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The aim of this study is to determine the incidence and frequency of oral maxillofacial tumour reported by Department of Oral Pathology and Oral Medicine, Faculty of Dentistry Universiti Kebangsaan Malaysia (UKM) during the five years period from 1999 to 2003. A total of 226 reports were reviewed. Majority of the specimens reported were sent by the oral surgeons and dental practitioners in the Oral Maxillofacial Unit Hospital Universiti Kebangsaan Malaysia (HUKM), Faculty of Dentistry UKM and Oral Health Division, Kementerian Pertahanan Malaysia. Two hundred and nine diagnosed tissues (87%) were of benign in nature and 17 (7.5%) were malignant. Pyogenic granuloma was the most common lesion with 23 cases (10.2%) reported, followed by squamous cell carcinoma (6.6%), fibroepithelial polyp / fibrous epulis (6.2%), mucous extravasation cyst (6.2%) and ameloblastoma (6.2%). Of the 17 malignancies retrieved, squamous cell carcinoma (n=15) was the most predominant. The relative frequencies of most oral maxillofacial tumour seen in UKM dental faculty are comparative to most similar surveys in the literature particularly with the ones in South East Asia region. Squamous cell carcinoma was ranked 2nd in the series of diagnosed lesion and was the commonest malignancy seen. [ABSTRACT FROM AUTHOR]