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A recent study conducted by the Institute of Nuclear Medicine and Allied Sciences in Delhi, India, explored the binding interactions between a chalcone derivative called L1 and bovine serum albumin (BSA). The researchers used various spectroscopic techniques and computational studies to analyze the formation of a BSA-L1 complex. The study found that L1 predominantly bound to BSA through hydrogen bonds and Van der Waals forces. These findings contribute to the understanding of the potential therapeutic properties of chalcone derivatives. [Extracted from the article]

Keywords: Chengdu; People's Republic of China; Asia; Alcohol Oxidoreductases; Chalcones; Enzymes and Coenzymes; Health and Medicine; Hyperuricemia; Oxidase; Propiophenones; Proteins; Proteomics; Xanthine Oxidase EN Chengdu People's Republic of China Asia Alcohol Oxidoreductases Chalcones Enzymes and Coenzymes Health and Medicine Hyperuricemia Oxidase Propiophenones Proteins Proteomics Xanthine Oxidase 2023 FEB 10 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Current study results on Hyperuricemia have been published. Additionally, kinetics studies demonstrated that 15b presented a reversible and competitive XO inhibitor, which spontaneously combined with XO through hydrophobic force, and finally changed the secondary conformation of XO. Chengdu, People's Republic of China, Asia, Alcohol Oxidoreductases, Chalcones, Enzymes and Coenzymes, Health and Medicine, Hyperuricemia, Oxidase, Propiophenones, Proteins, Proteomics, Xanthine Oxidase. [Extracted from the article]