1. Study protocol: improving response to malaria in the Amazon through identification of inter-community networks and human mobility in border regions of Ecuador, Peru and Brazil.
- Author
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Janko MM, Araujo AL, Ascencio EJ, Guedes GR, Vasco LE, Santos RO, Damasceno CP, Medrano PG, Chacón-Uscamaita PR, Gunderson AK, O'Malley S, Kansara PH, Narvaez MB, Coombes C, Pizzitutti F, Salmon-Mulanovich G, Zaitchik BF, Mena CF, Lescano AG, Barbieri AF, and Pan WK
- Subjects
- Humans, Peru epidemiology, Ecuador epidemiology, Brazil epidemiology, Community Networks, Malaria epidemiology, Malaria prevention & control
- Abstract
Introduction: Understanding human mobility's role in malaria transmission is critical to successful control and elimination. However, common approaches to measuring mobility are ill-equipped for remote regions such as the Amazon. This study develops a network survey to quantify the effect of community connectivity and mobility on malaria transmission., Methods: We measure community connectivity across the study area using a respondent driven sampling design among key informants who are at least 18 years of age. 45 initial communities will be selected: 10 in Brazil, 10 in Ecuador and 25 in Peru. Participants will be recruited in each initial node and administered a survey to obtain data on each community's mobility patterns. Survey responses will be ranked and the 2-3 most connected communities will then be selected and surveyed. This process will be repeated for a third round of data collection. Community network matrices will be linked with each country's malaria surveillance system to test the effects of mobility on disease risk., Ethics and Dissemination: This study protocol has been approved by the institutional review boards of Duke University (USA), Universidad San Francisco de Quito (Ecuador), Universidad Peruana Cayetano Heredia (Peru) and Universidade Federal Minas Gerais (Brazil). Results will be disseminated in communities by the end of the study., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
- Published
- 2024
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