1. Bloodstream infections and multidrug resistant bacteria acquisition among burns patients in Australia and New Zealand: A registry-based study.
- Author
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Cleland, Heather, Stewardson, Andrew, Padiglione, Alex, and Tracy, Lincoln
- Subjects
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MULTIDRUG resistance in bacteria , *CARBAPENEM-resistant bacteria , *BURN patients , *METHICILLIN-resistant staphylococcus aureus , *KLEBSIELLA pneumoniae , *INFECTION prevention - Abstract
This study interrogates infection related data in the Burns Registry of Australia and New Zealand (BRANZ), to examine associations of multi-drug resistant organisms (MDROs) and blood stream infection (BSI). Data between July 2016 and June 2021 were analysed to determine prevalence, risk factors and outcomes associated with BSIs and MDROs: Methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), carbapenem-resistant Pseudomonas spp. (CRP), and carbapenem-resistant Enterobacter (CRE). Data completeness and value for quality improvement activity were assessed. We found a low incidence (3.4%) of the resistant organisms of interest, and no change over the study period. Fequency varied between services and increased with age and size of burn. MRSA was the commonest organism in all age groups. A positive BSI result occurred in 1.6% of patients (12.1% of cultures taken) at a median time of 10.2 days post injury. Free text identification of organisms was inconsistently documented. The low rate and patterns of acquisition of MDROs of interest and BSIs is comparable with reports from countries with low incidence of massive burns. Wider adoption of a standardized laboratory reporting framework would help realise the potential of clinical quality registries to provide data which supports evidence based infection prevention initiatives. • The registry has excellent data completeness for resistant organism items. • Overall frequency of multi-drug resistant organisms is low, but high in patients with massive burns. • Frequency of acquisition did not increase during the study. • MRSA acquisition is not associated with poorer outcomes in adults with severe burns. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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