1. Characterization of 2 Neisseria gonorrhoeae Strains With High-Level Azithromycin Resistance Isolated in 2015 and 2018 in Japan.
- Author
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Shimuta K, Lee K, Yasuda M, Furubayashi K, Uchida C, Nakayama SI, Takahashi H, and Ohnishi M
- Subjects
- Anti-Bacterial Agents pharmacology, Anti-Bacterial Agents therapeutic use, Australia, Azithromycin pharmacology, Ceftriaxone pharmacology, Drug Resistance, Bacterial genetics, Humans, Japan epidemiology, Microbial Sensitivity Tests, Gonorrhea drug therapy, Gonorrhea epidemiology, Neisseria gonorrhoeae genetics
- Abstract
Abstract: We identified and characterized the first 2 Neisseria gonorrhoeae strains with high-level azithromycin resistance isolated in Japan. These were in the clade of ceftriaxone- and azithromycin-resistant strains isolated in Australia and the United Kingdom. The multilocus sequence typing, N. gonorrhoeae multiantigen sequence typing, and N. gonorrhoeae sequence typing for antimicrobial resistance types of these strains were found in gonococci from eastern Asia., Competing Interests: Conflict of Interest and Sources of Funding: This work was partly supported by Japan Agency for Medical Research and Development (grant number 18fk0108062), JSPS KAKENHI (grant number JP18K09163), and the Ministry of Health, Labour, and Welfare of Japan (grant H30-Shinkou-Ippan-004). The authors declare no conflicts of interest directly relevant to the content of this article., (Copyright © 2020 American Sexually Transmitted Diseases Association. All rights reserved.)
- Published
- 2021
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