1. Benefits of Multimodal Exercise Intervention for Postural Control and Frontal Cognitive Functions in Individuals with Alzheimer's Disease: A Controlled Trial.
- Author
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Andrade, Larissa P., Gobbi, Lilian T. B., Coelho, Flávia G. M., Christofoletti, Gustavo, Riani Costa, José L., and Stella, Florindo
- Subjects
ANALYSIS of variance ,COGNITION ,POSTURAL balance ,EXERCISE ,MULTIVARIATE analysis ,HEALTH outcome assessment ,RESEARCH funding ,STATISTICAL sampling ,EFFECT sizes (Statistics) ,PRE-tests & post-tests ,REHABILITATION of Alzheimer's patients ,GERIATRIC Depression Scale ,DATA analysis software ,DESCRIPTIVE statistics - Abstract
Objective To verify the effects of a systematized multimodal exercise intervention program on frontal cognitive function, postural control, and functional capacity components of individuals with Alzheimer's disease ( AD). Design Nonrandomized controlled trial with pre- and posttraining tests in a training group and a control group. Setting Kinesiotherapy program for seniors with AD, São Paulo State University. Participants Convenience sample of older adults with AD (n = 30) were assigned to a training (n = 14; aged 78.6 ± 7.1) and a control (n = 16; aged 77.0 ± 6.3) group. Intervention The intervention program was structured with the aim of simultaneously promoting better balance and frontal cognitive capacity. The participants attended a 1-hour session three times a week for 16 weeks, whereas the control group did not participate in any activity during the same period. Measurements Frontal cognitive function was evaluated using the Montreal Cognitive Assessment, the Clock Drawing Test, the Frontal Assessment Battery, and the Symbol Search Subtest. Postural control (center of pressure area) was analyzed under four dual-task conditions. Functional capacity components were analyzed using the Timed Up and Go Test, the 30-second sit-to-stand test, the sit-and-reach test, and the Berg Functional Balance Scale. Results Intervention group participants showed a significant increase in frontal cognitive function ( P < .001, partial η
2 = 0.838), with less body sway ( P = .04, partial η2 = 0.04) during the dual tasks, and greater functional capacity ( P = .001, partial η2 = 0.676) after the 16-week period. Conclusion Intervention participants performed better on dual-task activities and had better postural balance and greater functional capacity than controls. [ABSTRACT FROM AUTHOR]- Published
- 2013
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