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Objectives: The paleontological description and comparative analysis using discrete morphology, morphometrics (linear and geometric) and cross‐sectional geometry of three femoral diaphyseal sections from the Middle Pleistocene site of Hualongdong, China. Materials and Methods: The material consists of the original Hualongdong femoral fossils and available data on femoral diaphyses from Middle and Late Pleistocene archaic humans and Middle and earlier Upper Paleolithic modern humans. The methods include visual observation, diaphyseal diameters, cross‐sectional parameters (transverse areas and second moments of area derived from micro‐CT scans), and geometric morphometrics using semilandmark data. Results: The Hualong 11 midshaft section is similar to other Middle and Late Pleistocene archaic humans in being transversely broad and lacking a pilaster despite a prominent linea aspera. It clusters principally with archaic human femora in all measured parameters. The Hualong 15 and 16 subtrochanteric pieces are similar to many Middle Pleistocene and early modern human femora in being transversely broad. In particular, Hualong 15 exhibits a prominent lateral (gluteal) buttress, similar to many Upper Paleolithic femora but also the Lazaret and Krapina archaic ones. In addition, Hualong 15 has a small third trochanter, a common Upper Paleolithic but rare earlier feature. Discussion: The Hualong 11 femoral piece reinforces the general Middle Pleistocene pattern, especially for eastern Eurasia from which archaic human femora are rare. The subtrochanteric proportions of Hualong 15 and 16 reinforce the Early Pleistocene and (generally) Middle Pleistocene pattern of bone distributions, but their subperiosteal contours align them (along with those of the Lazaret and Krapina femora) with Upper Paleolithic ones. It is difficult to account for these proportions from the generally broad pelves of Pleistocene archaic humans. [ABSTRACT FROM AUTHOR]

Background: Coronavirus disease 2019 (COVID-19) has spread rapidly in China and other overseas areas, which has aroused widespread concern. The sharp increase in the number of patients has led to great psychological pressure on health care workers. The purpose of this study was to understand their mental health status and needs, so as to provide a scientific basis for alleviating the psychological pressure of health care workers. Methods: Using a cross-sectional study design, 540 health care workers were randomly selected from two designated tuberculosis medical institutions in Anhui Province. The basic situation, perceived social support, depression level, loneliness and COVID-19 related knowledge were collected and analyzed by questionnaire. Results: A total of 511 valid questionnaires were finally retrieved. There were 139 people in epidemic prevention and control positions (27.20%). Depression level: People in isolation ward, fever clinic and pre-check triage were at the level of mild to moderate depression. Female was higher than male; nurse was higher than doctor; middle and junior job titles were higher than senior titles; junior college degree or below were higher than bachelor's degree, master's degree and above; isolation ward, fever clinic and pre-check triage were significantly higher than those of non-prevention and control positions (p < 0.05). Loneliness scores: Doctors were higher than that of medical technicians, and isolation ward, fever clinic and pre-check triage were higher than those of other medical departments (p < 0.05). Social support: Doctors were lower than that of medical technicians, and isolation ward, fever clinic and pre-check triage were significantly lower than those of other departments (p < 0.05). The score of social support was negatively correlated with depression and loneliness (p < 0.001), while depression was positively correlated with loneliness (p < 0.001). Health care workers most want to receive one-to-one psychological counseling (29.75%), and provide crisis management (24.07%). The awareness rate of health care workers on COVID-19's knowledge was relatively high. Conclusions: The psychological problems of health care workers, especially women, nurses with low educational background, low professional title, and staff in the epidemic prevention and control positions are relatively serious. [ABSTRACT FROM AUTHOR]

Objective: Pulmonary tuberculosis (TB) is a severe infectious respiratory disease, the burden of which remains high in China. To provide scientific evidence for developing more targeted prevention and control strategies, this study aimed to determine the incidence trends and explore the epidemiological characteristics of pulmonary TB in Anhui Province, Eastern China between 2013 and 2018. Methods: The retrospective study analyzed information regarding pulmonary TB cases reported by the National Infectious Disease Reporting System and census data collected from the Anhui Provincial Bureau of Statistics. Results: Overall, 211,892 cases of TB patients were reported in Anhui Province, China between 2013 and 2018, with an average annual reported incidence rate of 57.7 per 100,000 persons. A significant decrease in the incidence rate of pulmonary TB (p < 0.001) was observed during the study period. Men had a higher incidence rate of pulmonary TB than women (p < 0.001). The highest annual average reported incidence rate was 204.2 per 100,000 persons in those aged 70–74 years. The number of farmers with pulmonary TB, i.e., 155,415, accounted for 73.4% of all cases. Moreover, the peak period of reported cases was from January to March. Four cities along the Yangtze River—Anqing, Tongling, Chizhou, and Wuhu—reported significantly higher incidence rates of pulmonary TB than other cities (p < 0.001). Conclusions: From 2013 to 2018, there was a significant decline in the incidence rate of pulmonary TB in Anhui Province, with peaks occurring from January to March. Prevention and control strategies targeting men, people aged 70–74 years, farmers, and the four cities along the Yangtze River should be strengthened. [ABSTRACT FROM AUTHOR]

• Granitoids in the Jingde-Guangde area formed in two stages: 152–135 Ma and 135–130 Ma. • Early and late stages were identified to be I-type and I-A transform-type respectively. • Two stages granitoids were formed under different temperatures and oxygen fugacities. • Both granites were derived from Neoproterozoic crust. • The driving force of two igneous events was the paleo-Pacific subduction. The eastern Jiangnan Orogen comprises two tectonic units: the initial defined Jiangnan Orogen (IJO) and the eastern extension area of the Jiangnan Orogen (EEJO). Ten granitoid intrusions with ages from 152 to 130 Ma in the EEJO, were selected for integrated studies. Therein, I-type granodiorites and monzogranites (152–135 Ma) had SiO 2 contents of 62.5–69.0 wt%, total alkali contents of 6.2–7.9 wt%, and a narrow range of A/CNK (0.91–1.03). They also showed enrichment of LILE, depletion in HFSE, slightly Eu negative anomalies. I-A transform-type monzogranites and K-feldspar granites (135–130 Ma) exhibited a systematic higher SiO 2 (64.6–74.5 wt%) and total alkali contents of 7.8–10.1 wt%, but low Al 2 O 3 (13.42–15.75 wt%), Fe 2 O 3 T (1.29–4.00 wt%), MgO content (0.16–1.32 wt%) with more significant Eu and Sr negative anomalies. Whole rock ε Nd (t) and 87Sr/86Sr(t) values of the granodiorite-monzogranites fall into the ranges of −8.8 to −6.1 and 0.7080–0.7112, respectively. Their ε Hf (t) and δ18O values are from −11.4 to −3.1 and 7.12‰ to 10.03‰. The monzogranites and K-feldspar granites show relatively higher ε Nd (t) values (−6.1 to −5.4) and narrow 87Sr/86Sr(t) ratios (0.7086–0.7104). Their ε Hf (t) and δ18O values range from −9.3 to −3.3 and 7.23‰ to 10.09‰. These rocks dominantly derived from partial melting of the early Neoproterozoic accretionary crust, indicating that the EEJO should belong to the Jiangnan Orogen. The presence of I-A transform-type rocks implies that the tectonic geodynamic frame transformed from compression to extension might have took place at 135 Ma. [ABSTRACT FROM AUTHOR]

Most W mineralization in the world is genetically related with highly fractionated granitoids, but little is known about petrogenesis of weakly fractionated granitoids and its relationship with W mineralization. To reveal the petrogenesis of the weakly fractionated granitic rocks and related mineralization, a combined study of zircon U Pb ages, whole-rock major-trace elements and Sr-Nd-Pb isotopes as well as apatite in-situ geochemistry was carried out for the Ningguo-Guangde granitoids in the world-class Jiangnan W belt (total resource of approximately 6.06 Mt WO 3), China. Zircon U Pb ages indicate that the Ningguo-Guangde granitoids were emplaced in the Early Cretaceous (ca. 138–125 Ma). These samples with moderate silicon (SiO 2 = 65.5–68.4 wt%) mainly consist of high-K calc-alkaline granodiorites and monzogranites, which exhibit an affinity for the weakly fractionated I-type granite, with enrichment in light rare earth elements (LREEs), Rb, Th and U, and negative Eu (δEu = 0.64–0.91), Nb, P and Ti anomalies. All samples have Mg# values of 40.3–51.2, Sr contents of 266–411 ppm and Sr/Y ratios of 9.11–29.6, negative whole-rock εNd(t) values (−6.6 to −5.1), high radiogenic Pb isotopic compositions, and high logfO 2 values (−21.7 to −12.0). The integrated interpretation of geochemical data show that the Ningguo-Guangde granitoids were likely originated from Neoproterozoic crustal components mixing with metasomatized mantle-derived magmas. A comprehensive discriminant analysis indicates that metal-rich magma source, shallow fractional crystallization and high oxygen fugacity were favorable factors for the weakly fractionated I-type granite-related W Mo mineralization in southern region of Anhui Province, eastern China. Furthermore, porphyry or skarn W Mo deposits can be regarded as important exploration targets in the Ningguo-Guangde region. • The Early Cretaceous weakly fractionated granitoids were derived from mixing of crust-mantle • Source, fractional crystallization and high logfO 2 are favorable factors for mineralization • Porphyry or skarn W-Mo deposits are important exploration targets [ABSTRACT FROM AUTHOR]