1. Ebola Therapeutic Study and Future Directions.
- Author
-
Lu DY, Wu HY, Yarla NS, Lu TR, Xu B, and Jian-Ding
- Subjects
- Africa epidemiology, Disease Outbreaks prevention & control, Ebolavirus drug effects, Ebolavirus immunology, Ebolavirus isolation & purification, Hemorrhagic Fever, Ebola epidemiology, Hemorrhagic Fever, Ebola immunology, Hemorrhagic Fever, Ebola virology, Humans, Survival Rate, Viral Vaccines immunology, Antiviral Agents therapeutic use, Ebolavirus pathogenicity, Hemorrhagic Fever, Ebola therapy, Viral Vaccines therapeutic use
- Abstract
The constant Ebola epidemic outbreaks in Africa arisen in waves of panic worldwide. There is a high mortality rate (30-70%) among the Ebola-infected people in virus- stricken areas. Despite these horrors, the medical capabilities against this deadly viral disease were provided by limited therapeutic agents/options. As a result, several patented agents, biotherapies or prophylactic/therapeutic vaccines need to be reviving into the global markets-including patents of small molecular chemicals, short sequences or oligomers of DNA/RNA, linkages of chemicals with bio-molecules, herbal medicine and so on. In addition, the possible mechanisms of action of these therapeutic options are underway. To promote Ebola biomedical study, the multiple characters of Ebola infections-its origin, pathologic progress, genomic changes, therapeutic context and economic considerations are outlined in this review. Finally, a great difference can be expected after these types of efforts., (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)
- Published
- 2019
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