1. Identification of sequence types among the M-nontypeable group A streptococci.
- Author
-
Relf WA, Martin DR, and Sriprakash KS
- Subjects
- Amino Acid Sequence, Australia, Bacterial Typing Techniques, Base Sequence, DNA, Bacterial genetics, Humans, Molecular Sequence Data, Polymerase Chain Reaction, Serotyping, Streptococcal Infections microbiology, Streptococcus pyogenes genetics, Streptococcus pyogenes isolation & purification, Streptococcus pyogenes classification
- Abstract
Streptococcal diseases, namely, acute glomerulonephritis and acute rheumatic fever, are common features in the aboriginal population of the Northern Territory of Australia. We examined the group A streptococcal M types identified during various surveys conducted since 1987. Streptococci were predominantly isolated from skin infections. A high proportion of the isolates could not be serotyped by conventional means and were designated M nontypeable (MNT). M-specific DNA sequences from the MNT isolates were examined, and sequence types were proposed for the classification of MNTs. This allowed a more precise estimate of the M types present in a population study.
- Published
- 1992
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