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Bangladesh Cutaneous Adverse Drug Responses (CADR) are common adverse drug reactions that can manifest in many ways and range in severity. The most typical drug allergy symptom is skin manifestation, underscoring how crucial it is to identify the offending medication and stop using it doing so could even save your life in some cases. Objective This study aims to investigate the incidence of severe and fatal cutaneous adverse medication reactions (SCAR) in hospitalized Bangladeshi patients and the prevalence of severe and fatal cutaneous adverse drug reactions (SCAR) in hospitalized patients. Methods Inpatient records from the Department of Dermatology and Venereology, Combined Military Hospital (CMH), Dhaka, were used to gather data retroactively throughout the time frame of January 2012 to December 2016. Age, gender of the patients, implicated drugs, observed drug reactions, course of treatment, and results were some variables we examined (mortality and morbidity). Results Clinical evaluation of the study participants revealed that 46% of cases were SJS, 29% were TEN, 16% were DRESS, and 10% were AGEP. The age range of 31 to 50 years saw the highest incidence (46%) of cases. Drug classes that contain anticonvulsants may have the highest incidence of SCADRs. Phenytoin caused 16% of patients' SCADRs, followed by carbamazepine in 22% of instances and phenobarbital in 14% of cases. Conclusion SCADRs have been a serious issue in healthcare for decades. The majority of SCADR is caused by medications that doctors give. SCADRs were more frequently observed with anticonvulsants from the carbamazepine and phenytoin categories. Continuous monitoring of SCADRs is necessary to develop preventive measures. [ABSTRACT FROM AUTHOR]