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Background: The COVID-19 pandemic produced alarming rates of disease and mortality globally, yet few nations were as severely impacted as Brazil. The pandemic also exposed and exacerbated persistent forms of structural violence across Brazil, which complicated gender-based violence (GBV) prevention and response efforts. While structural violence is not new, the systemic pressure and uncertainty introduced by COVID-19 intensified the detrimental impact of structural violence on the lives of Brazilians impacted by GBV. This work qualitatively investigated how the COVID-19 pandemic amplified structural violence and GBV in Brazil., Methods: We analyzed key informant interviews (KII) conducted with 12 service providers working in sectors related GBV prevention and response in Roraima, Boa Vista, and Rio de Janeiro. Interviews were audio-recorded, transcribed, and translated from Portuguese or Spanish into English, before applying deductive and inductive coding approaches through a collaborative data reduction process. The theoretical lens of structural violence outlined by Farmer and Rylko-Bauer guided the thematic development., Results: Analyses identified three themes. First, structural violence manifests as policies of inaction and erasure, which reduce the opportunity for upward social mobility among GBV survivors including Black women, trans persons, and people who live in the favelas. Policies of inaction and erasure fail to acknowledge/adequately respond to the significant health and safety needs of these communities. Second, structural violence is a fundamental cause of violence against women and children. Finally, service providers described community driven responses that address the dire survival needs (i.e., food insecurity) imposed by COVID-19, within a context of structural violence. These community driven responses were innovative, agile, and based on dire needs expressed to, and observed by, the service providers interviewed., Conclusion: This analysis highlights how the COVID-19 pandemic exacerbated existing forms of structural violence prevalent throughout Brazil. Findings stress the urgency with which the Brazilian government and international organization must act to support community driven programs that strive to address the most basic human needs., (© 2023. BioMed Central Ltd., part of Springer Nature.)

Preventing, detecting, and monitoring invasive marine species is a big challenge as it is not possible to visualize all invasion extensions. Their early detection may be the best chance to achieve eradication. The Indo-pacific scleractinian coral Tubastraea coccinea invasion in the Atlantic dates from the late 1930s. Since then, disruptive populations were found along ~8.000 km of west Atlantic, and in the Canarian Islands of Spain (east Atlantic), related to vessel fouling in the oil and gas industry. Their impacts have been noticed from endemic species to ecosystems. In Brazil, initiatives to control Tubastraea spp. have been done mostly by local environmental managers and researchers, but recently a National Plan for Prevention, Control and Monitoring (NPPCM) for Tubastraea spp. was approved. We applied an Individual-based Model within the invasion history of Tubastraea coccinea in its southern distribution limit in the Atlantic, on the rocky shore of the Arvoredo Biological Marine Reserve. We indicated hotspots for the occurrence of possible emerging invasion sites in the region and expect to support ongoing monitoring programs in defining priority areas for their early detection. The model is easily replicated and might be a valuable tool for decision makers., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2022 Elsevier Ltd. All rights reserved.)

Objective: The aim of this study was to investigate the association between single-nucleotide polymorphisms (SNPs) in vitamin D metabolic pathway genes, serum 25-hydroxyvitamin D [25(OH)D] concentrations, and leukocyte telomere length (LTL) in Brazilian adults., Methods: The study population comprised 461 participants (33-79 y of age; 51% women) from the Pró-Saúde Study, a cohort of civil servants at a university campus in Rio de Janeiro, Brazil. LTL, genotypes of vitamin D-related SNPs (rs12785878, rs10741657, rs6013897, and rs2282679), and serum 25(OH)D concentrations were determined cross-sectionally. Differences in age- and sex-adjusted LTL means by categories of genotypes and 25(OH)D serum concentrations were evaluated. LTL associations with genotypes and 25(OH)D were investigated using multiple linear regression models adjusted for sociodemographic characteristics and markers of health behavior., Results: Participants with CC genotype (rs2282679) had shorter age- and sex-adjusted mean LTL than those with AC and AA genotypes (mean ± SE: 0.51 ± 0.03, 0.58 ± 0.01 and 0.5 ± 0.01, respectively, P < 0.05). In adjusted analyses, the CC genotype (rs2282679) was inversely associated with LTL (β = -0.061; 95% confidence interval, -0.120 to -0.001). Other vitamin D-related SNPs and serum 25(OH)D concentrations were not associated with LTL., Conclusions: Genetic variations in the gene encoding vitamin D binding protein (GC - rs2282679) were associated with LTL, suggesting an influence of vitamin D status on telomere length that may start early in life., (Copyright © 2019 Elsevier Inc. All rights reserved.)

The Amazon area has been increasingly suffering from anthropogenic impacts, especially due to the construction of hydroelectric power plant reservoirs. The analysis and categorization of the trophic status of these reservoirs are of interest to indicate man-made changes in the environment. In this context, the present study aimed to categorize the trophic status of a hydroelectric power plant reservoir located in the Brazilian Amazon by constructing a novel Water Quality Index (WQI) and Trophic State Index (TSI) for the reservoir using major ion concentrations and physico-chemical water parameters determined in the area and taking into account the sampling locations and the local hydrological regimes. After applying statistical analyses (factor analysis and cluster analysis) and establishing a rule base of a fuzzy system to these indicators, the results obtained by the proposed method were then compared to the generally applied Carlson and a modified Lamparelli trophic state index (TSI), specific for trophic regions. The categorization of the trophic status by the proposed fuzzy method was shown to be more reliable, since it takes into account the specificities of the study area, while the Carlson and Lamparelli TSI do not, and, thus, tend to over or underestimate the trophic status of these ecosystems. The statistical techniques proposed and applied in the present study, are, therefore, relevant in cases of environmental management and policy decision-making processes, aiding in the identification of the ecological status of water bodies. With this, it is possible to identify which factors should be further investigated and/or adjusted in order to attempt the recovery of degraded water bodies., (Copyright © 2014 Elsevier B.V. All rights reserved.)

Objective: To analyze ethical standards considered by health-related scientific journals, and to prepare the Ethics Requirement Score, a bibliometric index to be applied to scientific healthcare journals in order to evaluate criteria for ethics in scientific publication., Methods: Journals related to healthcare selected by the Journal of Citation Reports™ 2010 database were considered as experimental units. Parameters related to publication ethics were analyzed for each journal. These parameters were acquired by analyzing the author's guidelines or instructions in each journal website. The parameters considered were approval by an Internal Review Board, Declaration of Helsinki or Resolution 196/96, recommendations on plagiarism, need for application of Informed Consent Forms with the volunteers, declaration of confidentiality of patients, record in the database for clinical trials (if applicable), conflict of interest disclosure, and funding sources statement. Each item was analyzed considering their presence or absence., Result: The foreign journals had a significantly higher Impact Factor than the Brazilian journals, however, no significant results were observed in relation to the Ethics Requirement Score. There was no correlation between the Ethics Requirement Score and the Impact Factor., Conclusion: Although the Impact Factor of foreigner journals was considerably higher than that of the Brazilian publications, the results showed that the Impact Factor has no correlation with the proposed score. This allows us to state that the ethical requirements for publication in biomedical journals are not related to the comprehensiveness or scope of the journal.

Those who favor and those who oppose the interruption of pregnancy with anencephalic fetuses answer the question 'what is the right to life?' differently. Those in favor argue that life exists only when it is 'viable'; that is to say, when cerebral activities occur or may occur. Those who oppose it argue that it is not possible to describe 'life' as residing in a particular quality, since life 'exists from conception'. In fact, in both cases, the noun 'life' is being defined by a particular quality, either as 'viable' or as 'existing from the time of conception'. Also, simply saying that 'there is life' cannot count as a neutral answer since those who utter such a sentence employ an unspecified criterion to establish if there is life or not. There are two possible ways to investigate this controversial matter: either we look for a definition of 'life' which is neutral and objective and does not reside in a particular quality or we try to establish whether or not the search for a neutral point of view can lead to a satisfactory answer. In this article we explore the argument against the interruption of pregnancy - as defined above - in order to show 1) the impossibility of establishing a neutral point of view regarding knowledge; 2) the existence of a psychological motivation which justifies the longing for an absolute criterion for the evaluation of human actions. This psychological motivation is analyzed from a Nietzschean perspective., (© 2011 Blackwell Publishing Ltd.)

Purpose: To analyze the association between black people and left ventricular hypertrophy (LVH) in the absence of hypertension and/or other cardiopulmonar disease., Methods: Data were collected from necropsies carried out in the Anatomopathologic Service (APS). Hospital Edgard Santos from 1970 to 1986, Salvador. It were included only subjects at ages > or = 20 years and free of hypertension and any cardiopulmonar disease. A LV wall > 1.6cm was considered as LVH (standardized criteria of the APS). Controls variables were age, sex, and absence of the mentioned diseases. It was used a case-control epidemiological study design and the association measured by "odds ratio" (OR) for no matched case-control study., Results: From the 208 subjects studied, 48 (23.1%) had LVH. There was no difference in the frequency of right ventricular hypertrophy between cases and controls (p > 0.05). The mean of heart weight was higher for LVH cases (p < 0.001), but there was no evidence of association between blacks and LVH (OR = 1.05, p > 0.05 and confidence interval at 95% = 0.8, 1.31. The highest odds possible for the association in this study (assuming that all 3 LVH losses were black subjects) would be 1.5, also no statistically significant., Conclusion: In the absence of hypertension and other cardiopulmonar diseases, LHV is common in necropsies in Salvador, Brazil, with similar frequencies in blacks, whites and mullatos and seems not be a risk factor for hypertension in black people.