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Environmental physical activity (EPA) is considered as one of main regulators of human homeostasis. Evidence is growing that components of this activity through the "human factor" (i.e., changing human physiological and psychological status) can affect the dynamics of traffic accidents (TA)-the modern life epidemic. This paper presents results of studies conducted in order to reveal the potential influence of EPA [solar (SA), geomagnetic (GMA) and cosmic ray (CRA) activities] on the number of TA and related casualties in the years of the maximum and declining phase of SA cycle 23 (2000-2005). We selected the 7,160 most severe TA and their related 7,558 deaths and 1,647 severe injuries, registered in the Grand Baku Area (Azerbaijan, middle latitudes), for analysis. A significant increase of TA and victims was observed during the whole year and also during the last months of the year. The monthly numbers of TA and victims were inversely related to SA (probability p = 0.0002), and non-significantly to background GMA, but were significantly affected by major geomagnetic disturbances and storms. A strong correlation between CRA variations (cosmic ray intensity measured by ground-based neutron monitors on the Earth's surface) and the number of TA (p = 0.001) has been observed. It was found that the number of TA which occur within a month depends significantly on the particular month of the year, the CRA, and the SA levels (inverse correlation). The increase of the number of TA is also significantly linked to geomagnetic storms, but not to steady GMA. These effects can be related to changes in human functional and behavioral markers provoked by EPA influences.

Background: During the past decades, many studies were published considering cosmo-terrestrial influences on different sites of human homeostasis. The aim of this study was to summarize some of those studies in the field of cardiovascular medicine, concentrating on environmental physical activity--Solar (SA), Geomagnetic (GMA), and conversely, Cosmic Ray (CRA)--links with atherothrombosis, the basic mechanism of most vascular catastrophes in modern society., Methods: A preview of a number of comparative studies between clinical events-acute myocardial infarction (AMI), sudden cardiac death (SCD), stroke (CVA), laboratory data of coagulation, inflammation (daily, monthly), with parameters of SA, GMA, CRA, and closely linked to CRA, high energy space proton flux at high energies. The clinical and laboratory data were from studies in Lithuania and Israel. The physical data were from space-science institutions in the USA and Russia (until 1990-USSR)., Statistics: Student's t-test and Pearson correlation coefficients and their probabilities were used., Results: A significant relation was found between the level of GMA (I-IV) and blood coagulation parameters, (platelet count and aggregation, fibrinogen, INR [ratio of patient's prothrombin time to normal], inflammation markers--serum C-reactive protein (CRP), elements of anti-phospholipid syndrome, number of deaths from ischemic CVA, SCD, outpatients death from AMI. The monthly occurrence of AMI (total and all subtypes) was connected with CRA. Monthly deaths from CVA (mostly ischemic) were correlated with CRA, and both events were closely connected with atherothrombosis., Conclusion: Three basic components of atherothrombosis-blood coagulation, inflammation, atheroma disruption are connected with environmental physical activity--CRA is predominant in plaque disruption, cellular damage, electrical instability, GMA in the activation of coagulation and inflammation.

Background: Despite substantial progress in modern preventive and clinical cardiology, acute myocardial infarction (AMI) remains a central acute cardiac event. The aim of this study was to check the basic daily environmental-physical conditions accompanying the occurrence of AMIs in a specific geographic area: Baku, Azerbaijan., Material/methods: AMIs registered in the Baku area by 21 first-aid stations (n=4919) during 2003-2005 were compared with daily geomagnetic activity (GMA) levels (I(0)-IV(0)) and cosmic ray activity (CRA), described by neutron (imp/min) and solar activity. The same comparison was made for pre-admission fatal AMIs (n=440). The cosmophysical data came from space science centers in the USA, Russia, and Finland., Results: AMI morbidity followed a daily distribution according to GMA, mostly on quiet (I(0)) GMA days. A monthly comparison showed inverse relationships with solar activity and GMA and correlation with CRA. The daily clinical parameters of AMI correlated with CRA. Despite the daily rise in AMI mortality on days with the highest GMA, the days with the lowest GMA and higher CRA were predominant for AMI occurrence and pre-admission mortality. One of the possible predisposing factors can be life-threatening arrhythmia., Conclusions: The monthly number of AMIs was inversely related to monthly solar activity and correlated with CRA-neutron activity. Pre-admission AMI mortality was inversely linked with GMA. Daily AMI pre-admission mortality rose with concomitant GMA; low-GMA and higher-neutron-activity AMIs occurred much more frequently and were more strongly related to the number of fatal pre-admission AMIs. The clinical course of AMI was linked with CRA level.