1. Patent Issued for Methods for protein ligation and uses thereof (USPTO 11807671).
- Subjects
LIFE sciences ,DIAMINO amino acids ,PEPTIDES ,PROTEINS ,AMINO acids - Abstract
A patent has been issued for methods of protein ligation and their uses. Protein ligation is an important tool in molecular biology and has applications in various life science disciplines. The patent describes the use of isopeptide bonds, which are covalent bonds between certain amino acids, for protein ligation. These bonds have advantages such as spontaneous formation, irreversibility under biological conditions, and resistance to proteases. The invention aims to provide new protein ligation technologies, including reversible protein ligation, to overcome limitations and increase the complexity and flexibility of protein structures. The patent also includes specific claims related to peptide tags and binding partner pairs for protein ligation. [Extracted from the article]
- Published
- 2023