1. Perioperative complications of splenectomy for hematologic disease.
- Author
-
MacRae HM, Yakimets WW, and Reynolds T
- Subjects
- Adult, Alberta epidemiology, Bacterial Infections epidemiology, Blood Loss, Surgical statistics & numerical data, Female, Humans, Lymphoproliferative Disorders surgery, Male, Middle Aged, Myeloproliferative Disorders surgery, Platelet Count, Purpura, Thrombocytopenic surgery, Regression Analysis, Retrospective Studies, Spleen pathology, Splenectomy statistics & numerical data, Splenic Diseases surgery, Survival Rate, Hematologic Diseases surgery, Postoperative Complications epidemiology, Splenectomy adverse effects
- Abstract
A 15-year study of perioperative complications was carried out in 142 adults who underwent splenectomy for hematologic disease at the University of Alberta Hospital in order to obtain recent statistics on morbidity and mortality. The patients were grouped into four diagnostic categories: idiopathic thrombocytopenic purpura (71 patients), lymphoproliferative disorders (34 patients), myeloproliferative disorders (12 patients) and miscellaneous disorders (25 patients). Splenectomy was carried out for therapeutic reasons in 93% of patients and to establish a diagnosis in 7%. The overall complication rate was 22% (31 of 142) and the death rate was 6% (7 of 142). Infection accounted for 42% of the complications. Steroid or antibiotic therapy preoperatively did not significantly affect the infection rate. Drains, if removed within the first week, also did not affect the postoperative infection rate. Spleen size and the interaction between diagnosis and the presence of thrombocytopenia were predictors of the need for intraoperative transfusion.
- Published
- 1992