1. Prevalence of Tuberculosis Disease Among Adult US-Bound Refugees with Chronic Kidney Disease.
- Author
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Bardenheier, Barbara H., Pavkov, Meda E., Winston, Carla A., Klosovsky, Alex, Yen, Catherine, Benoit, Stephen, Gravenstein, Stefan, Posey, Drew L., and Phares, Christina R.
- Subjects
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TUBERCULOSIS risk factors , *TUBERCULOSIS epidemiology , *REFUGEES , *TUBERCULOSIS , *AGE distribution , *CAMPS , *CHI-squared test , *CONFIDENCE intervals , *MEDICAL records , *POISSON distribution , *REGRESSION analysis , *SEX distribution , *BODY mass index , *CROSS-sectional method , *DATA analysis software , *MIDDLE-income countries , *LOW-income countries , *ACQUISITION of data methodology , *ADULTS ,CHRONIC kidney failure complications - Abstract
The association between chronic kidney disease (CKD) and tuberculosis disease (TB) has been recognized for decades. Recently CKD prevalence is increasing in low- to middle-income countries with high TB burden. Using data from the required overseas medical exam and the recommended US follow-up exam for 444,356 US-bound refugees aged ≥ 18 during 2009–2017, we ran Poisson regression to assess the prevalence of TB among refugees with and without CKD, controlling for sex, age, diabetes, tobacco use, body mass index (kg/m2), prior residence in camp or non-camp setting, and region of birth country. Of the 1117 (0.3%) with CKD, 21 (1.9%) had TB disease; of the 443,239 who did not have CKD, 3380 (0.8%) had TB. In adjusted analyses, TB was significantly higher among those with than without CKD (prevalence ratio 1.93, 95% CI: 1.26, 2.98, p < 0.01). Healthcare providers attending to refugees need to be aware of this association. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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