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Your search keyword '"ORAL leukoplakia"' showing total 2 results
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2 results on '"ORAL leukoplakia"'

1. Oral squamous cell carcinomas and oral potentially malignant disorders: A Latin American study.

Author

Gilligan, Gerardo, Panico, René, Lazos, Jerónimo, Morelatto, Rosana, Belardinelli, Paola, Criscuolo, Maria Ines, Bolesina, Nicolas, Molina Ávila, Ignacio, Pimentel Solá, Juan Martin, Rivarola, Emilce, Morgante, Maria Jimena, Ingrassia Tonelli, Maria Eugenia, Gimenez, Javier, Doratti, Pablo, Werner, Laura Cecilia, Prado‐Ribeiro, Ana Carolina, Brandão, Thais Bianca, Vechiato‐Filho, Aljomar Jose, Cuzzullin, Maria Claudia, and Saldivia‐Siracusa, Cristina

Subjects
*SQUAMOUS cell carcinoma, *RISK assessment, *STATISTICAL correlation, *MOUTH tumors, *T-test (Statistics), *HEAD & neck cancer, *PRECANCEROUS conditions, *SCIENTIFIC observation, *SEX distribution, *SMOKING, *RETROSPECTIVE studies, *AGE distribution, *CHI-squared test, *ORAL leukoplakia, *DESCRIPTIVE statistics, *CANCER patients, *ORAL diseases, *RESEARCH, *ALCOHOL drinking, *DISEASE risk factors, *DISEASE complications, *SYMPTOMS, LIP tumors, TONGUE tumors
Abstract

Objective: To determine the frequency of oral squamous cell carcinoma (OSCC) associated or not with oral potentially malignant disorders (OPMD), and the epidemiological profile and traditional risk factors in Latin America. Methods: A retrospective observational study was conducted in 17 Latin American centres. There were included cases of OSCC, analysing age, gender, OSCC and their association with previous OPMD. Clinicopathological variables were retrieved. The condition of sequential‐OSCC versus OSCC‐de novo (OSCC‐dn) was analysed concerning the aforementioned variables. Quantitative variables were analysed using Student's t‐test, and qualitative variables with chi‐square. Results: In total, 2705 OSCC were included with a mean age of 62.8 years old. 55.8% were men. 53.75% of the patients were smokers and 38% were common drinkers. The lateral tongue border was the most affected site (24.65%). There were regional variations in OPMD, being leukoplakia the most frequent. Of the overall 2705 OSCC cases, 81.4% corresponded to OSCC‐dn, while s‐OSCC were 18.6%. Regarding lip vermillion SCC, 35.7% corresponded to de novo lip SCC and 64.3% were associated with previous OPMD. Conclusions: In Latin America, OSCC‐dn seems to be more frequent with regional variations of some clinical and histopathological features. Further prospective studies are needed to analyse this phenomenon. [ABSTRACT FROM AUTHOR]

Published
2024
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2. What is the frequency of floor of the mouth lesions? A descritive study of 4,016 cases.

Author

Paiva e Costa, Anderson Mauricio, Corrêa Pontes, Flávia Sirotheau, Lacerda de Souza, Lucas, Ajudarte Lopes, Márcio, Roger Santos-Silva, Alan, Santos-Silva, Roger, Benevenuto de Andrade, Bruno Augusto, Tambasco Bezerra, Kelly, José Romañach, Mário, Santiago Gomez, Ricardo, Nayara Libório-Kimura, Rafael Ferreira e Costa, Pinto Júnior, Décio dos Santos, da Cruz Perez, Danyel Elias, Lisboa de Castro, Jurema Freire, Nayara Libório-Kimura, Tatiana, Câmara, Jeconias Câmara, Mendes Penafort, Paulo Victor, Paiva Fonseca, Felipe, Paes de Almeida, Oslei, and Mosqueda-Taylor, Adalberto

Subjects
SOFT tissue tumors, ORAL leukoplakia, HISTOPATHOLOGY, SQUAMOUS cell carcinoma, SALIVARY glands, DIAGNOSIS, ORAL mucosa
Abstract

Background: The aim of this study was to investigate the frequency of oral lesions in the floor of the mouth from representative oral pathology centres in Latin America. Material and Methods: This study was conducted on biopsies obtained from January of 1978 to December of 2018 at nine Latin America oral and maxillofacial pathology centres. Gender, age and histopathological diagnosis were evaluated. Data were analysed using descriptive methods. Chi-square test was used for pairwise comparisons. Results: From 114,893 samples, 4,016 lesions (3.49%) occurred in the floor of the mouth. Brazil showed 3,777 cases (94%), Mexico 182 cases (4.5%) and Argentina 57 cases (1.4%). Benign lesions represented 65.1% (2,617 cases), followed by 34.9% (1,404 cases) of malignant disorders. Lesions of epithelial origin were more frequent (1,964 cases; 48.9%), followed by salivary glands (1,245 cases; 31%) and soft tissue lesions (475 cases; 11.7%). The most common histological subtypes were oral squamous cell carcinoma (1,347 cases; 33.5%), ranula (724 cases; 18%), oral leukoplakia (476 cases; 11.8%) and inflammatory fibrous hyperplasia (239 cases; 5.9%). The lesion affected males in 2,129 cases and females in 1,897 cases. Conclusions: In the current study, lesions in the floor of the mouth represented 3.49% of biopsies submitted to oral pathology services and oral squamous cell carcinoma, ranula and leukoplakia were the most common lesions. [ABSTRACT FROM AUTHOR]

Published
2021
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