1. Understanding the virulence of Streptococcus suis: A veterinary, medical, and economic challenge.
- Author
-
Haas B and Grenier D
- Subjects
- Animals, Anti-Bacterial Agents therapeutic use, Asia epidemiology, Bacterial Proteins physiology, Bacterial Vaccines, Drug Resistance, Multiple, Bacterial, Global Health, Humans, Serogroup, Streptococcal Infections economics, Streptococcal Infections epidemiology, Streptococcal Infections prevention & control, Streptococcus suis classification, Streptococcus suis genetics, Streptococcus suis immunology, Swine, Swine Diseases economics, Swine Diseases epidemiology, Swine Diseases prevention & control, Vaccination veterinary, Virulence, Zoonoses, Streptococcal Infections veterinary, Streptococcus suis pathogenicity, Swine Diseases microbiology
- Abstract
Streptococcus suis is a major swine pathogen worldwide and causes considerable economic losses in the swine industry. S. suis is also an emerging zoonotic agent, mainly in Asia. In pigs and humans, S. suis can cause septicemia, pneumonia, endocarditis, arthritis, and meningitis with irreversible sequelae. Identification and characterization of the virulence factors produced by S. suis are major advances in the understanding of the pathogenesis of S. suis infections and has therefore opened promising avenues for vaccine development against this pathogen. This literature review aimed to update the current knowledge of the virulence mechanisms of S. suis and of the vaccination strategies tested until now., (Copyright © 2017 Elsevier Masson SAS. All rights reserved.)
- Published
- 2018
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