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The purpose of this study is to examine the linguistic and non-linguistic goals of the Southeast Asian languages (SEAL) policy in Taiwan. It was proposed by former President Ma Ying-jeou's administration to develop grades 1-12 students' multilingual awareness, for there has been an increasingly significant presence of second-generation Southeast Asian immigrants at school. Since current President Tsai In-Wen's first-term in 2016, the SEAL policy has been fuelled with an economic and sociopolitical agenda -- the New Southbound Policy, the measure which is designed to advance the nation's prospects in Southeast Asia. This study applies Cooper's [1989. "Language Planning and Social Change." New York, NY: Cambridge University Press] language policy as marketing and analyses the instrumentalist value of the SEAL. The Tsai government is conceptualised as a marketer; the SEAL are defined as the "product"; the Ministry of Education is assigned to the "place" as a hub which distributes the SEAL product to nationwide consumers; "promotion" piques the consumers' interest in SEAL learning; "price" is set by making one's profit gains larger than the sum of investment. The study concludes that the value of the SEAL product increases when its communication network is expanded from local immigrant communities and national school systems to an international business area.

To facilitate the management of multidrug-resistant (MDR) tuberculosis, two nucleic acid sequence-based methods, the GenoType MTBDRplus test and DNA sequencing, were assessed for the rapid detection of drug-resistant Mycobacterium tuberculosis for the first time in the Asia-Pacific region. The performances of these two assays in detecting the presence of rifampin (rifampicin) (RIF) and isoniazid (INH) resistance-associated mutations in the rpoB, katG, inhA regulatory region, inhA, and oxyR-ahpC genes were compared to that of a conventional agar proportion drug susceptibility test. A total of 242 MDR and 30 pansusceptible M. tuberculosis isolates were evaluated in this study. The sensitivities obtained for RIF-resistant detection by the GenoType MTBDRplus test and by resistance gene sequencing were 95.5% and 97.9%, respectively. The sensitivities for INH resistance detection by the GenoType MTBDRplus test and by resistance gene sequencing were 81.8% and 93.4%, respectively. Together, the sensitivity for MDR tuberculosis detection was 78.5% with the GenoType MTBDRplus test and 91.3% by resistance gene sequencing. The specificity for RIF resistance, INH resistance, and MDR detection was 100% by both methods. The GenoType MTBDRplus test has the advantage of a short turnaround time for drug-resistant M. tuberculosis detection. Overall, the two assays performed equally well in detecting RIF resistance (P = 0.13). However, DNA sequencing demonstrated superior performance in detecting INH resistance (P < 0.001) and MDR tuberculosis (P < 0.001). We suggest that new alleles of INH resistance genes should be evaluated to improve the sensitivity of the GenoType MTBDRplus test, especially for different geographic areas with genetically diverse M. tuberculosis strains.