1. [Primary nephrotic syndrome in the black African child].
- Author
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Gbadoé AD, Atakouma DY, Napo-Koura G, Gouna A, Akakpo-Maxwell O, Dogba MA, Tatagan-Agbi K, Késsié K, and Assimadi JK
- Subjects
- Adrenal Cortex Hormones administration & dosage, Africa, Child, Drug Resistance, Ghana, Humans, Nephrosis, Lipoid diagnosis, Nephrosis, Lipoid drug therapy, Nephrosis, Lipoid genetics, Nephrotic Syndrome diagnosis, Nephrotic Syndrome drug therapy, Togo, Black People genetics, Nephrotic Syndrome genetics
- Abstract
Idiopathic nephrotic syndrome (INS) in black African children differs from that of children in temperate areas. The main differences are the high rate of corticosteroid non-responders and the low rate of minimal change glomerulopathy in black African children, possibly related to a racial factor. The identification of a high corticosensibility in certain African regions (Togo and Ghana) can lead to the identification of an ethnic factor. Further genetic studies should be carried out in order to provide a better approach to INS in Africa.
- Published
- 1999
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