1. Isolation of Nontuberculous Mycobacteria in Southeast Asian and African Human Immunodeficiency Virus-infected Children With Suspected Tuberculosis.
- Author
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Borand L, de Lauzanne A, Nguyen NL, Cheng S, Pham TH, Eyangoh S, Ouedraogo AS, Ung V, Msellati P, Tejiokem M, Nacro B, Inghammar M, Dim B, Delacourt C, Godreuil S, Blanche S, and Marcy O
- Subjects
- Africa epidemiology, Asia, Southeastern epidemiology, Child, Child, Preschool, Clinical Laboratory Techniques, HIV, HIV Infections epidemiology, HIV Infections microbiology, Humans, Immunologic Deficiency Syndromes microbiology, Immunologic Deficiency Syndromes virology, Mycobacterium Infections, Nontuberculous epidemiology, Mycobacterium Infections, Nontuberculous microbiology, Mycobacterium avium Complex isolation & purification, Nontuberculous Mycobacteria classification, Prospective Studies, Tuberculosis diagnosis, Tuberculosis microbiology, HIV Infections complications, Immunologic Deficiency Syndromes epidemiology, Mycobacterium Infections, Nontuberculous diagnosis, Nontuberculous Mycobacteria isolation & purification, Tuberculosis epidemiology
- Abstract
We enrolled 427 human immunodeficiency virus-infected children (median age, 7.3 years), 59.2% severely immunodeficient, with suspected tuberculosis in Southeast Asian and African settings. Nontuberculous mycobacteria were isolated in 46 children (10.8%); 45.7% of isolates were Mycobacterium avium complex. Southeast Asian origin, age 5-9 years, and severe immunodeficiency were independently associated with nontuberculous mycobacteria isolation., Clinical Trials Registration: NCT01331811., (© The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America.)
- Published
- 2019
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