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Introduction: Dengue fever is one of the most common arboviral mediated outbreaks reported with increased prevalence year after year with considerable morbidity and mortality. This study was designed to assess the clinical and biochemical parameters of dengue fever patients. Materials and methods: Prospective observational study was undertaken among adult patients in a Civil Hospital, Ahmedabad. Fifty patients were studied and analyzed. All patients who were NS1 antigen/IgM dengue positive were included in the study. Clinical features, hematological and biochemical parameters were noted. Results: Of the 50 patients studied, majority were males (64%). Fever was the major symptom (100%) followed by headache (96%), myalgia (94%), retro-orbital pain (64%), conjunctival injection (24%), rash (38%), abdominal pain (74%), pleural effusion (30%) and ascites (26%). Significant derangements in platelet (70%), leucocyte counts (78%) and serum transaminases (74%) were noted. Mortality rate was zero. Conclusion: Fever associated with headache, retro-orbital pain, erythematous morbilliform rash, conjunctival suffusion and itching in palms and soles along with thrombocytopenia, leucopenia, elevated liver transaminases should prompt a clinician on the possibility of dengue infection. Platelet transfusions have little role in management of dengue patients. [ABSTRACT FROM AUTHOR]

Background: WHO announced influenza A H1N1 as pandemic (commonly known as swine flu) in 2009; but every year there is increase in influenza A H1N1 positive cases causing epidemics of febrile respiratory illness due to genetic re-assortment in influenza virus. This study aimed for clinical profile of patient with influenza A H1N1 and its outcome admitted at civil hospital Ahmedabad. Materials and methods: Present study was included 50 patients with influenza A H1N1; admitted in B.J. Medical College and Civil Hospital, Ahmedabad. This study was carried out for one year from June 2018 to June 2019. Patients were studied and managed as per standard Government of India protocol. Results: Total 50[19 (38%) males and 31 (62%) females] patients were studied for clinical spectrum, complications and outcome. All patients had fever (100%), dry cough in 92% of patients, throat pain in 88% of patients, breathlessness in 54% of patients, headache in 48% of patients, sputum production in 40% of patients and hemoptysis in 6% of patients. 35 (70%) patients had comorbidity. Total13 (26%) patients were complicated; out of which 4 (8%) patients required ventilatory support. Conclusion: Early case detection, categorizations according to symptoms prevention of treatment has better outcome and decreases disease related morbidity and mortality and burden of disease in community and voluntary early reporting should be encouraged through various health campaigns. [ABSTRACT FROM AUTHOR]