicap. The results found here paralleled those reported in the literature for the SUN test and for conventional speech-in-noise measures. This study showed that the proposed test might be a viable method to identify individuals with hearing problems to be referred to further audiological assessment and intervention.