1. Assessing the global threat from Zika virus.
- Author
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Lessler J, Chaisson LH, Kucirka LM, Bi Q, Grantz K, Salje H, Carcelen AC, Ott CT, Sheffield JS, Ferguson NM, Cummings DA, Metcalf CJ, and Rodriguez-Barraquer I
- Subjects
- Animals, Biomedical Research trends, Brazil, Culex virology, Drug Design, Female, Global Health, Humans, Incidence, Phylogeny, Pregnancy, Pregnancy Complications, Infectious virology, Public Health, Zika Virus Infection complications, Microcephaly virology, Zika Virus classification, Zika Virus pathogenicity, Zika Virus physiology, Zika Virus Infection prevention & control, Zika Virus Infection transmission
- Abstract
First discovered in 1947, Zika virus (ZIKV) infection remained a little-known tropical disease until 2015, when its apparent association with a considerable increase in the incidence of microcephaly in Brazil raised alarms worldwide. There is limited information on the key factors that determine the extent of the global threat from ZIKV infection and resulting complications. Here, we review what is known about the epidemiology, natural history, and public health effects of ZIKV infection, the empirical basis for this knowledge, and the critical knowledge gaps that need to be filled., (Copyright © 2016, American Association for the Advancement of Science.)
- Published
- 2016
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