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This article studies the rationalization of public health in the city of Rosario during the 1920s starting from the initiatives of the physician Manuel Pignetto during his administration. His Sanitary Plan constitutes a key perspective to analyze institutional fields, the creation of technical agencies, and the articulation of local and international debates in the rearrangement of municipal health devices. Through triangulation and the hermeneutics of official and journalistic documentary materials, we are able to address the possibilities and the limits of a plan that reinforced municipal competencies regarding public health under a new social perspective. [ABSTRACT FROM AUTHOR]